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Farmasains : Jurnal Farmasi dan Ilmu Kesehatan
Published by Universitas Muhammadiyah Malang
ISSN : 20863373     EISSN : 2620987X     DOI : 10.22219
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Farmasains publishes articles that cover textual and fieldwork studies with various perspectives of pharmacy science including: Pharmaceutical Technology Pharmaceutical Chemistry Biology Pharmacy and Natural Products Pharmacology and Toxicology Clinical Pharmacy Community Pharmacy Pharmacoepidemiology Pharmacogenomic and Pharmacogenetic Pharmacoeconomic Health-related topics
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 170 Documents
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Phytochemical screening and determination of total phenolic and total flavonoid contents of pear peel extracts Patricia, Vinda Maharani; Saputri, Fauzia Ningrum
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol 4, No 2 (2019): November
Publisher : University of Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v4i2.10166

Abstract

The study was carried out to investigate the presence of different phytochemicals as well as to determine the total phenolic and flavonoid contents of green pear/european pear peels and yellow pear/asian pear peels. Phytochemical screening of the pear peels was carried out following standard protocols. Total phenolic content was determined by Folin-Ciocalteu method and total flavonoid contents was determined by Aluminum Chloride Colorimetric method, measured using n-hexane, etil acetate, and methanol. Phenolics, flavonoids, tannins, alkaloids, and saponins are present in green pear and yellow pear peels. The total phenol and flavonoid contents are highest in methanol extracts in which green pear peels have a higher concentration than yellow pear peels. In conclusion, the green and yellow pear peels are rich in phenolic compounds and have great potential as natural antioxidants. Therefore, the results of this research should be considered to provide the possibility for future developments of highly functional antioxidants.
The correlation of cough medicine advertisement in television on community self-medication in Krajan Sae Beji Village Junjero Batu City (Based on BPOM Head Regulation Number 8 in 2017) Titani, Mutiara; Hidayat, Rahmat; Hidayati, Ika Ratna
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol 4, No 2 (2019): November
Publisher : University of Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v4i2.12505

Abstract

Self-medication is an action treat by taking its own actions from assessing complaints and symptoms and drug selection. In doing self-medication, the community must have knowledge of the symptoms and drugs obtained from several sources, for example in television advertising. So this research’s goals is to determine the relationship of cough medicine advertisements on television to self-medication attitudes in Krajan Sae Hamlet, Beji Village, Junrejo Subdistrict, Batu City. This research is a descriptive study with  quantitative approach. Using instrument validated questionnaires. The sampling technique used is incidental sampling. The number of samples used refers to the Slovin’s formula with 97 respondents. To process this research the researcher use SPSS and Ms. Excel to get the correlation between cough medicine advertisements on television with public self-medication actions, influential indicators and linear regression results. The indicator that give influence of self-medication is indicator that is not misleading because it has the largest t count value of 2,360 with t table value 1,988 (df = 95). Regression  obtained by the results of simple linear regression equations namely Y = 7.618 + 0.303x. It means that, self-medication for cough medicines advertised on television will increase by 0.303 (b) units for each addition of one drug  unit. The results of the correlation study were analyzed using Ms. Excel obtained the results of r count 0.298 (N = 97, alpha = 0.05), with r table 0.195 (N = 100, alpha = 0.05). So that the value of r count > r table so Ho is rejected and Ha is accepted. It can be concluded that there is a relationship between cough medicine self-medication and television cough drug advertisement in Krajan Sae Hamlet, Beji Village, Junrejo Subdistrict, Batu City. 
Lavender aromatherapy inhalation to reduce menstrual pain in teenagers Azizah, Nurul
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol 4, No 2 (2019): November
Publisher : University of Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v4i2.12507

Abstract

One way to reduce the pain of dysmenorrhea with non-pharmacological therapy is lavender aromatherapy. The purpose of this research is to find out the picture of lavender aromatherapy inhalation in decreasing the intensity of primary dysmenorrhea pain. The research method uses quasi experiment with pre-post test non equivalent control group design. Analysis using independent sample T-test. The number of repondent 30 adolescents who experience dysmenorrhea pain on 1-2 days early menstruation according to inclusion criteria. pain measurement before and after lavender aromatherapy inhalation intervention using the VAS (Visual Analog Scale) pain scale then comparing the difference in the pretest and post test values.The results showed that prior to treatment, the intensity of dysmenorrhea pain was 8.53 and after being treated in the form of lavender aromatherapy inhalation there was a decrease in pain intensity with an average of 3.77. From the statistical results using the Independent Sample T Test, P values <0.002 with 95% C.I. -1,532 - (- 0.430). This shows that the decrease in pain intensity score of dysmenorrhea after inhalation of Lavender aromatherapy (Lavendula Augustifolia) is significant. Conclusion Most teenagers experience a decrease in pain after being given inhalation lavender aromatherapy. Suggestions for further researchers so that larger respondents so the results are more representative.
Knowledge of sunlight exposure toward obesity in geriatric Lorensia, Amelia; Suryadinata, Rivan Virlando; Fitrianingsih, Nurul
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol 5, No 1 (2020)
Publisher : University of Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v5i1.11454

Abstract

Indonesia gets good sun exposure every year. Sunlight is a major source of vitamin D., but studies show that tropical countries still have a high prevalence of vitamin D deficiency. Geriatrics and obesity are some of the factors that can lead to vitamin D deficiency. Lack of information and knowledge about the effects of vitamin D deficiency, concerns about skin cancer from sunburn, and some current trends that want white skin cause them to limit sun exposure. Based on the high prevalence of geriatric and obesity data in Indonesia and the decline of functional status in geriatrics, which is a person's ability to perform daily physical activity, thus limiting himself to outdoor physical activities to expose the sun. Researchers conducted research to see the knowledge of sun exposure. This study was conducted to analyze vitamin D deficiency risk factors by the cross-sectional method to 88 obesity geriatrics and 88 non-obesity geriatrics based on knowledge of sun exposure. Test the risk factor aspects of knowledge using the odds ratio. The result of the odds ratio test of the knowledge aspect is 0.725, so it can be concluded that good knowledge of sun exposure has the same risk in both groups of respondents (obesity and non-obesity).
Plant cyanogenic glycosides: an overview Hartanti, Dwi; Cahyani, Arinda Nur
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol 5, No 1 (2020)
Publisher : University of Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v5i1.10047

Abstract

The cyanogenic glycosides have consisted of α-hydroxy nitrile aglycone and a sugar moiety that producing hydrogen cyanide (HCN) during the hydrolysis process. This HCN-producing property underlines the toxicity of the plants commonly associated with these compounds in humans and animals. However, new evidence shows that the toxicity of these compounds is lower than those theoretically caused by the equivalent released HCN. In order to provide a deeper understanding of cyanogenic glycosides, an overview of these compounds is given in this article. It covers the chemistry, distribution, biosynthesis, toxicity, determination, as well as extraction and isolation of the compounds. 
The relationship of self-stigma with the quality of living people with HIV/AIDS (PLWHA) in WPA Turen District Kurniawanto, Dani; Sasono, Tri Nurhudi; Kumalasari, Galuh
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol 5, No 1 (2020)
Publisher : University of Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v5i1.12657

Abstract

Stigma is something that unacceptable or usually condescending and degrading. Stigma and discrimination cause inhibition of HIV/AIDS prevention and treatment in the community, thus impacting psychologically and decreasing the quality of life of PLWHA. To find out the relationship between self-stigma and the quality of life of people living with HIV/AIDS (PLWHA), a study in the AIDS Concerned Residents (ACR) District of Turen. It uses a correlational analytic design with a cross-sectional approach. The number of respondents is 22 PLWHA in Turen Concerned Residents (ACR), and methods of sampling in this study are using a purposive sampling technique. From 22 respondents, the result of self-stigma on PLWHA was low, with a percentage (54.5%) and the quality of life of PLWHA living in ACR Kec. Turn is excellent, with a percentage (54.5%). The results of statistical tests show that the value of p = 0.108 and the significance level of 0.05 also obtained p > 0.05, meaning that there is no significant relationship between self-stigma and the quality of life of PLWHA. This study shows that there is no significant relationship between self-stigma and the quality of life of PLWHA. With the existence of ACR, people and HIV-AIDS sufferers in Turen District have started to eliminate existing stigma and have a good quality of life.
Formulation and evaluation of hand sanitizer gel containing infused of binahong leaf (Anredera cordifolia) as antibacterial preparation Rahmasari, Dyah; Hendradi, Esti; Chasanah, Uswatun
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol 5, No 1 (2020)
Publisher : University of Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v5i1.13008

Abstract

Hand sanitizer gel is one of the alternative methods for hand hygiene when soap and water are not available. Binahong leaf (Anredera cordifolia) is a natural herb that has phenolic, flavonoids, saponins, and the steroid-terpenoids compound, which is potentially used as the active ingredient in the hand sanitizer gel. The primary purpose of this research was to determine the antibacterial potential and physicochemical properties of a hand-sanitizer gel containing binahong leaves’ infusion against Staphylococcus aureus. The efficacy of this formulation was tested against a bacterial strain using the disc diffusion method and determined by measuring the inhibition zone of each preparation. The testing of physicochemical properties includes the organoleptic test, pH, viscosity, and gel spreadability. The physicochemical characteristics of the gel showed excellent properties for all formulas. The antibacterial test showed that hand sanitizer gel containing an infusion of binahong’s leaves has an inhibition zone (6.02 mm; 6.24 mm; 6.55 mm), almost close to a positive control (9.15 mm). In conclusion, the formulated hand sanitizer gel possesses the antibacterial potential to inhibit S. aureus.
In vitro testing of emulgel with a combined extract of Sansevieria trifasciata Prain. and Curcuma longa Linn. against the Candida albicans Chasanah, Uswatun; Permatasari, Ayudya Rizky
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol 5, No 1 (2020)
Publisher : University of Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v5i1.13185

Abstract

Content of flavonoids in Sansevieria trifasciata Prain. and curcumonoids in Curcuma Longa Linn. can inhibit the growth of the fungi Candida albicans in the wound. An innovative formulation was made that form a combination of antifungal extracts S. trifasciata and C. longa in the form of emulgel, which is easy to absorb and can moisturize the skin. The purpose is to determine the effect of antifungal activity of emulgel preparations using S. trifasciata extract with a concentration of 0%; 5%; and 10%, and C. longa 10% against C. albicans. S. trifasciata and C. longa extracts are formulated into emulgel in three formulas, F1 (C. longa 10%); F2 (S. trifasciata 5%; C. Longa 10%); and F3 (S. trifasciata 10%; C. Longa 10%). Antifungal activity was tested using the diffusion well method. The results of antifungal activity research showed inhibition zone diameter, inhibitory activity, and effectiveness. There were no significant differences in formula 1, formula 2, formula 3, but there were significant differences with positive controls. Variation the concentration of S. trifasciata 5% and 10% has no significant effect on the inhibitory zone of the C. albicans, but the three emulgel of S. trifasciata and C. Longa extract had antifungal activity on the growth of C. albicans.
Benefit administration of vitamin B1, B6, and B12 on the depression symptom in hemodialysis patients Rizaldy Taslim Pinzon; Birgitta Lisbethiara Ardiani
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 4 No. 2 (2019)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v4i2.8919

Abstract

Chronic kidney disease (CKD) is a disease that causes a decrease in kidney function, which can be seen from GFR (Glomerulus Filtration Rate) value, which is less than 60 ml/minute/1.73 m2 in minimum three months. Depression is a psychological problem in a patient with chronic kidney disease undergoing hemodialysis. The previous study has shown that giving vitamin B combination can improve depression symptoms. To measure the benefit of vitamin B1, B6, B12 parenterally for depression symptoms in chronic kidney disease patients undergoing hemodialysis. This study used an experimental design (one group pre and post-test) in 117 patient that obtained using a consecutive sampling method. Depression score was measured by the HADS questionnaire before given vitamin B (pre-test) and after given vitamin B (post-test). Data were statistically analyzed using a licensed SPSS program with paired t-test/Non-Parametric Wilcoxon. The relationship between the history of the use of the antihypertensive, antidiabetic, folic acid drug, and depression scores were not showing significant results (p > 0.05). The relationship between administration of vitamins B1, B6, and B12 and the patient's depression score showed a decrease but not significant (p = 0.522). There was no significant difference after the administration of vitamin B1, B6, and B12 on the depression score of patients with chronic kidney disease undergoing hemodialysis at Bethesda and Panti Rapih Hospital in Yogyakarta.
Plant cyanogenic glycosides: an overview Dwi Hartanti; Arinda Nur Cahyani
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 5 No. 1 (2020)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v5i1.10047

Abstract

The cyanogenic glycosides have consisted of α-hydroxy nitrile aglycone and a sugar moiety that producing hydrogen cyanide (HCN) during the hydrolysis process. This HCN-producing property underlines the toxicity of the plants commonly associated with these compounds in humans and animals. However, new evidence shows that the toxicity of these compounds is lower than those theoretically caused by the equivalent released HCN. In order to provide a deeper understanding of cyanogenic glycosides, an overview of these compounds is given in this article. It covers the chemistry, distribution, biosynthesis, toxicity, determination, as well as extraction and isolation of the compounds. 

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