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INDONESIA
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi
Published by Sekolah Tinggi Ilmu Kesehatan Kesetiakawanan Sosial Indonesia
ISSN : 30265819     EISSN : 30265800     DOI : 10.57213
Core Subject : Health,
Health Professions Public Health
Jurnal ini adalah Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) yang bersifat peer-review dan terbuka. Bidang kajian dalam jurnal ini termasuk riset Ilmu Kesehatan Umum, dan Farmasi.
Arjuna Subject : Profesi Kesehatan - Farmasi
Articles 227 Documents
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Review Artikel: Evaluasi Mutu Fisik Sediaan Kapsul dalam Menjamin Kualitas Produk Farmasi Elvira Silvany Zahara; Yasmine Eka Maulidya; Vira Maulidya; Helmalia Jelita Putri; Namira Salsabilah; Dewi Rahmawati; Yani Ambari; Dzakiyah Zhihrotulwillah
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 4 No. 3 (2026): Juli: Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v4i3.1080

Abstract

Capsules are one of the most commonly used oral pharmaceutical dosage forms due to their ease of administration, ability to mask unpleasant tastes, and flexibility in formulation development. To ensure product quality, safety, and therapeutic effectiveness, capsule preparations must comply with physical quality requirements based on pharmacopoeial standards. This review article aims to analyze the physical quality evaluation parameters of capsule preparations in maintaining pharmaceutical product quality. The method used was a literature review of scientific articles obtained from databases such as Google Scholar, PubMed, and ScienceDirect, with publication years ranging from 2020 to 2026. From the collected literature, five relevant research articles were selected based on the focus of the study. The evaluation parameters discussed include granule flow properties, weight uniformity, disintegration time, and capsule content characteristics related to drug release. The results show that good granule flow properties affect the capsule filling process and weight consistency. In addition, disintegration time serves as an important parameter in determining the ability of capsules to release active ingredients. Capsule type and formulation composition, including HPMC-based enteric capsules, also influence drug release characteristics. Therefore, physical quality evaluation is essential to ensure the stability, quality, and therapeutic efficacy of capsule pharmaceutical products.
Kepatuhan Penggunaan Obat pada Pasien Geriatri dengan Polifarmasi Retno Wulan D; Rusdiana Tri; Jihan Fahiroh; Elvira Silvany; Yasmine Eka; Vira Maulidya; Helmalia Jelita; Marscha Dwi; Mulia Maharani; Bella Fevi
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 4 No. 3 (2026): Juli: Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v4i3.1081

Abstract

Polypharmacy in geriatric patients is the concurrent use of multiple medications that commonly occurs due to chronic diseases and multimorbidity. This condition can increase the risk of drug related problems (DRPs), adverse drug reactions, and decreased medication adherence among elderly patients. This study aimed to determine the relationship between polypharmacy and medication adherence in geriatric patients and to identify efforts that can improve adherence to therapy. The research method used was a literature review by searching articles through Google Scholar, PubMed, and ScienceDirect databases using the keywords “polypharmacy,” “medication adherence,” and “geriatric.” A total of 11 national and international journals published between 2016–2026 were selected according to the inclusion criteria. The review results showed that polypharmacy is associated with low medication adherence in geriatric patients due to therapy complexity, the large number of medications used, and cognitive limitations in elderly patients. Poor medication adherence may increase the risk of drug interactions, hospitalization, and therapeutic failure. Several interventions were found to be effective in improving adherence, including education and counseling by pharmacists, family support, therapy simplification through deprescribing, and the use of medication reminder applications. Therefore, the role of healthcare professionals and family support is essential in improving medication adherence and therapeutic outcomes in geriatric patients with polypharmacy.
Perbandingan Hasil Identifikasi Tricophyton Sp. dengan metode Mikroskop dan Kultur Amelia Putri Az Zahra; Azlinatul Lulu Kharolaini; Elsa Oktavia Ramadhani; Pramai Sheila Eka Khoireina; Pramesti Listanto; Juwita Ramadhani Octavianingrum; Liss Dyah Dewi Arini
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 4 No. 3 (2026): Juli: Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v4i3.1082

Abstract

Trichophyton is a genus of dermatophytes that most frequently causes superficial infections in humans, particularly tinea capitis, tinea corporis, tinea pedis, and onychomycosis. Accurate identification of Trichophyton species is crucial for determining appropriate antifungal therapy. Routine dermatophyte identification has relied on macroscopic and microscopic morphology, but this approach is considered time-consuming. This article compares the results of Trichophyton fungal observations using two main approaches: direct microscopic observation using KOH solution and culture methods on selective media such as Sabouraud Dextrose Agar (SDA). Phenotype-based identification is performed through colony characteristics in culture and microscopic examination in lactophenol cotton blue preparations. From KOH and culture examinations of clinical samples, the positivity rate by KOH is generally higher than that by culture, although culture remains the reference standard for dermatophyte species identification. From KOH and culture examinations of clinical samples, the positivity rate by KOH is generally higher than that by culture, although culture remains the reference standard for dermatophyte species identification. A comprehensive understanding of these two methods is expected to improve the accuracy of clinical mycological diagnoses and support more targeted therapeutic management.
Uji Aktivitas Antibakteri Ekstrak Etanol Daun Meniran (Phyllanthus Niruri L.) -terhadap Bakteri Staphylococcus Aureus Nurainun Badriani; Ririn Alfa Nia
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 4 No. 3 (2026): Juli: Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v4i3.1084

Abstract

Background: Staphylococcus aureus is a pathogenic bacterium that can cause various infections in humans. The irrational use of antibiotics has contributed to the emergence of bacterial resistance, highlighting the need for alternative antibacterial agents derived from natural products. Meniran leaves (Phyllanthus niruri L.) are known to contain bioactive compounds such as flavonoids, alkaloids, tannins, and saponins, which have potential antibacterial properties. Objective: This study aimed to evaluate the antibacterial activity of ethanol extract of meniran leaves (Phyllanthus niruri L.) against Staphylococcus aureus and to determine the most effective concentration for inhibiting bacterial growth. Methods: This experimental laboratory study employed the disc diffusion method. Ethanol extract of meniran leaves was tested at concentrations of 10%, 50%, and 70%. Chloramphenicol was used as the positive control, while DMSO served as the negative control. Data were analyzed using One-Way ANOVA. Results: Phytochemical screening revealed the presence of flavonoids, alkaloids, tannins, and saponins in the ethanol extract. The antibacterial activity test showed inhibition zone diameters of 7.45 mm, 10.35 mm, and 12.06 mm at concentrations of 10%, 50%, and 70%, respectively. Statistical analysis indicated significant differences among treatment groups (p < 0.05). Conclusion: The ethanol extract of meniran leaves (Phyllanthus niruri L.) exhibited antibacterial activity against Staphylococcus aureus. The 70% concentration demonstrated the strongest inhibitory effect on bacterial growth.  
Penerapan Kompres Jahe (Zingiber Officinale) terhadap Penurunan Nyeri pada Lansia dengan Asam Urat Diah Ayu Saputri; Vincencius Surani; Sri Indaryati
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 4 No. 3 (2026): Juli: Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v4i3.1086

Abstract

Uric acid levels exceeding the normal range can lead to various clinical manifestations, such as joint pain and stiffness, tingling sensations, and swelling and erythema resulting from inflammation. Patients may also experience prolonged fatigue, general discomfort, and urinary disturbances; in some cases, acute attacks may be accompanied by an elevated body temperature or fever. A warm ginger compress is a traditional remedy or alternative therapy that combines heat application with ginger to alleviate pain. Objective: To implement an evidence-based nursing intervention for elderly patients suffering from joint pain due to high uric acid levels. Methods: This study employed a case study design involving the administration of ginger compresses within a nursing care framework. Three respondents participated in the study; the intervention was administered once daily for three days—from June 20, 2026, to June 22, 2026—at Bhayangkara Mohammad Hasan Hospital in Palembang, South Sumatra. Results: Following the three-day application of the evidence-based ginger compress intervention, the nursing issues of acute pain, impaired comfort, and knowledge deficit were successfully resolved at Bhayangkara Mohammad Hasan Hospital. Recommendations: It is hoped that the implementation of this evidence-based practice will contribute to the body of knowledge and provide further information regarding the use of ginger compresses to reduce joint pain associated with high uric acid levels in the elderly.
Penerapan Senam Kaki terhadap Diabetic Sensorymotor Polyneuropathy dan Gula Darah Sewaktu pada Penderita Diabetes Melitus Mona Destriana; Sanny Frisca; Veroneka Yosefpa Windahandayani
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 4 No. 3 (2026): Juli: Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v4i3.1092

Abstract

Diabetic Sensorimotor Polyneuropathy (DSPN) is a common chronic complication of diabetes mellitus caused by persistent hyperglycemia, resulting in sensory, motor, and autonomic nerve damage, particularly in the lower extremities. DSPN increases the risk of diabetic foot ulcers, infections, and amputations. Previous studies by Astuti and Ritonga showed that diabetic foot exercises can improve peripheral neuropathy and reduce blood glucose levels. To evaluate the effect of diabetic foot exercises on DSPN and random blood glucose (RBG) levels in patients with diabetes mellitus. This evidence-based practice (EBP) implementation involved three patients with diabetes mellitus. Random blood glucose was measured using a glucometer, while DSPN was assessed using the Neuropathy Symptom Score (NSS) and Neuropathy Disability Score (NDS). Foot exercises were performed twice daily for four consecutive days following the standard operating procedure. All respondents showed decreased RBG levels. Nursing assessment identified unstable blood glucose levels, ineffective peripheral tissue perfusion, and deficient knowledge regarding a healthy lifestyle. The average RBG reduction was 12.8%, with improved NSS and NDS scores. After four days, all respondents demonstrated lower RBG levels and improved DSPN status. Diabetic foot exercise may serve as an effective complementary nursing intervention to improve glycemic control and peripheral nerve function.
Inventarisasi Tanaman Berkhasiat Obat di Desa Gololada Kabupaten Manggarai Timur Klaudia Marlina Magung; Samuel David I. Makoil
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 4 No. 3 (2026): Juli: Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v4i3.1091

Abstract

Background: Medicinal plants are biological resources traditionally used by communities based on knowledge passed down through generations. However, changes over time may lead to the loss of this knowledge, making documentation and inventory essential for preserving local wisdom. Objective: This study aimed to inventory medicinal plants used by traditional healers (hatra) in Gololada Village, East Manggarai Regency, including plant types, parts used, processing methods, properties, and rules of use. Methods: This research employed a descriptive method with an observational design. Data were collected through observation, structured interviews, and documentation involving seven traditional healers selected using purposive sampling. Data were analyzed descriptively. Results: The study identified 32 medicinal plant species. Leaves were the most frequently used plant part (60.60%), while boiling was the most common processing method (51.85%). The plants were used to help treat various health problems, including digestive disorders, hypertension, diabetes, kidney stones, skin diseases, coughs, rheumatism, and insomnia, as well as to increase endurance. The most common usage frequency was once daily. Conclusion: Traditional healers in Gololada Village continue to maintain the use of medicinal plants as part of traditional medicine. The inventory provides information to support the preservation of local wisdom and future medicinal plant research.

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