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Jurnal Pharma Bhakta
Published by Institut Ilmu Kesehatan Bhakti Wiyata Kediri
ISSN : -     EISSN : 27971163     DOI : 10.56710
Core Subject : Health,
Health Professions Medicine & Pharmacology
Jurnal ini mempublikasikan hasil penelitian pada fokus dan bidang : 1. Biologi Farmasi 2. Farmasi Komunitas 3. Teknologi Farmasi 4. Kimia Farmasi 5. Farmakologi dan Farmasi Klinik
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 83 Documents
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Optimization of the Combination of Canna Tubers (Canna indica L.) – Avicel PH 101 as a Diluent for Direct Compression Ibuprofen Tablets Erfan Tri Prasongko; Andri Dodik Kurniawan
JURNAL PHARMA BHAKTA Vol 6 No 1 (2026): Mei (2026)
Publisher : FACULTY OF PHARMACY, INSTITUT ILMU KESEHATAN BHAKTI WIYATA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56710/jpb.v6i1.171

Abstract

Background: Canna tuber (Canna Indica L.) is a plant that contains large amounts of carbohydrates, so it can be used as a starch producer. Canna starch is starch extracted from canna tubers can be used to diluent. Objective: to determine the effect of the combination of green canna tuber starch with Avicel Ph 101 as a filler for ibuprofen tablets on the physical form of tablets and to determine the optimum formulation of the combination of canna tuber starch. with avicel PH 101. Method: This study is an experimental research using a descriptive method. The samples in this study were formulations combining canna tuber starch and Avicel PH 101 as fillers in directly compressed ibuprofen tablets, using the Simplex Lattice Design (SLD) method. Results: The physical quality test of the tablets from the 5 formulas met the requirements for the uniformity test of tablet weight, tablet size uniformity test formulas, tablet hardness test, friability test, and the dissolution test of the 5 formulas meets the requirements within 60 minutes of dissolving not less than 85% of the amount indicated on the label. Conclusions: The formulation of Ibuprofen tablets with Avicel PH 101 as a filler combined with canna tuber starch can affect the physical quality. The optimum formula for ibuprofen tablets combined with canna tuber starch and Avicel PH 101 is the proportion of canna tuber starch as much as 50,000 mg and Avicel PH 101 as much as 50,000 mg, with a desirabilty value of 1,000.
PHARMACOGNOSTIC CHARACTERIZATION, PHYTOCHEMICAL SCREENING, AND MICROBIOLOGICAL QUALITY EVALUATION OF BEAN LEAF (Phaseolus vulgaris L.) SIMPLICIA: PHARMACOGNOSTIC CHARACTERIZATION, PHYTOCHEMICAL SCREENING, AND MICROBIOLOGICAL QUALITY EVALUATION OF BEAN LEAF (Phaseolus vulgaris L.) SIMPLICIA Nurul Istiqomah; Dhevi Indah Puspita Sari; Faizatul Fitria; Muh. Shofi; Siti Munawaroh
JURNAL PHARMA BHAKTA Vol 6 No 1 (2026): Mei (2026)
Publisher : FACULTY OF PHARMACY, INSTITUT ILMU KESEHATAN BHAKTI WIYATA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56710/jpb.v6i1.172

Abstract

ABSTRACT Background: Common bean leaves (Phaseolus vulgaris L.) are horticultural plant materials with potential use as traditional herbal medicine due to their diverse secondary metabolites that exhibit various health-promoting properties. Pharmacognostic characterization and quality evaluation are essential to ensure the quality and safety of herbal raw materials. Objective: This study aimed to determine the microscopic characteristics, moisture content, loss on drying, phytochemical profile, and microbiological quality of common bean leaves. Methods: This study was conducted using a descriptive approach. Common bean leaf simplicia was extracted by maceration using 70% ethanol. Microscopic observations were performed on fresh leaves and powdered simplicia. Quality evaluation included the determination of moisture content, loss on drying, phytochemical screening, and microbial contamination through Total Plate Count and Yeast and Mold Count analyses. Results: The extraction process yielded an extract recovery of 11.78%. Microscopic analysis revealed the presence of epidermal tissues, stomata, trichomes, and sclerenchyma. The moisture content and loss on drying were 3.0% and 2.1%, respectively. Phytochemical screening indicated the presence of alkaloids, flavonoids, saponins, tannins, triterpenoids, and steroids. The Total Plate Count and Yeast and Mold Count were 1.6 × 10⁵ CFU/g and 3.1 × 10³ CFU/g, respectively. Conclusion: Common bean leaves possess distinctive pharmacognostic characteristics, contain various potentially bioactive secondary metabolites, and meet microbiological quality requirements for use as herbal raw materials. Keywords: Phaseolus vulgaris L., pharmacognostic characteristics, phytochemical screening, microbiological quality
STUDY OF PHYTOCHEMICAL COMPOUND CONTENT AND ANALGESIC ACTIVITY OF ETHANOL EXTRAK OF CELERY LEAF (Apium graveolens L.) WRITHING TEST METHOD: STUDY OF PHYTOCHEMICAL COMPOUND CONTENT AND ANALGESIC ACTIVITY OF ETHANOL EXTRAK OF CELERY LEAF (Apium graveolens L.) WRITHING TEST METHOD Rosa Juwita Hesturini; Fathul Hidayatul Hasanah; Dwi Wahyuni; Briandini Dwi Astuti; Anis Anggrayni
JURNAL PHARMA BHAKTA Vol 6 No 1 (2026): Mei (2026)
Publisher : FACULTY OF PHARMACY, INSTITUT ILMU KESEHATAN BHAKTI WIYATA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56710/jpb.v6i1.173

Abstract

Background: The celery plant (Apium graveolens L.) belongs to the Apiaceae family and is one of the vegetable commodities that is widely used for flavoring and decorating dishes with various health benefits. Objective: This study aims to determine the content of phytochemical compounds and analgesic activity of celery leaves. Through a systematic review article. Method: The research method with systematic literature review was carried out by searching for articles or journals related to phytochemical compound content and analgesic activities of celery. which had been published in journals. Literature search was conducted in April-May 2021 through Google Scholar, then journals were selected based on exclusion and inclusion criteria. Conclusions: The inclusion criteria, namely journals published last 5 years, the journal discusses the content of phytochemical compounds and analgesic activity of ethanol extract of celery leaves using the writhing test method. And as for the exclusion criteria, the data in the journal is incomplete and the journal does not discuss the celery plant. Based on the results of a systematic literature review of 5 published journals indicate that celery plant contains phytochemicals flavonoid compounds, tannins, saponins flavor-glucoside (apiin), apigenin and have analgesic activity.

Page 9 of 9 | Total Record : 83

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