cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Windadari Murni Hartini
Contact Email
garuda@apji.org
Phone
+6288215137076
Journal Mail Official
bagusharinugroho@arikesi.or.id
Editorial Address
Perum Cluster G11 Nomor 17 Jl. Plamongan Indah, Kadungwringin, Pedurungan, Semarang, Provinsi Jawa Tengah, 50195
Location
Kota semarang,
Jawa tengah
INDONESIA
Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan
Published by Asosiasi Riset Ilmu Kesehatan Indonesia
ISSN : 3031013X     EISSN : 30310148     DOI : 10.61132
Core Subject : Health,
Health Professions Nursing Public Health
Organisasi Farmasi, Kedokteran, Kimia Organik Sintetis, Kimia Alam, Biokimia, Analisis Kimia, Kimia Fisika, Biologi, Mikrobiologi, Jaringan Budaya, Botani dan Hewan terkait Produk Farmasi, Keperawatan, Kebidanan, Analis Kesehatan, Gizi dan Kesehatan Masyarakat.
Arjuna Subject : Profesi Kesehatan - Farmasi
Articles 378 Documents
 23   24   25   26   27 
Isolasi dan Karakterisasi Minyak Asiri Jeruk Nipis menggunakan GC-MS dan Aktivitasnya terhadap Bakteri Patogen Kulit Nastiti Nur Indriyani; Adi Susanto
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 1 (2025): January: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i1.925

Abstract

In the fruit processing industry, peel is one of the main by-products. Non-edible portions of fruit are likewise seen as waste and are frequently thrown out into the environment. Nowadays, one of the main sources used by the pharmaceutical sector to isolate and extract secondary metabolites is fruit peels. Many applications known for lime peel, especially for antibacterial. This study focuses on the isolation, chemical composition characterization, and antibacterial activity on skin pathogenic bacteria of lime peel essential oil (LPEO). LPEO were isolated using steam distillation and characterized by GC/MS. A total of 24 components were identified. The major constituents of the LPEO were d-limonene (40.24%), β-terpinene (15.68%), sabinene (13.15%), citral (3.41%), α-Terpineol (3.40%), and terpinene-4-ol (2.94%). The antibacterial activity was determined using the Kirby-Baurer method against several bacteria that can cause skin infections. The antibacterial activity of LPEO against Escherichia coli, Staphylococcus aureus, Staphylococcus epidermidis dan Propionicbacterium acne is confirmed. LPEO showed varied levels of antibacteria activity against the gram positive and gram negative bacteria. Zone of inhibition (ZOI) in millimetres was used to measure the antibacterial activity, and amoxicillin was used as a control.
Effectiveness Study of BPOM’s Assistance for MSMEs in Natural Medicine and Cosmetics to Obtain Distribution Permits Mohamad Kashuri
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 1 (2025): January: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i1.945

Abstract

This study evaluates the effectiveness of BPOM’s mentoring programs for Micro, Small, and Medium Enterprises (MSMEs) in the natural medicine and cosmetics sectors in navigating complex regulatory requirements to obtain product licenses. Despite the strategic role of MSMEs in supporting Indonesia’s economy, regulatory compliance remains a significant challenge, particularly due to limited resources and market access. Previous studies have highlighted the need for adaptive regulatory approaches and mentoring programs, but gaps remain in evaluating their long-term impact and inclusivity. This study offers novelty by analyzing the program’s effectiveness across diverse demographic and educational backgrounds, providing evidence-based insights into its impact. Using a descriptive quantitative approach, data were collected through surveys involving 35 MSME participants from the “Rembuk UMKM” event. The Likert-scale questionnaire assessed regulatory understanding, program effectiveness, and its impact on license readiness. Data were analyzed using descriptive statistics, generating insights into participant perceptions. The findings show that the mentoring program is most effective among younger participants (aged 18–25 years), scoring 4.53, while maintaining high effectiveness scores across all age groups. Educational background analysis revealed the highest scores (5.00) from vocational high school (SMK) and master’s (S2) participants, highlighting the program’s inclusivity and adaptability. However, team competence scored relatively lower (4.26), indicating the need for continuous capacity building. The study concludes that BPOM’s mentoring programs significantly enhance MSME compliance and build long-term trust, with strategic recommendations for continuous training, technology-based module development, regional collaborations, and structured feedback mechanisms. These initiatives aim to strengthen program relevance and sustainability, supporting MSMEs in achieving regulatory compliance and contributing to national economic growth.
CT scan assessment of Olfactory Fossa in Kirkuk adult population prior to sinus surgery Hussein, Karim Mahmood
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 1 (2025): January: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i1.948

Abstract

Background: The fovea ethmoidalis and the lateral lamella of the cribriform plate of the ethmoid bone are the parts of the skull base that are most vulnerable to iatrogenic problems during functional endoscopic sinus surgery. The vertical height of the cribriform plate's lateral lamella, which is divided into three groups based on Keros types. According to the Keros, The likelihood of iatrogenic injury and issues increases with the cribriform plate's lateral lamella height. Aim of the study: The aim of this study is to assess the discrepancies in the ethmoid roof elevation (the depth of the olfactory fossa) amongst the adult Kirkuk population using multi-detector computed tomography. Patients and methods: 160 persons who were referred for a CT scan to evaluate their paranasal sinuses participated in the study. Participants in this study were not allowed to have any pathological abnormalities affecting the ethmoid roof. According to the Keros classification, which was split into three groups (Keros I from 1 to 3 mm, and from 4 to 7 mm considered Keros II, while Keros III should be from 8 mm and more), the vertical height of the lateral lamella of the cribriform plate was measured using the coronal portion of a CT image. Results: The patients' average age was 35.25 ±14.16 years. The range of the left lateral lamella height is 2.1 to 10.0 mm, and the range of the right lateral lamella height is 2.0 to 9.9 mm. Of these, 43.75% had Keros type I, 55% had Keros type II, and 1.25% had Keros type III. Conclusion: Keros type II was present in the majority (about 55%) of the adult population in that was studied while Keros type I was (about 43.75%). However, just (about 1.25%) of the adults population in the sample had Keros type III.
Study the Lipoxygenase Enzyme Activity on Patients With Thalassemia in Kirkuk Governorate Wisam Sbhan Khalf Mohamed Aljumaily; Khalaf Naeef Mohamed
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 1 (2025): January: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i1.968

Abstract

This study was conducted at the Thalassemia Center of Azadi Educational Hospital, Kirkuk Health Directorate, Iraq, from June 1, 2024, to October 1, 2024. The study sample included 75 individuals, both males and females, aged between 4 and 67 years, divided into two groups: the first group comprised 50 thalassemia patients, while the control group included 25 healthy individuals. The results indicated a significant effect of thalassemia on the studied variables, as the disease led to increased levels of white blood cells, erythrocyte sedimentation rate, total iron-binding capacity, malondialdehyde, iron concentration, and lipoxygenase enzyme, recording values of 10.9 × 103 cells/mL, 25.36%, 321.84 µg/dL, 721.12 mmol/L, 2788.9 ng/dL, and 226.2 IU/L, respectively. In contrast, thalassemia reduced hemoglobin levels to 8.57 g/L. The gender category significantly affected both malondialdehyde and iron concentrations, while the age category significantly impacted white blood cell levels, total iron-binding capacity, serum iron, and lipoxygenase enzyme. Among the interactions, the most influential factor was found in the group of female patients over 30 years old, who recorded the highest significant concentrations of white blood cells and malondialdehyde, reaching 12.26 × 103 cells/mL and 1090 mmol/L. Conversely, female patients under 15 years showed the highest significant averages for the percentage of erythrocyte sedimentation rate and iron concentration, at 28% and 3270 ng/dL, respectively. Meanwhile, female patients aged 15-30 years exhibited the highest significant concentrations for total iron-binding capacity and lipoxygenase enzyme, at 361.8 µg/dL and 234 IU/L, respectively. Male patients aged 15-30 years recorded the lowest significant hemoglobin concentration, which was 7.33 g/L.
Analisis Pengetahuan Penggunaan Obat Paten dan Obat Generik di Desa Sukorejo Kecamatan Ulujami Kabupaten Pemalang Amanda Dwijayanti; Musa Fitri Fatkhiyah
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 1 (2025): January: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i1.973

Abstract

Patented drugs are a type of drug that has just been discovered and has a certain patent period based on its type. This drug is designed to provide convenience through innovations such as practical packaging, better taste, and syrup that is not bitter due to the use of micro particles. Technologies such as slow-release tablets or sugar coatings also reduce side effects in the stomach, making them safer to use. In addition, this innovation can overcome other obstacles, such as avoiding alcohol solvents that are not in accordance with some religious beliefs. On the other hand, generic drugs still meet pharmacopoeial requirements and have gone through a good drug manufacturing process (CPOB), with strict supervision from the Food and Drug Supervisory Agency (BPOM). This study aims to determine the level of knowledge of the people of Sukorejo Village about patented and generic drugs. The type of research used is descriptive, using a questionnaire as a data collection tool. The sample consisted of 100 people selected through a simple random sampling technique, where each element of the population has an equal chance of being selected. Percentage analysis was used to evaluate the results of the study. The data shows that 49% of respondents have good knowledge of patented and generic drugs, while 23% have sufficient knowledge. These results indicate that the majority of the community already understands the differences between the two types of drugs.
Review Of "Chasing Resistance: New Antibiotics For A Changing Landscape Eman Hamza Mohammed
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 4 (2024): Juli : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i4.989

Abstract

Antimicrobial resistance (AMR) is an age-old biological phenomenon, as evidenced by its evolutionary history and abundance of environmental immunity Antibiotics used by humans contributes to resistance to acquired disease, a public health issue that drives the selection of resistance genes. A.M.R. One of the most important strategies to combat AMR is the search for new antibiotics. During the 1980s, existing products were either enhanced or modified in antibiotics currently on the market. The World Health Organization (WHO) warns of limited new candidates and highly characterizes the current pipeline. After careful analysis of preclinical and therapeutic pipelines, it seems expected that very few new antibiotics will enter the market in the coming years . Most of these candidates do not meet the new standards required to adequately address the growing threat of antimicrobial resistance (AMR).The key principles to cope with the rapidly emerging AMR are diversity and innovation which are done. R&D efforts should address new antibiotic resistance. Although there is promising potential to change the dynamics between the spread of AMR, antibiotic reserves, and meeting new lead standards, we examine the historical context and challenges associated with drug a kills bacteria detection, and various other processes. Let us describe the proposed methods of revitalizing the pipeline.
The Impact of the adeE and adeY Genes on the Antibiotic Resistance Mechanisms of Acinetobacter baumannii Rawaa M. Mohammed
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 3 (2025): May: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i3.1286

Abstract

Current study identified Acinetobacter baumannii isolates from burn wound samples using biochemical andmolecular techniques focusing on the rpoB gene. All isolates showed variable virulence factors, includingbiofilm formation (100%), gelatinase activity (90%), and mannose-resistant hemagglutination (72%). Antibioticsusceptibility testing revealed high resistance rates to Rifampin (96%), Tetracycline (92%), and third-generation cephalosporins such as Cefotaxime (73%) and Ceftriaxone (81%). Lower resistance rates wereobserved for Levofloxacin (31%) and Gatifloxacin (27%), suggesting potential effectiveness.PCR analysis confirmed the presence of AdeE and AdeY efflux pump genes in several isolates. However,statistical analysis, including Chi-square/Fisher’s tests and t-tests, demonstrated no significant correlationbetween the presence of these genes and antibiotic resistance patterns (p > 0.05). This indicates that whileefflux pump genes are present, their presence alone does not predict antibiotic resistance in the tested isolates.The findings highlight the complex mechanisms of resistance in A. baumannii and the need for continuedsurveillance and molecular diagnostics to guide effective infection control.
Pengetahuan Pasien Terhadap Adverse Drug Reactions (ADRs) Penggunaan Obat Antibiotik Beta-Laktam di RSUD Bendan Tahun 2024 Ghiska Ma’alia Yusuf; Musa Fitri Fatkhiya
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 3 (2025): May: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i3.1295

Abstract

Knowledge is the result of the process of understanding and recognizing something obtained through sensing an object. Beta-lactam antibiotics are a type of broad-spectrum antibiotic commonly used to treat bacterial infections, but their use still has the potential to cause side effects in the form of Adverse Drug Reactions (ADRs). This study aims to assess the level of patient knowledge regarding ADRs due to the use of beta-lactam antibiotics at Bendan Pekalongan Regional Hospital in 2024. This study used a prospective correlation design with a non-experimental approach. A total of 29 outpatients taking beta-lactam antibiotics were sampled, selected using a purposive sampling technique. Data were collected through questionnaires, medical records, and analyzed descriptively using Microsoft Excel. The results showed that 41% of respondents had low knowledge regarding ADRs, 28% had sufficient knowledge, and 31% had good knowledge. These findings indicate the need for more intensive education regarding the risks of ADRs in order to improve the safety of antibiotic use.
Perbandingan Efektivitas Paracetamol vs Ibuprofen dalam Manajemen Demam Dewasa: Analisis Berbasis Data Real-World Nur Amalinda; Haryanto Haryanto
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 3 (2025): May: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i3.1300

Abstract

Fever is the body's response to infection or inflammation, which often indicates a certain medical condition. One common treatment for fever is the use of antipyretic drugs. The purpose of this study was to evaluate the effectiveness of antipyretic drugs in lowering body temperature in adult patients with fever. The method used was a clinical trial with a randomized controlled trial (RCT) design, involving 100 adult patients with fever ≥38°C. Patients were divided into two groups: the group receiving antipyretic drugs (paracetamol) and the placebo group. Body temperature measurements were taken every 2 hours for 24 hours after drug administration. The results showed that the group receiving antipyretic drugs experienced a significant decrease in body temperature compared to the placebo group (p <0.05). The side effects that appeared were relatively mild and not dangerous..
Gambaran Tingkat Pengetahuan Pasien Diabetes Tentang Penggunaan Obat Herbal Manfaat, Resiko, dan Potensi Interaksi dengan Obat Konvensional di Puskesmas Kebondalem Kabupaten Pemalang Retno Anisa; Nila Oktaviani
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 3 (2025): May: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i3.1302

Abstract

Diabetes mellitus is a chronic disease that requires proper management, including the use of conventional and alternative medicines such as herbal medicines. Patient knowledge about the benefits, risks, and potential interactions of herbal medicines with conventional medicines is very important to prevent complications. Objective This study aims to describe the level of knowledge of diabetes patients about the use of herbal medicines, including the benefits, risks, and interactions with conventional medicines at the Kebondalem Health Center, Pemalang Regency. This study uses descriptive observational analytic Data were collected through questionnaires distributed to diabetes patients who were treated at the Kebondalem Health Center. Data analysis was carried out quantitatively with percentages to measure the level of patient knowledge.

Page 25 of 38 | Total Record : 378

 23   24   25   26   27 

Filter by Year

2023 2026


Reset
Filter By Issues
All Issue Vol. 4 No. 2 (2026): Maret: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 1 (2026): Januari: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 6 (2025): November: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 5 (2025): September : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 4 (2025): July: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 3 (2025): May: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 2 (2025): March: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 1 (2025): January: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 6 (2024): November : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 5 (2024): September : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 4 (2024): Juli : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 3 (2024): May : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 2 (2024): March : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 1 (2024): Januari : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 1 No. 6 (2023): November : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan More Issue