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Articles 179 Documents
PENENTUAN UMUR STALAGMIT PROVINSI GORONTALO SEBAGAI PROXY DATA PALEOKLIMAT YUNGINGER, RAGHEL
Sainstek Vol5, No 1, 2010
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Abstract

Climate and weather area more varied and diverged, in which it impacts Indonesia significantly. Some people worry about this situation, especially they who are from agricultural, plantation, forestry, naval, and transportation areas. It becomes a consideration for the government to increase community economic activity, involving Province of Gorontalo. Moreover, Province of Gorontalo planned for Agropolitan in order to develop community economic system, so that, a preventive attempt need to find to cope climate impact. It can be conducted by providing sufficient data about past chronological climate. This data may give information about climate cycle and climate pattern that may appear in tropical area, especially in Province of Gorontalo. This research, however, is still limited to the determination of stalagmite sample age, in which it uses radiocarbon method. This method shows stalagmite sample from Province of Gorontalo has age shift of: Regency of Gorontalo 1 has 3410 130 BP age; Regency of Gorontalo 2 has 1960 130 BP; regency of Boalemo has 1830 130 BP; and regency of Pohuwato has 3190 130 BP. Stalagmit sample in the province of Gorontalo can be used to add and elongate data for paleoklimat analysis. Rapid rate of precipation for respective sample are regency of Gorontalo 1: 0.17 mm/th, sample from regency of Gorontalo 2: 0.25 mm/th, sample from regency of Boalemo mm/th, and sample from regency of Pohuwato: 0.19 mm/th. Thus, stalagmite sample from Gorontalo can add time period to determine paleoklimat chronology pattern. Key words: stalagmite, Paleoklimat, Radiocarbon method, Climate.
ANALISIS KOMPONEN KIMIA MINYAK ATSIRI PADA TANAMAN NILAM HASIL DISTILASI UAP AIR DENGAN MENGGUNAKAN KG-SM Abdjul, Najmi; Paputungan, Mardjan; Duengo, Suleman
Sainstek VOL 07, NO 01, 2013
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Abstract

Analysis of Chemical Components of Essential Oil Patchouli Plant, The Result In Steam Distillation Using The GC-MS. The aims of this study is to determine the chemical components of essential oils in patchouli plants. The method is steam distilation. Patchouli dried plant samples that have been chopped by 50 kg of steam distilled water to attract the patchouli oil components contained in the sample. The advantages of steam distillation is the hidrodifusition where moisture will get into the cell tissue of plant which resulting in rupture of the plant cell wall so that the oil contained in it will be pushed out. A mixture of water vapor and patchouli oil will flow to the condenser resulting in condensation and the resulting distilate. The distillate which containing oil and water separated by a separating funnel, until the patchouli oil. The oil which still contains water molecules that have been dried with MgSO4 previously prepared. The function addition of anhydrous MgSO4 is to bound water the which still contained in the oil. This isolation produced a yellow oil with a yield of 2,4%. The analysis of the chemical components of essensial oils is by using GC-MS. The results of using GC-MS analysis showed that there were 26 compound constituent of essential oils, with eight dominant peaks which are compounds: Patchouli alcohol (20,36%), Delta-guaiene (14,50%), Alpha-guaiene (12,89%), Pogostol (3,58%), Palustrol (1,64%), Beta-pinene (0,35%), Alpha-pinene (0,14%), and Alpha-patchoulena (7,54%). The main constituent of essential oil components are compound with patchouli alcohol levels obtained 20,36%.
STRUKTUR MIRKOANATOMI HEPAR TIKUS (RATTUS NORVEGIGUS, L) YANG DIPERLAKUKAN DENGAN MINYAK HATI IKAN COD Solang, Margaretha
Sainstek Vol 3, No 1, 2008
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Abstract

The aims of this research was to study the effects of cod liver oil on microanatomic structure of rats liver (Rattus norvegicus, L.). The present research used of Completely Randomized Design comprised of 25 Wistar males, randomly divided into five groups (A, B, C, D, and E). Group A was assigned as control, whereas B, C, D, and E were given cod liver oil with doses of 0,5, 1, 1,5, and 2 ml/b w/ day for 8 weeks, respectively. The parameters observed were microanatomic structure of rats liver (Rattus norvegicus, L.). The determination of liver for microanatomic preparation were done at the end of treatments. Qualitative data were analyzed descriptively. The research demonstrated that rats liver cells underwent plasmolyses, cloudy swelling degenerations, hydrophic degenerations, fatty degenerations and necroses (pycnoses and karyorrhexis).
FITOREMEDIASI LOGAM BERAT KADMIUM (CD) DALAM TANAH DENGAN MENGGUNAKAN BAYAM DURI (AMARANTHUS SPINOSUS L) Mohamad, Erni
Sainstek Vol 6, No 3, 2011
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Abstract

Cadmium waste is the result of industrial processes that are carcinogen material. The target organs of Cd toxicity is the kidney and liver. Cadmium waste treatment can be done by adsorption method using a plant thorn spinach (Amaranthus spinosus L). This herb has been used as an adsorbent because it contains proteins that have the amine group (-NH2), carboxyl group (-COOH), also sulfidril group (-SH). Besides, in plant tissue have a cell wall composed of cellulose, lignin-containing hydroxyl group (-OH). Polar clusters are able to bind heavy metals. The purpose of this study was to determine the ability of absorption of spinach plants with thorns as phytoremediation of metal cadmium (Cd) in tissues of roots, stems and leaves. The study was conducted with various concentration (25, 50) ppm Cd without EDTA and (25, 50) ppm Cd with EDTA. The concentration of cadmium adsorbed by plant tissue was analyzed using atomic absorption spectrophotometry (AAS) at wavelength 228.8 nm. The data were then analyzed RAL. The order of adsorption ability of the highest plant tissue concentrations of spinach with thorns on the leaves of 25 ppm Cd (7.659)> stem (6.419)> root (5.585) and at a concentration of 50 ppm Cd is the leaves (5.589)> root (5.228)> stem (4.320). At the highest concentration variation of Cd (II) adsorbed to 25, 50 ppm without EDTA and EDTA on each network is at 25 ppm of leaves (7.659
PENYELESAIAN ANALITIK DAN PEMODELAN FUNGSI BESSEL Yahya, Lailany
Sainstek Vol 5, No 3, 2010
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Abstract

Abstrak: Dalam makalah ini akan dilakukan penyelesaian analitik dan pemodelan persamaan diferensial Bessel serta menunjukkan sifat simetri pada ruang Hilbert dan ortogonalitas untuk memperoleh grafik Fungsi Bessel Jn(x) dan fungsi Neuman Nn(x). Kata kunci : Pemodelan Fungsi Bessel, Hilbert, ortogonalitas
PENGARUH PEMBERIAN GARAM SODIUM RENDAH TERHADAP PENURUNAN TEKANAN DARAH PENDERITA HIPERTENSI RAWAT JALAN DI BLUD RUMAH SAKIT UMUM PROF.DR.H. ALOE SABOE GORONTALO ., Salman; Talibo, Sofyawati; Amma, Nur Rahmi
Sainstek VOL 07, NO 02, 2013
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Abstract

Tujuan penelitian : Mengetahui pengaruh pemberian garam sodium rendah terhadap penurunan tekanan darah penderita hipertensi rawat jalan di BLUD Rumah Sakit Umum Prof. Dr. H. Aloe Saboe Gorontalo. Metode penelitian : Jenis penelitian yaitu quasi eksperimen dengan rancangan Pre and post test control group design. Subjek penelitian yaitu pasien hipertensi rawat jalan. Subjek dibagi dalam 2 kelompok, yaitu kelompok intervensi (perlakuan) dan kelompok kontrol (tanpa perlakuan). Analisa data menggunakan komputer dengan program SPSS. Analisis perbedaan mean tekanan darah sebelum dan sesudah intervensi dari masing-masing kelompok menggunakan t-test. Hasil penelitian menunjukkan karakteristik responden; umur: frekuensi terbanyak kelompok umur 55-60 tahun (49,0%); jenis kelamin terbanyak perempuan (62,5%); status/jenis pekerjaan terbanyak ibu rumah tangga/tidak bekerja (41,3%); tingkat pendidkan terbanyak tamat SLTP (45,2%). Gambaran pengaruh pemberian garam sodium rendah pada penderita hipertensi; Rata-rata penurunan tekanan darah: kelompok intervensi; sistolik 14,62 mmHg, diastolik 7,50 mmHg. Kelompok kontrol ; sistolik 5,19 mmHg dan diastolik 6,35 mmHg. Uji t pada 0,01; terdapat perbedaan signifikan rata-rata penurunan tekanan darah sistolik antara kelompok intervensi dengan kelompok kontrol (p value < 0,01) dan tidak terdapat perbedaan signifikan rata-rata penurunan tekanan darah diastolik antara kelompok intervensi dengan kelompok kontrol (p value > 0,01). Kesimpulan pemberiam garam sodium rendah berpengaruh nyata terhadap penurunan tekanan darah sistolik penderita hipertensi dan tidak berpengaruh nyata terhadap penurunan tekanan darah diastolik penderita hipertensi.
PERANCANGAN VAKSIN PROTEIN CVLP POLI INDUKSI AVIAN INFLUENZA H5N1 SUBCLADE 2.1 Amelia, Fitri; UNP, Iryani
Sainstek Vol 6, No 1, 2011
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Tingkat virulensi akibat infeksi virus influenza H5N1 sangat tinggi sehingga adanya vaksin sangat diperlukan. Telah dilakukan penelitian Research and Development (RnD) tentang perancangan vaksin protein cVLP Avian Influenza (AI) H5N1 Subclade 2.1. Penelitian ini bertujuan untuk melakukan perancangan sekuen vaksin cVLP AI H5N1 secara in silico. Penelitian dilakukan secara in silico (per-modelan/komputasi). Sekuen yang digunakan pada penelitian ini adalah sekuen protein HA dan NA H5N1 subclade 2.1. Sekuen subclade 2.1 yang didapatkan adalah 9 Sekuen protein HA dan 9 Sekuen protein NA. Sekuen yang digunakan sebagai backbone sekuen 2/2005 sebagai. Sekuen epitope B Cell protein HA adalah KSSWSDHEASS dan CNTKCQTPMGA, serta sekuen epitope B Cell protein NA adalah GDNPRPNDGTGSCG dan SDTVSWSWPDGA. Sekuen epitope T cell protein HA yang dapat digunakan adalah EKIVLLLAIVSL dan epitope T cell protein NA adalah IRPCFWVEL. Dari hasil penelitian, didapatkan 6 rancangan sekuen protein vaksin cVLP, yaitu vaksin cVLP AI H5N1 NA TBB, NA BBT, NA BTB, HA TBB, HA BBT, HA BTB. Ke-enam vaksin tersebut memiliki folding akhir yang sama dengan protein HA dan NA AI H5N1 dan bersifat immunogenic karena persen (%) identity ke-enam sekuen vaksin yang dirancang besar dari 25%. Keyword: vaksin, cVLP, Avian Influenza, H5N1
CARRAGEENAN CHARACTERISTICS FROM HARVESTING SEAWEED (KAPPAPHYCUS ALVAREZII) WITH DIFFERENT AGES Naiu, Asri Silvana; Mile, Lukman
Sainstek Vol 6, No 4, 2011
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Abstract

It has been tested against carrageenan characteristics resulting from harvesting seaweed with different ages, namely 30 days, 45 days, and 60 days. The purpose of this study was to determine the exact age of harvest in relation to the characteristics carrageenan produced from seaweed Kappaphycus alvarezii in coastal waters Desa Tolongio, Kec. Anggrek Kab. Gorontalo Utara. The research was carried out for 6 months from preparation to reporting. The method used was the explorative method, by using a Completely Randomized Design (CRD) with three replications. To determine the effect of harvest age on the characteristics carrageenan, we had tested the gel strength, viscosity, whiteness, water content, ash content and heavy metal (Hg). And to see differences between the treatment and to determine the best harvest age followed by Least Small Difference Test (LSD). All observational datas were tabulated and processed statistically using SPSS 16.0. Based on the results of research, it was known that carrageenan that was harvested of 45 days had some characteristics that approach required carrageenan for trading, namely 318.07 g/cm2 gel strength, viscosity of 101.33 cP, 10.72% ash content, and heavy metal (Hg) was not detected, whereas the water content of 23.68% and 37.2% whiteness degree was still not meet the standards of commercial carrageenan.
GANGGUAN METABOLISME TRIASILGLISEROL PADA SIROSIS HATI YANG DISERTAI DIABETES MELLITUS Ischak, Netty
Sainstek Vol 2, No 2, 2007
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Abstract

Hepatic chrrhosis is a chronic disease characterized by increasing formation of connective tissue that spread from portal spaces and also characterized by nodule formation. One of condition which becoming participating factor of hepatic chrrhosis is diabetes mellitus. Based on a data which is collected from medical record of hospital. In diabetes mellitus, it is most likely happened a disturbance of triacylglycerol metabolim. The increased accumulation of triacylglycerol in liver will be happened due to the imbalance between a formation of tryacylglycerol and a formation of VLDL. Another factor which can cause an abundant accumulation of tryacylglycerol is disturbance of the apoprotein formation, so that a VLDL formation is also disturbed. If that situation happens for a long time, the fatty liver is formed and finally hepatic chirrhosis can be happened.
FAKTOR RISIKO KEJADIAN BAYI BERAT LAHIR RENDAH (BBLR) DI RSU DR. MM DUNDA LIMBOTO KABUPATEN GORONTALO (RISK FACTORS IN THE INCIDENCE OF LOW BIRTH WEIGHT BABY AT DR. MM DUNDA HOSPITAL LIMBOTO GORONTALO REGENCY) Amalia, Lia
Sainstek Vol 6, No 3, 2011
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Abstract

Penelitian ini bertujuan untuk mengetahui besar risiko dan faktor risiko yang mana yang paling besar risikonya terhadap kejadian Bayi Berat Lahir Rendah (BBLR). Metode penelitian bersifat observasional dengan rancangan studi case control. Sampel kasus sebanyak 70 orang ibu yang melahirkan bayi dengan berat badan kurang dari 2500 gram dan sampel control sebanyak 70 orang ibu yang melahirkan bayi dengan berat badan ? 2500 gram. Data dianalisis dengan uji odds ratio dan multivariate logistic regresi pada batas kemaknaan ? = 5%. Hasil penelitian menunjukkan bahwa besar faktor risiko antara pendidikan ibu dengan kejadian BBLR, OR = 1,709, paritas dengan kejadian BBLR, OR = 3,857, pemeriksaan ANC dengan kejadian BBLR, OR = 1,605, status ekonomi dengan kejadian BBLR, OR =4,354, anemia besi dengan kejadian BBLR, OR = 4,643 dan keterpaparan asap rokok dengan kejadian BBLR, OR = 5,516. Faktor risiko yang paling besar risikonya terhadap kejadian BBLR adalah keterpaparan asap rokok dengan OR sebesar 5,385. Kata Kunci: Keterpaparan Asap Rokok, Status Ekonomi, Anemia, BBLR Abstract: This study to identifity major risk factors and risk factors which, at most, the risk of incident Low Birth Weight Babies (BBLR). Method of this research are observational with case control studies design. Sample cases as much as 70 mothers who delivered babies with body weight less than 2500 grams of sample and control as many as 70 mothers who delivered babies with body weight ? 2500 grams. The data were analyzed by using odds ratio multivariate logistic regression at ?= 5%. Results of research shows that most risk factors among mothers with education events BBLR, OR = 1,709, parity, OR = 1,678, nutritional status (Lila), OR = 3,857, with ANC, OR = 4,354, iron with anemia OR = 4,643 and exposure smoke cigarettes OR = 5,516. Risk factors the greatest risk of incidence BBLR is exposure cigarette smoke with the OR of 5,385. Keywords: Cigarette Smoke Expossed, Economic Status, Anemia, BBLR