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Madani: Multidisciplinary Scientific Journal
Published by Yayasan Daarul Huda Kruengmane
ISSN : -     EISSN : 29866340     DOI : https://doi.org/10.5281/zenodo.8360194
Core Subject : Religion, Humanities, Health, Science, Education, Agriculture, Art, Social, Engineering,
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Chemical Engineering, Chemistry & Bioengineering Civil Engineering, Building, Construction & Architecture Computer Science & IT Education Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Physics Public Health Social Sciences Other
Madani: Jurnal Ilmiah Multidisiplin diterbitkan oleh Yayasan Daarul Huda Kruengmane. Madani: Jurnal Ilmiah Multidisiplin menerbitkan artikel bidang multidisiplin, mencakupi bidang Pendidikan, Hukum, Ekonomi, Agama, Pendidikan, Kesehatan, Teknik, Kebijakan Publik, Pariwisata, Sosial dan Politik, Budaya dan Seni.
Arjuna Subject : Umum - Umum
Articles 37 Documents
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Search results for , issue "Vol 3, No 3 (2025): April 2025" : 37 Documents clear
Kimia Medisinal dan Perannya Dalam Pengembangan Terapi Personalisasi M, Maesaroh; Amin, Saeful
Madani: Jurnal Ilmiah Multidisiplin Vol 3, No 3 (2025): April 2025
Publisher : Penerbit Yayasan Daarul Huda Kruengmane

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.15187886

Abstract

Personalized therapy is a treatment approach that considers genetic, environmental, and lifestyle variations of each individual to optimize the effectiveness and safety of therapy. This study aims to analyze the role of medicinal chemistry in the development of personalized therapy through the perspective of rational design of drug molecules, structural modification, and optimization of pharmacokinetic-pharmacodynamic properties. The method used is a systematic literature review with the PRISMA approach to scientific publications in 2013-2023 that focus on the integration of medicinal chemistry with pharmacogenomics and personalized therapy. The results of the study showed that medicinal chemistry plays an important role in four main areas: (1) drug design based on specific genetic targets with high selectivity (76% of publications); (2) development of prodrugs and drug delivery systems that are responsive to individual biomarkers (63% of publications); (3) optimization of pharmacokinetics based on genetic variations of drug metabolizing enzymes (58% of publications); and (4) development of molecular probes for companion diagnostics (52% of publications). Further analysis identified the development trends of personalized therapy including multi-target drug design based on patient molecular profiles and big data-based medicinal chemistry strategies. The main challenges identified include the complexity of molecular modification to achieve pharmacokinetic profiles that match specific genetic subtypes and the limitations of experimental models that represent individual heterogeneity. In conclusion, medicinal chemistry plays a fundamental role in realizing the concept of personalized therapy through the design and optimization of drug molecules that match individual patient characteristics. Further research is needed for the development of medicinal chemistry methodologies integrated with omics technology and artificial intelligence to accelerate the translation of the concept of personalized therapy into real clinical applications in Indonesia.
Strategi Orang Tua Dalam Perkembangan Anak Usia Dini di Era Metaverse Saflitha, Widya; Sehati, Rindu; Wahyuni, Sri; Siregar, Arinil Haq
Madani: Jurnal Ilmiah Multidisiplin Vol 3, No 3 (2025): April 2025
Publisher : Penerbit Yayasan Daarul Huda Kruengmane

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.15162763

Abstract

This study aims to examine parents' strategies in integrating metaverse in early childhood development, considering the significant changes in the way children learn and interact in the fast-paced digital era. This study explores how metaverse, as a platform that enables immersive and interactive learning and socialization experiences, is used by parents to support their children's cognitive, social, and emotional development. Through in-depth qualitative analysis, this study uses a descriptive approach to systematically describe and analyze this phenomenon, with data collected through observation, documentation, and in-depth interviews with parents. The data analysis technique follows the Miles, Huberman, and Saldana model, with data validity checks through source triangulation. The results of the study are expected to provide valuable insights into how parents can utilize metaverse for effective parenting, as well as support the formation of policies and practices that ensure the safe and inclusive use of technology in early childhood care.
Sistem Bilangan Babilonia dan Pengaruhnya Terhadap Ilmu Pengetahuan Moder Prabawa, Ivan; Sagala, Rifal Zingiber
Madani: Jurnal Ilmiah Multidisiplin Vol 3, No 3 (2025): April 2025
Publisher : Penerbit Yayasan Daarul Huda Kruengmane

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.15206034

Abstract

Sistem matematika Babilonia, terutama yang berkaitan dengan bilangan, aljabar, geometri, dan astronomi, adalah salah satu yang paling tua dan berdampak besar pada kemajuan ilmu pengetahuan. Studi ini menyelidiki sistem bilangan seksagesimal yang digunakan oleh orang-orang Babilonia dan aplikasinya dalam berbagai bidang ilmu. Sistem bilangan ini memungkinkan perhitungan yang lebih kompleks dan presisi, menurut metode deskriptif kualitatif yang didasarkan pada studi pustaka. Hingga saat ini, sistem waktu dan pengukuran sudut masih digunakan. Selain itu, orang-orang Babilonia juga memahami teori tripel Pythagoras, membuat persamaan kuadrat menggunakan teknik numerik, dan membuat tabel astronomi yang dapat memprediksi gerhana dan pergerakan planet. Seperti yang ditunjukkan oleh penelitian ini, warisan matematis Babilonia berkontribusi pada perkembangan masyarakat Yunani dan Islam serta memberikan dasar untuk matematika modern, yang digunakan dalam berbagai disiplin ilmu.
Penerapan Nilai Adaptif Budaya Lokal Pada Pembelajaran PAI Di Sekolah Dasar Negeri Kota Bukittinggi Gustina, Elvy; Hendri, Novi
Madani: Jurnal Ilmiah Multidisiplin Vol 3, No 3 (2025): April 2025
Publisher : Penerbit Yayasan Daarul Huda Kruengmane

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.15181557

Abstract

This research aims to explore the application of adaptive value of local culture in Islamic Islamic Religious Education (PAI) learning in public primary schools in Bukittinggi City. Bukittinggi. The method used is a qualitative approach with data data collection techniques through interviews, observation, and documentation. The results The results showed that the integration of local cultural values into the PAI curriculum not only improves students' understanding of the subject matter, but also strengthens their religious character rooted in local traditions. local traditions. The integration of local values, such as gotong royong, togetherness, and respect for the environment, in the PAI curriculum can increase students' motivation to learn. for the environment, in the PAI curriculum can increase students' learning motivation as well as their understanding of religious teachings. and their understanding of religious teachings. Through experiential learning methods, such as experiential learning methods, such as visits to cultural sites and direct engagement with the community, students not only learn theory but also with the community, students not only learn theory but also experience the application of these values in their daily lives. feel the application of these values in their daily lives. However, challenges such as limited resources and lack of training for teachers in integrating local wisdom into learning still need to be addressed. teachers in integrating local wisdom into learning still need to be addressed so that the application of these values can run optimally and sustainably. With the support of the community and related parties, it is hoped that local wisdom-based education can create a sustainable based education can create a generation that is not only academically smart but also has a strong character. academically but also have a strong character and are proud of their heritage. heritage. Implications 
Bahasa Indonesia Dalam Dunia Pendidikan dan Tantangan Dalam Penggunaannya Secara Akademik Nasution, Abidah Ramadhani; Pulungan, Hendra Kurnia; Marsyah, Aralia Putri; Dewi, Artika Sardiana; Sari, Defi Mawar; Pangaribuan, Devy J.R; Manurung, Elisabet Magdalena; Sinaga, Husna Khoiri; Harefa, Rili Angelica; Hutasoit, Sartika Br
Madani: Jurnal Ilmiah Multidisiplin Vol 3, No 3 (2025): April 2025
Publisher : Penerbit Yayasan Daarul Huda Kruengmane

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.15138237

Abstract

This article examines the role of the Indonesian language in the national education context and analyzes various challenges in its use as an academic language. Through a descriptive qualitative approach by interviewing three language and education experts, this research identifies several main challenges such as limitations in technical vocabulary, foreign language influence, and gaps between standard Indonesian and everyday language. The results show that systematic efforts are needed to strengthen the position of Indonesian as a scientific language, including standardization of academic terms, development of quality teaching materials, and improvement of scientific writing skills among academics. In conclusion, strengthening Indonesian in the academic domain requires collaboration between language institutions, educational institutions, and the academic community to ensure its sustainability as a language of science in the era of globalization.
Strategi Manajemen Sarana dan Prasarana Untuk Meningkatkan Minat Belajar Siswa I MTSS SKB 3 Menteri Pembangunan Lidah Tanah Lubis, Arif Abdul Gani; Siahaan, Amiruddin; Tarigan, Mardinal
Madani: Jurnal Ilmiah Multidisiplin Vol 3, No 3 (2025): April 2025
Publisher : Penerbit Yayasan Daarul Huda Kruengmane

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.15235406

Abstract

The research entitled "Facilities and Infrastructure Management Strategies to Increase Students' Interest in Learning at MTSS SKB 3, Minister for Development of Tongue Tanah" aims to analyze facilities and infrastructure management strategies in order to increase students' interest in learning at MTSS SKB 3, Minister for Development of Tongue Tanah. Interest in learning is an important factor in the success of the educational process, and adequate facilities and infrastructure can play a big role in encouraging this interest. This research uses a qualitative descriptive approach with data collection techniques through interviews, observation and documentation. The research results show that the management of facilities and infrastructure at MTSS SKB 3 Ministers has been managed well, but there are still several challenges in meeting optimal facility needs. The strategies implemented include improving more varied learning facilities, routine maintenance of existing facilities, as well as optimizing the use of classrooms and laboratories for teaching and learning activities. This improvement in facilities and infrastructure has been proven to increase students' interest in learning, which is reflected in their activity during the learning process, both individually and in groups. This research suggests that the management of Islamic education at MTSS SKB 3 Minister of Development of Lidah Tanah continues to innovate in managing educational facilities and increase participation of all school elements to achieve optimal educational goals.
Strategi Dakwah Pengurus Masjid Dalam Meningkatkan Shalat Subuh Berjamaah di Masjid Al-Hidayah Plaju Tangga Takat Palembang Kadnezar, Niven; Ariadi, Purmansyah; R, Rulitawati
Madani: Jurnal Ilmiah Multidisiplin Vol 3, No 3 (2025): April 2025
Publisher : Penerbit Yayasan Daarul Huda Kruengmane

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.115190095

Abstract

This research aims to explore and analyze the da'wah strategies implemented by the management of Al-Hidayah Mosque in encouraging greater participation in congregational Fajr (Subuh) prayer. The declining attendance at Fajr prayer has become a significant concern, considering the high virtue and importance of this prayer in Islam. This study employs a qualitative descriptive method with a case study approach. Data were collected through observation, in-depth interviews with mosque administrators and congregants, as well as documentation. The findings indicate that the mosque management applies several da'wah strategies, including personal engagement with the community, regular Islamic lectures after Fajr prayer, motivational sermons, and the use of social media to disseminate mosque activities. These strategies have shown effectiveness in increasing awareness and participation among worshippers, although some challenges remain, such as individual lack of awareness and busy daily routines. This research is expected to contribute to the development of more effective mosque-based da'wah efforts that directly address community needs.
Analisis Dampak Sinetron “Jangan Bercerai Bunda” Terhadap Pembentukan Moralitas Publik Novita, Zahra Ersyah; Az Zahra, Shabrina Najla; Desrina, Rania Adriane; Ramadhanti, Shaila Azalea; Manurung, Abraham Hadonganan; Rahman, Hafizh Aulia; Marpaung, Haezer Josua Tio; Fauziyyah, Laila; Febriza, Muhammad Dyo; Sinulingga, Rizki Hagina
Madani: Jurnal Ilmiah Multidisiplin Vol 3, No 3 (2025): April 2025
Publisher : Penerbit Yayasan Daarul Huda Kruengmane

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.15210544

Abstract

This study aims to analyze the impact of the television drama “Jangan Bercerai Bunda”, specifically episodes 491, 511, and 345, on the formation of public morality. These particular episodes were selected due to their portrayal of complex domestic conflicts, intense emotional dynamics, and varied representations of moral values. Using a qualitative approach through content analysis and focused interviews, this research explores how certain scenes influence viewers’ perceptions of values such as loyalty, family responsibility, gender roles, and conflict resolution. The findings indicate that the drama plays a dual role: it can deliver positive moral messages about the importance of communication and family resilience, yet it may also shape misleading perceptions if conflicts are portrayed excessively or unrealistically. In conclusion, television dramas, as a form of popular media, significantly contribute to the construction of public morality and should be critically evaluated by both audiences and content creators.
Sebaran Pertumbuhan Alami Matoa (Pometia Pinnata) Berdasarkan Ketinggian Tempat di Kelompok Hutan Desa Badaro Kecamatan Modayag Kabupaten Bolaang Mongondow Timur Amon, Hendra; Rempas, Robby DJ
Madani: Jurnal Ilmiah Multidisiplin Vol 3, No 3 (2025): April 2025
Publisher : Penerbit Yayasan Daarul Huda Kruengmane

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.15186284

Abstract

The purpose of this study was to determine the distribution of natural growth at each growth level of matoa (Pometia pinnata) based on altitude in the forest group of Badaro Village, Modayag District, East Bolaang Mongondow Regency. The method used in this study is the survey method, while data collection uses the plot sampling method technique in the research area. The results of the study showed that in the Badaro Village Forest Group, natural stands of Pometia pinnata were spread from an altitude of 300 - 700 m above sea level. The largest number was in the sapling phase with 15 individuals, while the smallest number was in the tree phase with 6 individuals. The number of Pometia pinnata individuals in the seedling phase was 2 individuals at an altitude of 300 m above sea level, 3 individuals at an altitude of 400 m above sea level, 2 individuals at an altitude of 500 m above sea level, 2 individuals at an altitude of 600 m above sea level, and 1 individual at an altitude of 700 m above sea level. The number of Pometia pinnata individuals in the sapling phase was 1 individual at an altitude of 300 m above sea level, 4 individuals at an altitude of 400 m above sea level, 4 individuals at an altitude of 500 m above sea level, 2 individuals at an altitude of 600 m above sea level, and 4 individuals at an altitude of 700 m above sea level. The number of Pometia pinnata individuals in the pole phase was 2 individuals at an altitude of 300 m above sea level, 1 individual at an altitude of 400 m above sea level, 1 individual at an altitude of 500 m above sea level, 1 individual at an altitude of 600 m above sea level, and 2 individuals at an altitude of 700 m above sea level. Meanwhile, the number of Pometia pinnata individuals in the tree phase is 1 individual at an altitude of 300 meters above sea level, 2 individuals at an altitude of 400 meters above sea level, 1 individual at an altitude of 500 meters above sea level, 1 individual at an altitude of 600 meters above sea level, and 1 individual at an altitude of 700 meters above sea level. The distribution of natural growth of matoa (Pometia pinnata) at each growth phase based on altitude is the same or even at each altitude, but the higher the location, the fewer individuals are found.
Strategi Pengelolaan Panti Asuhan dalam meningkatkan Kesejahteraan Anak Asuh di Asrama Sahabat Yatim Medan Aksara N, Nurmayani; Haliza, Putri Yusra; Sarah, Auta Shintha; Faradhilah, Anatasia
Madani: Jurnal Ilmiah Multidisiplin Vol 3, No 3 (2025): April 2025
Publisher : Penerbit Yayasan Daarul Huda Kruengmane

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.15145439

Abstract

A good and correct orphan management system greatly affects the fate and future of orphans. The welfare of orphans is not only measured physically, but also mentally and spiritually. This study aims to understand the strategies, programs and challenges faced by the Sahabat Yatim Medan Aksara Orphanage and then provide solutions to any challenges faced. The research method used is a qualitative approach method by conducting interviews with caregivers, foster children, and management staff. Direct observation was conducted to see how the rules are applied, the availability of supporting facilities, the physical and psychological well-being of foster children, and the relationship between foster children and caregivers. The results showed that Sahabat Yatim Medan Aksara Orphanage has implemented rules, provided facilities for education and daily needs but still faced several challenges. Overall, the quality of life of foster children has been improved physically, mentally, and spiritually through good management and a comprehensive welfare program.

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