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Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan
Published by Asosiasi Riset Ilmu Kesehatan Indonesia
ISSN : 3031013X     EISSN : 30310148     DOI : 10.61132
Core Subject : Health,
Health Professions Nursing Public Health
Organisasi Farmasi, Kedokteran, Kimia Organik Sintetis, Kimia Alam, Biokimia, Analisis Kimia, Kimia Fisika, Biologi, Mikrobiologi, Jaringan Budaya, Botani dan Hewan terkait Produk Farmasi, Keperawatan, Kebidanan, Analis Kesehatan, Gizi dan Kesehatan Masyarakat.
Arjuna Subject : Profesi Kesehatan - Farmasi
Articles 378 Documents
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Formulasi Dan Uji Aktivitas Antibakteri Sediaan Krim Ekstrak Etanol Kulit Buah Manggis (Garcinia Mangostana Linn.) Terhadap Bakteri Propionibacterium Acnes ATCC 1335 Lydia Fitriana; Tiara Ajeng L; Anita Dwi Septiarini S; Danang Raharjo
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 1 (2024): Januari : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i2.197

Abstract

The skin is the widest organ that makes up the human body which is the outermost and covers the entire surface of the body. The outermost location causes the skin to receive stimulation for the first time such as touch stimulation, pain, or bad influences from outside. This causes the skin to stretch due to disease. One of the most common skin diseases suffered by people is acne. Acne occurs generally triggered by the bacterium Propionibacterium acnes (gram positive bacteria). Effective acne treatment can use antibiotics, but inappropriate use of antibiotics can lead to resistance. Therefore it is necessary to have alternative therapies from plants that have the potential as antibacterial. One of the natural ingredients from plants that have antibacterial properties is mangosteen (Garcinia mangostana Linn.)This research was conducted using a descriptive experimental method with the aim of knowing the presence of antibacterial activity in cream preparations of ethanol extract of mangosteen rind (Garcinia mangostana Linn.) against Propionibacterium acnes bacteria as seen from the inhibition of bacteria with varying concentrations of 10%, 15% and 25% by using paper disc diffusion method and solid liquid dilution method. The positive control used clindamycin cream and the negative control used 1% DMSO. Analysis of the diameter of the inhibition data was carried out using the One Way ANOVA test. The preparation formulation that has the largest diameter in the diffusion test is F3 with a concentration of 25% with an average inhibition of 6.36 in the medium category. The MIC and KBM values in the dilution method were at a concentration of 12.5%. The results of a normally distributed One Way ANOVA are measured with a value (P> 0.05). Mangosteen peel extract (Garcinia mangostana Linn.) has antibacterial activity against Propionibacterium acnes bacteria.
Analisis Faktor Yang Mempengaruhi Respon Pengobatan TB Paru Lini Pertama Di RSUD Tugurejo Semarang Nadya Rachma Fachriah; Afiana Rohmani; Setyoko Setyoko
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 2 (2024): March : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i2.202

Abstract

One of the infectious diseases that still poses a threat to the world is tuberculosis (TB). When a person is diagnosed with tuberculosis, anti-tuberculosis drugs (ATD) should be administered as soon as possible as part of their treatment. Treatment for tuberculosis may be impacted by a number of factors, including age, gender, comorbidities, and nutritional status. The purpose of this study is to ascertain how age, gender, nutritional status, and comorbidities relate to the response of patients receiving first-line pulmonary tuberculosis treatment at Tugurejo Hospital Semarang using Anti Tuberculosis Drugs category one. This kind of cross-sectional, analytical observational research is being conducted. Response to first-line pulmonary tuberculosis treatment was the dependent variable, and independent variables included age, gender, nutritional status, and comorbidities. 50 patients in all were selected as samples from Tugurejo Regional Public Hospital's medical files. Statistical analysis used the chi-square test for bivariate and the logistic regression test for multivariate. The analysis's findings demonstrated a significant relationship (p-value 0.001) between nutritional status and treatment response, as well as a significant relationship (p value 0.005) between comorbidities and treatment response. However, there was no significant correlation found between the age and gender variables (p values of 0.617 and 0.425). The results of the logistic regression showed that comorbidities and nutritional status had significant results with the OR value of comorbidities (OR 13,622, 95% CI 2.207-84.075, p= 0.005) and nutritional status (OR 7.208, 95% CI 1.783-29.138, P=0.006). There is a noteworthy correlation between the response to first-line pulmonary tuberculosis treatment and nutritional status and comorbidities at Tugurejo Hospital Semarang. At Tugurejo Hospital Semarang, there is a noteworthy correlation between the response to first-line pulmonary tuberculosis treatment and nutritional status and comorbidities.
Perlindungan Konsumen terhadap Peredaran Obat Secara Online Tanpa Izin Edar Vina Aprilia; Nur Lailatul Maghfiroh; Salsabila Dhiya Atik; Nabyla Qutrun Nada; Alfan Hermawan; Muhammad Rizky Imami; Moh Basri Firdaus F.N7; Herdiansyah Rusman Hadi; Ainun Nur Cahyani; Marthy Meliana A.J; Dewi Rahmawati
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 2 (2024): March : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i2.213

Abstract

Health is the main capital for the growth of the nation's life. The development of trade is currently experiencing very rapidprogress, which occurs not only in the goods traded but also in the buying and selling transactions themselves. One very important component of health is the availability of medicines as part of public health services. This research aims to find out about the distribution of drugs without a distribution permit and consumer protection in terms of monitoring and taking action against drugs without a distribution permit that are sold online by the Food and Drug Supervisory Agency and the Ministry of Communication and Information. The results of the research show that the Food and Drug Supervisory Agency has made various efforts to protect the public from drugs without distribution permits that are sold online, in handling the circulation of drugs sold online, the Food and Drug Supervisory Agency collaborates with Interpol and other government agencies such as the Ministry of Communication and Informatics carries out Operation Pangea. In this operation, the Food and Drug Supervisory Agency will list websites and social media accounts that promote and market drugs without a distribution permit to be submitted to the Ministry of Communication and Information for blocking. A distribution permit is preventive supervision as a form of protection for consumers carried out by the Food and Drug Supervisory Agency before the drug circulates in the community. So it is reasonable to suspect that if a drug does not have a distribution permit, the drug has not been tested for safety, efficacy and quality aspects.
Pengaruh Pendidikan Kesehatan Seks Remaja Melalui Media Leafleat Dan Tanya Jawab Terhadap Perubahan Pengetahuan Pada Santriwati Di Pondok Pesantren Al Mukmin Sukoharjo Munaaya Fitriyya; Wijayanti Wijayanti
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 1 (2024): Januari : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i1.222

Abstract

The importance of adolescent sexual health education in Islamic boarding schools goes beyond being a preventive measure for reproductive health issues. It also aims to shape a balanced understanding in accordance with religious values. In this context, Al Mukmin Islamic Boarding School in Sukoharjo strives to make a positive contribution to the development and understanding of female students regarding sexual health while reinforcing the moral and religious values instilled in the boarding school. Through leaflets and Q&A sessions, it is hoped that female students can gain better knowledge about adolescent sexual health, including some aspects such as reproduction, self-protection, relevant religious norms, and the importance of open communication with parents or guardians. The using of these media is expected to have a positive impact on changing the knowledge of female students, subsequently influencing their behaviors and decisions related to sexual health. This study is an experimental research with a one-group pre-post test method. To assess the impact of adolescent sexual health education is through leaflets and Q&A sessions then tested by Wilcoxon test. This test is utilized due to the non-normal distribution of the research data. Non-probability sampling (quota sampling method) is employed for sample selection. The population of this study consists of 56 female students from class X at Al Mukmin Islamic Boarding School in Sukoharjo.There is an increase in the knowledge scores of female students after receiving adolescent sexual health education through leaflets and Q&A sessions. The average knowledge score of female students before the education (pretest) was 13.30 ± 14.27 with a median of 14.00 and a score range of 8. After the education (posttest), the average knowledge score increased to 19.56 ± 19.83 with a median of 20.00 and a score range of 2. This indicates an improvement in the knowledge of class X female students at Al Mukmin Islamic Boarding School after receive information or education about adolescent sexual health. The adolescent sexual health education provided has a significant impact on improving knowledge, or it could be said that adolescent sexual health education can improve female students' thinking abilities.
Dukungan Keluarga dengan Kelancaran Asi Pada Ibu Menyusui di Wilayah Kerja Puskesma Kuta Baro Aceh Besar Khaira Rizki; Nurul Amna; Nurliza Nurliza
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 1 No. 6 (2023): November : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v1i6.229

Abstract

Mother's milk (ASI) is rich in nutrients and is the key to baby's health. Breast milk is the best food that babies aged 0-6 months need for optimal growth and development, increasing body resistance, protecting against infection, forming a healthy digestive system and increasing intelligence. The aim of this research is to determine the relationship between family support and smooth breastfeeding for breastfeeding mothers in the Kuta Baro Aceh Besar Community Health Center working area. This research is quantitative with an analytical design using a cross-sectional study method. The population in this study were all breastfeeding mothers who had babies aged 0-6 months, totaling 139 people, using a sampling technique, namely proportional random sampling, of 58 people. Data analysis used chi square with the research results showing that there was a relationship between family support and smooth breastfeeding with a value of p = 0.011. It is hoped that respondents can use this as input to increase knowledge, understanding and information regarding family support which influences the smooth flow of breastfeeding.
Hubungan Pemberian Inisiasi Menyusu Dini dan Asi dengan Daya Tahan Tubuh Bayi di Puskesmas Tolo Kabupaten Jeneponto Kasmawati Kasmawati; Asmaul Husnah
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 1 (2024): Januari : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i1.262

Abstract

Colostrum, which is part of breast milk, contains immunoglobin M. Colostrum is breast milk that comes out a few days after giving birth and is clear or yellowish white. Objective: to determine the relationship between providing early initiation of breastfeeding and breast milk with the immune system of babies at the Tolo Health Center, Jeneponto Regency in 2020. The type of research used was a cross sectional study. The sample was 60 mothers who had babies aged 1-6 months who were in the working area of the Tolo Community Health Center, Jeneponto Regency. The results of the research show a relationship between giving early initiation of breastfeeding and the baby's immune system at the Tolo Community Health Center, Jeneponto Regency in 2020 with a p value = 0.024 < α 0.05. = 0.021 < α 0.05. Conclusion: there is a relationship between providing early initiation of breastfeeding and breast milk with the baby's immune system at the Tolo health center, Jeneponto Regency 2020. Suggestions: To increase knowledge and information for mothers about the importance of carrying out IMD immediately after the baby is born so that it can prevent antenatal deaths.
Faktor Yang Mempengaruhi Perkembangan Motorik Kasar Anak 3-5 Tahun di Desa Lasara Sawo Kecamatan Sawo Kabupaten Nias Dina Hura; Yanti Jernih Gea; Selvin Syukur Gea
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 1 (2024): Januari : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i2.264

Abstract

Background. Gross motor development of children from an early age can detect if there is an abnormality. This needs to be evaluated for cause as it will be affect the child's gross motor skills in the future. Research purposes. To analyze the factors that influence gross motor development in children aged 3-5 years in Lasara Sawo Village. Research design. cross sectional. Population and Sample.All parents who have toddlers aged 3-5 years totaled 35. Instrument. KPSP, questionnaires and scales. Data analysis. Chi-Square. Research result. There is a relationship parenting style, motivation and nutritional status to gross motor development (<0.05). The most dominant influential variable is the authoritarian parenting style Odd Ratio of 11,000 and a sig.(P Value) of 0.007 (<0.05). Suggestion. In providing effective education about gross motor development, it should adjust to the parenting style, motivation and nutritional status of the target.
Effects Of Psidium Guajava Crude Leaf Methanol-Extract On Lowering Blood Sugar Levels In Rat Belgis Belgis
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 1 No. 6 (2023): November : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v1i6.268

Abstract

Blood sugar levels, or blood glucose levels, are crucial for overall health and are regulated by the pancreas through insulin. Normal blood sugar levels range between 70-99 mg/dL when fasting and up to 140 mg/dL two hours after eating. Abnormal blood sugar levels can suggest a variety of health issues, including hypoglycemia (low blood sugar levels caused by excess insulin, certain drugs, or illnesses such as diabetes) and hyperglycemia (high blood sugar levels associated with diabetes). Regular blood sugar monitoring is necessary, especially for diabetics. Guava, a tropical fruit, includes a variety of phytochemicals that have been linked to pharmacological benefits such as antibacterial capabilities. This research uses an extraction process involving solid-liquid extraction or maceration, with methanol being the optimal solvent. The extract yields 9.51%. Wistar rats are used to investigate its antidiabetic efficacy. The rats are divided into three groups: positive control, negative control, and extract treatment. Diabetes is induced by subcutaneous injection of Alloxan, followed by oral administration of the methanol extract. Blood glucose levels are assessed after fasting for 6-8 hours. The extract from dried Guava leaf powder yields a concentrated extract with a 9.51% yield. In vivo assessments showed a significant reduction in blood glucose levels in rats treated with guava leaf extract, suggesting potential anti-hyperglycemic effects. The phenolic compounds in guava leaves contribute to antioxidant and anti-hyperglycemic effects. The study highlights the potential therapeutic effects of guava mint leaves and their extract components for diabetes management and antioxidant health benefits.
Analisis Kadar Logam Berat Timbal (PB) pada Makanan Kaleng Daging Giling Berbagai Merk Panji Ratih Suci; Muh. Latif 'Alim; Sulfika Oriza Nova Sativa
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 2 (2024): March : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i2.276

Abstract

Along with increasingly rapid technological developments in our country, the number of existing industries is increasing. Apart from producing useful products, this industry also produces waste. The waste produced contains a lot of heavy metals, one of which is the heavy metal lead. If the lead metal in the waste receives little treatment, this can cause pollution in the environment, even though this waste is present in small quantities, the lead condition is unstable and if it accumulates in the body, it can ultimately trigger cancer cells (carcinogenic) which can be dangerous for health. . In this research, adsorption of PB2+ ions was carried out on canned ground meat, where heavy metal contamination occurred in the ground meat. This research aims to determine the effectiveness of the absorption of heavy metals (Pb) contained in ground beef and their characteristics. The uptake of PB2+ ions in ground beef, measuring the concentration of PB2+ ions before and after receiving treatment, was carried out using an instrument, namely AAS, at a wavelength of 217nm. The research results showed that the effectiveness of ground beef in absorbing PB2+ ions in canned food was as high as brand a: 0.023; brand b: 0.009; brand c: 0.006
Pengaruh Bomb Tea Terhadap Tekanan Darah Pada Penderita Hipertensi Di Wilayah Kerja Puskesmas Baros Indah Handayani; Burhanuddin Basri; Lutiyah Lutiyah
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 2 (2024): March : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i2.278

Abstract

Background: Hypertension or high blood pressure is a non-communicable disease with abnormal blood pressure condition above the normal limit, which is higher than 140/90 mmHg. Hypertension is one of the diseases without symptoms and usually called the silent killer. There are some factors that become hypertension like genetic, lifestyle which are smoking, consuming fatty foods, and consuming alcohol. Research Objectives: to determine the effect of giving Bomb Tea (butterfly pea, lemon, and isomalt) for blood pressure in hypertension sufferers in Puskesmas Baros Area, Sukabumi City. Method: the research method used in this study was pre-experimental using one group pretest-posttest design. Respondents total in this study were 16 respondents. The result will analyze by paired t-test. Result: The statistic result by paired t-test show the p-value of systolic and diastolic blood pressure is 0,000<0,05, which means there is an effect to decrease blood pressure in hypertension sufferers. Conclusion: the conclude, there is an effect in the form of reducing blood pressure in hypertension sufferers in Puskesmas Baros Area. Suggestion: the study could become an alternative treatment by consuming Bomb Tea for decreased the blood pressure for hypertension sufferers.

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