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INDONESIA
Jurnal Indah Sains dan Klinis
Published by Yayasan Penelitian dan Inovasi Sumatera
ISSN : -     EISSN : 27471942     DOI : -
Core Subject : Health,
Dentistry Health Professions Medicine & Pharmacology Nursing
The Jurnal Indah Sains dan Klinis (JISK) is a journal about health which contains scientific and clinical issues published by the Yayasan Penelitian dan Inovasi Sumatera (YPIS) which includes studies on Pharmacy, Medicine, Nursing, Midwifery, Chemistry, Biology, Microbiology, Tissue Culture and others. other. disciplines related to health. The beginning of JISK was published at the end of December 2020, published by the Sekolah Tinggi Kesehatan Indah Medan. Since 2022, the publication of Volume 3 Number 2 has been carried out by the Yayasan Penelitian dan Inovasi Sumatera (YPIS),
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 90 Documents
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Optimasi Formula Minuman Kopi Kombinasi Ekstrak Jahe (Zingiber officinale) dan Temu Giring (Curcuma heyneana) sebagai Antioksidan Ika Julianti Tambunan; Ayuning Putri Julian; Siti Muliani Julianty; Kanne Dachi; Sumardi; Samran
Jurnal Indah Sains dan Klinis Vol 3 No 2 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i2.62

Abstract

Kopi mengandung polyphenol sebagai senyawa antioksidan. Kandungan yang terdapat pada temu giring adalah senyawa alkaloida, flavonoida, triterpenoida, saponin dan tanin sebagai antioksidan. Jahe mengandung gingerol, beta-caroten, asam mengandung gingerol, beta-caroten, asamkafeat, curc kafeat, curcumin sebagai antioksidan. Tujuan dari p umin sebagai antioksidan. Tujuan dari penelitian enelitian ini adalah untuk mengetahui apakah minuman kopi yang dikombinasikan dengan ekstrak jahe ( Zingiber officinale) dan ekstrak temu giring (Curcuma heyneana) memiliki kapasitas antioksidan dan disukai oleh sukarelawan. Penelitian ini secara eksperimental dalam menyiapkan minuman kopi yang menggabungk menggabungkan ekstrak jahe ekstrak jahe dan ekstrak temu ekstrak temu giring dan giring dan mendemonstrasi mendemonstrasikan penemuan simplisia, penemuan simplisia, produksi produksi ekstrak ekstrak jahe dan temu giring, giring, serta optimasi optimasi formula formula menggunaka menggunakan SLD ( simplex simplex lattice lattice design) dan melakukan survey survey responden responden pada setiap formula. Rendemen simplisia jahe 500 g dan temu giring 750 g giring 750 g dengan berat ekstrak jahe sebanya dengan berat ekstrak jahe sebanyak 88,8 g k 88,8 g dan berat ekstrak temu giring sebanyak 98, dan berat ekstrak temu giring sebanyak 98,2 g. Penentuan optimasi formula menggunakan SLD didasarkan pada aktivitas antioksidan formula yang optimal, yaitu rasio jahe : temu giring (1/4 : optimal, yaitu rasio jahe : temu giring (1/4 : 3/4) formula II dan hasil formula II dan hasil hedonist masing-masing formula adalah formula IV dengan rasio jahe : temu giring (3/4 : 1/4)
Efek Pemberian Ekstrak Daun Gelagah (Saccharum spontaneum L.) terhadap Diabetes Induksi Aloksan pada Tikus Putih (Rattus Norvegicus) Tiara Salsabilla Mendrofa; Asyrun Alkhairi Lubis
Jurnal Indah Sains dan Klinis Vol 5 No 1 (2024): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v5i1.05

Abstract

Saccharum spontaneum L. (Family: Poaceae) is a tall perennial grass with deep roots and rhizomes, capable of growing up to 3-4 meters in height, and is commonly found along water bodies or roadsides. This plant is widely distributed throughout the tropical regions of Asia, Africa, America, and Australia. Saccharum spontaneum L. is a tall, erect, perennial grass with feathery inflorescences, often growing in swampy areas. Its leaves and stems contain lignin, carbohydrates, proteins, and amino acids, while its roots and lower stems contain starch and polyphenolic compounds. This study aims to evaluate the effect of Saccharum spontaneum L. leaves extract on blood glucose levels in male white rats (Rattus norvegicus) induced with alloxan. The leaves extract was obtained through maceration using 96% ethanol solvent. Phytochemical screening results indicated that the leaves of Saccharum spontaneum L. contain alkaloids, flavonoids, saponins, tannins, and steroids/triterpenoids. The antidiabetic test was conducted using male Wistar rats. In this study, the Saccharum spontaneum L. leaves extract was administered in three different doses: group 4 received a dose of 100 mg/KgBW, group 5 received a dose of 200 mg/KgBW, and group 6 received a dose of 400 mg/KgBW. Additionally, there were control groups consisting of group 1 (normal), group 2 (negative control), and group 3 (positive control) which were given the drug glibenclamide 5 mg/60 kg. All doses were administered orally. Diabetes induction in the rats was performed using alloxan monohydrate at a dose of 100 mg/KgBW administered intraperitoneally. The results of the study showed that the greatest reduction in blood glucose levels occurred in group 6 with a dose of 400 mg/KgBW, which decreased blood glucose levels by 71.78% at the 180th minute. Group 5 showed a reduction of 55.80% and group 4 showed a reduction of 51.91% at the 180th minute. Group 3, which was given glibenclamide, showed a reduction in blood glucose levels of 71.14% at the 180th minute. These results indicate that the highest dose of Saccharum spontaneum L. leaves extract (400 mg/KgBW) had the most significant effect in lowering blood glucose levels in male Wistar rats induced with alloxan monohydrate
Faktor-Faktor yang Berhubungan dengan Kesehatan Reproduksi Remaja Putri di SMA Negeri 1 Ulu Moro’o Nias Barat Tahun 2021 Eva Damayanthi Gulo; Lindawati Simorangkir; Lindawati Simorangkir1; Jagentar Pane
Jurnal Indah Sains dan Klinis Vol 3 No 2 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i2.52

Abstract

Reproductive health is a significant issue that should be a worry, particularly among teenagers. Regenerative wellbeing is finished physical, mental and social wellbeing, not restricted to sickness or connected with conceptive frameworks, works and cycles as well as mental, social and social wellbeing. This study was to describe the factors related to the reproductive health of adolescent girls at SMAN 1 Ulul Moro'o in 2021. This type of research used a descriptive research design. The population of young women in SMAN 1 Ulu Moro'o West Nias with a sample of 48 people. The inspecting strategy utilized was total sampling. The estimating instrument utilized is a questionnaire. The results on the information and perspectives of young ladies about reproductive health at SMAN 1 Ulul Moro'o West Nias in 2021 were found in a very good category, namely 34 respondents (70.8%). SMAN 1 Ulu Moro'o, West Nias in 2021 in the great class, upwards of 29 respondents (60.4%). It is trusted that the after effects of this review will empower the school to give help with planning young ladies to work on their reproductive health.
Potensi Aktivitas Antioksidan Ekstrak Etanol Kering dan Segar Daun Mahkota Dewa (Phaleria macrocarpa) Herlina; Lasmaryna Sirumapea; Hilma; Yulia Azelya Salsabela
Jurnal Indah Sains dan Klinis Vol 3 No 2 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i2.68

Abstract

Compounds that function as free radical scavengers are known as antioxidants, which inhibit the oxidation process of chemical reactions and work by taking an electron to reduce the negative effects of these free radicals. The Mahkota Dewa plant (Phaleria macrocarpa), a member of the Thymelacaccae family, is known to have potential as a natural antioxidant.Various treatments prior to the extraction process of the Mahkota Dewa leaf affect the level of antioxidant activity was observed to have an effect on Both groups of leaves were extracted by maceration after part of the leaves were air-dried and partially extracted from fresh leaves. Yields were determined and phytochemical and antioxidant tests used the 1,1-diphenyl-2-picryhydrazyl method and gallic acid as a comparison. Test results showed yield values ??of 13.6% w/w (dried extract) and 9% w/w (fresh leaves). Mahkota dewa leaves contain alkaloids, flavonoids and phenolic active compounds. An antioxidant activity (IC50) value was obtained at 108.05 ppm (dried leaves). 90.97 ppm (fresh leaf) and 4.04 ppm (comparison compound). Fresh leaf sample extracts have higher antioxidant activity values than dried leaf sample extracts.
Gambaran Pengetahuan Cuci Tangan dan Memakai Masker di Masa Pandemi pada Anak Sekolah Kelas 4-5 di SD Negeri Dolok Nagodang Tahun 2021 Marni Olypia Sinaga; Lindawati Simorangkir; Amnita Ginting
Jurnal Indah Sains dan Klinis Vol 3 No 2 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i2.50

Abstract

Knowledge of hand washing and wearing masks is an action or behavior in school children that comes from experience they have or from other sources such as parents, teachers, friends and others that can reduce the spread of Covid-19 disease in order to protect themselves or control themselves from droplets. This study aims to describe the knowledge of hand washing and wearing masks during in pandemic in grade 4-5 school children at SD Negeri Dolok Nagodang Kecamatan Uluan. This research is a quantitative research and uses a total sampling. The subjects in this study were students in grade 4-5 as many 30 people. Data collection was carried out by distributing questionnaires offline. Data analysis using univariate. The results showed that of the 30 respondents who had knowledge of washing hands and wearing masks in good category, there were 22 respondents (73,3%) and knowledge of washing hands and wearing masks with sufficient category was 8 respondents (26,7%). Knowledge of washing hands and wearing masks in school children is increashing well.
Faktor Faktor yang Mempengaruhi Psikologis Remaja di Masa Pandemi Covid-19 Kelas 7-8 di SMP Negeri 1 Naman Teran Tahun 2021 Yuleen Natasya Telaumbanua; Lindawati Simorangkir; Imelda Derang
Jurnal Indah Sains dan Klinis Vol 3 No 2 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i2.51

Abstract

Psychology is part of the science of human psychology that can affect a person's life in his daily life. Factors that affect the psychology of adolescents during this pandemic are the implementation of social distancing, online learning, and the fear of contracting COVID-19. Residents between the ages of 10 and 24 are considered adolescents. The study was to find out what are the factors that affect the psychology of adolescents during the COVID-19 pandemic in class VII and class VIII at SMP Negeri 1 Naman Teran ini2021. The research method used was a descriptive research design with a total of 75 respondents. The sampling technique used was the purposive sampling technique. The results showed that the majority of students due to stress factors for the implementation of social distancing were 69 people (92.0%), the majority of students due to stress factors were online learning asimanyiasi58 people (77.3%), and the majority of students due to fear of contracting covid. -19 with mild category as many as 64 people (85.3%). This shows that the factors of implementing social distancing, online learning and the fear of contracting COVID-19 affect the psychology of the students of SMP Negeri 1 Naman Teran. It is hoped that as information and material increase their knowledge students / I further increase their knowledge about the dangers of COVID-19 transmission
Hubungan Prokrastinasi dengan Stres pada Mahasisw Tingkat Akhir yang Sedang Menyusun Skripsi di STIKes Santa Elisabeth Medan Tahun 2021 Fryska Yohana; Pomarida Simbolon; Maria Pujiastuti
Jurnal Indah Sains dan Klinis Vol 3 No 2 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i2.60

Abstract

Students can never stay away from pressure. Stress is an unavoidable condition throughout everyday life and everyone has different feelings of anxiety. During the time of completing the thesis, students are faced with various obstacles, requests, and pressures. This is what causes students to prefer to procrastinate and it can be seen that student stress is influenced by the procrastination of the student. This research method uses an in-depth exploration configuration using a cross-sectional methodology. The example in this review was 62 respondents with the testing system, specifically basic arbitrary examining. The p-value of 0.001 (p < 0.05) indicates it that there is a relationship between indecision and student stress when composing a student proposal for the Nursing Study Program of STIKes Santa Elisabeth Medan 2021. They expected that students could motivate themselves to work on their thesis and manage their time so they don't experience problems, stress and no procrastination occurs.
Formulasi dan Uji Antioksidan Sediaan Krim Ekstrak Etanol Buah Asam Cikala (Etlingera elatior (Jack) R. M. Sm) sebagai Pelembab Kulit Zebua, Nilsya Febrika; Sudewi; Siti Arum Widiyanti; Muflihah Fujiko; Nurul Karimah; Supran Hidayat; Rahma Yulia
Jurnal Indah Sains dan Klinis Vol 3 No 2 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i2.63

Abstract

Cikala acid fruit is fruit of kecombrang plant (Etlingera elatior) which phenolic compounds including flavonoids and has strong antioxidants activity. Antioxidants are nutrients in the form of vitamins and minerals that function to prevent and repair damaged body tissues. Antioxidant compounds are generally used in cosmetic products. The purpose of this study to determine the antioxidant activity of the ethanolic extract of the cikala fruit was formulated into a moisturizing cream. This research is experimental, covering extract manufacture, phytochemical screening, manufacture and testing of cream preparations as well as testing of antioxidant activity in moisturizing cream. The cream formulation formula was made with a concentration ratio of 1.5%, 2%, 2.5% and blank. Chemical compounds from the ethanolic extract of cikala fruit are alkaloids, saponins, flavonoids and triterpenoids; has a homogeneous cream dosage form with a pH range of 5.7-6.1 after short storage and 12 weeks of storage; and has antioxidant activity with inhibitor concentration value of 19.92 g/mL at concentration 2.5%.
Gambaran Komunikasi Interpersonal Mahasiswa dengan Dosen Prodi Ners di STIKes Santa Elisabeth Medan Tahun 2021 Nestariang Laia; Lindawati F. Tampubolon; Ance M. Siallagan
Jurnal Indah Sains dan Klinis Vol 3 No 2 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i2.54

Abstract

Interpersonal communication is a process and effort of individuals or groups in influencing by conveying information or messages intended to other individuals both verbally and nonverbally so that feedback and interactions occur between the two parties as a process of transferring knowledge from lecturers to students. In this investigation, we'll find out the description of interpersonal communication between students and lecturers at the Nursing Study Program of STIKes Santa Elisabeth Medan. This type of research is descriptive research design, the sampling in this study used a total sampling technique, their respondent were 91 people. The results of the research showed that the interpersonal communication of third-level Nurses students with the majority of lecturers was in the pretty good category (94.5%). with the existence of interpersonal communication students with lecturers can be maintained or improved for the better.
Hubungan Self Efficacy dengan Kemampuan Berpikir Positif pada Remaja di SMP Karya Bhakti Kecamatan Tarabintang Kabupaten Humbang Hasundutan Tahun 2021 Elisabeth Christina Tumanggor; Lindawati Simorangkir; Amnita Ginting
Jurnal Indah Sains dan Klinis Vol 3 No 2 (2022): Jurnal Indah Sains dan Klinis
Publisher : Yayasan Penelitian dan Inovasi Sumatera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/jisk.v3i2.61

Abstract

Self efficacy is someone who has high confidence where individuals are able to direct behavior to be active and more diligent with all academic activities. Positive ability to reason is a disposition or conduct that is possessed to have the option to settle on decisions by utilizing a solid and clear psyche that starts or emerges from positive energy and furthermore sees everything with regards to its decency. This study expects to decide if there is a connection between self-viability and positive ability to reason. The exploration strategy utilized is connection with cross sectional methodology, the quantity of respondents is 53 individuals. This retrieval techniqueiis done by using questionnaires that are distributed directly. Sampling using simple random sampling with aitotal of 53 respondents. Their results showed that most of the respondents with High Self Efficacy were 43 people (81.1%) with the ability to think positively in the high category as many as 25 people (47.2%). Thelr results of the Fisher's Exact Test correlation test with a p-value of 0.488 (p <0.05) means that there is no significant relationship between self-efficacy and the ability to think positively in adolescents at Karya Bhakti Junior High School, Tarabintang District, Humbang Hasundutan Regency. The conclusion is that the self-efficacy of Karya Bhakti Junior High School students is very high, while students who have very low positive thinking skills are expected to be better able to change attitudes or behavior to improve their ability to think positively and apply self-efficacy in each individual.

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