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Jurnal Riset Ilmu Kesehatan Umum dan Farmasi
Published by Sekolah Tinggi Ilmu Kesehatan Kesetiakawanan Sosial Indonesia
ISSN : 30265819     EISSN : 30265800     DOI : 10.57213
Core Subject : Health,
Health Professions Public Health
Jurnal ini adalah Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) yang bersifat peer-review dan terbuka. Bidang kajian dalam jurnal ini termasuk riset Ilmu Kesehatan Umum, dan Farmasi.
Arjuna Subject : Profesi Kesehatan - Farmasi
Articles 217 Documents
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Perbandingan Aktivitas Antibakteri pada Berbagai Konsentrasi Ekstrak Bunga Telang (Clitoria ternatea L.) terhadap Staphylococcus aureus: Suatu Tinjauan Naratif Anisa Safitri; Atri Sri Ulandari; Afriyani Afriyani; Zulpakor Oktoba
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 4 No. 1 (2026): Januari : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v4i1.958

Abstract

Introduction: Staphylococcus aureus infection remains a major health problem due to the increasing resistance to conventional antibiotics. Butterfly pea flower (Clitoria ternatea L.) contains bioactive compounds with potential antibacterial properties. This study aimed to evaluate the antibacterial effectiveness of butterfly pea flower extract and to assess the effect of extract concentration variation against Staphylococcus aureus. Method: This study employed a narrative literature review by searching articles from Google Scholar (1,130 articles), PubMed (2 articles), and ScienceDirect (235 articles) published between 2015 and 2025. Articles were selected based on inclusion criteria, namely experimental studies using Staphylococcus aureus as the test bacterium and reporting variations in butterfly pea flower extract concentrations. Exclusion criteria included review articles or proceedings, studies without inhibition zone data, studies not using Staphylococcus aureus, and articles not available in full text. Articles meeting the criteria were analyzed descriptively and comparatively (n = 9 articles). Discussion: Analysis of the nine selected studies indicated that increasing concentrations of butterfly pea flower extract were associated with larger inhibition zones against Staphylococcus aureus. Variations in results were influenced by solvent type, extraction methods, and antibacterial testing techniques. Conclusion: Butterfly pea flower extract demonstrated consistent antibacterial activity against Staphylococcus aureus, particularly at higher concentrations, suggesting its potential development as a natural antibacterial active ingredient.
Hubungan Kecanduan Media Sosial terhadap Kejadian Cyberbullying pada Remaja di Kota Semarang Salwa Aiza Zahra; Betie Febriana; Wahyu Endang
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 4 No. 1 (2026): Januari : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v4i1.962

Abstract

Excessive use of social media among adolescents may lead to addiction, which increases the risk of aggressive online behavior such as cyberbullying. This study aims to anlyze the relationship between social media addiction and the incidence of cyberbullying among adolescents in Semarang City. A quantitative method with a cross-sectiona. design was employed, involving 320 high school students from four public schools in semarang. Date were collected using the Social Media Addiction Scale–Student Form (SMAS–SF) and the Cyber Victimization Scale (CVS). Data were analyzed using the Spearman Rank correlation test. The results revealed a significant relationship between social media addiction and cyberbullying (r = 0,368; p = 0,000). This finding indicates that higher levels of social media addiction are associated with greater involvement in cyberbullying, both as perpetrators and victims. In comclusion, social media addiction contributes to the rise of cyberbullying behavior among adolescents. It is recommended that adolescents improve self-control and digital literacy, while parents and educational institutions enhance supervision and education on responsible sociam media use.
Peran Pelayanan Apoteker terhadap Pengetahuan Swamedikasi Obat Bebas dan Bebas Terbatas di Apotek M. Dwi Suprobo; Pamungkas Aji
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 4 No. 1 (2026): Januari : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v4i1.723

Abstract

Self Medication is self treatment, starting from the onset of symtoms to the selection and use of medications. Pharmacists provide information to the public on drug selection for self medication to ensure appropriate treatment according to their needs. Providing self medication information is crucial for improving public knowledge. This study aims to increase pharmacists' awareness in providing it to the public and increase public knowledge when using over the counter and limited over the counter drugs in Larangan - Brebes area. A total of 100 respondents participated in this study which was conducted using an observational cohort design. Data collection was conducted using a prospective pre-test and post-test. The analysis used a  non-parametric t-test using the Wilcoxon alternative  test. The respondents’ educational status was dominated by high school graduates or equivalent, and 54 respondents visited the pharmacy less then five times per month. The results obtained from this study were p = 0.001 and the difference knowledge score was 11.22, with an average pre-test score of 27.54 and post-test 38.76. There were significant results on knowledge of self medication for over the counter and limited over the counter drugs after pharmacists provided services.
Hubungan Kepatuhan Minum Obat dan Gaya Hidup terhadap Kestabilan Tekanan Darah pada Pasien Hipertensi di Rumah Sakit Permata Medika Semarang Amalia Safinatun Naja; Maulidta Karunianingtyas W
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 4 No. 2 (2026): April : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v4i2.971

Abstract

Hypertension is a health problem that can increase the risk of cardiovascular disease and other complications. Hypertension is often referred to as a silent killer because it often doesn't cause obvious symptoms until complications develop. Hypertension can be controlled through pharmacological therapy with medication adherence and non-pharmacological therapy through adopting a healthy lifestyle. However, many patients do not optimally implement these measures, resulting in unstable blood pressure. This study aims to determine the relationship between medication adherence and lifestyle and blood pressure stability in hypertensive patients at Permata Medika Hospital, Semarang. This study used a quantitative method with a cross-sectional design on 79 outpatients with hypertension selected using a purposive sampling technique. Data were collected using the MMAS-8 questionnaire, a lifestyle questionnaire, and blood pressure measurements, then analyzed using the Spearman Rank test. The results of the study showed a significant relationship between medication adherence and blood pressure stability (p = 0.001; r = 0.842) and between lifestyle and blood pressure stability (p = 0.001; r = 1.000). This indicates that the more patient adherence to medication and the better lifestyle they adopt, the more stable their blood pressure. There is a significant relationship between medication adherence and lifestyle on blood pressure stability in hypertensive patients at Permata Medika Hospital Semarang.
Hubungan antara Kerusakan DNA dan Mekanisme Perbaikan Seluler: Tinjauan Literatur Azizah Zahra Nur Fitria; Margaretha Alesandria Natasya Weka; Azlinatul Lulu Kharolaini; Desi Rahmasari; Pramai Sheila Eka Khoireina; Feni Atika Tsuroyya; Septi Puspita Kurniawati; Tyara Avrilyanti Ghea Indriansyah; Liss Dyah Dewi Arini
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 4 No. 2 (2026): April : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v4i2.972

Abstract

DNA damage is a fundamental biological phenomenon that occurs due to endogenous and exogenous factors such as radiation, chemical exposure, and replication errors. If not properly repaired, DNA damage can lead to genomic instability, mutations, and the development of various diseases, including cancer. This literature review aims to examine the relationship between DNA damage and cellular repair mechanisms in maintaining genomic integrity. The method used in this study is a literature review of national scientific journals that discuss types of DNA damage, molecular markers of DNA damage, and cellular repair pathways. The findings indicate that cells possess complex and coordinated DNA repair systems, including base excision repair, nucleotide excision repair, mismatch repair, and double-strand break repair mechanisms, which play crucial roles in preserving cellular stability. The effectiveness of these repair mechanisms is influenced by the type and extent of DNA damage. Understanding the interaction between DNA damage and repair pathways provides important implications for the development of disease prevention strategies, diagnostic biomarkers, and therapeutic approaches in molecular biology and medical sciences.
Efektifitas Penerapan Terapi Afirmasi Positif untuk Menurunkan Tanda dan Gejala Harga Diri Rendah Pada Pasien Skizofrenia di Panti Gramesia Cirebon Putri Nurfitriani; Meyra Nur Rizkyllah2
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 4 No. 1 (2026): Januari : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v4i2.973

Abstract

Schizophrenia is a severe mental disorder that affects multiple psychological functions, including cognitive processes, communication abilities, and emotional expression. According to the World Health Organization (WHO) in 2019, approximately 20 million people worldwide were living with schizophrenia. One of the common problems experienced by individuals with schizophrenia is low self-esteem. This study aimed to evaluate the effectiveness of Positive Affirmation Therapy in reducing symptoms of low self-esteem among patients at Panti Gramesia Cirebon. The method employed was a nursing care report structured according to the stages of the nursing process, including assessment, diagnosis, planning, implementation, and evaluation. The intervention was conducted in three sessions, each lasting one hour. Observational findings indicated an improvement in the patient’s condition following the intervention. Initially, the score of low self-esteem signs and symptoms was 29. After the implementation of therapy, the score gradually decreased to 22. These findings suggest that the combination of pharmacotherapy and Positive Affirmation Therapy contributed to the reduction of low self-esteem manifestations. In conclusion, Positive Affirmation Therapy shows potential effectiveness in decreasing symptoms of low self-esteem and supporting improvements in patients’ quality of life.
Pengembangan Nanoemulsi dari Bahan Alam Famili Anacardiaceae sebagai Sistem Penghantaran Senyawa Aktif Antibakteri: Narrative Review Loisa Nopratity Reza; Afriyani Afriyani; Atri Sri Ulandari; Ramadhan Triyandi
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 4 No. 2 (2026): April : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v4i2.975

Abstract

Antibiotic resistance has become a major global health concern, prompting the exploration of natural antibacterial agents and advanced drug delivery systems. Plants from the Anacardiaceae family are known to contain various bioactive compounds, such as phenolics, flavonoids, terpenoids, and fatty acids, which exhibit antibacterial properties. However, the effectiveness of these compounds is often limited by poor solubility and stability. This study aimed to analyze the development of nanoemulsion formulations derived from Anacardiaceae plants as antibacterial delivery systems through a narrative review approach. Literature was collected from NCBI and Google Scholar databases using relevant keywords, resulting in six eligible research articles published between 2016 and 2025. The findings indicate that nanoemulsions produced using both high-energy and low-energy methods exhibit droplet sizes within the nanometer range, with low-energy methods generally producing smaller and more homogeneous droplets. Nevertheless, antibacterial activity varied from weak to strong depending on plant species and bioactive composition, and was not directly correlated with droplet size alone. Overall, nanoemulsions enhance the stability and delivery of bioactive compounds, but their antibacterial effectiveness is strongly influenced by formulation optimization and the type of active compounds. These findings highlight the importance of systematic formulation strategies in developing effective natural antibacterial nanoemulsions Keywords: Anacardiaceae, Antibacterial activity, Nanoemulsion
The Effectiveness of Chamomile Aromatherapy on Sleep Quality in Infants Aged 6-8 Months at the Tosa Community Health Center, Tidore Islands City Putri Ayu Ibrahim; Anik Purwati
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 4 No. 1 (2026): Januari : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v4i1.977

Abstract

Sleep disturbances in infants aged 6–8 months are a common problem encountered in midwifery practice and pediatric healthcare, and can impact infant growth, neurological development, and emotional balance. Midwives play a crucial role in providing education and safe, non-pharmacological methods to enhance the quality of a baby's sleep. Chamomile aromatherapy, which has a slight sedative and soothing effect, is one possible additional treatment. The purpose of this study was to examine how well infants at the Tosa Community Health Center in Tidore Islands City, ages 6 to 8 months, slept after receiving chamomile aromatherapy. The study employed a pretest–posttest control group methodology in a quasi-experimental design. For seven days in a row, the intervention group used a diffuser to provide chamomile aromatherapy 20 minutes before bed, while the control group did not receive any intervention. The Brief Infant Sleep Questionnaire (BISQ), which measures sleep length at night, frequency of awakenings, total sleep duration, and effective sleep, was used to assess the quality of infant sleep. The intervention group significantly outperformed the control group on every measure of sleep quality (p < 0.05). In newborns between the ages of six and eight months, chamomile aromatherapy has been demonstrated to be beneficial in improving the length and quality of sleep as well as decreasing the number of awakenings. This intervention can be recommended as part of complementary midwifery care in promotive and preventive efforts to improve the quality of infant growth and development in primary healthcare settings.
Asuhan Keperawatan pada Pasien Gangguan Integritas Kulit dan Jaringan dengan Penerapan Perawatan Luka Ganggren Menggunakan Hydrogel Laurina Tuto Beleker; Veroneka Yosefpa Windahadayani; Sri Indaryati
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 4 No. 2 (2026): April : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v2i2.976

Abstract

Gangrenous wounds can be caused by increased blood sugar or hyperglycemia. Gangrenous wounds persist for a long time, and if not treated properly, can progress to sepsis. This requires longer and more expensive treatment, and can have fatal consequences, requiring amputation of the gangrenous wound. Therefore, one Evidence-Based Practice (EBP)-based intervention is treating gangrenous wounds using hydrogel. This case study aims to provide nursing care to patients with impaired skin and tissue integrity with the application of gangrenous wound treatment using hydrogel. This case study method uses a descriptive method with a nursing care approach. Nursing care was provided to three respondents who met the criteria: patients with gangrenous wounds due to diabetes mellitus and hospitalization. Data were collected through interviews, observations using the Bates-Jansen Wound Assessment tool (BWAT) scale, and physical examinations. The results of the EBP wound care application using hydrogel showed changes in each patient. Patient 1, based on the BWAT scale, scored 96 cm (grade 4) on the first day, 96 (grade 4) on the second day, 75 (grade 4) on the third day, 12 cm (grade 1) on the second day, 12 cm (grade 1) on the third day, 9 cm (grade 1) on the third day, and 63 cm (grade 4) on the first day, 63 (grade 4) on the second day, and 48 (grade 4) on the third day. It was concluded that changes were observed in all patients, with the wound size decreasing and the wound condition improving. It is recommended that nurses apply hydrogel for the treatment of gangrenous wounds.
Penerapan Thought Stopping terhadap Penurunan Derajat Keparahan Psoriasis Eka Kusumawati; Aniska Indah Fari; Veroneka Y. Windahandayani
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 4 No. 2 (2026): April : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v4i2.978

Abstract

Psoriasis is a chronic inflammatory skin disease influenced by psychological factors such as stress and negative thoughts that may exacerbate recurrence. Patients often experience anxiety, overthinking, and sleep disturbances, affecting clinical stability. This study aimed to analyze the implementation of nursing care using the thought stopping technique to reduce psychological stress and maintain psoriasis stability. A case study design was applied to three patients with varying severity levels. The intervention was conducted over two months through several sessions with periodic evaluation. Data were collected using nursing assessment, the Perceived Stress Scale-10 (PSS-10), and clinical observation. The findings showed a decrease in stress and anxiety levels in all patients, with no worsening of clinical conditions during the intervention period. Subjective complaints such as itching were reduced, and skin conditions remained stable. The implementation of this intervention implies that thought stopping can be used as an effective non-pharmacological nursing approach to manage psychological stress and support clinical stability in psoriasis patients.

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