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Journal of Pharmaceutical and Sciences.
Published by Universitas Tjut Nyak Dhien
ISSN : -     EISSN : 26563088     DOI : https://doi.org/10.36490/journal-jps.com
Core Subject : Health, Science, Agriculture, Engineering,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health
Journal of Pharmaceutical and Sciences (JPS) with e-ISSN: 2656-3088 is a scholarly peer-reviewed open access journal related to Pharmaceutics, Pharmacology, biotechnology, Pharmacognosy & Phytochemistry, Pharmaceutical Chemistry, Pharmaceutical Biotechnology, Pharmacy practice, Pharmacogenomics, Medicinal Chemistry, Molecular Pharmacology, Novel drug delivery system, Nanotechnology, Analytical Chemistry, Organic Chemistry, Natural Chemistry, Polymer Sciences, Clinical Pharmacy, pharmaceutical management, pharmacoeconomics, pharmacoepidemiology, clinical pharmacy, community pharmacy, social pharmacy, pharmaceutical marketing, government policies related to pharmacy, pharmaceutical care, Medical Biotechnology, Biochemistry, food chemistry, health and applied sciences relevant to the field of pharmacy. Journal of Pharmaceutical and Sciences (JPS) accepts manuscripts in Indonesian Language (Bahasa Indonesia) with titles and abstracts in bilingual, both Indonesian and English. We accept article manuscripts in the form of original research, literature reviews, and systematic reviews. We do not accept articles in the form of case reports
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 55 Documents
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Search results for , issue "JPS Volume 8 Nomor 1 (2025)" : 55 Documents clear
Formulasi sediaan lip cream ekstrak etanol bunga kecombrang (Etlingera elatior (Jack) R. M. Sm.) dan bunga rosella (Hibiscus sabdariffa L.) sebagai zat pewarna alami Rumanti, Ruth Mayana; Sari , Rika Puspita
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.744

Abstract

Introduction: The kecombrang flower and roselle flower are known as sources of natural antioxidants and have the potential to be used as natural dyes in lip cream products. Both types of flowers contain compounds such as tannins, flavonoids, and saponins. The aims of study to analyze the effect of varying concentrations of ethanol extract from the kecombrang flower (Etlingera elatior (Jack) R. M. Sm.) and the roselle flower (Hibiscus sabdariffa L.) on the color of lip cream formulations. The method of research was conducted through laboratory experiments that included sampling, extract preparation, product formulation, physical quality evaluation, and panelist preference testing. Data were analyzed descriptively by calculating the percentage of preference levels and presented in the form of tables and graphs. The results show that the preparation has a semi-solid texture, with colors ranging from light pink to dark pink in certain combinations, and a purplish pink for the 10% roselle extract formulation. The pH of the preparation is in the range of 5.1-5.4, without coarse grains, good spreadability, an average spread distance of 5.5 cm, an average adhesion time of 12.73 seconds, and no irritation. The cycling test indicates color instability, changing from light pink to dark brownish purple. Based on the hedonic test, formulation F5 has the highest preference level, which is 88.33%. The conclusion of this study is that the ethanol extract of kecombrang and rosella flowers produces a light pink lip cream that is suitable for formulation in lip cream preparations. The higher the concentration of the extract used, the darker the pink color produced, with a texture that tends to be more liquid and a decreasing pH.
Formulasi dan Evaluasi Tablet dengan Bahan Tambahan Tongkol Jagung (Zea mays L.) sebagai pengganti HPMC yang digunakan untuk Anti Diabetes Surbakti, Christica Ilsanna; Suryani , Monica; Nerdy, Nerdy
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.779

Abstract

Corn (Zea mays L) is a food crop that is known and cultivated in developing countries. So far, corn cobs have not been widely used as a value-added product. Corn cobs have 35.5% crude fiber, 2.5% protein, 0.12% calcium, 0.04% phosphorus and the remaining 38.16% of other substances. Corn cobs, which are biomass, contain phenolic phytochemicals which are very likely to be used as active antioxidant ingredients. The choice of method for making tablets is adjusted to the characteristics of the active substance used. In this research, the method used in making metformin HCl tablets was wet granulation. Wet granulation is the process of adding liquid to a powder or powder mixture in a container equipped with stirring which will produce agglomeration or granules. The evaluation results of corn cob additive granules as a substitute for HPMC showed the results of the flow time test (F1 1.5 seconds, F2 1.4 seconds F3 1.63 seconds), F1 angle of repose test (34.96 o, F2 41, 43 o, F3 41.92 o), humidity test (F1 1.794 %, F2 1.999 %, F3 2.331 %) and compressibility test (F1 11 %, F2 15%, F3 8%).  The results of the evaluation of antalgin tablets using corn cobs as a substitute for HPMC showed visual test results where the tablets were round and white in color, the weight uniformity test showed results (F1 A (5%) 708.7-783.3 and column B (10% ) 671.4-820.6, F2 A (5%) 562.775– 705.75 and column B (10%) 571.05-698.6, F3 688.75– 761.25 and column B (10%) 625.5-797.5), size uniformity test shows results (F1 diameter 1.3545 and thickness 0.4705, F2 diameter 1.359 and thickness 0.468, F3 diameter 1.36 and thickness 0.471), fragility test shows results (F1 0 .06978367 %, F2 0.53272451 %, F3 0.06978367 %) and tablet hardness showed results (F1 6.764, F2 4.984, F3 7.89) and disintegration time test showed results (F1 2 minutes, F2 2 minutes, F3 2 minute).
Drug Formulasi paper soap ekstrak etanol dedak padi (Oryza sativa L.) dan uji aktivitas antibakteri terhadap bakteri Escherichia coli dan Staphylococcus aureus Zannah , Muhamad; Dalimunthe , Gabena Indrayani; Lubis , Minda Sari; Yuniarti, Rafita
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.229

Abstract

Paper soap is soap in the form of thin sheets resembling paper. Rice bran from rice milling waste contains antibacterial compounds. The aim of this research was to formulate paper soap from rice bran ethanol extract and to determine its antibacterial activity. This research is a type of experimental research carried out in a laboratory. Includes steps such as taking and identifying samples, preparing and making ethanol extract of rice bran (Oryza sativa L.), and testing antibacterial activity against Escherichia coli using the Disc Disc method, where the inhibition zone of the ethanol extract of rice bran and the paper soap preparation is containing rice bran extract (Oryza sativa L.) was observed and measured as a result of the antibacterial activity test. The results of this research show that the ethanol extract of rice bran contains chemical compounds, namely alkaloids, flavonoids, saponins, tannins, triterpenoids/steroids and glycosides. Rice bran ethanol extract has characteristics in accordance with the 1989 MMI requirements. The results of determining the antibacterial activity of rice bran ethanol extract produce an inhibition zone against Escherechia coli bacteria ranging from 5mm - 12.5mm and Staphylococcus aureus ranging from 5.5 mm-16.67 mm. The results of the paper soap evaluation test, organoleptic examination, thickness examination, weight uniformity test, stability test, foam power test met the requirements and in the irritation tests F0, F1, F2 and F3 did not irritate the skin, in the hedonic test the most preferred formula was F1. The results of determining the antibacterial activity of paper soap produced an inhibition zone for Escherechia coli bacteria ranging from 8.16mm - 12.5mm and Staphylococcus aureus ranging from 15mm-14.83mm. From the research results it can be concluded that rice bran ethanol extract can be formulated into paper soap and has antibacterial activity.
Evaluasi kesesuaian penyimpanan obat di gudang farmasi puskesmas Ngesrep berdasarkan standar kefarmasian dan Syariat Islam Rini , Tri Diana Puspita; Rochajati , Siti; Najmi , Tusti Naida Pavita
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.239

Abstract

Pharmaceutical services are direct services and communication to patients related to pharmaceutical preparations to achieve definite results and improve patients' quality of life. Drug storage is the activity of storing and maintaining by placing received drugs in a place that is considered safe from theft and physical disturbances that can damage the quality of the drug. If there is an error in storing the drug, it will decrease the drug content and result in losses to the Health Center. This study was conducted to distribute the storage of pharmaceutical preparations in the Ngesrep Health Center pharmacy installation warehouse. This study is a type of non-experimental research, namely descriptive research conducted through observation and interviews related to storing pharmaceutical preparations through evaluation based on Permenkes Number 74 of 2016 and the Directorate General of Pharmacy and Medical Devices and analysis of drug storage indicators. Based on the results of the study, it was obtained that the suitability of the spatial storage requirements at the Ngesrep Health Center in 2024 was 90.74%, with excellent information.
Studi perbandingan profil asam lemak minyak ikan lele dan minyak ikan keting melalui pemurnian dengan bentonit Jannah, Nadia Miftahul; Ningrum, Karina Primatyas
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.378

Abstract

In general, fish have high omega-3 and omega-9 fatty acid content and are beneficial for health. This makes fish oil develop into a food supplement. Increasing the amount of free fatty acids in oil can potentially reduce the quality and damage of fish oil. Adsorbents have bleaching properties that can affect color changes in fish oil and fish oil content. This study aims to determine the effect of bentonite adsorbent treatment on the fatty acid profile of catfish oil and keting fish oil analyzed using the Gas Chromatography Mass Spectrometry (GC-MS) method. Catfish oil (CFO) and Keting fish oil (KFO) samples were extracted without using organic solvents and then treated with bentonite as an adsorbent. The extracted oil was derivatized and then injected into the GC-MS instrument system. There were 29 types of fatty acids detected in each sample, namely 12 types of saturated fatty acids (SFA), 8 types of monounsaturated fatty acids (MUFA), and 9 types of double unsaturated fatty acids (PUFA). The effect of purification with bentonite was analyzed using One-way ANOVA from Minitab19 software showing that there were differences in the content of fatty acid profiles of CFO and KFO that were purified and not purified with bentonite, shown in each category of fatty acids SFA, MUFA and PUFA which had a p value <0.05.
Optimasi formulasi dan uji fisik sediaan toner dari minyak atsiri lavender (Lavandula angustifolia l.) sebagai anti jerawat Ahmad , Rofi’uddin; Ainiyah , Nur
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.381

Abstract

Lavender is a light lavender-colored flower, has a distinctive and delicate smell, and has anti-inflammatory, antiseptic, antibacterial, antifungal, antidepressant, and can reduce acne. The purpose of this study is to make a toner preparation formulation from lavender essential oil as an anti-acne with variations in glycerin and propylene glycol concentrations so that an optimal formula is produced. The method used in this study is Simplex Lattice Design. The physical tests of toner preparations carried out include organoleptic, homogeneity, pH, dry time, and displaced volume. The response from the physical evaluation was processed to obtain the optimal formula. The results of the physical test of the optimum preparation were then analyzed using the One Sample T-Test with the SPSS application. Formula optimization yielded a concentration of 10% glycerin and 7% propylenglycol. The optimal preparation of lavender toner is clear white with a distinctive lavender smell and liquid form, a homogeneous preparation, a pH value of 6.17, a drying time of 1.12 minutes, and a transferred volume of 98 ml so that the optimal preparation of lavender toner meets the requirements of a good toner. The results of the One Sample T-Test analysis showed no difference.
Gambaran proses perencanaan dan pengadaan kebutuhan farmasi di apotek farmarin dalam perspektif Islam Nastiti, Nindita Sari; Amanda, Salsabila; Yanualisarani, Cahyani
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.402

Abstract

Medicines are a very important element in health care efforts, therefore the availability of medicines must always be guaranteed. Unsecured availability of medicines, or shortages of medicines in pharmaceutical facilities such as pharmacies, can result in lowering the level of consumer confidence. In an Islamic perspective, the need for medicine is included in maqashid al-dharuriyyat (primary needs) because it is related to preserving life or maintaining the soul (hifdz al-nafs). This research uses a descriptive method with a qualitative approach. Based on the research that has been carried out, it can be concluded that the planning and procurement process at the Farmarin pharmacy is in accordance with pharmaceutical service standards and is in accordance with the Islamic perspective, namely procurement at the Farmarin pharmacy using consumption methods and epidemiological methods and taking into account the halalness of medicines.
Karakteristik dan aktivitas antibakteri minyak atsiri daun cengkeh dari daerah cluwak terhadap bakteri Staphylococcus aureus ATCC 25923 Rahmawati , Laily Mega; Januarti , Ika Buana; Assidiqi , Elok Rosita; Rosyida , Raissa
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.484

Abstract

Essential oil is a potential wealth of Indonesia's natural resources as a raw material for medicines and cosmetics. Cengkeh leaf essential oil contains the main component of eugenol as an antibacterial. The purpose of this study was to determine the characteristics and antibacterial activity of cengkeh leaf essential oil from Cluwak region against Staphylococcus aureus ATCC 25923 bacteria. Cengkeh leaf essential oil was distilled by water vapor distillation method. Characterization of essential oil was performed on refractive index, optical rotation, and compound component analysis by GC-MS. Antibacterial activity was tested by the well diffusion method to obtain the diameter of inhibition at each concentration. Cengkeh leaf essential oil has a refractive index of 1.5303 and an optical rotation of 0.55. Analysis of the main components of the essential oil contains 7 main compound components with the highest compound m-eugenol. The diameter values of inhibition in antibacterial activity with concentrations of 10%, 20%, and 40% were 9.44 mm, 11.48 mm, and 12.37 mm, respectively. The characteristics of the essential oil are in accordance with the standard and the antibacterial activity is categorized as weak inhibition.
Artikel review : Kecantikan alami dengan kopi: panduan lengkap masker gel wajah berbasis kopi buatan Indonesia Jannah, Roudotul; Syahrin, Esti; Sudarjat, Hadi
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.521

Abstract

The increasing ‘back to nature’ trend in Indonesia has brought about a variety of beauty products infused with natural ingredients. Coffee is an Indonesian natural resource that has a variety of active compounds in it that are useful as antioxidants. The antioxidant compounds in coffee can be formulated into peel off- masks that help maintain healthy facial skin. The purpose of this review article is to determine the development and mapping of research topics on coffee masks using bibliometric analysis and to review and provide a summary of several scientific articles related to the formulation, safety, and effectiveness of arabica and robusta coffee peel-off gel mask preparations as antioxidants. The data set used was sourced from the publication of national and international scientific articles indexed by Google Scholar in the range of 2019-2024. The stages carried out include: 1) determining the topic, 2) collecting data using a reference manager in the form of Publish or Perish software, 3) processing the data obtained with Microsoft Excel software 4) conducting bibliometric analysis and visualizing it using the help of VOSviewer software and, 5) reviewing articles. The results of the bibliometric analysis showed that publications on coffee masks experienced fluctuating development.  Based on the visualization of bibliometric mapping, research on coffee masks is divided into 4 clusters consisting of 15 interrelated items. Based on the results of the review article, there are 6 original research related to the formulation and evaluation of coffee peel-off gel masks that are discussed in depth and it can be concluded that peel-off gel masks from coffee, both robusta and arabica coffee, have been proven safe and effective for the skin.
Meningkatkan Kualitas Pelayanan Farmasi: Evaluasi Sistem Penyimpanan Obat Berdasarkan Standar Kefarmasian dan Prinsip Syariat Islam di Puskesmas Tlogosari Wetan Semarang Kartika, Erza Ridha; Lola , Shofi
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.536

Abstract

Pharmaceutical Services are direct pharmaceutical service activities to patients related to the provision of medicines with the aim of obtaining clear results in order to improve the quality of patients. Pharmaceutical service standards are a benchmark used as a guideline for pharmacists in implementing pharmaceutical services. Tlogosari Wetan Health Center, Semarang City is a parent health center that has 3 auxiliary health centers, including: Kekancan Mukti Health Center, Pedurungan Kidul Health Center, and Plamongansari Health Center. This study aims to evaluate the storage of pharmaceutical preparations Based on Pharmaceutical Service Standards at Tlogosari Wetan Health Center and Based on Islamic Sharia Principles. This study is descriptive using data collection techniques, namely interviews, observations, and documentation.

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