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Journal of Pharmaceutical and Sciences.
Published by Universitas Tjut Nyak Dhien
ISSN : -     EISSN : 26563088     DOI : https://doi.org/10.36490/journal-jps.com
Core Subject : Health, Science, Agriculture, Engineering,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health
Journal of Pharmaceutical and Sciences (JPS) with e-ISSN: 2656-3088 is a scholarly peer-reviewed open access journal related to Pharmaceutics, Pharmacology, biotechnology, Pharmacognosy & Phytochemistry, Pharmaceutical Chemistry, Pharmaceutical Biotechnology, Pharmacy practice, Pharmacogenomics, Medicinal Chemistry, Molecular Pharmacology, Novel drug delivery system, Nanotechnology, Analytical Chemistry, Organic Chemistry, Natural Chemistry, Polymer Sciences, Clinical Pharmacy, pharmaceutical management, pharmacoeconomics, pharmacoepidemiology, clinical pharmacy, community pharmacy, social pharmacy, pharmaceutical marketing, government policies related to pharmacy, pharmaceutical care, Medical Biotechnology, Biochemistry, food chemistry, health and applied sciences relevant to the field of pharmacy. Journal of Pharmaceutical and Sciences (JPS) accepts manuscripts in Indonesian Language (Bahasa Indonesia) with titles and abstracts in bilingual, both Indonesian and English. We accept article manuscripts in the form of original research, literature reviews, and systematic reviews. We do not accept articles in the form of case reports
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 11 Documents
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Search results for , issue "JPS Volume 7 Nomor 2 (2024)" : 11 Documents clear
Formulasi sabun mandi esensial minyak nilam dengan pewarna kopigmentasi biji kesumba keling (Bixa orellana L.) dengan angkak merah Indriana , Meutia; Sari, Nurmala; Julianty , Siti Muliani; Muzakkir, Muzakkir; Febriani , Yessi; Nurrahman, Taufik; Salman, Salman
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 2 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i2.342

Abstract

Background; The skin is the outermost layer of the body that serves as a protective barrier against exposure to sunlight and is also where sweat is produced. Sweat can make the skin appear dull and sticky. Soap is a cosmetic product that is used for body cleansing. Annatto and red mold rice are used as natural colorants formulated in soap preparations, where the color produced by annatto and red mold rice is not stable. Therefore, a copigmentation method is needed to stabilize the colorant annatto with red mold rice. Method; This research use an experimental approach that initially involves the extraction of annatto seeds and red mold rice using 96% ethanol. Subsequently, the extracted compounds are formulated into soap preparations with variations in ratios of 1:1, 1:2, 2:1, and 2:2. To evaluate the quality of the soap preparations, various tests have been conducted, including homogeneity testing, pH testing, foam height testing, water content testing, and irritation testing. Result; The results showed that the copigmentation of annatto seeds with red mold rice in the form of ethanol extract could be formulated into a soap dosage form at a ratio of 2:1 (F4) is the best preparation, is a homogeneous preparation, has a pH of 9.4 , has a foam height of 8.3 cm, has a water content of 6.25%. All copigmented soap with ethanol extract of annatto seeds with red mold rice does not irritate the skin of the hands.
Literature review: faktor-faktor yang berhubungan dengan health-seeking behavior dan quality of life pada pasien penderita asma Sulistiawati, Sulistiawati; Hilmi , Indah Laily
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 2 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i2.368

Abstract

Background: Asthma affects approximately 335 million people worldwide and is the 14th most common disease globally in terms of disability, burden, and negative impact on individuals, society, and the economy. Asthma patients often experience a decline in condition due to sudden onset symptoms. Comorbid conditions such as depression and anxiety, changes in nighttime and early morning activities, and environmental factors such as cold air can affect the quality of life of asthma patients and influence their health-seeking behavior. Methods: This study used an observational design with a literature study approach. The databases used to obtain this article are PubMed and Scopus. Results: From the literature study results, 7 articles were analyzed that met the eligibility criteria according to the inclusion and exclusion criteria. The resulting factors are associated with health-seeking behavior and quality of life in asthma patients. Conclusion: This study states that factors associated with health-seeking behavior and quality of life in asthma patients include education, distance to health facilities, socio-economic factors, age, employment status, gender, obesity, and anxiety/depression.
Review artikel: analisis faktor yang mempengaruhi kejadian pneumonia pada bayi dan balita Sholih, Mally Ghinan; Mulki, Munir Alinu; Julianti, Nurlia; Jannah, Roudotul; Indriyani, Yuni Lili
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 2 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i2.386

Abstract

Pneumonia is an infection of the lower respiratory tract which is the main cause of death in toddlers and children. Although there is a lot of information about risk factors for pneumonia, there is information that is not presented in detail and specifically. The purpose of this review article is to provide insight into the risk factors that cause pneumonia in babies and toddlers, making us more alert and aware of the importance of preventing and treating pneumonia, especially in babies and toddlers. The review method for this article is a literature review. The database comes from national and international journals via Google Scholar and PubMed databases published in the years 2013-2023. The results and discussion of this review include information about pneumonia, risk factors for pneumonia, and factors causing pneumonia in infants and toddlers. Based on the articles that have been reviewed, it shows that the factors that influence the incidence of pneumonia are exposure to cigarette smoke, LBW, nutritional status, gender, and history of exclusive breastfeeding. 
Uji Aktivitas Antihiperlipidemia Ekstrak Etil Asetat Daun Jambu Air (Syzygium aqueum) terhadap Kadar Kolesterol Total pada Tikus Jantan Galur Wistar Setianingsih, Siti; Sumantri, Sumantri; ‘Afiah, Noni Faridatul
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 2 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i2.420

Abstract

The ethyl acetate extract of guava leaves contains secondary metabolites in the form of flavonoids and alcaloids which have been shown to have an antiperlipidemic. This study aims to determine the content and levels of the ethyl acetate extract of water guava leaves (EEADJA) and antihyperlipidemic activity in hyperlipidemic rats.This research was an experimental study with a randomized matched pre-test and post-test control group design . Hyperlipidemic rats were made by giving PTU 12.5 mg/kg/day orally for 14 days. Hyperlipidemic rats were divided into 5 groups with 5 rats each, namely group I (negative control) CMC-Na 0.5%, group II (positive control) simvastatin 0.18 mg/kgBW/day, groups III, IV and V given EEADJA (100, 200, and 400) mg/kgBW/day for 14 days orally. Differences in data on total cholesterol levels before and after treatment were tested statistically by testing the antihyperlipiemia effect using the paired t-test and One Way Anova test to determine differences in the reduction in total cholesterol levels with various dose variations. EEADJA with various doses of 100, 200, and 400 mg/kg/day has the ability to reduce total cholesterol levels in the blood of hyperlipidemic rats.
Studi in silico senyawa Echinochrome-A, Spinochrome-A, and Echinamine-A pada Echinometra mathaei dalam menghambat enzim maltase-glucoamylase sebagai antidiabetes Prasetyanti, Intan; Kresnamurti, Angelica
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 2 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i2.476

Abstract

DM can be caused by the release and absorption of glucose in the small intestine by digestive enzymes. Inhibition of this enzyme can help manage DM. Human Maltase-glucoamylase (MGA) is an enzyme in the small intestine that is responsible for catalyzing the release of glucose from carbohydrate digestion. By inhibiting this enzyme, it is hoped that glucose in type 2 diabetes patients can be controlled. Analyze the potential of Echinochrome-A, Spinochrome-A, and Echinamine-A in Echinometra mathaei extract as an antidiabetic using molecular docking. Molecular docking using Echinochrome-A, Spinochrome-A, Echinamine-A as a compound test and Miglitol as standard for the Human Maltase-glucoamylase receptor. Echinochrome-A, Spinochrome-A, and Echinamine-A has an affinity and hidrogen bonds with amino acid residues that are not significantly different from Miglitol, so that Echinochrome-A, Spinochrome-A, and Echinamine-A has potential as an antidiabetic.
Analisis kadar amilosa pada pati jagung manis (Zea Mays L. Var. Saccharata) secara spektrofotometri UV-Vis Fadjria, Neri; Arfiandi, Arfiandi; Auliyah, Nabila Dhiyaul
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 2 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i2.494

Abstract

Sweet Corn Starch (Zea mays L. var. saccharata) is composed of two fractions: amylose and amylopectin. The determination of amylose content in Sweet Corn Starch is carried out using the spectrophotometric method. This method employs a 2% iodine solution as a reagent, which reacts with starch to generate a coloured solution that can be measured using a spectrophotometer. The amylose content is quantified through visible spectrophotometry, resulting in a regression equation of y ̂ = 0.006 + 25.2x, with a coefficient of determination (R2) = 0.998 and a correlation coefficient (r) = 0.9989. The amylose content in Sweet Corn Starch is determined to be 28.65%, whereas the amylopectin content is found to be 71.35%. Furthermore, the analysis provides additional parameters: Standard Deviation (SD) = ± 0.0044, Detection Limit (BD) = 0.0005 mg/ml, and Quantity Limit (BK) = 0.0018 mg/ml. These parameters offer valuable insights into the quality and properties of the sweet corn starch sample.
Faktor-Faktor yang Mempengaruhi Stunting di Indonesia : Studi PRISMA (Preferred Reporting Items for Systematic Review & Meta Analysis). Masdalena, Masdalena
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 2 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i2.504

Abstract

Stunting, a long-term nutritional problem that arises from insufficient food intake and is caused by vitamin deficiencies, has a broad and complex impact on children's health. Stunting can appear when the child is still in the womb and can occur until the child is two years old. This study explores the factors that influence stunting in Indonesia. Using the PRISMA (Preferred Reporting Items for Systematic Review & Meta-Analysis) method. Through a literature review from various sources such as Google Scholar and PubMed, this research aims to identify crucial factors related to stunting in toddlers by defining the keywords "stunting" and "stunting factors". In the identification, screening, eligibility, and analysis stages, 20 articles were selected that met the criteria for this research. Twenty (20) articles from 2019-2024 have been analysed using the PRISMA diagram. Articles from various journals were found to originate from Indonesia. Research studies show that the factors that influence stunting in Indonesia are 27.27 times compared to mothers with a higher level of education (aOR = 27.27; 95% CI = 4.37 to 170.11), with statistical significance (p = 0.00001). Internal factors influence stunting in Indonesia.
Hubungan suhu rumah dan kontak penderita dengan kejadian penularan tuberkulosis di Kecamatan Manonjaya Kabupaten Tasikmalaya Dewi, Candrawati Puspita; Raharjo , Mursid; Adi , Mateus Sakundarno
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 2 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i2.505

Abstract

Based on data from the Global Tuberculosis Report, the World Health Organization (WHO) in 2021 states that from 7.1 million in 2019 to 5.8 million in 2020, a 17% decrease, around 16 countries contributing to this decrease, namely India, Indonesia, the Philippines, were affected. worst. Reduced access to TB diagnosis and treatment has resulted in an increase in TB deaths, estimated at 1.3 million TB deaths in 2020. TB cases in Tasikmalaya Regency are still 45% and there are 36% RO TB cases (43 people) and the discovery of TB suspects has also not yet reached the target, which is only 40%. The aim of the research was to determine the relationship between house temperature and patient contact with the incidence of tuberculosis in Manonjaya District, Tasikmalaya Regency. The research design used case control. The research was conducted in March 2024 in Manonjaya District, Tasikmalaya Regency. The research sample was 128 respondents. The independent variables are the temperature of the house and the patient's contact. The dependent variable is the incidence of pulmonary tuberculosis transmission. The instrument is an observation sheet. Data were analyzed by chi square test using SPSS. This research applies the principles of confidentiality, useful information and scientific development. The results of the study showed that there was a relationship between house temperature (OR=2.15; 95% CI; 1.05-4.37) and patient contact (OR=4.31; 95% CI; 2.04-9.11) with the incidence of transmission of tuberculosis in the home. The conclusion is that there is a relationship between house temperature and patient contact with the incidence of tuberculosis in Manonjaya District, Tasikmalaya Regency. Tuberculosis sufferers and the patient's family can take preventive measures to prevent transmission of tuberculosis.
Pengaruh konseling obat terhadap pengetahuan dan tingkat kepatuhan pasien hipertensi Tahun 2023 Nainggolan , Intan; Nurasni, Nurasni; Simanjuntak, Nerly Juli Pranita; Novriani , Erida; Piska , Finna; Meutia , Rena; Neswita, Elfia
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 2 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i2.507

Abstract

Hypertension is when blood pressure exceeds normal limits, and it is generally a lifelong condition that requires maintaining stable blood pressure. Every year, the relationship between hypertension and death from heart and blood vessel disease stabilizes. Every year, the link between hypertension and death from heart and blood vessel disease is proven. This research took place from July to September 2023 at H. Adam Malik Hospital, Medan, with 53 patients who met the inclusion criteria. The study aims to assess the level of adherence of hypertensive patients to the use of their medication using the Morisky Medication Adherence Scale questionnaire and to see whether counseling can increase the level of patient compliance. The results of the analysis show that providing counseling has a significant impact on increasing compliance in hypertensive patients at H.Adam Malik General Hospital, Medan, as demonstrated by the Wilcoxon test with p-value < 0.05.
Formulasi dan uji aktivitas repellent lilin aromaterapi dari minyak atsiri serai wangi (Cymbopogon Nardus L.) dengan cengkeh (Syzygium Aromaticum L.) Ginting , Indra; Rudang , Singgar Ni; Andry, Muhammad
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 2 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i2.515

Abstract

Background: Aromatherapy candles are an alternative to inhalation therapy applications, namely the inhalation of aroma vapors produced from essential oils. Fragrant Lemongrass (Cymbopogon nardus L.) and Clove (Syzygium aromaticum L.) contain essential oil compounds that have the potential as natural pesticides. This study aims to formulate aromatherapy candles from essential oils of citronella and clove flowers as mosquito repellents with various concentrations, namely negative control, F1:1%:3%, F2: 2%:2%, and F3: 3%:1 %. The research was done experimentally by making preparations of aromatherapy candles, with preparation evaluation tests including organoleptic tests, air bubble tests, burn time tests, and melting point tests. The candle quality test includes a scent preference test, a candle effectiveness test against mosquitoes, and a therapeutic test on sleep quality using the Mi Band 5 Smartwatch. The results of the preparation evaluation test met the requirements. The most preferred scent was F2 (2%:2%). The effectiveness of wax as a repellent was very optimal in killing mosquitoes, with the best value affecting mosquito mortality shown by F3 treatment (3%:1%). The effectiveness of candles as a therapy for sleep quality showed that there was a change in the quality of sleep that was getting better, with the best value affecting sleep quality shown by the F2 treatment (2%:2%). The conclusion from the researchers of the study is that aromatherapy candle formulations from citronella and cloves can be used as mosquito repellents and also improve sleep quality.

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