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Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan
Published by Asosiasi Riset Ilmu Kesehatan Indonesia
ISSN : 3031013X     EISSN : 30310148     DOI : 10.61132
Core Subject : Health,
Health Professions Nursing Public Health
Organisasi Farmasi, Kedokteran, Kimia Organik Sintetis, Kimia Alam, Biokimia, Analisis Kimia, Kimia Fisika, Biologi, Mikrobiologi, Jaringan Budaya, Botani dan Hewan terkait Produk Farmasi, Keperawatan, Kebidanan, Analis Kesehatan, Gizi dan Kesehatan Masyarakat.
Arjuna Subject : Profesi Kesehatan - Farmasi
Articles 378 Documents
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Multidimensi Pengemas Obat : Inovasi, Informasi, dan Perlindungan Konsumen Mahabatul Hasanah; Siti Fatimatuzzahra; Nor Latifah
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 4 (2025): July: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i4.1436

Abstract

Drug packaging not only serves as a protective barrier for pharmaceutical products but also functions as a strategic element in conveying information and ensuring consumer rights. This study is a literature review of five journals that discuss packaging innovation, legal aspects of labeling, consumer protection, and packaging design from both technological and regulatory perspectives. The aim of this study is to compare the dimensions of innovation, information, and protection in drug packaging. A narrative review method with a qualitative descriptive approach was used. The results show that innovations such as the use of adsorbent plastic and efficiency in packaging systems significantly affect product stability and production speed. Meanwhile, the inclusion of composition details and halal labeling on packaging serves as a form of consumer protection from health risks and rights violations. It is concluded that a multidimensional approach to drug packaging is essential in creating a pharmaceutical distribution system that is efficient, safe, and ethical.
Inventarisasi dan Potensi Tumbuhan Berkhasiat Obat di Desa Selilau, Aru Tengah, Maluku Sepbrilla Ananda K; Mulia Maharani; Yumaisaroh Chudaibiyah; Maria Delsiana Ndun; Jihan Fahiroh Nur Arifin; Ryan Satria Pranata; Rusdiana Tri Septiarini; Retno Wulan Devitri; Ivan Charles Seran Klau
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 4 (2025): July: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i4.1440

Abstract

Indonesia has around 3,500 species of therapeutic plants, one of which is utilized by the individuals of Selilau Town, Aru Islands Rule, Maluku Area.. This study aims to examine 15 types of medicinal plants that are used traditionally, including plant parts, properties, active compound content, and pharmacological activity based on scientific literature from the last 10 years. This survey points to recognize species of restorative plants commonly utilized in neighborhood conventional medication, look at the plant parts utilized, handling strategies, and maladies treated based on neighborhood experiences and to survey logical writing to decide the dynamic compound substance and pharmacological movement of each distinguished plant. The comes about of the think about appeared that the foremost broadly utilized plant is the leaf portion. Some of them are: Momordica charantia (bitter melon) for cough; Urena lobata (pulutan) to smooth postpartum blood; Morinda citrifolia (mengkudu) for broken bones; Erythrina variegata (dadap) for body recovery; Myrmecodia pendens (ant nest) for swelling and beriberi; and Carica papaya (papaya) for malaria. Other plants such as Manihot esculenta, Tradescantia spathacea, Graptophyllum pictum, Hemigraphis alternata, Mimosa pudica, Jatropha curcas, Psidium guajava, Nypa fruticans, and Stachytarpheta jamaicensis are also used for various health complaints. Active compounds such as flavonoids, alkaloids, tannins, and saponins support pharmacological activities such as anti-inflammatory, antioxidant, antipyretic, gastroprotective, and immunostimulant. This study emphasizes the importance of documenting traditional knowledge as an effort to preserve and develop local wisdom-based medicines.
Prolactin as a Potential Biomarker of Glycemic Control in Women with Type 2 Diabetes Mellitus Hashim Abed Abass; Salih Mahdi Salih
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 4 (2025): July: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i4.1441

Abstract

Prolactin, a hormone primarily known for its important role in lactation and reproductive function have recently been implicated in metabolic-processes including glucose regulation. This study aims to investigation the relationship between serum prolactin levels and markers of glucose metabolism—specifically HbA1c and fasting blood glucose (FBG)—in women with T2DM. A cross sectional study was conducted on 100 adult female patients with T2DM, aged 35–50 years. Participants were classified based on HbA1c into three groups: good (≤7.0%), moderate (7.1–8.5%), and poor (≥8.6%) glycemic control. They were also stratified into low, normal, and high prolactin level groups. Serum prolactin was measured by ELISA, HbA1c by HPLC, and FBG using an automated analyzer. Statistical analysis was performed with significance at p ≤ 0.05. Although prolactin levels tended to increase with worsening HbA1c, the difference among HbA1c groups was not statistically significant. However, when stratified by prolactin levels, women in the high prolactin group had significantly higher HbA1c (7.38 ± 1.07%) and FBG (163.21 ± 25.23 mg/dL) compared to those in the low prolactin group (HbA1c: 6.82 ± 0.91%, FBG: 149.22 ± 22.24 mg/dL; p = 0.041 and p = 0.040, respectively). Elevated serum prolactin levels may be associated with poorer glycemic control in women with T2DM. These results showing the potential-role of prolactin hormone as a supplementary test in measuring glucose metabolism.
Glucose Sensing Using Hydrogel By Incorporating Phenylboronic Acid Groups Nadia Baqer Hussein
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 4 (2025): July: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i4.1444

Abstract

Background: Research of glucose detection is important in diabetes management and biosensor development. Taking into account the large amount of water retention, the biocompatibility of hydrogels makes them ideal candidates for glucose detection. The PBA groups, when grafted to hydrogel matrices, improve the glucose-related response of the hydrogels significantly. Objective: To create a novel PBA (phenylboronic acid) holographic glucose sensor, MAAm-co-4VPBA, for uninterrupted monitoring of blood glucose levels, which demonstrates the first successful glucose measurement in whole blood using PBA sensors. Methods: Methylacrylamide (MAAm) was copolymerized with 4-vinyl phenyl boronic acid (4-VPBA) by means of free radical polymerization employing 1,6-hexanedioldiacrylate (HDODA) as a crosslinker and the photoinitiator 1-hydroxycyclohexyl phenyl ketone. The responsive glucose behavior of the resulting polymer was characterized in terms of swelling dynamics, ex vivo flow tests, and error grid analysis mechanisms. Results: The MAAm-co-4VPBA polymer exhibits reversible glucose binding via PBA-diol interactions that allow complexation at different pH and concentration levels. Modulation of the responsive elements of the microcapsules by hydrophobic PBA and hydrophilic MAAm units yields maximum swelling and shrinking dynamics at 37 trail degrees. The sensor successfully detected glucose in opaque biological fluids, blood plasma, without any interference from antibiotics or other therapeutics or endogenous compounds. Ex vivo tests showed real-time glucose monitoring without hysteresis. Most importantly, this work is the first to report the use of PBA-based sensors in whole blood for measuring glucose. Conclusion: The MAAm-co-4VPBA holographic sensor possesses outstanding features such as accurate records and strong resistance to chemicals and slow response to detection, confirming its effectiveness in continuous glucose monitoring. Moreover, the ability to operate in the real world enables the aid in clinical diagnosis of diabetes.
The Hubungan Pengetahuan, Sikap, dan Praktik (KAP) Masyarakat terhadap Pengelolaan Sampah Rumah Tangga Berbasis 3R Tri Hapsari, Azkiya; Suherman Jaksa
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 4 (2025): July: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i4.1490

Abstract

Household waste is one of the major contributors to environmental problems. Waste management based on the 3Rs is an important strategy in reducing negative impacts on health and ecosystems. This study aims to review the literature on the relationship between knowledge, attitudes, and practices of the community in managing household waste based on the 3R principles. The method used was a literature study by collecting literature from Google Scholar and Science Direct. The results showed that good knowledge encourages positive attitudes and more effective waste management practices. Education, especially to housewives, is proven to increase awareness and active participation in sorting and processing waste. Successful waste management requires active community involvement, infrastructure support, and ongoing mentoring. In conclusion, the strong relationship between knowledge, attitude and practice shows the importance of an integrated approach to household waste management based on the 3R principles to create a clean, healthy and sustainable environment. The contribution of this research to science is through the review of various field studies from a number of regions in Indonesia, and emphasizes the urgency of community-based education, especially for strategic groups such as housewives. Educational efforts to increase active participation and awareness of the 3R principles can be used as a reference in designing intervention programs by both the government and non-governmental organizations.  
An Investigation into the Antioxidant Effects of Frankincense Aqueous Extract and its Influence on Acetyl Cholinesterase in Alzheimer's patients in Diwaniyah Meaad Nasser Hussein; Shaimaa Adnan; Ali Noory Fajer
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 4 (2025): July: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i4.1494

Abstract

The present study aims to prepare the aqueous extract of the frankincense plant and then identify the most important biologically active substances in it, and study the effect of these substances against free radicals (2,2-diphenylpicrylhydrazyl (DPPH)) and Total Antioxidant Capacity. Then the effect of extract was tested on the blood serum of Alzheimer's patients in the nursing home in Diwaniyah Governorate, where 30 people were taken. 10 of them were healthy and were considered a positive control groupG1, and 20 of them were Alzheimer's patients, where 10 of them were considered a negative control groupG2, and the other 10 Alzheimer's patients had their serum treated with the extract of frankincenseG3. The effect of the extract on malondialdehyde and acetylcholinesterase enzyme was tested. The current study showed that extract contains biologically active substances such as (Flavonoids, Phenols, Tannins Triterpenoids, Steroids and Saponins) and these substances had an effective effect in inhibiting the radical (DPPH) where the inhibition rate reached 88% at (250mg/ml) and Total Antioxidant Capacity was (8.8*103 µmol/L) at the same concentration. That results also showed the significant rise in the concentration malonaldehyde in Alzheimer’s patients (G2, G3) when compared with G1. When the G3 was treated with the aqueous extract, a decrease in the concentration of malonaldehyde (3.23µml/l) was observed. The significant reduction in the Activity of the Acetylcholinesterase enzyme (3.97U/ml) was also observed in the (G3) as compared with(G2) (12.297U/ml). This is due to the biologically active substances in the extract, which indicates the possibility of using this extract to treat Alzheimer's patients in the future.
Applications of Nanotechnology in Green Chemistry Rawya Z Al-khayat; Ammar Gh. Ameen AL-dabbagh; Seba S. Mohammed; Raya Doraid Mohammed
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 4 (2025): July: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i4.1495

Abstract

Nanotechnology is the science of present and future, it has different physical, chemical, biological preparation methods, it has many applications in green chemistry, agriculture, industry, electronics, environmental pollution. Gold, silver, zinc oxide and titanium dioxide nanoparticles are among most important particles that have many advantages and uses.
Uji Stabilitas Obat Sediaan Tablet: Prinsip, Pedoman ICH Q1, dan Parameter Kritis Jannatun Nisa; Nicky Saputra; Nor Latifah
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 4 (2025): July: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i4.1507

Abstract

This article provides a comprehensive review of drug stability testing, specifically focusing on tablet dosage forms. It elucidates the fundamental principles, the critical role of ICH Q1 guidelines, and essential parameters evaluated during stability studies, including physical, chemical, and microbiological aspects. The discussion covers various types of stability studies, standardized storage conditions, and the interpretation of results for determining shelf life and ensuring product quality. Relevant case studies on tablet stability are also integrated to illustrate practical applications. This review aims to provide a structured overview of stability testing methodologies and their significance in pharmaceutical development and quality assurance.
Penanganan Fisioterapi pada Kasus PPOK Amalia Ferina Anggraeni; Adnan Faris Naufal; Mulatsih Nita Utami
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 4 (2025): July: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i4.1510

Abstract

COPD is a condition characterized by airflow obstruction that cannot be completely corrected. This limitation generally worsens over time and is associated with abnormal permeability to noxious particles or gases, resulting in narrowing of the airways, increased mucus secretion, and changes in the vascular system. The increase in chest expansion capacity is caused by the activity of respiratory muscle contraction. The activity of the respiratory muscles plays a role in chest expansion, which also affects lung growth. It is stated that the strength of the respiratory muscles decreases with age. Loss of intercostal muscle mass and strength are factors that reduce the ability of chest wall presence or development. This study used a case report design research method. Physiotherapy management for COPD is increasingly focused on exercise-based rehabilitation, both in outpatient and inpatient settings. Some therapies such as breathing exercises, thoracic expansion exercises and muscle release.
Hubungan Antara Pengelolaan Sampah Rumah Tangga dan Kualitas Kesehatan Lingkungan Permukiman Ahda Ahda; Ernyasih Ernyasih
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 3 No. 4 (2025): July: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v3i4.1516

Abstract

Household waste management is an important part of maintaining environmental quality. This article is a literature review that aims to identify and analyze the relationship between household waste management and its impact on environmental quality. The purpose of this study is to gain a better understanding of the extent to which household waste management behaviors and systems can affect environmental conditions and public health. The method used is a systematic literature review of various scientific journals, research reports, and policy documents published in the last ten years. Data sources were taken from academic databases such as Google Scholar, ScienceDirect, and PubMed, with a focus on studies discussing aspects of waste management, sanitation, and health impacts in residential environments. The results of the study show that poor urban waste management, such as littering and open burning, is associated with an increase in environmental diseases. Conversely, good management systems, such as regular sorting and transportation, have a positive impact on the cleanliness and health of the residential environment. Conclusion Good household waste management plays an important role in maintaining a healthy living environment. Organized and participatory practices can reduce the risk of disease and create a clean, healthy, and sustainable environment for communities.

Page 28 of 38 | Total Record : 378

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