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Jurnal Natural
ISSN : 14118513     EISSN : 25414062     DOI : https://doi.org/10.24815/jn
Jurnal Natural (JN) aims to publish original research results and reviews on sciences and mathematics. Jurnal Natural (JN) encompasses a broad range of research topics in chemistry, pharmacy, biology, physics, mathematics, statistics, informatic and electronic.
Articles 457 Documents
Oral glucose tolerance assay of extract from Mangifera foetida l. and Pandanus amaryllifolius roxb. leaves RETNANINGTYAS, YUNI; CRISTIANTY, FRANSISKA MARIA; KRISTININGRUM, NIA; WARDANI, PRAMUDIA
Jurnal Natural Volume 24 Number 1, February 2024
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jn.v24i1.30982

Abstract

This study examines the potential antidiabetic activity of a combination of Mangifera foetida L. and Pandanus amaryllifolius Roxb. leaves. Mangifera leaves contain a compound called mangiferin, which acts as an antidiabetic and antioxidant. On the other hand, Pandanus leaves, are rich in terpenoids and steroids that also possess anti-diabetic effects. An Oral Glucose Tolerance Test (OGTT) was conducted on male mice of the Babl/c strain to assess the antidiabetic effects. The test involved administering a combination of ethanolic leaf extracts from Mangifera foetida L. and Pandanus amaryllifolius Roxb. in a 1:1 ratio. The study followed a pre-test design with a control group, comprising six treatment groups, each consisting of four male mice. The groups were described as follows: Group 1 was served as the normal group without any treatment. Groups II-IV received single extracts or combinations of extracts at doses of 62.5 mg/200g BW, 125 mg/200g BW, and 250 mg/200g BW. Group V acted as the positive control and was given oral glucose and glibenclamide at a dose of 0.09 mg/200g BW. Group VI was served as the negative control, receiving oral glucose and distilled water. The group that exhibited the highest percentage of decreased blood sugar levels was the one given oral glucose at a dose of 0.078g/20g BW of mice, along with the combination of Mangifera foetida L. and Pandanus amaryllifolius Roxb. leaves extract (1:1) at a dose of 35 mg/20g BW. This group demonstrated a decrease of 71.985 4.858 in blood glucose levels. The ANOVA analysis confirmed that the percentage decrease in blood sugar levels was significantly different from the positive control, indicating a higher effectiveness of the combination treatment in reducing blood glucose levels than the positive control.
Factors that influence the recovery of TB patients using Cox proportional hazard regression ZURNILA MARLI KESUMA; HIZIR SOFYAN; LATIFAH RAHAYU; WARDATUL JANNAH
Jurnal Natural Volume 21 Number 1, February 2021
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jn.v21i1.18717

Abstract

Tuberculosis (TB) is an infectious disease which is one of the biggest health problems in the world, including Indonesia. The government, through the National Tuberculosis Control program, has made various efforts to control tuberculosis. However, this problem was exacerbated by the dramatic increase in the incidence of tuberculosis. This study aimed to determine the Cox proportional hazard regression model and the factors that affect the cure rate of TB patients. We used medical record data for inpatient TB patients for the period July-December 2017 at dr. Zainoel Abidin Hospital. The results showed that with α = 0.1, the factors that influenced the recovery of TB patients were the type of cough, the symptoms of bloody cough and symptoms of sweating at night.  There were 33.93% of patients who did not work. This category included students, domestic helpers, and those who did not work until they suffered from tuberculosis and were treated at dr. Zainoel Abidin Hospital. The hazard ratio (failure ratio) showed that the tendency or cure rate for TB patients who did not experience cough symptoms was 70% greater than patients who experienced phlegm cough symptoms. The cure rate for TB patients who experienced coughing up blood symptoms was 53% greater than patients without these symptoms. The cure rate for TB patients who experienced  symptoms of sweating at night was 54% greater than patients who did not sweat at night.
ANALYSIS OF SHALLOW SUBSURFACE STRUCTURE AT GEOTHERMAL AREA OF IE JUE USING RESISTIVITY METHOD Syafrizal Idris; Muhammad Syukri; Muhammad Syukri Surbakti; Marwan .; Muchlis .; Ibnu Rusydy; Nurul Aflah
Jurnal Natural Volume 18, Number 1, February 2018
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jn.v18i1.9676

Abstract

It has been conducted a geo-electrical resistivity survey at geothermal area of Ie Jue, Aceh Besar.  The survey aims to measure resistivity value in the area. It is expected that the values of resistivity will image the subsurface structure in the area. In addition geological features in the area are shown after we process it. The data acquisition in this study was acquired using a SuperSting R8/IP resistivitymeter and its data processing using EarthImager 2D software to get the image of resistivity pseudosection. The two lines of measurement crossed the surface geothermal manifestation. Each line has 330 m in length, and 56 electrodes with electrode space of 6 m. The result of resistivity pseudosection model interpreted based on geological condition and observation in the area. Resistivity pseudosection model shows the study is water-saturated (64.0 Ωm) to a depth of ±65 m and a highly conductive zone (0.6-3.5 Ωm) with a thickness of 30-50 m. This conductive layers below the embodied surface at a distance of 158-160 m on the IJ-Y1 line and at a range of 130-185 m on the IJ-Y2 line. This conductive zone is indicated as a weak zone where geothermal fluids are transported to the surface.Keywords: Geothermal, Ie Jue, geo-electrical resistivity survey, resistivityREFERENCES          Bennet, J.D., Bridge, D.McC., Cameron, N.., Djunuddin, A., Ghazali, S.A., Jeffrey, D.H., Kartawa, W., Rock, M.N.S., Thomson, S.J., Whandoyo, R., 1981. PetaGeologiLembar Banda Aceh, Sumatera, Puslitbang Geologi. Bandung.Syukri, M., Saad, R., Nordiana, M., Azwin, I. 2014. Preliminary Study of Sumatera Fault Using 2-D Resistivity Imaging Method. Electronic Journal of Geotechnical Engineering, 19.Knödel, K., Lange, G., Voigt, H.J., 2007. Environmental geology: Handbook of field methods and case studies: Springer Science Business Media.Telford, W. M., Geldart, L. P., Sheriff, R. E. 1990. Applied Geophysics Second Edition, Cambridge University Press, USAMarwan, M., Rusydy, I., Nugraha, G.S. and Asrillah, A., 2014. Study of Seulawah Agam’s Geothermal Source Using Gravity Method. Jurnal Natural, 14(2)Asrillah, A., Marwan, M., Rusydy, I. and Nugraha, G.S., 2014. Application of Magnetics Method to Mapping the Geothermal Source at Seulawah Agam Area. Jurnal Natural, 14(2).Ismail, N.,Ramadhan, S., 2013. Karakterisasi Struktur Dangkal pada Lapangan Panas Bumi Seulawah Agam Menggunakan Metode Very Low Frequency (VLF). Prosiding Semirata FMIPA Universitas Lampung. Lampung, Indonesia.
KAJIAN STATISTIK SEISMISITAS KAWASAN SUMATERA Warni Asnita; Didik Sugiyanto; Ibnu Rusydy
Jurnal Natural Volume 16, Number 2, September 2016
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jn.v16i2.4917

Abstract

The research was conducted in order to identify the distribution of seismicity, repeated periods of earthquakes and the probability of earthquake in Sumatra using Likelihood Maximum methods. Earthquake data from the ISC and USGS catalogue were used. Earthquake data from 1914-2014 (100 year span)  with magnitude of (M)≥5 SR and depth (h)≤100 km that is located at 60LS – 100LU and 920BT – 1080BT. The latitude and longitude coordinates were divided into 21 regions. The results showed distribution of seismicity in Sumatran as much as 3634 events of earthquake during the 100 last years. The distribution of seismicity in Sumatra is quite high. From data shown, there was value a, which is between 4.81 - 9.94 and value b which is between 0.54 - 1.32.  This condition indicated an index value of M≥5 SR, which is between 0.006 - 0.076 and repeated periods between 13 - 175 years with the probability of earthquake M≥5 SR between 5.6% - 99.9% for T (time) = 10, 50 and 100 years.
Influence of monomer concentration on the morphology, contact angle, water uptake, and antibacterial activity of grafted cellulose obtained from peel durian ROSLIANA LUBIS; SAISA SAISA
Jurnal Natural Volume 22 Number 1, February 2022
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jn.v22i1.23865

Abstract

The objective of the current study is to evaluate and determine the effect of monomer concentration of ClAETA on the grafting copolymerization of oxidized cellulose which isolated from peel durian. Four concentrations of ClAETA were used in this study, e.g., 40, 50, 60, and 70%. Several analyses were performed to determine the material characteristic, e.g., degree of grafting, FT-IR, surface morphology, contact angle, degree of swelling, and antibacterial activity. The result showed, monomer concetration plays a significant role to the physical and surface morphology of DAC-ClAETA. The degree of grafting of ClAETA was found in the range of 15-31%, and at the concentration of 50% the grafted oxidized cellulose has 30.4% of degree of grafting. SEM images showed the pore volume has linear correlation to the monomer concetration, it increased the surface roughness. Also, the contact angle confirmed the hydrophilicity and degree of swelling of grafted oxidized cellulose was increase that linear to ClAETA concentration. DAC-g- ClAETA was found antibacterial active against S. aureus, S. epidermis, and C. albicans than DAC.
PHYLOGENETIC ANALYSIS OF 16S rRNA GENE FRAGMENT OF ANTIBIOTIC-PRODUCING PLS 76 ISOLATE Mulia Aria Suzanni; Amelya Yolanda; Nurdin Saidi; Febriani Febriani; Teuku Mohamad Iqbalsyah
Jurnal Natural Volume 18, Number 3, October 2018
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jn.v18i3.11152

Abstract

Exploitation of extremophiles as novel bioactive compounds sources has been increasing. The aim of this study was to evaluate the activity and the class of antibiotic produced by a thermo-halophilic isolate PLS 76, as well as to identify the genotype of the isolate. The activity was determined by a disc diffusion method, while the antibiotic class was determined qualitatively by chemical reactions using ninhydrin, iodine vapour and potassium iodine. The genotype was determined by sequencing the 16S rRNA gene fragment and the phylogenetic tree from the sequence data. The results showed that PLS 76 was a Gram-negative bacterium and able to produce polypeptide antibiotic, which showed a slight activity on E. coli and S. aureus. Sequence alignment of the 16S rRNA gene fragment showed that PLS 76 was most related to Geobacillus kaustophilus. These results may be used to utilise the isolated for further antibiotic study.
Study of white frangipani flower and bitter grape stem ethanol extract combination on antibacterial and antioxidant activities KRISHNA PURNAWAN CANDRA; WIJAYANTI KUSUMA WARDHANI; ANTON RAHMADI; MIFTAKHUR ROHMAH; YULIANI YULIANI
Jurnal Natural Volume 20 Number 3, October 2020
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jn.v20i3.17175

Abstract

Frangipani flower (Plumeria acuminata) and bitter grape (Tinospora crispa L. Miers) stem extract alone shows antimicrobial and antioxidant activities. However, there is a limited report about the actions from the combination of both extracts. Combinations of ethanol extract of white frangipani flower (EFF) and ethanol extract of the bitter grape stem (EBS), each of 0, 1, 2, and 3% were tested for inhibition against Staphylococcus aureus growth and DPPH (1,1-diphenyl,2-picrylhydrazyl) free radicals. A yield of 3.17 and 2.62 g of EFF and EBS, respectively, were resulted from 100 g of dried powdered of the white frangipani flower and bitter grape stem using 200 mL of absolute ethanol. The antimicrobial test was assayed using a 10% stock solution of extract diluted in water. The combination of EFF and EBS showed a synergistic effect on antimicrobial activity, but it proved an antagonistic effect on antioxidant activity. The combination of EFF 3% and EBS 3% showed the highest inhibition index on the S. aureus growth , i.e. 2.02±0.06, which is higher than the inhibition index of Amoxycillin 2%, i.e. 1.85±0.09. The highest antioxidant activity showed by 1% EFF alone (57.5 ± 0.60%), while the lowest was from the combination of EFF 1% and EBS 3% (23.4±0.30%).  
DETERMINATION OF RADON CONCENTRATIONS IN DWELLING IN ACEH Wahyudi Wahyudi; Dadong Iskandar; Rini Safitri; Kusdiana Kusdiana
Jurnal Natural Volume 17, Number 2, September 2017
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jn.v17i2.8154

Abstract

Abstract. Determination of radon concentrations in dwelling in Aceh region by using a passive method has been conducted. In this research, area considered was divided into several sections called grid. Each grid represents an area of 60 km x 60 km in which, depend on public response, 6-10 passive radon monitors were installed. The number of passive radon monitors installed in Aceh is 200 units, and they can be taken back as many as 191 units or 95.50 %. The passive radon monitors have stayed in dwelling for 3-4 months and after period of the exposure, those radon monitors were taken back and brought to laboratory for further process, and then the track were read and the radon concentrations were calculated. Furthermore, data of radon concentration in dwelling and GPS location were put into MapInfo Software v.10.5 to create a map of radon concentration. The results of the analysis of the radon concentration in dwelling in Aceh demonstrate that the concentrations are in the range of 3.32 ± 0.23 Bq/m3 up to 68.30 ± 4.83 Bq/m3. This result was lower than the radon reference level determined by UNSCEAR, which was 300 Bq/m3. The data are useful in the regional extension and development plans, as well as the basis for health policy analysis due to the existence of radon in Indonesia. Furthermore, these data will become the contribution of Indonesia in the international world through UNSCEAR, IAEA and WHO. The data obtained can be used as partial data in creating a map of radon concentration in residents’ houses in Aceh, as a part of the map of radon concentration in Indonesia. Keywords: radon concentration, dwelling, Aceh, passive methodREFERENSI UNSCEAR, 1996, Natural Radiation Exposures, Forty Fifth Session, VienaIAEA, 2005, Radiation, People and the Environment, Viena.Bunawas, Emlinarti, M. Affandi, 1996, Penentuan laju lepasan radon dari bahan bangunan menggunakan metode pasip dengan metode jejak nuklir, Prosiding PPIKRL, PSPKR-BATAN, 20-21 Agustus 1996, pp. 16-21.Sutarman, L. Nirwani, Emlinarti dan A. Warsona, 2005, Penentuan konsentrasi gas radon dan thoron menggunakan detektor film LR-115 di DKI Jakarta dan sekitarnya, Prosiding PPI–PDIPTN P3TM-BATAN, Jogjakarta, p. 212-221.M. Affandi, D. Iskandar, dan Bunawas, 1996, Radon di Kompleks Perumahan BATAN, Presiding PIKRL, PSPKR-BATAN, p. 262-265Wahyudi, Kusdiana and D. Iskandar, 2016, Mapping of Indoor Radon Concentration in Houses Located in South Sulawesi Province, 2nd International Conference on the SERIR2 14th Biennial Conference of the SPERA, Bali, CTRSM-BATAN, p. 35-38.E. Pudjadi, Wahyudi, A. Warsona and Syarbaini, 2016, Measurement of Indoor Radon-Thoron Concentration in  Dwellings of Bali Island, Indonesia, 2nd International Conference on the SERIR2 14th Biennial Conference of the SPERA, Bali, CTRSM-BATAN, p. 186-192.M.H.Magalhães, et al., 2003. Radon-222 in Brazil: an outline of indoor and outdoor measurements. Journal of Environmental Radioactivity, 67(2), pp.131–143.F.S. Al-Saleh, 2007. Measurements of indoor gamma radiation and radon concentrations in dwellings of Riyadh city, Saudi Arabia. Applied Radiation and Isotopes, 65(7), pp.843–848.
SYNTHESIS AND CHARACTERIZATION OF HEMATITE (Fe2O3) EXTRACTED FROM IRON ORE BY PRECIPITATION METHOD Andia Andia; Adi Rahwanto; Zulkarnanin Jalil
Jurnal Natural Volume 16, Number 1, March 2016
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jn.v16i1.4361

Abstract

Indonesia has a lot of mining material of iron ore that could be used for various purposes in the steel industry or for other. This research, has synthesized and characterization of hematite from local iron ore from Lhoong area by precipitation mechanism. The iron ore powder was magnetic separation with magnet then mixed with HCl and NH4OH. Then, it was dried at temperature of 150 ºC and calcinated at 500º C for 2 hours. Characterizations were perfomed using X-ray Diffraction (XRD) and X-ray Fluorescence (XRF). As the results, it was found that the magnetic separation iron ore showed the composition of Fe2O3 (95.99%), SiO2 (2.10%). Then, by precipitation mechanism, the composition of Fe2O3 found around 96.58%. Next, the synthesis result are characterized with XRD show that the main phase is dominan in iron ore of Lhoong is hematit (Fe2O3). Scherrer calculations showed that precipitation mechanism to reducing grain size, the process of magnetic separation (58.009 µm) and the precipitation mechanism (20.950 µm.)
Assessing soil bacterial community response to organophosphate pesticides in agricultural field of Yogyakarta, Java, Indonesia ANNA RAKHMAWATI; BERNADETTA OCTAVIA; SUHARTINI SUHARTINI; TIEN AMINATUN
Jurnal Natural Volume 23 Number 3, October 2023
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jn.v23i3.31263

Abstract

Soil contamination by pesticides is one of the world’s most pressing environmental issues. The widespread use of Organophosphate pesticides (OPPs) in agriculture has led to biological diversity changes. The indigenous bacterial community played significant roles in the remediation of soil contaminated with OPPs. This study examines the overall bacterial community composition of three agricultural fields in Yogyakarta, Java, Indonesia, that were exposed to OPPs. The agricultural field was divided into zones near the beach, residential, and mountainous. Sequencing 16S rRNA amplicon fragments used to analyze the soil bacterial community. It was discovered that Proteobacteria, Actinobacteria, and Firmicutes comprised the majority of the bacterial community. In addition, the samples contain a high relative abundance of Bacillus, Bradyrhizobium, Chryseobacterium, Cystobacter, Microvirga, and Burkholderia. The high alpha diversity indexes suggest that the agricultural soil microbiome provides important ecological services and may harbor a wide variety of bacteria and genes with biotechnological applications. The physicochemical soil characteristics are also correlated with the bacterial community structure. The findings can be used to develop bioremediation strategies that employ native microbes to clean and restore agricultural soil contaminated with OPPs.