cover
Contact Name
Rizal Irfandi
Contact Email
rizalirfandi043@gmail.com
Phone
+6285215254648
Journal Mail Official
rizalirfandi043@gmail.com
Editorial Address
Jl. Bumi 18 Blok A 15 No. 1 Bumi Permata Hijau, Makassar, Sulawesi Selatan, Indonesia
Location
Kota makassar,
Sulawesi selatan
INDONESIA
Hayyan Journal
ISSN : -     EISSN : 30466679     DOI : https://doi.org/10.51574/hayyan.v1i1.1130
Focus and Scope This journal publishes articles related to chemistry. The scope of this journal includes: Inorganic Chemistry Organic Chemistry Physical Chemistries Chemical Instruments Analytical Chemistries Materials Chemicals Industrial chemistry Biochemistry Applied Science Applied Chemistry
Articles 79 Documents
Relationship Between Knowledge and Attitude of Breastfeeding Mothers in Providing Exclusive Breastfeeding at Pattingaloang Health Center Asmirah, Rika; Rahmawati, Rahmawati
Hayyan Journal Vol. 2 No. 1 (2025): February
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v2i1.2795

Abstract

The first thousand days of life are a golden period that greatly determines the optimal growth and development of children. Exclusive breastfeeding plays an important role in meeting the nutritional needs of infants and reducing morbidity and mortality rates in children. However, the coverage of exclusive breastfeeding has not yet reached the expected target. Various factors, including the level of knowledge and attitude of mothers, are thought to influence the success of exclusive breastfeeding. This study aims to analyze the factors that influence exclusive breastfeeding in infants over 6 months of age in the Pattingaloang Health Center work area, South Sulawesi. This study used a correlation analytic design with a cross-sectional approach. The sample in this study were 33 mothers who had infants aged 6–24 months and were selected using the total sampling technique. Data were obtained through questionnaires and analyzed using the Chi-square test with the help of SPSS. The results of the analysis showed that there was a significant relationship between the level of maternal knowledge and exclusive breastfeeding (p-value = 0.028). Mothers with good knowledge are more likely to provide exclusive breastfeeding than mothers with poor knowledge. Meanwhile, no significant relationship was found between the mother's attitude towards breastfeeding and exclusive breastfeeding (p-value = 0.532). In addition, age, education level, and occupation also contribute to the formation of maternal knowledge about exclusive breastfeeding. The level of maternal knowledge significantly influences the success of exclusive breastfeeding, while maternal attitudes do not show a significant relationship. Therefore, efforts are needed to increase education and counseling regarding the importance of exclusive breastfeeding, especially for mothers with low education levels or limited access to health information
The Effect of Efflurange Message on Reducing Labor Pain Intensity at Ujungloe Health Center Alinengsih, Wahyuni; Nabila, Nabila
Hayyan Journal Vol. 2 No. 1 (2025): February
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v2i1.2796

Abstract

Effleurage massage is one of the massages that can reduce the intensity of labor pain. Effleurage massage is done on the back area where massage in that area can relax the muscles, provide a peaceful rest and increase the comfort of the mother during labor. Gentle massage on the back area can play a role in reducing the intensity of labor pain. The purpose of this study was to determine the effect of effleurage massage on reducing the intensity of labor pain in mothers giving birth at the Ujungloe Health Center. This study is a type of quasi-experimental study with the design used is a pretest posttest one group design. This design has a pretest, before being given treatment with a total sample of 18 respondents using total sampling usingWilcoxon testsign rank test.The results of this study were obtained(p value = 0.000 <0.05) then it was found that there was a significant effect of giving effleurage massage in reducing labor pain, it was found that the frequency of back pain in mothers giving birth normally before effleurage massage, the most respondents felt moderate pain as many as 12 respondents (67%) and after effleurage massage, the most respondents felt mild pain as many as 15 respondents (83%). The conclusion of this study is that effleurage massage has an effect on reducing labor pain at the Ujungloe Health Center. This study is expected to provide benefits for the development of obstetrics, one waywhich can be done to reduce labor pain with non-pharmacological actions, furthermore, researchers are expected to provide training to midwives in health centers so that they can be more skilled in carrying out message efflurange to mothers in labor to reduce labor pain.
Utilization of Natural Products as a Source of Novel Antibiotics: A Literature Review Afni, Nur
Hayyan Journal Vol. 2 No. 2 (2025): June
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v2i2.3128

Abstract

Antibiotic resistance is a growing global health concern that threatens the effectiveness of current treatments against bacterial infections. Natural products have long served as essential reservoirs for the discovery of bioactive compounds, including antibiotics, owing to their structural diversity and ecological functions. This literature review highlights recent advances (2016–2025) in the identification and development of novel antibacterial compounds derived from natural sources such as medicinal plants, soil actinomycetes, marine organisms, endophytes, and extremophiles. It also discusses the molecular mechanisms underlying their antibacterial actions and addresses modern approaches in natural product-based drug discovery, including genome mining, metabolomics, artificial intelligence, and synthetic biology. Despite various challenges, such as the rediscovery of known molecules and low yields, innovative strategies continue to drive the development of promising antibiotic candidates. This review emphasizes the untapped potential of natural resources and advanced technologies in tackling the global antimicrobial resistance crisis.
Review Article: Phytochemical Screening and Potential Biological Activities of Lahuna Plants ( Chromolaena odorata L.) Jumrah, Elfira
Hayyan Journal Vol. 2 No. 1 (2025): February
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v2i1.3129

Abstract

Chromolaena odorata L., locally known as the Lahuna plant, is a tropical plant with great potential in traditional medicine. This study uses a qualitative approach method that critically examines the results of previous studies on the phytochemical content and potential biological activity of the Chromolaena odorata L. plant. This review article discusses the results of phytochemical screening and the potential biological activity of various secondary metabolite compounds contained in the plant, such as flavonoids, alkaloids, saponins, tannins, and terpenoids. Various studies have shown that C. odorata has broad pharmacological activities, including antibacterial, anti-inflammatory, antioxidant, and wound-healing agents. With its abundant bioactive content, this plant has great potential to be developed as a source of natural medicine. However, its clinical use still requires further scientific validation through toxicity tests, pharmacodynamics, and clinical trials. This article aims to provide a scientific basis for the potential of C. odorata in the field of phytopharmaceuticals and encourage further research for its development.
Review of Transition Metal Dithiocarbamate Complexes: Novel Fluorescent Materials for Biosensor Applications Irfandi, Rizal
Hayyan Journal Vol. 2 No. 2 (2025): June
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v2i2.3149

Abstract

Transition metal complexes with dithiocarbamate ligands have attracted significant attention in recent decades due to their unique electronic and optical properties. This article presents a comprehensive review of transition metal-dithiocarbamate complexes as fluorescent materials and their potential in biosensor development. Focus is given on their chemical structure, fluorescence mechanism, as well as their application in detecting important biomolecules. With the increasing need for sensitive, selective, and low-cost biosensors, these materials offer promising prospects in various biomedical and environmental applications.
Abundance of Endophytic Bacteria in Sauropus androgynus and Evaluation of Chitinolytic Activity Sri Ayu Anggita
Hayyan Journal Vol. 2 No. 2 (2025): June
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v2i2.3175

Abstract

This study aimed to isolate and evaluate the biological safety and potential of endophytic bacteria from Sauropus androgynus (katuk) and their Chitinolytic activity for use as biological agents. A total of 14 endophytic bacterial isolates were obtained from different plant parts: 5 from the roots (T1, T2, T3, T4, P14), 5 from the stems (T7, T8, T9, T10, T11), and 4 from the leaves (T5, P6, KB12, T13). The safety of these isolates was assessed through hypersensitivity (HR) and hemolysis (HL) tests. In the HR test, none of the isolates induced necrotic symptoms in tobacco leaves, indicating they are not pathogenic to plants. In the HL test, two bacterial which were T4 from roots and T5 from leaves, isolates were found to produce clear zones on blood agar, indicating α-hemolysin production. However, the other isolates did not form hemolysis zones, suggesting they are safe for mammals. Antibacterial activity against the plant pathogen Ralstonia solanacearum was evaluated using spot inoculation methods. The results showed that none of the isolates were able to inhibit the growth of R. solanacearum. Further testing revealed that one bacterial isolate which was T8 obtained from the stem produced chitinase, as evidenced by the formation of a clear zone around the bacterial colony on chitin-containing media.
Caulerpin: Biosynthetic Significance and Cytotoxic Activity Against Artemia salina Leach Dini, Iwan
Hayyan Journal Vol. 2 No. 2 (2025): June
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v2i2.3261

Abstract

Caulerpin (1) is one of the bisindole alkaloid compounds isolated from the many macroalga species of the Halimeda and Caulerpa genera. The biosynthetic significance of 1 is suggested by the biotransformation of indole-3-acetic acid to indole-3-carboxaldehyde via tryptophan from the shikimate pathway. This compound has many biological activities reported and this time, the 1 were evaluated for their cytotoxicity in the brine shrimp assay against A. salina Leach. in vitro and showed moderate activity with IC50 value 81.28 µg/mL.
Valorization of Trash Fish Through Drying Innovations: Nutrient Stability of Protein, Calcium, and Phosphorus Salnus, Subakir; Zulfian Armah
Hayyan Journal Vol. 2 No. 2 (2025): June
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v2i2.3274

Abstract

Trash fish, often regarded as low-value bycatch, actually holds significant potential as a source of protein and essential minerals such as calcium and phosphorus. This study aims to evaluate the effect of different drying methods—oven drying at varying temperatures (40°C, 60°C, 80°C, and 100°C) and sun drying on the protein, calcium, and phosphorus content of trash fish. Laboratory analyses were conducted using the Kjeldahl method for protein determination and atomic absorption spectrophotometry (AAS) for calcium and phosphorus content. The results revealed that increasing oven drying temperatures significantly reduced protein levels, while sun drying maintained a protein content close to the optimal range. In contrast, calcium and phosphorus levels showed no significant differences across drying methods. Therefore, low-temperature oven drying or sun drying is recommended to preserve the nutritional quality of trash fish effectively.
Voltammetric Sensing in Portable and Point-of-Care Devices A Review of Recent Trends and Applications Eka Kartika, Andi
Hayyan Journal Vol. 2 No. 2 (2025): June
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The growing demand for rapid, low-cost, and decentralized analytical technologies has driven the development of portable voltammetric sensors and point-of-care (POC) devices. This review examines recent advancements in miniaturized voltammetric systems, with a particular emphasis on innovations in screen-printed electrodes (SPEs), microfluidic integration, plug-and-play configurations, and smartphone-enabled electrochemical platforms. These technological developments exhibit substantial potential for real-time, on-site analytical applications across various fields, including medical diagnostics, environmental monitoring, food safety, and wearable health technologies. Several studies are highlighted to illustrate the practical implementation of voltammetric sensing, including glucose and uric acid detection, cancer biomarker analysis, heavy metal monitoring, pesticide screening, and nitrite and formaldehyde detection in food. The review also discusses major challenges such as signal noise, sensor stability, energy constraints, and the need for user-friendly interfaces. Finally, it outlines future research directions, focusing on the incorporation of artificial intelligence (AI), the Internet of Things (IoT), and low-power electronics to enable fully autonomous and smart diagnostic systems. These developments position voltammetric sensing as a vital tool in the future of accessible, real-time, and personalized analytical technologies.
Assessing Toxic Levels in Facial Creams from Burung-Burung Traditional Market, Gowa Salnus, Subakir
Hayyan Journal Vol. 2 No. 1 (2025): February
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v2i1.3373

Abstract

Facial cream is a skin care product that is widely used to improve appearance and overcome various skin problems. However, some unregistered products, especially those sold in traditional markets, can contain hazardous materials such as mercury. This study aims to identify the presence and levels of mercury in unregistered facial whitening creams sold in the Burung-Burung Traditional Market, Pattallassang District, Gowa Regency. Samples were analyzed using the Atomic Absorption Spectrophotometry (AAS) method. The results showed that five of the eight samples contained mercury exceeding the threshold set by BPOM RI, which is 1 mg/kg. This finding emphasizes the need for stricter regulation and supervision of cosmetic products to protect public health.