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Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan
Published by Asosiasi Riset Ilmu Kesehatan Indonesia
ISSN : 3031013X     EISSN : 30310148     DOI : 10.61132
Core Subject : Health,
Health Professions Nursing Public Health
Organisasi Farmasi, Kedokteran, Kimia Organik Sintetis, Kimia Alam, Biokimia, Analisis Kimia, Kimia Fisika, Biologi, Mikrobiologi, Jaringan Budaya, Botani dan Hewan terkait Produk Farmasi, Keperawatan, Kebidanan, Analis Kesehatan, Gizi dan Kesehatan Masyarakat.
Arjuna Subject : Profesi Kesehatan - Farmasi
Articles 378 Documents
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Aktivitas Penghambatan Enzim α-Amilase Ekstrak Etanol dan Fraksi Buah Belimbing Wuluh (Averrhoa bilimbi L.) Diana Nurrah Ashari; Tiara Ajeng L.; Danang Raharjo
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 6 (2024): November : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i6.813

Abstract

The enzyme α-amylase is one of the enzymes that plays a role in the process of degrading starch into maltose and glucose. Organic compounds such as polyphenols and flavonoids are inhibitors of α-amylase. The star fruit plant (Averrhoa bilimbi L.) has α-amylase enzyme inhibition activity and has the potential to be used in the therapy of type 2 diabetes mellitus. This study aims to determine whether ethanol extract and the fraction of star fruit (Averrhoa bilimbi L.) have α-amylase enzyme inhibition activity, inhibition against α-amylase enzyme and better inhibition activity. The test of α-amylase enzyme inhibition activity was carried out using 3 test groups, namely negative control, positive control (acarbose) and samples (ethanol extract and star fruit fraction) with concentrations of 12.5 ppm, 25 ppm, 50 ppm, 100 ppm and 200 ppm. The results of testing the inhibitory activity of α-amylase enzyme of ethanol extract and the fraction of star fruit (Averrhoa bilimbi L.) obtained IC50 values of 5.581 μg/mL, 76.725 μg/mL, 43.152 μg/mL and 55.447 μg/mL, respectively. Based on these results, it can be concluded that the ethanol extract of star fruit (Averrhoa bilimbi L.) at a concentration of 200 ppm has a very strong activity in inhibiting the α-amylase enzyme with an inhibition percentage of 85.217% and an IC50 value of 5.581 μg/mL.
Optimasi Metode Microwave-Assisted Extraction (MAE) untuk Menentukan Kadar Flavonoid Total Ekstrak Etanol Kulit Pisang Kepok (Musa Paradisiaca.L) Salsabila Khoerunniyssa; Danang Raharjo; Bagas Ardiyantoro
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 6 (2024): November : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i6.814

Abstract

Indonesia is a country that has a lot of banana diversity. One of the banana plants that is widely found in Indonesia is the Kepok banana (Musa Paradisiaca.L). Kepok banana skin has a very high content of flavonoids and phenols. Flavonoids are known as good antioxidants because they can find reactive oxygen species with the phenolic hydroxyl group that flavonoids have. The aim of this research was to determine the results of the optimization of the Microwave-Assisted Extraction (MAE) method on the total flavonoid content of kapok banana peel ethanol extract. Microwave-Assisted Extraction (MAE) was done to extraction flavonoid from ethanol extract of kepok banana peel (Musa Paradisiaca.L). The sample collected from Widoro village, Karangsambung sub-district, Kebumen regency. Optimum extraction condition was determined by the Response Surface Methodology (RSM). The Box- Behnken design (BBD) was used to evaluate the influence of 3 factors with 3 levels extraction that is power level (10%, 30%, 50%), ethanol concentration (50, 70, 96%), and extraction time (3, 5 and 7 minutes) with 15 different runs. The research showed that optimum extraction condition was at 24,14 % of power level, 66,26% ethanol concentration, and time extraction of 3,52 minutes with calculations from the Design Expert program, the total flavonoid content response was 8.491 Mg QE/g. The total flavonoid content value obtained experimentally was 8,246 Mg QE/g under condition of 30 % power level, 70% ethanol concentration, and time extraction of 5 minutes. Based on the result, total flavonoid content can be significantly increased by optimizing the MAE process use RSM.
Penyuluhan Baby Gym untuk Meningkatkan Motorik dan Kesehatan Bayi pada Komunitas Kelas Ibu Bayi Balita di Puskesmas Kendalsari Kota Malang Yafi’ Helmi Jauhari
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 6 (2024): November : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i6.815

Abstract

Background: Infants aged 2 months have begun to learn body movements in the form of gross motor skills. Starting with kicking movements, straightening the hands of sideways movements and then on the stomach until at the age of 1 year the baby can walk independently. Gross motor can develop faster and better when there is stimulus from the surrounding environment. Baby gym can provide a stimulus for gross motor development. Baby gym exercises done with the person closest to the baby will be better for the baby's emotional security. Objective: Providing counseling and practice in mother and baby classes at the kendalsari health center makes mothers who have babies under 1 year old and who will have a baby can apply it at home to train their children's gross motor skills. Methods: the method used in this counseling is to provide leaflets and then education and practice. Giving some questions on the pretest and postest to find out the picture of knowledge in mothers. Results: from this activity an increased understanding of baby gym procedures and their benefits was obtained.
Pengaruh Pemberian Seduhan Kunyit Asam Terhadap Penurunan Tingkat Dismenorea pada Siswi SMPN 19 Bandar Lampung Provinsi Lampung Clara Sartika; Kamidah Kamidah
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 6 (2024): November : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i6.816

Abstract

Background: Menstruation is the process of shedding of the uterine wall (the inner layer of the endometrium) which is accompanied by bleeding that occurs repeatedly every month, except during pregnancy. Dysmenorrhea consists of primary and secondary dysmenorrhea. This study aims to determine the impact of giving sour turmeric infusion on changes in the level of dysmenorrhoea. Giving tamarind turmeric infusion on changes in desmenorrhea in female students at SMPN 19 Bandar Lampung. Research Objective: To determine the impact of giving sour turmeric infusion on changes in the level of dysmenorrhoea in female students at SMPN 19 Bandar Lampung Research Method: The type of research used is quantitative with a cross sectional approach. Pre-experimental research design with a one group pretest-posttest design without a control group. The sampling technique uses the Accidental Sampling technique. The data analysis technique used is the Wilcoxon test. Research result : Giving tamarind turmeric is a feasible intervention given to reduce dysmenorrhea pain experienced by young women. Suggestion for health workers to provide knowledge about treatment non-pharmacological dysmenorrhoea by administering tamarind turmeric drink. Conclusion : Giving tamarind turmeric is a suitable intervention to reduce dysmenorrhea pain experienced by young women. Suggestions for health workers to provide knowledge about non-pharmacological treatment of dysmenorrhoea by giving tamarind turmeric drinks
Gambaran Pemberian Obat pada Pasien Penyakit ISPA di Puskesmas Harapan Raya Kota Pekanbaru Novia Sinata; Indah Wahyuni; Intan Ayu Deswinda; Maisarah Maisarah; Marisa Nurlita
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 6 (2024): November : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i6.822

Abstract

Acute Respiratory Infection (ARI) is a significant public health issue, particularly in areas with suboptimal environmental conditions. Community Health Centers (Puskesmas), as the primary healthcare providers, play a crucial role in managing ARI cases. This study aims to analyze the prescribing patterns of medications for ARI patients at Pekanbaru Community Health Center to evaluate whether the prescribed treatments adhere to existing guidelines and to provide recommendations. The sample for this study comprises ARI patients who sought treatment at Pekanbaru Community Health Centers in March 2024. Secondary data from the monthly report of Pekanbaru Community Health Centers in March 2024 was used as the research instrument. The collected data was analyzed by calculating the percentage of medication usage. Based on the findings from Pekanbaru Community Health Centers, the following conclusions were drawn: Most patients consuming ARI medications were female, with 80 respondents, compared to 70 males. The age group with the highest number of ARI medication consumers was [missing data]. Paracetamol 500mg was the most commonly prescribed medication at the health center."
Pengaruh Terapi Komplementer Akupressur Terhadap Kejadian Mual Muntah Pasca Pembiusan Regional Blok (Spinal Anastesi ) Diruang Pulih Rumah Sakit Umum Imelda Pekerja Indonensia Medan Satriani Hartalina Gultom; Candra Meriani Damanik; Yuni Shanti Ritonga; Syahrul Handoko Nainggolan; Ali Asman Harahap
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 6 (2024): November : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i6.824

Abstract

Postoperative nausea and vomiting is one of the common side effects of spinal anesthesia. Nausea and vomiting affect patient morbidity such as stress, discomfort, dehydration, prolonging treatment time and increasing treatment costs. This study aims to determine the effect of acupressure therapy on the incidence of nausea and vomiting after spinal anesthesia in the recovery room of the Imelda Buruh Indonesia General Hospital, Medan. This type of research is a quantitative study with a quasi-experimental research method. Data reports in the province of North Sumatra, there are 25,602 patients undergoing surgery. While at the Umim Buruh Indonesia Hospital, Medan, the data on surgical patients per January-March 2024 amounted to 666 patients, 250 patients were found to have spinal anesthesia. This study was conducted in February - June 2024 at the Imelda Buruh Indonesia General Hospital, Medan. A sample of 20 respondents was taken.: The results of the statistical test obtained an α value of 0.000 (α <0.05), thus it was concluded that there was an effect of acupressure therapy on the incidence of nausea and vomiting after spinal anesthesia at the Imelda Buruh Indonesia General Hospital, Medan. Based on the characteristics of respondents based on age, they were in the age range of 36-40 years, which was 55%, based on gender, the majority of respondents were women, which was 60%, respondents based on a history of smoking were 65%, the distribution of respondents with a history of nausea and vomiting was 55% and the majority of respondents with an incidence of nausea and vomiting was 60%. The recommendation for this study is that acupressure therapy can be applied in nursing practice so that patients are able to do it independently. For the Imelda Buruh Indonesia General Hospital, Medan, it is necessary to carry out a risk scoring of nausea and vomiting in patients before surgery to minimize the incidence of nausea and vomiting after surgery.
Evaluation of Vascular Endothelial Growth Factor, Irisin, Copeptin Levels and Some Biochemical Factors in Patients With Polycystic Ovary Syndrome in Samarra City Qaisar Mashan Abd
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 6 (2024): November : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i6.836

Abstract

This study was conducted in the laboratories of Samarra Teaching Hospital and some private laboratories in the city of Samarra in salah aldiyn  Governorate for a period from 1/8/2024 to 1/9/2024, where the study included (50) samples of women of reproductive age, ranging in age from (20-40) years, and were distributed into two groups: Patient group: (30) samples were from female patients with PCOS, Control group: (20) samples of healthy women. The pathological cases of women suffering from PCOS were confirmed after conducting clinical examinations and referring them to the specialist doctor and performing an ultrasound examination. after that, blood was taken from both groups (patients and healthy women) and separated using a centrifuge. Then the  sex hormones Luting hormone -LH, Folic stimulating hormone-FSH, and some biochemical variables, which included (Vascular endothelial growth factor-VEGF , Irisin, Copeptin). The results of the this study  showed a significant rise in each of the hormones (LH. FSH, Testosterone ,Copeptin, VEGF) and a significant low in (Irisin) in the blood serum of women infected with PCOS compered a healthy women , with a probability of P ≤ 0.05.
Hubungan Pengetahuan dan Sikap Ibu dengan Kelengkapan Imunisasi Dasar di Desa Suka Raya Kecamatan Pancur Batu Tahun 2024 Kaminya Zai; Elvipson Sinaga
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 6 (2024): November : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i6.844

Abstract

Immunization Completeness base is an immunization that must be given to children from birth so that their bodies are protected from dangerous diseases. Complete basic immunization coverage in Suka Raya Village, Pancur Batu District reached 80.7%: the low coverage of basic immunization is related to the knowledge and attitudes of mothers. This study aims to determine the relationship between maternal knowledge and attitudes and the completeness of basic immunization in infants . Data collection from primary and secondary data, data were analyzed using the chi-square test with a 95% confidence level. This type of research is analytical with a Cross Sectional approach , the population in this study were all mothers who had babies aged 9-12 months who visited Suka Raya Village, namely 42 people. The sampling technique is Total Sampling . Collection data For about complete basic immunization data analysis with Chi Square statistical test . The results of the study showed that there was a relationship between maternal knowledge and attitudes with the completeness of basic immunization with a p value for the knowledge variable of 0.003 and a p value for the attitude variable of 0.000. Then, maternal knowledge and attitudes influenced the completeness of basic immunization in infants, mothers with good knowledge and positive attitudes were more likely to complete their infants' basic immunization according to the specified schedule. It is recommended for Pancur Batu Village to further improve the provision of counseling to mothers about complete basic immunization and for health workers in Pancur Batu Village to improve maternal knowledge about the completeness of basic immunization
Pengaruh Penerapan Metode Mengajar Resiprokal Terhadap Gerak Dasar Lay Up Shoot dalam Permainan Bola Basket pada Siswa Putra SMA N 1 Tomohon Marsellino Willem Rindengan; Mesak A.S.F. Rambitan; Djoni Sunkudon
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 6 (2024): November : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i6.845

Abstract

Reciprocal method in this style students work together with their friends and give feedback to their friends, based on criteria determined by the teacher. Basketball is a sport that is competed throughout the world, basketball is one of the big ball games taught at the high school level. Basketball is a sport that uses a large ball and is used by hand and played in groups, each group consisting of two teams of 5 people each. This study aims to examine the application of reciprocal teaching style in improving the mastery of Lay Up Shoot basic movements in basketball games in male students of SMA Negeri 1 Tomohon. The instrument used in this study was a test of mastery of the basic movements of Lay Up Shoot in basketball games. The results of this study indicate that the average increase in mastery of Lay Up Shoot basic movements in basketball games in the experimental group using a reciprocal teaching style is better than the average increase in mastery of Lay Up Shoot basic movements in basketball games in the control group who did not get treatment.
Analisis Determinan Perilaku Keselamatan Berkendara (Safety Riding) pada Ojek Online (Maxim) di Pangkalan Ojek Motor Jl. Untung Suropati Kota Samarinda Dwi Andre Gustian Prayugo; Nino Adib Chifdillah; Emelia Tonapa
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 6 (2024): November : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i6.846

Abstract

Traffic and road accidents are considered one of the leading causes of death among children and adolescents aged 5-29 years. This study aims to analyze the relationship between age, education level, driving experience, and knowledge with safety riding behavior among motorcycle taxi riders at the MAXIM Online Ojek Base on Jl. Untung Suropati, Samarinda City. The research method used in this study is a quantitative research approach. This type of research is observational-analytic with a cross-sectional design. The sampling technique used is purposive sampling, where samples are selected based on criteria predetermined by the researcher. The total sample consists of 37 individuals, determined using the total sampling technique. Data analysis was conducted using the Chi-Square test. The results show that there is a relationship between age and knowledge with respondents' safety riding behavior. However, there is no relationship between driving experience and education level with respondents' safety riding behavior. In conclusion, it is recommended that motorcycle taxi riders improve their knowledge of proper safety riding practices.

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