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INDONESIA
Jurnal Sains dan Kesehatan
Published by Universitas Mulawarman
ISSN : 23030267     EISSN : 24076082     DOI : 10.25026/jsk
Core Subject : Health, Science, Agriculture,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology
Jurnal Sains dan Kesehatan menerima naskah karya asli (Artikel Penelitian, Artikel Review, dan Studi Kasus), baik eksperimental maupun teoretis, dalam bidang-bidang berikut: Sains dan Kesehatan (Kedokteran, Farmasi, Kesehatan Masyarakat, Keperawatan, Kebidanan, Gizi, dan lain-lain). Tujuan penerbitan Jurnal Sains dan Kesehatan adalah untuk menyediakan informasi ilmiah tentang perkembangan ilmu dan teknologi di bidang Ilmu Pengetahuan dan Kesehatan.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 764 Documents
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Karakteristik Fisik Morfologi, pH, dan Waktu Alir Serbuk Serat Ampas Kelapa sebagai Bahan Pengisi Sediaan Farmasi: Physical Characteristics Morphology, pH, and Flow Time of Coconut Pulp Fiber Powder as a Filling Material for Pharmaceutical Preparations Amatullah Syarifah; Tuti Sri Suhesti; Rehana
Jurnal Sains dan Kesehatan Vol. 4 No. 3 (2022): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v4i3.1133

Abstract

Utilization of coconut pulp fiber is still low so that it can be used in the pharmaceutical industry. This study aims to determine the physical characteristics of morphology, pH, and flow time of coconut pulp fiber powder as a filler in pharmaceutical preparations. The procedure of this research was started by making coconut pulp fiber powder, morphological characteristic test, pH test, and flow time test. The results of this study are: (1) Morphological characteristics test, coconut pulp fiber powder has a slightly yellowish white color, tasteless, odorless, and roughness of 426-600 m which means it is in accordance with pharmaceutical grade; (2) the pH of the powder is 6.43 which means it is close to neutral; and (3) the flow time test showed a result of 4.73 grams/second, which means the powder can flow well. In conclusion, coconut pulp powder can be used as a filler in pharmaceutical preparations.
Diseksi Spontan Arteri Koroner: Diagnosis dan Manajemen: Coronary Artery Spontaneous Dissection: Diagnosis and Management Sidhi Laksono; Yogi Subandra
Jurnal Sains dan Kesehatan Vol. 5 No. 1 (2023): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v5i1.1137

Abstract

Spontaneous coronary artery dissection (SCAD) is one of the rare causes of ACS cases but is increasing in incidence in young women with low cardiovascular risk assessment. In addition, SCAD has risk factors for pregnancy and fibromuscular dysplasia. Establishing the diagnosis of SCAD by coronary angiography is a challenge because the characteristics of SCAD are similar to other causes of ACS and often missed. It is hoped that SCAD can be a research concern to support diagnosis and management to produce better outcomes. Keywords: coronary artery spontaneous dissection, diagnosis, management, acute coronary syndrome Abstrak Diseksi spontan arteri koroner (Spontaneous Coronary Artery Dissection: SCAD) salah satu penyebab kasus SKA yang jarang tetapi meningkat insidensi pada wanita muda dengan penilaian risiko kardivaskular rendah. Selain itu SCAD memiliki faktor risiko terhadap kehamilan, dan penyakit fibromuscular dysplasia. Penegakan diagnosis SCAD dengan angiografi koroner menjadi tantangan dikarenakan karakteristik SCAD yang mirip dengan penyebab ACS lainnya dan sering kali terlewat. Diharapkan SCAD dapat menjadi perhatian penelitiaan untuk mendukung penegakan diagnosis dan manajemen guna menghasilkan keluaran lebih baik. Kata Kunci: diseksi spontan arteri koroner, diagnosis, manajemen, sindroma korone akut
Front Cover, Editorial Information, Table of Content, Author Guideline, Back Cover Journal Editor
Jurnal Sains dan Kesehatan Vol. 4 No. 1 (2022): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v4i1.1144

Abstract

Pola Peresepan Antipsikotik Pasien Skizofrenia Di RSJ Mutiara Sukma Provinsi NTB Tahun 2020: Antipsychotic prescribing patterns for Schizophrenia Patients at RSJ Mutiara Sukma NTB Province In 2020 Candra Eka Puspitasari; Ni Made Amelia Ratnata Dewi; Siti Rahmatul Aini; Raisya Hasina; Iman Surya Pratama
Jurnal Sains dan Kesehatan Vol. 4 No. 3 (2022): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v4i3.1151

Abstract

Prevalensi skizofrenia di NTB menempati urutan ketiga nasional yaitu mencapai 9,6%. Terapi primer skizofrenia adalah antipsikotik untuk mencegah timbulnya kekambuhan gejala. Penelitian ini bertujuan untuk mengetahui pola peresepan obat antipsikotik pada pasien skizofrenia. Penelitian ini merupakan penelitian non eksperimental dengan analisis data secara deskriptif dan pengambilan data dilakukan secara retrospektif tahun 2020. Data yang digunakan antara lain data penggunaan terapi berdasar data rekam medis. Hasil yang diperoleh menunjukkan bahwa obat yang paling banyak diresepkan adalah golongan atipikal yakni Risperidon (44,32%). Sedangkan untuk peresepan kombinasi terdapat kombinasi terbanyak yakni Risperidon-Klozapin (34 kali atau 47,89%).
Front Cover, Editorial Information, Table of Content, Author Guideline, Back Cover Journal Editor
Jurnal Sains dan Kesehatan Vol. 4 No. 2 (2022): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v4i2.1152

Abstract

Profil Penyakit Periodontal di Rumah Sakit Umum Daerah Abdoel Wahab Sjahranie Samarinda: Periodontal Diseases Profile in Abdoel Wahab Sjahranie Hospital Nida Ulfah; Sinar Yani; Nuryanni Dihin Utami
Jurnal Sains dan Kesehatan Vol. 5 No. 4 (2023): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v5i4.1157

Abstract

Periodontal disease is one of the diseases affecting teeth and gum with high prevalence globally, indicated by inflammation on gingiva, alveolar bone, cementum and periodontal ligaments. This study aimed to finding out the profile of periodontal disease in the RSUDAWS from 2016-2020. This study is descriptive observational, which was conducted by collecting the medical records of patients from 2016-2020. 130 samples were collected through purposive sampling. This study results showed that chronic periodontitis was the most periodontal disease classification was 70 patients (53,8%), the highest number of patients were female as 71 patients (54,6%). Most patients were found in the age group of 17-25 years old with 35 patients (26,9%). Private workers were found to experience the disease the most, with 57 patients (43,8%). Patients with senior high school educational background noted as high, with 73 patients (56,2%), and the most systemic illnesses found in the periodontal patients were nasopharyngeal carcinoma with 17 patients (13,1%). Abdoel Wahab Sjahranie Hospital is a highest referral hospital in Kalimantan Timur Province tends to have low cases of periodontal disease with a higher severity cases of periodontal disease than other health provider in this region. Keywords: profile, periodontal disease, gingivitis, periodontitis Abstrak Penyakit periodontal merupakan penyakit pada gigi dan mulut dengan prevalensi tinggi yang ditandai adanya inflamasi pada gingiva, tulang alveolar, sementum, dan ligamen periodontal. Penelitian ini bertujuan untuk mengetahui profil penyakit periodontal di Rumah Sakit Umum Daerah Abdoel Wahab Sjahranie Samarinda (RSUDAWS) tahun 2016-2020. Penelitian ini bersifat observasional deskriptif yang dilakukan dengan mengumpulkan data rekam medis pasien penyakit periodontal tahun 2016-2020. Data diperoleh sebanyak 130 kasus dengan teknik purposive sampling. Hasil penelitian didapatkan jenis penyakit periodontal yang banyak ditemukan pada penelitian ini adalah chronic periodontitis sebanyak 70 orang (53,8%), jenis kelamin terbanyak adalah perempuan sebanyak 71 orang (54,6%), rentang usia pasien terbanyak adalah 17-25 tahun sebanyak 35 orang (26,9%), pekerjaan pada pasien terbanyak adalah swasta, yaitu 57 orang (43,8%), tingkat pendidikan pasien terbanyak adalah SMA sebanyak 73 orang (56,2%), dan penyakit sistemik penyerta terbanyak yang dialami pasien penyakit periodontal adalah karsinoma nasofaring sebanyak 17 orang (13,1%). RSUDAWS sebagai rumah sakit rujukan tertinggi di provinsi Kalimantan Timur cenderung mendapatkan kasus penyakit periodontal yang lebih sedikit dengan tingkat keparahan kasus penyakit periodontal yang lebih tinggi dibandingkan fasilitas kesehatan lainnya di wilayah tersebut. Kata Kunci: profil, penyakit periodontal, gingivitis, periodontitis
Pola Pengobatan Covid-19 pada Pasien Komorbid di RSUD dr. La Palaloi: The Pattern of Treatment for Covid19 in Comorbid Patients at the dr. La Palaloi Hospital Dwi Fitrah Wahyuni; An Nisaa Nurzak; Arifuddin Yunus; Nabilah Baharuddin; Sitti Nur Intang
Jurnal Sains dan Kesehatan Vol. 4 No. 5 (2022): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v4i5.1158

Abstract

As stated by the World Health Organization (WHO) as a global pandemic on March 11, 2020, Coronavirus Disease 2019 (Covid-19), a disease caused by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), [1]. For suspected and confirmed Covid-19 patients with mild symptoms, the use of antibiotic drugs is not recommended, both for therapy and prevention [2] .After WHO declared Covid-19 a global pandemic, RSUD dr. La Palaloi is one of the hospitals appointed by the government as a referral hospital for handling Covid-19 in Maros district, South Sulawesi. Comorbidity is one of the factors that causes the mortality rate in patients infected with Covid-19 to increase. The purpose of this study was to describe the pattern of prescribing Covid-19 drugs for comorbid patients. The research method used is a retrospective research method to determine the pattern of Covid-19 treatment with comorbid patients at dr. La Palaloi. The most common comorbidity is hypertension. The most antibiotics given to Covid-19 patients were Azithromycin and the most Antibiotics were Oseltamivir. Treatment for the first Covid-19 patient was given antibiotics and antivirals. Treatment for antihypertensives is the CCB group, for the treatment of diabetes is insulin, and for the treatment of bronchopneumonia, antibiotics are given.
Efektivitas Deferasirox pada Pasien Thalasemia Mayor: Artikel Review: Efficacy of Deferasirox for Thalassemia Mayor: Review Article Naksa Garnida Arfie; Bambang Subakti Zulkarnaen; Sudarmanto Sudarmanto
Jurnal Sains dan Kesehatan Vol. 4 No. 3 (2022): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v4i3.1159

Abstract

Thalassemia is a heterogeneous grouping of genetic disorders resulting from decreased synthesis of the alpha or beta chains of hemoglobin. Anemia and iron overload are the main causes of morbidity and mortality due to thalassemia disease. Iron chelation has improved the survival and quality of life of patients with thalassemia major. Deferasirox (DFX) was developed as monotherapy for the treatment of transfusion iron overload. Search data in this literature study using an electronic database, namely Science Direct, Pubmed with the keywords thalassemia, deferasirox and efficacy. The search results obtained 1015 articles and 5 articles that matched the inclusion and exclusion criteria. The total patients in this study were 410 people from 5 countries. The results of the review article found that deferasirox was effective in reducing iron in the body as seen from the LIC (Liver Iron Concentration), T2* heart and serum ferritin in patients with thalassemia major.
Kajian Interaksi Obat pada Pasien Gagal Ginjal Rawat Inap di RSUD Panglima Sebaya Tanah Grogot: Drug Interaction Studies in Patients with Kidney Failure Inpatient at Panglima Sebaya Hospital, Tanah Grogot Nurul Handayani; Muhammad Faisal; Rolan Rusli
Jurnal Sains dan Kesehatan Vol. 5 No. 4 (2023): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v5i4.1168

Abstract

Patients with acute and chronic kidney failure generally have accompanying diseases so many drugs are often prescribed. The increasing complexity of the drugs used will lead to an increased risk of drug interaction events, potentially affecting the success of the patient's therapy. This study aims determine the potential of drug interactions of patients with kidney failure inpatient of Panglima Sebaya Hospital. This research is a descriptive study retrospectively with purposive sampling techniques. The results of the study of 64 medical records of patients who qualified for inclusion showed that the characteristics of the most patients were men as many as 34 patients (53.13%), ages ranging from 46-55 years (early elderly) as many as 19 patients (29.69%), with the number of diseases accompanying 1-2 diseases as many as 50 patients (78.13%) such as anemia as many as 27 patients (28.13%). The total use of 6-10 drugs was mostly given to 31 patients (48.44%) in the form of cardiovascular system drugs which is 149 prescribing (31.17%). The potential drug interactions found were 12% minor, 80% moderate, and 8% major. Keywords: Kidney failure, Drug interaction, Treatment pattern Abstrak Pasien gagal ginjal akut maupun kronik umumnya memiliki penyakit penyerta sehingga banyak obat yang sering diresepkan. Meningkatnya kompleksitas obat yang digunakan akan menyebabkan peningkatan resiko kejadian interaksi obat, yang secara potensial mempengaruhi keberhasilan terapi pasien. Penelitian ini bertujuan untuk mengetahui potensi interaksi obat pada pasien gagal ginjal rawat inap di RSUD Panglima Sebaya. Penelitian ini merupakan penelitian deskriptif secara retrospektif dengan teknik purposive sampling. Hasil penelitian 64 rekam medik pasien yang memenuhi syarat inklusi menunjukkan bahwa karakteristik pasien terbanyak adalah laki-laki sebanyak 34 pasien (53,13%), usia rentang 46-55 tahun (lansia awal) sebanyak 19 pasien (29,69%), jumlah penyakit penyerta 1-2 penyakit sebanyak 50 pasien (78,13%) dengan penyakit penyerta yaitu anemia sebanyak 27 pasien (28,13%). Jumlah penggunaan 6-10 obat paling banyak diberikan kepada 31 pasien (48,44%) berupa obat sistem kardiovaskular yaitu 149 peresepan (31,17%). Potensi interaksi obat yang ditemukan yaitu 12% minor, 80% moderate, dan 8% major. Kata Kunci: Gagal ginjal, Interaksi obat, Pola pengobatan
Eksplorasi Obesitas Sebagai Faktor Komorbid Covid-19: A Systematic Review: Exploration of Obesity as a Comorbid Factor of Covid-19: A Systematic Review Mukhlidah Hanun Siregar; Mustika Arumbinang; Junengsih Junengsih
Jurnal Sains dan Kesehatan Vol. 4 No. 5 (2022): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v4i5.1169

Abstract

Obesity is one of the comorbidities of COVID-19 which has been widely reported to have an effect on the care patients needed. This study was carried out using a Systematic Review approach to explore the effects and mechanisms that occur due to obesity in COVID-19 patients. A total of 23 articles were reviewed after selecting on various predetermined article criteria. The results shown that there was a contribution of obesity in COVID-19 patients based on the type of treatment, length of treatment, need for intensive care, severity and increased risk of death. It is recommended to maintain a healthy lifestyle while maintaining a normal weight and doing physical activity and exercise every day with a minimum duration of 30 minutes. Thus, it can reduce the accumulation of macrophages in adipose tissue, so if infect COVID-19 do not cause a cytokine storm because chronic inflammation due to obesity.

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