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Henni Vanda
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Fakultas Kedokteran Hewan USK Faculty of Veterinary Medicine Universitas Syiah Kuala Banda Aceh Jl. Tgk. Hasan Krueng Kalee No. 4 Kampus FKH USK, Darussalam, Banda Aceh 23111
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Jurnal Medika Veterinaria
Published by Universitas Syiah Kuala
ISSN : 08531943     EISSN : 25031600     DOI : 10.21157/j.med.vet..v18i1
Core Subject : Health, Science, Agriculture,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Veterinary
Jurnal Medika Veterinaria is published biannually in February and August. The scope of this journal includes Veterinary Medicine, Animal Science, Science, and Medicine. The journal accepts original research papers, case study, and review article. All submissions are evaluated by peer reviewers who are experts in the relevant fields. The content of accepted papers is the responsibility of the authors and does not necessarily reflect the opinions of the editors. The aims of this journal: 1. To promote the advancement of veterinary medicine through the dissemination of high-quality, peer-reviewed research and clinical studies. 2. To facilitate the sharing of knowledge and innovations in veterinary science among researchers, practitioners, and educators. 3. To encourage interdisciplinary collaboration by publishing research that intersects with related fields such as animal science, biomedical research, and public health.
Arjuna Subject : Kedokteran Hewan - Kedokteran Hewan (Lain-Lain)
Articles 333 Documents
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In Vitro Analysis of Antibacterial Activity of Black Seed Oil Against Salmonella Typhi Zulfayanto, Indri; Vanda, Henni; Hambal, Muhammad; Sari, Wahyu Eka; Muttaqien, Muttaqien
Jurnal Medika Veterinaria Vol 19, No 2 (2025): J.Med.Vet
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v19i2.48983

Abstract

Salmonella sp. is one of the bacteria that causes diarrhea in animals and humans, especially in naive animals whose immune systems have not yet been formed. In relation to the emergence of antibiotic resistance against Salmonella typhi, it is necessary to develop an innovation regarding alternative medicines that use herbal medicines as antibacterials, one of which is black seed oil which contains active substances such as thymoquinone. Nigella sativa, commonly known as black seed, has long been used as herbal medicine with many benefits. This study aimed to determine the antibacterial activity of black seed oil against S. typhi bacteria in vitro. This study used S. typhi ATCC 14028, which had been previously re-identified using Gram staining. The black seed oil for the antibacterial test was prepared with three concentrations, 45%, 70%, and 100%, with dimethyl sulfoxide (DMSO) as a negative control and ciprofloxacin as a positive control. Black seed oil's antibacterial test was carried out using the Kirby Bauer method. The data was analysed descriptively. The results showed that black seed oil was not effective in inhibiting the growth of S. typhi, where the inhibition zone formed was less than 5 mm. This is because the antigenic structure of S. typhi has Vi antigens or capsular antigens which are made of polysaccharide polymers found outside the cell to protect the bacteria from outside influences. Therefore, the active ingredients in the black seed oil was unable to reach the site of action on the bacteria so they failed to inhibit or kill the S. typhi bacteria. It can be concluded that the black seed oil used in this study was not effective in inhibiting the growth of S. typhi ATCC 14028
Coccidiosis In Broiler Chicken Aged 27 Days From A Farm In Tunjuk, Marga, Tabanan, Bali: A Case Study Amelia, Ni Kadek Shita; Suratma, Nyoman Adi; Berata, I Ketut; Besung, I Nengah Kerta; Mahardika, I Gusti Ngurah Kade
Jurnal Medika Veterinaria Vol 19, No 2 (2025): J.Med.Vet
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v19i2.48001

Abstract

Coccidiosis, also commonly referred to as bloody diarrhea, is caused by Eimeria spp. and primarily affects the digestive tract. The most pathogenic Eimeria species in chickens are Eimeria tenella and Eimeria necatrix. The subject of this case study was a 27-day-old female broiler chicken from a commercial farm located in Tunjuk Village, Marga Subdistrict, Tabanan Regency, Bali. The chicken had been reported to suffer from bloody diarrhea for five days, accompanied by clinical signs of weakness, anorexia, pale comb, ruffled feathers, and a tendency to huddle in the corner of the pen. This case study aimed to describe the anatomical pathology, histopathology, and laboratory findings to obtain a definitive diagnosis of the disease affecting this chicken. The results of the anatomical pathology examination showed hemorrhage in the cecum. Histopathological examination of the cecum revealed the presence of schizonts, hemorrhage, and inflammatory cell infiltration. Qualitative fecal examination confirmed the presence of Eimeria spp. oocysts, while quantitative fecal examination using the McMaster technique revealed 895,600 oocysts per gram of feces, indicating a severe infection. Based on clinical observations, epidemiological data, gross pathological changes, histopathological findings, and fecal examinations using native, sedimentation, flotation, and McMaster methods, it was concluded that the chicken was affected by coccidiosis.
Antihyperuricemic Effect of the Combination of Eleutherine bulbosa and Syzygium polyanthum Extracts on Uric Acid Reduction in Hyperuricemic Mice Indriani, Amanda; Hujjatusnaini, Noor; Nurindahsari, Lilin Ika
Jurnal Medika Veterinaria Vol 19, No 2 (2025): J.Med.Vet
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v19i2.48281

Abstract

Hyperuricemia is a metabolic disorder characterized by elevated serum uric acid levels, which may lead to gout and other related complications. Long-term pharmacological treatments often cause adverse effects, making natural products a promising alternative therapy. This study aimed to evaluate the antihyperuricemic activity of a combined extract of Eleutherine bulbosa (Dayak onion) and Syzygium polyanthum (bay leaf) in hyperuricemic mice (Mus musculus). The experiment employed a post-test only control group design using 28 male Balb/c mice induced with a high-purine diet to establish hyperuricemia. Treatments included single and combined extracts of E. bulbosa and S. polyanthum at doses of 100, 200, and 300 mg/kg body weight with a ratio of 1:2, alongside a positive control (allopurinol). Phytochemical analysis revealed the presence of flavonoids, tannins, and saponins, which act as xanthine oxidase inhibitors and synergistic antioxidants. Statistical analysis using one-way ANOVA indicated a significant effect of the extract combination on reducing serum uric acid levels (p = 0.016). Further Duncans post-hoc test identified the 200 mg/kg dose (1:2 ratio) as the most effective, exhibiting a response comparable to allopurinol. These results suggest that the combination of E. bulbosa and S. polyanthum extracts possesses significant antihyperuricemic potential and may serve as a candidate for the development of stable phytopharmaceutical formulations for hyperuricemia therapy

Page 34 of 34 | Total Record : 333

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