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Andhika Lungguh Perceka
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Jurnal Medika Farmaka
Published by Sekolah Tinggi Ilmu Kesehatan Karsa Husada Garut
ISSN : -     EISSN : 2987372X     DOI : https://doi.org/10.33482/jmedfarm.v1i3
Core Subject : Science, Engineering,
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Immunology & microbiology
Jurnal Medika Farmaka (JMF) adalah jurnal ilmiah di bidang kefarmasian yang dikelola oleh program studi D-3 Farmasi STIKes Karsa Husada Garut di bawah naungan LP4M STIKes Karsa Husada Garut. JMF telah memiliki e-ISSN 2987-372X dengan Nomor SK: 2987372X/II.7.4/SK.ISSN/06/2023) sejak 07 Juni 2023 dan berlaku mulai dari Volume 1 No. 1, April 2023. Jurnal ini diinisiasi oleh "Ikatan Apoteker Indonesia" (IAI) Kabupaten Garut sejak tahun 2023. JMF menerima naskah artikel dalam dua area utama di bidang farmasi diantaranya: Sains Farmasi Biologi Farmasi & Farmakognosi Kimia Farmasi Analisis & Kimia Medisinal Teknologi Farmasi & Farmasetika Farmakologi & Toksikologi Bioteknologi Farmasi Klinis & Komunitas. Farmasi Rumah Sakit Farmasi Klinis Manajemen Farmasi Farmasi Sosial
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 51 Documents
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Review Artikel Pengembangan Penyalutan Tablet Terhadap Kualitas dan Mekanisme Obat: Review Artikel Pengembangan Penyalutan Tablet Terhadap Kualitas dan Mekanisme Obat Pratama, Reza; Rodinah, Ina; Bokotei, Martini; willis, Hawa; Oktapiani, Selvia; Hostati, Febri; Pahlevi, Muhammad Reza
Jurnal Medika Farmaka Vol 2 No 2 (2024): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v2i2.24

Abstract

Introduction: Tablets are the most popular dosage form to be given to patients, with most of the tablets produced having a thin layer of film coating. Method: used in studying the development of tablets with coating is Systematic Literature Review (SLR). Result: There are various methods to reduce product failure and development costs. Real-time assessment of coating quality is essential, especially in automated production. Therefore, the implementation of PAT is the latest trend for more effective monitoring and control of pharmaceutical unit operations. In addition to PAT, computational modeling is also actively used to aid in understanding, prediction, and problem-solving in film coating operations. Conclusion. Based on the journal review, it can be concluded that coating can be done for various purposes, ranging from improving the physical properties of tablets to improving the stability of tablets in the tablet manufacturing process. Keywords: tablet coating, tablet development, coating development, tablet coating development.
Review : Pengembangan Sediaan Padat Dengan Penghantaran Sistem Target Pratama, Reza; Febryanthi, Anggita Yayuk; Sau, Barth Larson Boling; Cahyani, Dhiana Eka; Soares, Fidelia Gabriela Da Costa; Pahlevi, Muhammad Reza
Jurnal Medika Farmaka Vol 2 No 2 (2024): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v2i2.25

Abstract

Pendahuluan : Pengembangan sediaan padat dengan sistem penghantaran target merupakan salah satu inovasi dalam bidang farmasi yang bertujuan untuk meningkatkan efikasi dan keamanan obat. Sistem penghantaran target memungkinkan obat untuk secara selektif mencapai situs aksi tertentu dalam tubuh, sehingga mengurangi efek samping dan meningkatkan konsentrasi obat pada area yang diinginkan. Sistem ini mengintegrasikan teknologi formulasi terkini dan bahan pembantu untuk merancang sediaan obat yang mampu melepaskan bahan aktif secara terkontrol dan terarah. Dalam kajian ini, berbagai metode penghantaran target dieksplorasi, termasuk penggunaan nanopartikel dan liposom yang dapat mengenali reseptor pada sel target. Metode : Studi literatur menggunakan jurnal nasional dan jurnal internasional. Hasil : Penelitian menunjukkan bahwa sistem penghantaran target dapat secara signifikan meningkatkan bioavailabilitas obat, mengurangi efek samping, dan meningkatkan kepatuhan pasien terhadap regimen pengobatan. Kesimpulan : Sistem penghantaran target sediaan padat berpotensi untuk meningkatkan efektivitas dan keamanan terapi obat. Sistem penghantaran tablet dapat memungkinkan obat secara selektif. mencapai dan bekerja bekerja pada lokasi tertentu dalam tubuh, yang secara signifikan dapat mengurangi efek samping, dan meningkatkan konsentrasi obat pada area target seperti pada lambung, ginjal dan usus.
Gambaran Tingkat Pengetahuan Swamedikasi Penggunaan Obat Analgetik Antipiretik pada Masyarakat Kelurahan Kenanga Kota Tangerang Haryanto, Kusno; Marlindasari, Liskha
Jurnal Medika Farmaka Vol 2 No 2 (2024): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v2i2.26

Abstract

One of the reasons many people do self-medication is the development of information technology via the internet and mass media about medicine. Another reason is to save costs, save time, and drugs for disorders such as pain and fever are easily found in pharmacies and drug stalls. The most widely used drug in self-medication is Paracetamol. The indication of Paracetamol is as an antipyretic analgesic, side effects of Paracetamol such as nausea, dizziness, vomiting, and long-term use can cause liver damage. This type of research uses descriptive quantitative. Quantitative research is a technique used to process data in the form of numbers, either as a result of measurement or conventional results. This study describes the level of knowledge of self-medication using antipyretic analgesic drugs in the community of Kenanga Village, Cipondoh, Tangerang City. The population in this study was the people of Kenanga Village, Cipondoh, Tangerang City RT 02 RW 01 as many as 302 people. Determination of the number of respondents using the Slovin rule so that the number of samples obtained was 80 respondents. The results showed that 49 respondents (61.25%) had good knowledge, 27 respondents (33.75%) had sufficient knowledge and 4 respondents (5%) had poor knowledge
UJI AKTIVITAS ANTIOKSIDAN SEDIAAN SABUN CAIR DARI EKSTRAK KULIT SINGKONG (Manihot esculenta Crantz) Sukmawati; Ihwanudin Subagja, Ilham; Tantri , Elisa
Jurnal Medika Farmaka Vol 3 No 2 (2025): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v3i2.66

Abstract

Introduction: Cassava peels contain phenolic compounds such as tannins, flavonoids that act as antioxidants that can inhibit free radical activity. The purposeof this study was to make a liquid soap formulation from cassava peel extract and determinate the most powerful antioxidant levels contained in the liquid soap formula. Method includes experimental research by making several formulas of cassava peel extract liquid soap preparations with concentrations of 5%, 10%, and 15%, then conducting physical evaluation tests and antioxidant activity test using Uv-Vis spectrophotometry. Result: The test results were described in tabular form and analyzed with One Way ANOVA statistics followed by post hoc (LSD) to find differences in the percentage of antioxidant activity from various concentrations. The results of antioxidant activity research from the three formulas have IC50 values FI (5%) 96,415 ppm (strong), FII (10%) 101,774 ppm ( medium), and FIII (15%) 101,322 ppm (medium). The amount of concentration in each formula affects the amount of antioxidant activity in it. The results of the One Way ANOVA test obtained a significance value of (p<0,001) which shows that there is a difference in antioxidant activity in each formula. Conclusion. this study is that cassava peel extract can be formulated into antioxidant liquid soap preparations but has not met the standards of physical quality stability of good preparations and the highest antioxidant activity is found in FI (5%) at 96, 415 ppm.
Farmasi dan Teori Konstitusi Nusantara: Apoteker sebagai Penjaga Keseimbangan Etis dan Hukum Lokal Sudrajat, Hendra; Dita, Rahma
Jurnal Medika Farmaka Vol 3 No 2 (2025): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v3i2.69

Abstract

This study examines the strategic role of pharmacists as ethical and legal mediators in Indonesia's pluralistic legal system. Based on the Nusantara Constitution theory, pharmacists are viewed not only as healthcare professionals but also as maintainers of the balance between state law and customary law. The research method uses a qualitative, normative-juridical approach with an interdisciplinary analysis of pharmaceutical science, constitutional law, and medical anthropology. Data were obtained through literature studies and case observations from indigenous communities in Papua, Kalimantan, and Nusa Tenggara. The results of this study indicate that pharmacists in indigenous areas face overlapping norms between professional codes of ethics, state law, and customary law. Their role as intermediaries enables culturally sensitive communication, the safe use of traditional medicines, and pharmaceutical practices based on local values. Pharmacists thus serve as a bridge between formal healthcare services and regional perspectives. This study recommends integrating local legal and cultural insights into pharmacy curricula and national policies to strengthen collaboration with customary authorities and build an inclusive, locally rooted health system.
Formulasi dan Evaluasi Tablet Hisap Ekstrak Elderberry (Sambucus nigra L.) menggunakan Metode Granulasi Kering Sulistiani, Ine; Gitalis Kustiawan, Mayas; Qiroatul Fatihah, Naila; Friza Puspita, Nazwa; Rosita, Nur; Puspa Sari, Pungki; Ahista Qolbi, Raihan; Azzahra, RD Salma; Sugiharti Murni, Resha; Puspita Tanjung, Yenni
Jurnal Medika Farmaka Vol 3 No 2 (2025): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v3i2.71

Abstract

Elderberry fruit (Sambucus nigra L.) is known to contain flavonoids, anthocyanins, vitamin C and hasantioxidant activity that has the potential to increase immunity and help relieve symptoms of upper respiratorytract infections. This study aims to formulate elderberry extract-based lozenges. The lozenges were formulatedusing the dry granulation method with variations in amprotab concentration to see its effect on tablet quality.Evaluation was carried out on the physical properties of the granules and the physical quality of the resultingtablets. The results showed that formula F2 (amprotab 16.67%) showed the characteristics closest to optimal.The evaluation of the granules had a flow rate of 18.16 g/second, an angle of repose of 20.44°, acompressibility of 10.49%, and a hausner ratio of 1.11, which means it showed good flow properties. Thetablets of this formula have a disintegration time of 9 minutes 16 seconds, friability of 0.92%, hardness of 4.5kg, average weight of 602 mg, diameter of 1.21 cm, and thickness of 0.525 cm. Parameters as uniformity ofweight and hardness of the tablets do not meet the Pharmacopoeia standards. Therefore, further optimization isneeded in the molding process and adjustment of the excipient ratio to obtain lozenges with consistent qualityand according to standards. In conclusion, the formulation of lozenges with elderberry powder has the prospectto be further developed, with formulation optimization to improve the quality of the tablets to meet all qualitystandards.Keywords: amprotab, mannitol, elderberry extract, lozenge
Nilai Teori Konstitusi Nusantara dalam Tradisi Pengobatan Lisan dan Peran Apoteker Modern Sudrajat, Hendra; Rahmawati, Nur
Jurnal Medika Farmaka Vol 3 No 2 (2025): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v3i2.72

Abstract

This study examines the integration of the values of the Indonesian Constitution, particularly the teachings of Sunan Drajat, into oral medicine practices and their relevance to the role of modern pharmacists. Values such as empathy, social justice, and community-based services embodied in Sunan Drajat's Pepali Pitu and Catur Pitulung demonstrate substantial alignment with the ethics of the pharmaceutical profession. This study employed a qualitative-descriptive approach through literature review, normative analysis, and historical methods. The results demonstrate that these values can be systematically integrated into the curriculum, training, and practice of pharmacists. Visualizations through diagrams and graphs demonstrate increased public trust in pharmacists based on local values. This integration serves as a foundation for strengthening a healthcare service model that is not only clinical but also rooted in the culture and spirituality of the community.
REVIEW JURNAL: KAJIAN ETNOFARMAKOLOGI PENGGUNAAN TANAMAN OBAT TRADISIONAL OLEH MASYARAKAT SUKU DAYAK Fatul Layly, Sari; Abuk Bria, Natalia; Girlani Bria, Adela; Kusuma Wardhana, Virgiawan; Avia Aunillah, Haya; Juwita Ratu, Elit; Aurya Agustina, Eka; Jelita Putri, Helmalia; Charles Seran Klau , Ivan
Jurnal Medika Farmaka Vol 3 No 2 (2025): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v3i2.73

Abstract

Masyarakat Suku Dayak membudidayakan tanaman yang kaya akan manfaat yang digunakan dalam pengobatan sehari-hari. Pembudidayaan ini berkembang secara turun-temurun dan menjadi bagian dari budaya mereka yang berhubungan erat dengan alam sekitar. Kajian ini bertujuan untuk mengeksplorasi etnofarmakologi tanaman yang sering digunakan sebagai obat, bagian-bagian tanaman yang digunakan dan cara penggunaan tanaman obat tradisional oleh masyarakat Suku Dayak. Kajian ini mencakup analisis fitokimia untuk mengidentifikasi senyawa aktif yang berkontribusi terhadap bioaktivitas. Literatur yang gunakan dalam review ini meliputi: Google Scholar, PubMed, Researchgate. Berdasarkan hasil review menunjukan bahwa ditemukan 10 jenis tanaman yang terdapat di Suku Dayak, yaitu: Karehau (Calllicarpa longlifolia Lam), Kaik-kaik (Uncaria cordata (Lour.) Merr), Kecapi (Sandoricum koejape Burm.f. Merr.), Kemot (Passifora foetia L.), Kumala Tawar (Coctus speciosus), Lasi (Macaranga recurvata), Bagore (Caesalpinia crista L.), Kemunting (Melastoma malabathricum), Karamunting (Rhodomyrtus tomentosa), Akar kuning (Arcangelisia flava (L.) Merr). Hal ini menegaskan pentingnya pengetahuan tradisional dalam konservasi sumber daya alam dan pengembangan obat herbal, serta memberikan wawasan baru tentang pemanfaatan berbagai tanaman obat dalam pengobatan modern
Pengaruh Infusa Jahe Merah (Zingiber officinale var. Rubrum) terhadap Pertumbuhan Bakteri Streptococcus mutans Nugraha, Yogi Rahman; Rohdiana, Aulia; Nurul; Wardani, Diah
Jurnal Medika Farmaka Vol 2 No 3 (2024): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v2i3.74

Abstract

Oral infections remain a significant public health problem in Indonesia, with dental caries being highly prevalent and primarily associated with Streptococcus mutans. The use of modern antibiotics for caries treatment often leads to side effects and bacterial resistance, prompting the search for herbal-based alternatives. Red ginger (Zingiber officinale var. rubrum) contains bioactive compounds such as flavonoids, phenols, gingerol, shogaol, and essential oils, which are known for their antibacterial activity. This study aimed to evaluate the inhibitory effect of red ginger infusion on the growth of S. mutans. A Posttest Control Group design was employed, and antibacterial activity was assessed using the disk diffusion method. Treatments consisted of a negative control (distilled water), a positive control (ciprofloxacin 5 µg), and red ginger infusion (RGI) at concentrations of 10%, 20%, and 40%. Results demonstrated an increase in inhibition zone diameter with higher concentrations of RGI. The negative control produced no inhibition, while the positive control showed the largest inhibition zone (45.05 mm). RGI at 10% yielded 7.91 mm (p=0.408), 20% yielded 14.81 mm (p=0.066), and 40% yielded 23.05 mm (p=0.022). Only the 40% concentration showed a statistically significant difference compared to the negative control (p<0.05). These findings indicate that red ginger infusion possesses antibacterial activity against S. mutans, although its effectiveness is still below that of ciprofloxacin. Therefore, red ginger may be considered as a potential herbal alternative for dental caries prevention, particularly as a supportive therapy. Further studies are required to isolate active compounds and develop more effective topical formulations.
Formulasi dan Evaluasi Sifat Fisik Serum Daun Sirih Hijau (Piper betle L.) dengan Kombinasi Kolagen Sisik Ikan Gurami (Osphronmus goramy Lac.) sebagai Penghambat Bakteri Acne Vulgaris Wardani, Diah; Fauzan Nul Hak, Moch; Nurul
Jurnal Medika Farmaka Vol 3 No 2 (2025): Jurnal Medika Farmaka
Publisher : LP4M STIKes Karsa Husada Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33482/jmedfarm.v3i2.75

Abstract

Acne vulgaris is a chronic skin disorder characterized by inflammation due to excessive sebum production and abnormal follicular desquamation. Natural ingredients are considered as promising alternatives, such as green betel leaf (Piper betle L.) containing phenols, flavonoids, and tannins with antibacterial and anti-inflammatory activity. Meanwhile, gourami fish scales (Osphronemus gouramy Lac.) are a source of type I collagen with a triple-helix structure that has potential as an anti-aging agent. This study aimed to formulate and evaluate a serum combining green betel leaf extract and gourami fish scale collagen as an inhibitor of acne vulgaris bacteria. An experimental laboratory study was conducted using three formulas with different concentrations of active ingredients. Physical evaluations included organoleptic properties, homogeneity, pH, viscosity, spreadability, and adhesion on days 7, 14, 21, and 28, along with antibacterial effectiveness testing. The results showed that the best formula was 20% green betel leaf extract combined with 5% collagen, with 83.33% stability parameters fulfilled. The serum produced an inhibition zone of 29.88 mm against acne vulgaris bacteria, although viscosity did not meet the standard range (230–3000 cPs). Thus, this combination has potential as an effective natural anti-acne serum but requires viscosity optimization.

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