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Rizal Irfandi
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Jl. Bumi 18 Blok A 15 No. 1 Bumi Permata Hijau, Makassar, Sulawesi Selatan, Indonesia
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INDONESIA
Hayyan Journal
Published by Education and Talent Development Center Indonesia
ISSN : -     EISSN : 30466679     DOI : https://doi.org/10.51574/hayyan.v1i1.1130
Core Subject : Health, Science, Engineering,
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Engineering Medicine & Pharmacology
Focus and Scope This journal publishes articles related to chemistry. The scope of this journal includes: Inorganic Chemistry Organic Chemistry Physical Chemistries Chemical Instruments Analytical Chemistries Materials Chemicals Industrial chemistry Biochemistry Applied Science Applied Chemistry
Arjuna Subject : Kimia(semua kategori) - Kimia (Lain-Lain)
Articles 79 Documents
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Literature Study: Chemical Content and Benefits of Bidara Leaves (Ziziphus Muritiana) as an Indonesian Herbal hajeriani
Hayyan Journal Vol. 1 No. 2 (2024): June
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v1i2.1603

Abstract

Plants with various varieties can be found in various regions in Indonesia. Many varieties of medicinal plants in Indonesia have been used as raw materials for making medicines and several of these plant types have been clinically evaluated for their phytochemical composition, efficacy and safety of use. Bidara leaves, scientifically known as Zizhipus mauritiana L., are often used in Traditional Chinese Medicine to cure a number of diseases, such as urinary problems, digestive disorders, fever, liver complaints, weakness, anemia, obesity, diabetes, bronchitis, skin infections, loss of appetite. eating, pharyngitis, diarrhea, cancer, and insomnia. The reference literature obtained from the search results is then studied and examined to determine research findings, then described using the data or samples collected as is. Based on research and literature studies, bidara leaves have various significant health benefits, especially because of their rich chemical compound content. The flavonoid, tannin, terpenoid, steroid, alkaloid, triterpenoid and saponin compounds in bidara leaves have been proven to have anti-microbial, anti-depressant, anti-inflammatory, anti-oxidant and anti-cancer activity. Furthermore, bidara leaves can also protect body cells such as the kidneys and brain from oxidative stress, which is one of the main risk factors for cancer. Therefore, bidara leaves can be a safe and natural alternative treatment for various diseases and health conditions.
Review Article: Phytochemical And Pharmacological Study Of Teapot Grass (Cyperus Rotundus L) As A Medicinal Plant Sudirman, Suharni
Hayyan Journal Vol. 1 No. 2 (2024): June
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v1i2.1625

Abstract

This research is a literature study. The purpose of this study is to determine the chemical content contained in teki grass and its medicinal potential, increase the use of teki grass as a traditional medicine by conducting more systematic and scientific research, and find alternative traditional medicines that are effective and safe for various diseases. This research was prepared using the literature study method. The data collection process was carried out with a literature study on relevant articles and related to the phytochemical study of teki grass plants and the development of its parts that can be utilized. The journal review process involved analyzing relevant articles, with a focus on empirical research conducted within the last 10 years. The search for articles and some data was conducted using Google Scholar and Chat Gpt academic data. Previous phytochemical studies on teki grass tubers revealed the presence of alkaloids, flavonoids, tannins, starch, glycosides and furochromones, and sesquiterpenoids. In the phytochemical test, it was found that teki grass contained alkaloids, saponins, flavonoids, tannins, essential oils and sesquiterpenoids. These compounds are found in parts of the teki grass plant such as leaves, and tubers. Teapot grass plants also have pharmacological activities as wound healing, anti-inflammatory, antimicromial, antibacterial, antioxidant and analgesic activities.
Review Article: Chemical Compound Content in Balakacida (Chromolaena odorata) Plants as Traditional Medicine Sudirman, Sudarmianti
Hayyan Journal Vol. 1 No. 2 (2024): June
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v1i2.1626

Abstract

Pemanfaatan tanaman-tanaman yang ad disekitar sebagai alternative pengobatan. Balakacida (Chromolaena odorata) tumbuh subur dan disebut gulma namun dapat dijadikan obat alternative. Tujuan penelitian ini untuk mereview artikel dan merangkum tentang kandung dan pemanfaatan tanaman balakacida. Teknik penelitian ini, menggunakan metode tinjauan literatur dan berkonsentrasi pada banyak penelitian mengenai kemungkinan senyawa kimia yang terkandung dalam tanaman balakacida sebagai pengobatan tradisional. Data primer karya ilmiah dikumpulkan dari jurnal nasional dan internasional melalui pencarian di mesin pencari elektronik seperti Google Scholar, ScienceDirect, dan Tailor & Francis dinilai, dievaluasi, dan ditafsirkan oleh penulis. Kandungan senyawa yang terdapat pada tanaman balakacida yaitu, fenolik, minyak atsiri, saponin alkaloid, flavonoid, flavanon, tanin, dan terpenoid. Kandungan dari tanaman balakacida menjadi bersifat antibakteri, antiinflamasi, dan anelgesik. Pemanfaatan tanaman balakacida digunakan sebagai obat luka, gatal, maag, dan sebagai aromaterapi.
General Description of Glucose and pH in the Urine of Diabetic Mellitus Patients by using Urine Analyzer Permata, Indra; Rasyid, Nur Qadri; Nurhidayat; Wahyuni, Sri; Muawanah
Hayyan Journal Vol. 1 No. 2 (2024): June
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v1i2.1884

Abstract

Diabetes Mellitus is a chronic disease that occurs due to the failure of the pancreas to produce enough insulin or the body cannot effectively use the insulin produced. One of the complications of diabetes is diabetic ketoacidosis. KAD is an acute complication of Diabetes Mellitus characterized by increased glucose levels. Diabetic Mellitus has higher levels of calcium stones, and uric acid, therefore the pH of the urine of people with Diabetic Mellitus tends to be more acidic. The purpose of the study was to find out the picture of the results of glucose and pH tests in patients with Diabetes Mellitus. The type of research used in this study is laboratory observation. The sampling technique in this study is random sampling. The number of samples in this study was 10 samples, with the Urine Analyzer examination method. The results of the study showed that out of 10 samples studied, 4 samples were found to be glucose-positive, with a pH range of 5 – 7 and 6 samples were not found to be glucose positive with a pH range of 5 - 6.
Exploration of Traditional and Modern Values of Bidara (Ziziphus mauritiana) Leaf in the Community of Tancung Village, Tanah Sitolo Sub-District, Wajo District nurhaeda, zahra
Hayyan Journal Vol. 2 No. 3 (2025): October
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v2i3.3448

Abstract

This study aims to explore the utilization and meaning of bidara leaves (Ziziphus mauritiana) in the lives of people from various generational and professional backgrounds. Data were obtained through interviews with six resource persons, namely traditional healers, housewives, fathers, grandmothers, millennial aunts, and local residents. The results of the interviews showed that bidara leaves have strong traditional values, such as being used in the ritual of bathing corpses, treating wounds, and treating supernatural disorders. On the other hand, modern uses are starting to develop, such as being used in beauty products, skincare, and as a symbol of spiritual healing on social media. The findings show that bidara leaves have not only survived as part of tradition, but have also been successfully adapted into modern lifestyles, reflecting the continuity and transformation of values in society.
Characterization of Active Carbon Pineapple Skin (Ananas comosus) as Absorbent of Heavy Metal Copper (Cu) with NaOH and NH4OH Activators Abd Haris, Miftahul Jannah; Musdalifah1; Herdie Idriawien Gusti; Syahdam Karneng
Hayyan Journal Vol. 2 No. 3 (2025): October
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v2i3.3524

Abstract

This research aims to evaluate the potential of pineapple peel as a raw material for making activated carbon, as well as comparing the effectiveness of NaOH and NH4OH activators in the activation process. Activated carbon is produced through a carbonization and chemical activation process, then its quality is tested based on the Indonesian National Standard (SNI) 06-3730-1995. The research results show that activated carbon from pineapple peel meets SNI standards in terms of ash content and water content, with each not exceeding the maximum limits of 10% and 15%. The yield of activated carbon activated with NH4OH (87.5%) was higher than NaOH (79.4%). In addition, the water content of activated carbon with NH4OH (1.07%) is lower than NaOH (1.42%). Although the iodine absorption capacity of activated carbon from pineapple peel is still below the minimum SNI standard (750 mg/g), NH4OH shows better results in adsorption of the heavy metal Cu (0.0041 mg/g) than NaOH (0.0015 mg/g ). The FTIR spectrum shows the presence of diverse functional groups, indicating complex chemical interactions. Based on the results of this research, pineapple peel has good potential as a raw material for activated carbon, with NH4OH as a more effective activator in improving the quality and adsorption ability of activated carbon.
The content of Compounds and Bioactivity of the Eucalyptus sp species Abd Haris, Miftahul Jannah; Andi Nur Fitriani Abubakar; Karneng, Syahdam; Indriani, Iin; Idriawien Gusti, Herdie; Surahmat; Febrianti, Triana
Hayyan Journal Vol. 2 No. 3 (2025): October
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v2i3.3580

Abstract

Eucalyptus sp. is one of the plant genera from the Myrtaceae family which is widely known for its diverse secondary metabolite content and high biological activity. This study aims to systematically examine the diversity of active compounds and potential bioactivity of various Eucalyptus species, especially in the leaves, bark, seeds, and essential oils. Various compounds such as 1,8-cineole, citronellal, flavonoids, and phenolic compounds have been shown to contribute to pharmacological activities such as antioxidants, antimicrobials, anti-inflammatory, immunomodulators, anticancer, as well as natural insecticides and repellents. The results of the review indicate that these activities have great relevance in the development of biopharmaceutical products, cosmetics, and other health applications. The diversity of compounds and broad pharmacological effects place Eucalyptus as a very potential source of natural materials to be developed sustainably.
Review of the Agronomic and Biochemical Potential of Eucalyptus Plants ( Melaleuca cajuputi ) as Essential Oil Producers Siti Fatimah; Ilda Yangti; Andi Nurfitri Abubakar; Karneng, Syahdam; Indriani, Iin; Surahmat; Febrianti, Triana
Hayyan Journal Vol. 2 No. 3 (2025): October
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v2i3.3615

Abstract

Studi ini mengeksplorasi potensi agronomi dan biokimia Melaleuca cajuputi (kayu putih) melalui tinjauan pustaka komprehensif penelitian Indonesia yang diterbitkan antara tahun 2019 dan 2024. Tujuannya adalah untuk mengevaluasi efektivitas berbagai strategi budidaya khususnya sistem agroforestri, pemupukan organik, dan perbaikan genetik dalam meningkatkan produktivitas dan kualitas minyak atsiri kayu putih. Hasil menunjukkan bahwa pola agroforestri menggunakan serai wangi ( Cymbopogon nardus ) yang ditumpangsarikan dengan varietas Sitrona 2 Agribun menghasilkan produksi minyak tertinggi (2,84%) dan kandungan 1,8-sineol (hingga 52,98%). Pemupukan organik menggunakan kompos tandan kosong kelapa sawit meningkatkan kesuburan tanah dan pertumbuhan tanaman, sementara inokulasi mikoriza arbuskular secara signifikan meningkatkan kelangsungan hidup bibit dan perkembangan daun. Lebih lanjut, varietas yang dipilih secara genetik menghasilkan 1,2–1,3% hasil minyak dengan kadar sineol mencapai 68–75%. Temuan ini menunjukkan manfaat sinergis dari praktik agronomi terpadu dan pemuliaan tanaman dalam menghasilkan minyak kayu putih berkualitas tinggi untuk aplikasi industri dan lingkungan yang berkelanjutan.
Kinetics of Phenol Degradation Using TiO₂/Zeolite Composite Kartika, Andi Eka; Side, Sumiati; Eka Pratiwi, Diana; Afni, Nur
Hayyan Journal Vol. 2 No. 3 (2025): October
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v2i3.4138

Abstract

Phenol is a hazardous organic pollutant commonly found in industrial wastewater and is difficult to degrade through conventional treatment methods, thus requiring more effective and sustainable approaches. Photocatalytic degradation using TiO₂ has been widely explored; however, its performance is limited by rapid electron–hole recombination and low surface area. Combining TiO₂ with zeolite enhances adsorption capability and increases the availability of active sites, offering a promising strategy to improve photocatalytic efficiency. This study aims to analyze the kinetic behavior of phenol degradation using a TiO₂/zeolite composite and to determine the optimum irradiation time based on a pseudo-first-order kinetic model. Irradiation times of 15, 30, 45, 60, and 75 minutes were applied, and phenol concentrations were measured using UV–Vis spectrophotometry at 270,20 nm. The results show rapid degradation during the first phase (15-30 minutes), with removal efficiency increasing from 83,014% to 87,315%. After 30 minutes, the degradation rate becomes nearly constant, indicating the attainment of photocatalytic dynamic equilibrium. The -ln(Ct/C0) plot reveals two distinct reaction phases: an initial high-rate phase followed by a plateau phase. Therefore, 30 minutes is identified as the most efficient irradiation time, representing the point at which maximum degradation is achieved before the reaction rate significantly decreases. These findings provide meaningful insight into the photocatalytic kinetics of TiO₂/zeolite composites and support their potential application in phenolic wastewater treatment.
A Narrative Review of Natural Bioactive Agents for Wound Healing: Mechanistic Insights on Anti-Inflammatory, Angiogenic, Antimicrobial, and Tissue Regeneration Pathways Afni, Nur
Hayyan Journal Vol. 2 No. 3 (2025): October
Publisher : Education and Talent Development Center of Indonesia (ETDC Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51574/hayyan.v2i3.4211

Abstract

Wound healing is a complex biological process involving the coordinated progression of hemostasis, inflammation, proliferation, and extracellular matrix (ECM) remodeling. Chronic and infected wounds often fail to progress through these stages due to persistent inflammation, oxidative stress, and microbial biofilm formation. In recent years, natural bioactive compounds have gained attention as potential therapeutic agents due to their multi-target biological functions and biocompatibility. This review synthesizes evidence from original in vitro, in vivo, and clinical studies to evaluate the mechanisms of natural compounds, including curcumin, Centella asiatica derivatives, honey-based molecules, flavonoids, and chitosan biomaterials in modulating the wound-healing process. The findings demonstrate that natural compounds can enhance platelet-mediated hemostasis, suppress inflammatory cytokines through NF-κB inhibition and Nrf2 activation, stimulate angiogenesis via VEGF and TGF-β signaling, promote fibroblast proliferation and collagen synthesis, and exert antimicrobial and antibiofilm effects against drug-resistant pathogens. Formulation strategies such as hydrogels and nanoparticle delivery systems were also shown to improve compound stability, tissue penetration, and therapeutic outcomes. These results indicate that natural bioactive wound-healing agents provide a promising avenue for managing both acute and chronic wounds, particularly in contexts where antibiotic resistance or delayed healing presents clinical challenges.

Page 7 of 8 | Total Record : 79

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