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Prof. Diah Ayu Maharani, DDS, PhD
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Makara Journal of Health Research
Published by Universitas Indonesia
ISSN : 23563664     EISSN : 23563656     DOI : https://doi.org/10.7454/msk
Core Subject :
Makara Journal of Health Research (MJHR) is a peer-reviewed and scientific journal published by Universitas Indonesia. Starting from 2019 onwards, MJHR is redirecting its scope, focusing on publishing research articles relevant to non-communicable diseases (NCDs) addressing issues of surveillance, disease management and health policy in the Asia Pacific and Mediterranean countries. Relevant academic articles regarding NCDs analyzed from an integrated perspective including individual and population level, experimental and clinical approaches, epidemiology, public health, disease prevention and health promotion, diagnosis, treatment, prognosis and palliative care are welcome.
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Articles 10 Documents
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Search results for , issue "Vol. 26, No. 1" : 10 Documents clear
Evaluation of Biochemical and Pathological Parameters at Different Doses of Cisplatin in Experimental Animal Model: Toxicological Study on an Antineoplastic Drug Sultana, Farhana; Islam, Muhammed Mohibul; Amin, Mohammad Nurul; Jahan, Nusrat; Kabir, Asma; Emran, Talha Bin; Sutradhar, Bibek Chandra; Banik, Sujan
Makara Journal of Health Research Vol. 26, No. 1
Publisher : UI Scholars Hub

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Abstract

Background: This study aimed to assess the effect of cisplatin-induced toxicities on biochemical and pathological parameters such as body, liver, and kidney weights, blood urea nitrogen (BUN), creatinine, alanine aminotransferase (ALT), and blood cells (RBCs and WBCs) in white Swiss albino mice. Methods: Cisplatin’s potential toxic effects on body, liver, and kidney weights were evaluated using standard laboratory methods. Blood biochemical levels such as BUN, creatinine, and ALT levels were determined by an auto-hemolyzer using commercial diagnostic kits. Blood cells (RBCs and WBCs) were counted under a microscope by a hemocytometer. Results: Cisplatin’s potential toxic effects on body, liver, and kidney weights were evaluated using standard laboratory methods. Blood biochemical levels such as BUN, creatinine, and ALT levels were determined by an auto-hemolyzer using commercial diagnostic kits. Blood cells (RBCs and WBCs) were counted under a microscope by a hemocytometer. Conclusions: This study suggested to increase caution when using cisplatin, particularly at high doses. Further investigation shall be performed to minimize its toxic effect and optimize its use.
Comparison of the Accuracies of CBCT, Radiography, and Four Electronic Apex Locators in Working Length Determination Özata, Merve Yeniçeri; Falakaloğlu, Seda; Kaya, Sadullah
Makara Journal of Health Research Vol. 26, No. 1
Publisher : UI Scholars Hub

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Background: One of the significant stages during endodontic procedures is determining the correct working length (WL). This study aimed to evaluate the accuracy of four electronic apex locators (EALs) (Root ZX mini, Raypex 6, Propex Pixi, and E-Pex Pro) and cone-beam computed tomography (CBCT) and radiographic measurement in determining the actual WL (A-WL). Methods: Thirty extracted single-root mandibular premolars were selected and flattened at the crown. The WL was determined by advancing the #15 K file until its tip was visible from the apical, and the A-WL was established by subtracting 0.5 mm from this length. The WL was also determined using periapical radiography, four EALs, and CBCT. The differences in all measurements were compared with the A-WL. The data were statistically analyzed using one-way analysis of variance (Welch) and Tamhane’s test. The significance level was set at p < 0.05. Results: Compared with other measurement methods, CBCT gave shorter values than the A-WL, and this finding was statistically significant compared with those of the PR and Propex Pixi groups (p = 0.009) (p = 0.024). No significant difference was observed between the other groups (p > 0.05) except the CBCT group (p < 0.05). Conclusions: Root ZX mini and Raypex 6 made measurements close to the A-WL.
Factors Associated with Independent National Health Insurance Ownership among Reproductive Aged Women in Indonesia Widiarti, Ika Putri; Idris, Haerawati
Makara Journal of Health Research Vol. 26, No. 1
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Background: Indonesia has been aiming toward universal health coverage since 2019, but it has yet to be achieved. The National Health Insurance (NHI) program provides individual services for women of reproductive age who require health care before pregnancy, during pregnancy, and at the time of labor. This study aims to analyze factors associated with independent NHI ownership among women of reproductive age in Indonesia. Methods: Secondary data from the Wave 5 Indonesia Family Life Survey (IFLS) involving 2,084 women of reproductive age were used. The chi-square test and logistic regression test were used for data analysis. Results: The percentage of women of reproductive age who have independent NHI was 48.4%. Age, region, residence, education, marital status, employment status, chronic disease history, health perception, and economic status were associated with the independent NHI ownership. Urban was found to be a predictor for insurance ownership. Conclusions: Women of reproductive age who live in urban areas are more likely to have NHI than those in rural areas. The Indonesian government should improve NHI ownership equality by expanding health insurance coverage in rural areas.
Prevalence and Risk Factors of Hypertension and Diabetes Mellitus among the Indonesian Elderly Oktaviyani, Prisilia; salman, Salman; Sari, Marlynda Happy Nurmalita; Frisilia, Melisa; Munazar, Munazar; Satria, Ana; Maretalinia, Maretalinia
Makara Journal of Health Research Vol. 26, No. 1
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Background: Epidemiological and demographic transitions lead to the emergence of non-communicable diseases (NCD) among the elderly. This study aimed to examine the risk factors of hypertension and diabetes mellitus (DM) among the elderly by using secondary data (Basic Health Research 2018). Methods: Secondary data from Basic Health Research (N = 88,911) were used. Cut-off values for measurement were WHO standard of 126 mg/dl for fasting and 200 mg/dl for non-fasting for DM and 140 mmHg for systole and 90 mmHg for diastole for hypertension. Univariate, bivariate, and multivariate (binary logistic regression) analyses were conducted using STATA version 15. Results: The prevalence of hypertension and DM among the elderly was about 22.30% and 5.39%, respectively. Age, sex, educational level, marital status, place of residence, and employment status were substantially associated with hypertension and were risk factors for DM. Conclusions: There is significant correlation between hypertension and DM are risk factors of one another and therefore show a relationship. Various sectors must develop appropriate programs, including community and family support, to address this situation.
Identification of Risk Factors Associated with Nasopharyngeal Carcinoma (NPC) in the Pahang State of Malaysia Hospitals Ahmad, Azmir; Basha, Muzaitul Akma Mustapa Kamal; Yassin, Wardah Mohd.; Rahman, Nor Azlina A.; Leman, Wan Ishlah; Rosla, Luqman; Yussof, Sharifah Nor Ezura Syed; Paul, Mark; Awang, Kamariah Mohamed; Abdullah, Kahari; Kaderi, Mohd. Arifin
Makara Journal of Health Research Vol. 26, No. 1
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Background: Nasopharyngeal carcinoma (NPC) is the fifth most common cancer reported in Malaysia. Although several studies on NPC have been carried out, the risk factors associated with NPC in Malaysia are unknown. Therefore, this study was designed to investigate the risk factors associated with NPC cases in Pahang state. Methods: NPC cases that were diagnosed between 2012 and 2017 were recruited from two referral hospitals in Pahang. An interview was conducted using adapted questionnaires, which included demographic data, family history of cancer, and lifestyle. The data were analyzed statistically to identify the associations between the selected variables and NPC. Results: A total of 71 NPC cases and 81 control subjects were recruited from the hospitals. Multivariate analysis showed that a family history of NPC and current smoking were significantly associated with the risk of NPC (p < 0.05). Further analysis revealed a significant association between the risk of NPC in smokers with no family history of NPC (p < 0.05). Conclusions: This preliminary study suggests that family history and smoking are factors associated with the development of NPC in Pahang, which was consistent with previous studies.
Trends and Determinants of Using Delivery Assistance by Health Workers: A Secondary Analysis Using the 2007–2017 Indonesian Health and Demographics Survey Idris, Haerawati; Syafriyanti, Willyana
Makara Journal of Health Research Vol. 26, No. 1
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Background: The World Health Organization reports that approximately 295,000 women died during or after their pregnancy and delivery in 2017. However, such deaths can be prevented by using delivery assistance from health workers. This study aims to analyze the trends and determinants of using delivery assistance by health workers in Indonesia. Methods: A quantitative cross-sectional design is adopted to analyze secondary data from the Indonesian Health Demographic Surveys in 2007, 2012, and 2017. The sample includes married women that are selected according to inclusion and exclusion criteria: 15.011 respondents in 2007, 14.989 in 2012, and 15.179 in 2017. Data are analyzed using logistic regression statistical tests. Results: This study shows the significant increase of using delivery assistance by health workers in Indonesia, from 53.8% in 2007, 68.8% in 2012, to 77.9% in 2017. Age, residence in the Java/Bali region, residence in urban areas, high and secondary education, high economic status, complete antenatal care visits, and knowing the signs of danger during pregnancy have significant relationships with delivery assistance by health workers among women. After being controlled by another factor, higher education is the most dominant factor associated with using delivery assistance by health workers among women in Indonesia (p < 0.001; Prevalence Ratio (PR) of 3.727 (3.123–4.447). Conclusions: Women’s education is the most important factor in delivery assistance by health workers utilization. Increasing knowledge regarding utilization of health worker assistance during delivery can be carried out through educational information, counseling or seminars, the Internet, and other media that are expected to increase information and awareness to take advantage of such service.
Investigating the Links Between Body Composition and Female University Students’ Night Eating Habits and Sleep Quality Rosli, Hanisah; Mat Ludin, Arimi Fitri; Lim, Amanda Priscilla; Vallavan, Vimalah; Sze Yuen, Lew; Yusop, Norizatul Hidayah; Razali, Nur Athirah; Amran, Amerull Daneal; Asmadi, Nurfarahin; Othman, Mohd Sham
Makara Journal of Health Research Vol. 26, No. 1
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Background: Malaysia has the highest prevalence of obesity among Southeast Asian countries, and the current number is expected to increase further. In particular, the rate of obesity is reportedly increasing among females and young adults in Malaysia. Modern lifestyle habits, which include night eating and poor sleep quality, have been shown to increase the risk of obesity and high body fat. This study aims to determine the link between female university students’ body composition and their night eating habits and sleep quality. Methods: Body composition was measured using a Bioelectrical Impedance Analysis (BIA) analyzer. Night eating syndrome and sleeping pattern and quality were determined using the Night Eating Questionnaire (NEQ) and the Pittsburgh Sleep Quality Index (PSQI), respectively. Results: A total of 112 female students participated in this study, the majority (66.1%) of whom were categorized as having normal weight. Their body fat percentages (28.0 ± 6.1) were found to be lower than the standard value for Asian women. Most of the subjects were categorized as having normal night eating (93.8%) and poor sleep (76.8%) patterns. The correlation analysis results indicated significant relationships between sleep quality and night eating habit and body weight. Furthermore, analysis using binary logistic regression showed a protective relationship between muscle mass and sleeping habit. Conclusions: This study showed that the majority of the university students had poor sleep quality. This is an alarming finding. Therefore, further investigations on factors related to poor sleep quality among young adults are required.
Attitudes of Turkish Parents Toward Sex Education of Their Intellectual Disability Children Sarı, Hakan; Pürsün, Tuğba
Makara Journal of Health Research Vol. 26, No. 1
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Background: Legal regulations in Turkey state that it is a fundamental right for children with intellectual disability to receive sex education. However, such education is highly limited due to the negative attitudes of these children’s parents. Therefore, the main aim of this study is to evaluate the attitudes of Turkish parents toward the sexual education of their intellectually disabled children. Methods: This quantitative study used the survey method on 311 parents who have children with intellectual disabilities. Data collection was carried out using a Likert-type scale questionnaire developed by the author. Socio-demographic variables were attained, and the data collected were analyzed. Results: Most of the parents (85%) believe that their children need support for sexual education, but cannot improve themselves to teach such subject without undergoing such education as well. However, the parents appear to have positive attitudes toward sexual education for their intellectually disabled children and believe that it can be provided adequately. Conclusions: Turkish parents have positive attitudes toward sex education for their children intellectual disability children. Therefore, adequate information about sex education might be needed from the professionals to empower the parents.
Exploring the Experience of Stigma among People Living with HIV in Bali, Indonesia: Qualitative Phenomenological Study Hidayat, Jufri; Huang, Xuan-Yi; Lin, Hung-Ru; Wei, Shiow-Jing; Chen, Miao-Yen; Pranata, Satriya
Makara Journal of Health Research Vol. 26, No. 1
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Background: Human immunodeficiency virus (HIV)-related stigma continues to be a serious problem for people living with HIV (PLWH). This study aimed to explore stigma experience among PLWH in Bali, Indonesia. Methods: This research was a qualitative descriptive phenomenological study. With the help of a local clinician–researcher and the staff of the United Nations Program on AIDS Commission, Bali, 10 participants were recruited by purposive sampling and participated in semi-structured interviews via WhatsApp online audio from April to December 2021. Data were analyzed using Colaizzi’s process. Results: The following three themes emerged: (1) experiencing discrimination, (2) getting stronger through stigma experiences, and (3) receiving support. Interviews revealed that PLWH in Bali experience stigma and discrimination across settings, including communities, families, friends, employers, and health care. Some participants could turn the pressure of stigma into a source of strength, making them psychologically and mentally strong. This phenomenon mostly happened when the patients had positive attitudes toward illness and good coping mechanisms. Conclusions: This study showed the importance of support from family, friends, and organizations in surviving stigma. For PLWH, having a sense of self-support and resilience and adaptive mechanisms also help ease the negative effects of stigma and discrimination.
Exercise Motivations, Barriers, and Preferences of Tahfiz Students: A Qualitative Study Ibrahim, Farah Wahida; Mat Ludin, Arimi Fitri; Marzuki, Nur Aqilah; Ishak, Ismarulyusda; Othman, Mohd Sham; Abdul Warif, Nor Malia; Md. Zahir, Mohd Zaharen; Yaacob, Muhamad Toriq
Makara Journal of Health Research Vol. 26, No. 1
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Background: In Malaysia, the increasing prevalence of physical inactivity is alarming. The effects of adopting a sedentary lifestyle have led to health problems such as coronary heart disease and type II diabetes mellitus, as well as increased mortality rates. Young adults, including tahfiz students, tend to be physically inactive due to much time spent sitting during lectures or studying. Therefore, an active lifestyle must be encouraged. This study aims to identify the factors that influence tahfiz students to exercise. Methods: Data from 12 male and 19 female students were collected through in-depth interviews, which were recorded and transcribed into text then subjected to thematic analysis. Results: Results show that the main motivations to exercise were body health and fitness, self-appearance, and sense of togetherness. The main themes for barriers were aversion to exercise time and commitment. In general, respondents preferred a moderate, 10–30 minute group sessions for 3–5 times per week. Conclusions: This study revealed five themes for motivations (body health and fitness, psychological wellbeing, appearance, physical support, and enforcement), and six themes for barriers to exercise (aversion to exercise, time, commitment, discomfort, no motivation, and the environment). These factors could be considered in exercise module development to improve students’ engagement.

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