cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Rolan Rusli
Contact Email
admin@jurnalfamul.com
Phone
+6282154639509
Journal Mail Official
admin@jurnalfamul.com
Editorial Address
Gedung Administrasi Fakultas Farmasi Universitas Mulawarman, Jalan Penajam, Kampus UNMUL Gn. Kelua, Samarinda, 75119. Indonesia.
Location
Kota samarinda,
Kalimantan timur
INDONESIA
Jurnal Sains dan Kesehatan
Published by Universitas Mulawarman
ISSN : 23030267     EISSN : 24076082     DOI : 10.25026/jsk
Core Subject : Health, Science, Agriculture,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology
Jurnal Sains dan Kesehatan menerima naskah karya asli (Artikel Penelitian, Artikel Review, dan Studi Kasus), baik eksperimental maupun teoretis, dalam bidang-bidang berikut: Sains dan Kesehatan (Kedokteran, Farmasi, Kesehatan Masyarakat, Keperawatan, Kebidanan, Gizi, dan lain-lain). Tujuan penerbitan Jurnal Sains dan Kesehatan adalah untuk menyediakan informasi ilmiah tentang perkembangan ilmu dan teknologi di bidang Ilmu Pengetahuan dan Kesehatan.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 750 Documents
 33   34   35   36   37 
Formulasi dan Uji Sifat Fisik Facial Wash Ekstrak Methanol Daun Salam (Eugenia polyntha) sebagai Antioksidan dengan Metode DPPH (1,1-difenil-2-pikrihidrazil): Formulation and Physical Properties Test of Facial Wash Methanol Extract of Salam Leaf (Eugenia polyntha) as Antioxidant Using DPPH Method (1,1-Diphenyl-2-Picrylhydrazil) Try Kurniawati; Titi Pudji Rahayu; Naelaz Zukhruf Wakhidatul Kiromah
Jurnal Sains dan Kesehatan Vol. 4 No. 3 (2022): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v4i3.983

Abstract

Daun salam (Eugina polyntha) merupakan tanaman yang mengandung flavonoid yang memiliki aktivitas sebagai antioksidan sehingga dapat dibuat sediaan facial wash. Facial wash merupakan salah satu pembersih wajah yang digunakan untuk membersihkan sel kulit mati, kotoran, minyak dan kosmetik. Tujuan penelitian ini yaitu untuk membuat sediaan facial wash dengan variasi karbopol 940 yang memenuhi uji fisik sediaan dan mempunyai aktivitas antioksidan dengan metode DPPH. Metode penelitian yaitu penelitian ini bersifat eksperimental dengan merancang formulasi sediaan facial wash daun salam dengan variasi karbopol 940 dan evaluasi sediaan fisiknya meliputi uji organoleptis, uji pH, uji viskositas, uji stabilitas, uji iritaai dan uji hedonik. Uji aktivitas antioksidan dilakukan dengan menggunakan metode DPPH (1,1-Difenil-2-Pikrilhidrazil). Hasil evaluasi sifat fisik facial wash meliputi organoleptik formula 1, 2, 3, 4, 5, 6 memiliki bentuk sediaan gel, bau khas daun salam, dan warna hijau kehitaman. Sediaan homogen dan memiliki nilai pH pada rentang 4,5-6,5, tinggi busa pada formulasi ke 3 memenuhi standar, uji viskositas memenuhi standar pada formulasi ke 2 dan 3, , uji iritasi tidak adanya iritasi pada formulasi ke 3 dan untuk formulasi 1, 2, 4, 5, 6 memiliki sedikit iritasi, uji hedonik dilakukan dengan kriteria bentuk, warna dan bau yang banyak disukai pada formulasi ke 2. Pengujian Pengujian ststistik dengan hasil uji pH, uji tinggi busa dan uji viskositas dilakukan dengan uji One Way ANOVA dengan hasil untuk nilai p < 0,05. Hasil nilai  pada vitamin C sebesar 8,88 ppm sedangkan untuk sediaan facial wash daun salam sebesar 10,53 ppm. Pada penggunaan basis gel karbopol 940 mepengaruhi sifat fisik sediaan dengan p <0,05, dan nilai  sebesar 8,88 ppm untuk vitamin C sebagai kontrol positif dan sediaan facial wash  ekstrak metanol daun salm dengan nilai  sebesar 10,53 ppm.
Tes Takayama sebagai Sarana Identifikasi Sampel Darah Terpapar Media Dekomposisi Tanah: Takayama Test as a Means of Identification of Blood Samples Exposed to Soil Decomposition Media Oktavia Sari; Eriko Prawestiningtyas
Jurnal Sains dan Kesehatan Vol. 4 No. 3 (2022): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v4i3.996

Abstract

In criminal cases, blood spots are one of the markers of a crime. Spots left on an object, no matter how small, can be used as evidence, whether it comes from humans or not. Criminals often try to eliminate traces of their actions by hiding or disposing of bloodstained items in the hope of complicating the investigation process. This study refers to the use of the Takayama Test in determining the origin of blood spots. This test is one of the method to test whether the spots found are blood or not, and confirm th origin of the blood. Based on the number of cases in which the perpetrators disposed of evidence, this study aims to determine the extent to which the Takayama Test is used to identify blood spots on cloth with the influence of soil decomposition media. The study used a True Experimental design with randomization and a control group. Data analysis using descriptive analysis. The results obtained from observations for 30 days, the Takayama test showed positive results and could identify the presence of blood spots on the soil decomposition media. A positive result is indicated by the presence of hemochromogen crystals that form on blood spots that have been exposed to the soil. The formation of brownish black crystals was found in the spots exposed to the soil medium.
Analisis Efektivitas Biaya dan Minimal Biaya Pasien Diabetes Melitus Tipe 2 di RSUD Abdul Wahab Sjahranie Samarinda Tahun 2019: Cost Effectiveness Analysis and Minimum Cost for Type 2 Diabetic Mellitus at Abdul Wahab Sjahranie Hospital Samarinda 2019 Imanuel Saputra Sembiring; Dewi Rahmawati; Adam M. Ramadhan
Jurnal Sains dan Kesehatan Vol. 4 No. 3 (2022): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v4i3.999

Abstract

Diabetes mellitus (DM) is a metabolic disorder and characterized by hyperglycemia and disorders of the metabolism of carbohydrates, fats, proteins. The purpose of this study was to determine the characteristics of Diabetes mellitus patients, the pattern of treatment carried out, and appropriate anti diabetic in terms of cost and effectiveness aspects at Abdul Wahab Sjahranie Regional Hospital Samarinda. The study was conducted retrospectively on medical record records. The results of 115 patients showed that most Diabetes mellitus sufferers were suffered by man with an age range of 56-65 years. The most common use of anti diabetic in Diabetes mellitus patients is bolus insulin and combination of bolus and basal insulin. Anti diabetic with minimal cost or the most minimal cost are the cost of using bolus insulin at a cost of Rp 8.865.248,-. The antidiabetics combination of basal and bolus is more effective reducing blood sugar levels while 174,86 mg/dL with an average cost effectiveness ratio (ACER) value of Rp 57.199,22,-.
Kajian Konsentrasi Ekstrak Daun Sirih Merah (Piper crocatum) sebagai Bahan Aktif Antiseptik dalam Sediaan Sabun Padat : Study of Concentration of Red Betel Leaf Extract (Piper crocatum) as Antiseptic Active Ingredient in Solid Soap Lisna Meylina; Arsyik Ibrahim; Laode Rijai
Jurnal Sains dan Kesehatan Vol. 3 No. 6 (2021): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v3i6.1001

Abstract

Sirih merah (Piper crocatum) merupakan salah satu tanaman yang diketahui secara empiris berkhasiat sebagai antiseptik. Melihat potensi tersebut, memungkinkan sirih merah untuk dikembangkan lebih jauh dalam produk sediaan farmasi. Tujuan penelitian ini adalah untuk mendapatkan konsentrasi ekstrak daun sirih merah sebagai bahan aktif dalam sediaan sabun padat yang efektif sebagai antiseptik serta mengetahui kestabilan fisik dari sediaan tersebut. Pengujian efektivitas antiseptik dilakukan dengan menggunakan metode difusi agar dan pengujian stabilitas fisik (busa dan pH) yang diukur dan diamati selama 4 minggu. Hasil efektivitas antiseptik sediaan diperoleh hasil yang baik terhadap ketiga mikroba uji (Escherichia coli, Staphylococcus aureus dan Candida albicans) dimana diperoleh konsentrasi ekstrak daun sirih merah yang paling efektif sebagai antiseptik adalah 1% (F2) dibandingkan dengan kontrol negatif. Hasil dari pengujian stabilitas fisik selama 4 minggu diperoleh kestabilan busa yang baik serta pH sediaan yang stabil.
Status Gizi Mahasiswa Universitas Pertahanan Republik Indonesia Program S1 Angkatan 1: Nutritional Status of Indonesia Defense University’s Student S1 Program Batch 1 Dwi Monik Purnamasari; Yolanda Safitri; Elies Fitriani; Rachma Hidana; Adristi Anargya Athallah; Roy Envito Utama; Cahya Wahyudi Januarta; Astikahilda Maria Pangemanan; Handrian Rahman Purawijaya; Grace Joselini Corlesa; Alfa Januar Krista
Jurnal Sains dan Kesehatan Vol. 3 No. 6 (2021): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v3i6.1007

Abstract

Indonesia is currently having a double burden of malnutrition (undernutrition and obesity). Nutritional status affects human health quality. In 2020, Indonesia Defense University launched a new undergraduate program to fulfill the needs of human resources in military and ministry of defense. Early detection of nutritional status is needed to determine so that malnutrition can be followed up. This research was conducted by using a cross sectional method with the 288 subjects. Measurement of nutritional status was done through examination of Body Mass Index (BMI) and body fat percentage by using a Bioelectrical impedance analysis (BIA). Result showed that based on BMI, 8% of all subjects were obese, 64.6% were in normal nutritional status, 20.1% were overweight, and 7.3% were undernourished. If classified by gender, 6.7% of male students were obese, 24.7% were overweight, 7.3% were underweight, and 61.2% were in normal nutritional status, while for female cadets, 10% were obese, 70% were normal, 12.7% were overweight, and 7.3% were underweight. Based on the percentage of body fat by using the BIA, it was found that 83.3% of subjects were normal and 16.7% of all subjects were obese. If classified by gender, 2.2% of male students and 40% of female students were obese. It can be concluded that the prevalence of obesity and underweight among all cadets according to BMI were relatively low, but the proportion of overweight and percent body fat among cadets were quite high.
Kajian Pola Peresepan Antibiotik pada Pasien Dewasa di Puskesmas Rawat Inap Nipah Panjang Kabupaten Tanjung Jabung Timur Tahun 2019: Study of Antibiotic Prescribing Patterns in Adult Patients in Nipah Panjang Inpatient Health Center, Tanjung Jabung Timur Regency in 2019 Rasmala Dewi; Indri Meirista; Raodatul Husna
Jurnal Sains dan Kesehatan Vol. 4 No. 3 (2022): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v4i3.1019

Abstract

Salah satu permasalahan kesehatan yang penting untuk diperhatikan alat penyakit infeksi. Penyakit infeksi khususnya di negara berkembang harus segera diatasi dengan pemberian obat kepada penderita, seperti obat yang mengandung antibiotik, antivirus, antijamur, dan anti protozoaKandungan yang paling banyak digunakan masyarakat adalah antibiotik. Antibiotik berhasil dimanfaatkan sebagai obat adalah karena ketepatan dalam peresepan antibiotik. Antibiotik yang tidak sesuai aturan resep akan membuat terjadinya ketidakrasionalan di dalam tubuh penderita. Penelitian ini dilaksanakan di Puskesmas rawat inap Nipah Panjang Kabupaten Tanjung Jabung Timur pada tahun 2019. Metode penelitian yang digunakan adalah deskriptif retrospektif. Berdasarkan hasil penelitian, sebanyak 360 pasien sudah menggunakan antibiotik yang terdiri atas kandungan amoxicillin 68,61%, cefadroxil 9,17%, ciprofloxacin 16,11%, chloramfenikol 4,17%, eritromicyn 1,39%, dan metrominazole 0,56%. Pasien yang mendapatkan antibiotik kombinasi sebanyak 2 resep. Semua peresepan memenuhi ketepatan dosis dan frekuensi dan lama pemberian kecuali pada penggunaan antibiotik eritromicyn dan kloramfenikol. Sebanyak 328 resep tidak memenuhi ketepatan durasi penggunaan antibiotik
Aktivitas Antioksidan dan Tabir Surya Ekstrak Etanol Tanaman Crassocephalum crepidioides (Benth.): Antioxidant and Sunscreen Activity of Ethanol Extract of Crassocephalum crepidioides (Benth.) Rolan Rusli; Ismah Nuri; Mahdyya Afiana Ramadani; Vita Olivia Siregar; Mukti Priastomo; Muhammad Faisal
Jurnal Sains dan Kesehatan Vol. 4 No. 3 (2022): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v4i3.1026

Abstract

Crassocephalum crepidioides (sintrong) plant has secondary metabolites such as flavonoids, saponins, steroids, and tannins which are thought to have antioxidant and sunscreen activities. Antioxidant activity of the ethanol extract of the leaves and flowers of Sintrong was measured using Uv-Vis spectrophotometry obtained IC50 values of 23.558 ppm (flowers) and 0.62 ppm (leaves), and categories as very strong antioxidants. Based on %Te and %Tp values, ethanol extract of sintrong leaves was categories as sunblock, while ethanol extract of flowers of sintrong was categories as Fast Tanning (for %Te) and for %Tp was categories as suntan standard (for 200-300 ppm) and Extra Protection (for 400-600 ppm). The SPF of the ethanol extract of the leaves and flowers of sintrong is categories as minimal protection.
Uji Efektivitas Antidiabetik Kombinasi Ekstrak Daun Senggani (Melastomapolyanthum .Bl) dan Glibenklamid dalam Menurunkan Kadar Glukosa Darah pada Mencit (Mus Musculus): Antidiabetic Effectiveness Test of A Combination of Senggani (Melastoma Polyanthum .Bl) and Glibenclamide Leaf Extract in Reducing Blood Glucose Levels in Mice (Mus Musculus) Sry Widyastuti; Samsidar Usman; Dina Rahayu
Jurnal Sains dan Kesehatan Vol. 4 No. 3 (2022): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v4i3.1028

Abstract

This study aims to determine the antidiabetic effectiveness of the combination of Senggani leaf extract (Malestoma polyanthum Bl.) And Glibenclamide against alloxan-induced mice. This study used 15 male mice divided into 5 groups and each group consisted of 3 male mice, group I was given Na.CMC 1% w / v, groups III, IV, V were each given a combination of senggani leaf extract 90 mg / kg, 180 mg / kg, 360 mg / kg and 5 mg of glibeclamide as the treatment group, and for group II were given glibenclamide suspension 5 mg for comparison. Alloxan 150 mg / KgBW was used as an inducer of diabetes. Measurement of blood glucose levels was carried out three times, namely initial glucose measurement, post-induction glucose measurement and post-treatment glucose measurement. The results showed that giving senggani leaf extract with a concentration of 90 mg / kg BW, 180 mg / kg BW, 360 mg / kg BW had an antidiabetic effect in male mice. Senggani leaf extract 360 mg / kg BW showed the most effective antidiabetic effect, but still more smaller than the 5 mg glibenclamide suspension.
Aktivitas Antibakteri Ekstrak Bawang Hitam Variasi Waktu Aging Terhadap Pencegahan Dysbiosis Kulit Penyebab Jerawat: Antibacterial Activity of Black Garlic Extract Variations in Aging Time on Prevention of Skin Dysbiosis Causes Acne Luthfia Hastiani Muharram; Fauzia Ningrum Syaputri; Wulan Pertiwi; Rizki Fika Saputri
Jurnal Sains dan Kesehatan Vol. 4 No. 2 (2022): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v4i2.1035

Abstract

Skin diseases, including acne, can be caused by a microbial imbalance (dysbiosis). The specific bacteria involved in acne dysbiosis are Cutibacterium (Propionibacterium) acnes and Staphylococcus epidermidis. Black garlic has better potential to be alternative antibiotic and chemical to curing ance and maintaining skin health, because it has antimicrobial potential and can inhibit the decrease in collagen deposition on the skin. These potentials can be alternative of antibiotics and chemicals to treat acne and maintain healthy skin. This study aimed to determine the antibacterial activity of black garlic extract against bacteria that cause acne dysbiosis. Garlic was aging with 3 variations of time (7, 14, and 21 days) then macerated with 70% alcohol and tested for antimicrobial activity to Cutibacterium acnes and Staphylococcus epidermidis with clindamycin as positive control. Black garlic extract provided inhibitory activity against Staphylococcus epidermidis and Cutibacterium acnes. The best recommendation time for aging garlic to prevent skin dysbiosis causes acne is 7 to 14 days.
Uji Efektivitas Antiseptik Obat Kumur Ekstrak Daun Sirih Hijau (Piper betle L.) Terhadap Bakteri Isolat Mulut: Effectiveness Test of Mouthwash Antiseptic Green Betel Leaf Extract (Piper betle L.) Against Oral Isolate Bacteria Nurhidayati Harun; Evi Febrianti S
Jurnal Sains dan Kesehatan Vol. 4 No. 3 (2022): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v4i3.1036

Abstract

Karies gigi disebabkan oleh bakteri Streptococcus mutans, penanganan menggunakan obat kumur dinilai efektif karena dapat membersihkan mulut sampai ke sela-sela gigi. Tujuan dari penelitian ini untuk mengetahui pengaruh obat kumur ekstrak daun sirih hijau (Piper betle L.) sebagai antiseptik terhadap isolat mulut. Uji aktivitas antiseptik  menggunakan metode koefisien fenol dengan konsentrasi ekstrak  10%, 20%, dan klorheksidin 0,2% sebagai kontrol positif. Isolat mulut dibudidayakan selama 24 jam pada media agar darah menggunakan metode streak plate. Penentuan nilai koefisien fenol dilakukan dengan melihat kekeruhan pada media nutrient broth. Hasil penelitian obat kumur ekstrak etanol daun sirih hijau meenunjukkan aktivitas antiseptik terhadap bakteri isolat mulut. Terdapat perbedaan rerata nilai koefisien fenol Obat kumur ekstrak daun sirih hijau konsentrasi 10% (0,887 ± 0,273), 20% (1,760 ± 0,730), dan klorheksidin 0,2% (1,360 ± 0,446). Hasil analisis statistik menunjukkan tidak terdapat perbedaan efektivitas antiseptik obat berdasarkan uji koefisien fenol. Berdasarkan penelitian dapat disimpulkan bahwa formula obat kumur memiliki efektivitas membunuh isolat mulut.

Page 35 of 75 | Total Record : 750

 33   34   35   36   37 

Filter by Year

2015 2025


Reset
Filter By Issues
All Issue Vol. 7 No. 6 (2025): J. Sains Kes. Vol. 7 No. 5 (2025): J. Sains Kes. Vol. 7 No. 4 (2025): J. Sains Kes. Vol. 7 No. 3 (2025): J. Sains Kes. Vol. 7 No. 2 (2025): J. Sains Kes. Vol. 7 No. 1 (2025): J. Sains Kes. Vol. 6 No. 6 (2024): J. Sains Kes. Vol. 6 No. 5 (2024): J. Sains Kes. Vol. 6 No. 4 (2024): J. Sains Kes. Vol. 6 No. 3 (2024): J. Sains Kes. Vol. 6 No. 2 (2024): J. Sains Kes. Vol. 6 No. 1 (2024): J. Sains Kes. Vol. 5 No. 6 (2023): J. Sains Kes. Vol. 5 No. 5 (2023): J. Sains Kes. Vol. 5 No. 4 (2023): J. Sains Kes. Vol. 5 No. 3 (2023): J. Sains Kes. Vol. 5 No. 2 (2023): J. Sains Kes. Vol. 5 No. SE-1 (2023): Spesial Edition J. Sains Kes. Vol. 5 No. 1 (2023): J. Sains Kes. Vol. 4 No. 6 (2022): J. Sains Kes. Vol. 4 No. 5 (2022): J. Sains Kes. Vol. 4 No. 4 (2022): J. Sains Kes. Vol. 4 No. 3 (2022): J. Sains Kes. Vol. 4 No. 2 (2022): J. Sains Kes. Vol. 4 No. SE-1 (2022): Spesial Edition J. Sains Kes. Vol. 4 No. 1 (2022): J. Sains Kes. Vol. 3 No. 6 (2021): J. Sains Kes. Vol. 3 No. 5 (2021): J. Sains Kes. Vol. 3 No. 4 (2021): J. Sains Kes. Vol. 3 No. 3 (2021): J. Sains Kes. Vol. 3 No. 2 (2021): J. Sains Kes. Vol. 3 No. 1 (2021): J. Sains Kes. Vol. 2 No. 4 (2020): J. Sains Kes. Vol. 2 No. 3 (2020): J. Sains Kes. Vol. 2 No. 2 (2019): J. Sains Kes. Vol. 2 No. 1 (2019): J. Sains Kes. Vol. 1 No. 10 (2018): J. Sains Kes. Vol. 1 No. 9 (2018): J. Sains Kes. Vol. 1 No. 8 (2017): J. Sains Kes. Vol. 1 No. 7 (2017): J. Sains Kes. Vol. 1 No. 6 (2016): J. Sains Kes. Vol. 1 No. 5 (2016): J. Sains Kes. Vol. 1 No. 4 (2015): J. Sains Kes. Vol. 1 No. 3 (2015): J. Sains Kes. Vol. 1 No. 2 (2015): J. Sains Kes. Vol. 1 No. 1 (2015): J. Sains Kes. More Issue