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Science and Community Pharmacy Journal
Published by Sekolah Tinggi Ilmu Kesehatan Telogorejo Semarang
ISSN : -     EISSN : 28306139     DOI : 10.63520
Core Subject : Health,
Health Professions Medicine & Pharmacology
The scope of the journal is Pharmaceutical Technology and Analysis,Phamacology, Toxicology and Pharmacokinetics, Social Behavior, Administrative Pharmacy, Pharmacoeconomics,Pharmacognosy and Phytochmistry,Herbal medicines and complementary therapy, Clinical Pharmacy
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 31 Documents
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The Effect of the Addition of Virgin Coconut Oil (Vco) on the Physical Stability of Carrot Sunscreen Preparations (Daucus carota L.) Kalsum, Ummi; Nihlatunnaja, Nadiya; Firstca Aulia Rachma
Science and Community Pharmacy Journal Vol. 2 No. 1 (2023): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v2i1.354

Abstract

UV rays have harmful side effects of free radicals, dry skin can reduce the body's defenses against the effects of free radicals, antioxidants have activity as a free antiradical, Carrots have antioxidant activity due to the presence of carotenoid compounds, Fatty acid content from VCO which has the function of softening and moisturizing the skin.This study aims to determine the effect of the addition of Virgin Coconut Oil (VCO) on physical stability in the formulation of carrot sunscreen cream preparations. As well as Knowing the effectiveness of antioxidants on carrot tubers. Research methods test the physical characteristics of the preparation (organoleptic, pH, homogeneity, adhesion and dispersion), Cycling test cream stability test and in the onewayanova test.The results of the study obtained the influence of the stability of oily texture and rancid odor in formula III (21%) and based on data analysis, the higher the concentration, the wider the distribution power of the preparation and the decrease in the adhesion of the preparation. Conclusion The addition of Virgin Coconut Oil (VCO) affects the stability of texture and smell in formula III (21%) and based on data analysis the addition of Virgin Coconut Oil (VCO) to carrot sunscreen cream (Daucus carota L.) the higher the concentration the wider the dispersal power of the preparation and the decrease in adhesion of the preparation.
Total Flavonoid Content (TFC) and Antioxidant Activity of Carrot Extract Isolate (Daucus carota L.) Nadiya Nihlatunnaja; Kalsum, Ummi; Sa’adah, Anifatus
Science and Community Pharmacy Journal Vol. 2 No. 1 (2023): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v2i1.356

Abstract

Antioxidants are antiradical compounds that can neutralize reactive free radicals into non-reactive ones that are relatively more stable so as to protect cells from the harmful effects of free radicals. Carrots have antioxidant activity due to the presence of carotenoid compounds. This study aims to determine the antioxidant activity of carrots. Extraction research method with maceration method. Isolation of flavonoids by column chromatography method. Antioxidant activity test using FRAP method. The results of research conducted from 60 extract fractions obtained 10 flavonoid fractions with a %TFC value 5,332%; 5,242%; 6,742%; 7,475%; 6,829%; 5,896%; 5,282%; 6,191%; 5,450%; and 5,498%. IC50 3,920; 1,960; 2,096; 2,065; 1,846; 0,867; 3,517; 1,179; 3,383; dan 3,570 ppm. In conclusion, the antioxidant activity of the ten fractions was very strong (<50 g/mL).
Isolation Of Moringa Leaf Flavonoids (Moringa Oleifera L.) Using Column Chromatography Sa'adah, Anifatus; Ovikariani
Science and Community Pharmacy Journal Vol. 2 No. 1 (2023): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v2i1.357

Abstract

Preface : Moringa oleifera L. is one plant that contains secondary metabolite compounds such as alkaloids, steroids, tannins, saponins, anthraquinones, terpenoids, and flavonoids. Flavonoids donate their hydroxyl groups to inhibit free radicals. Purpose :This study aimed to isolate flavonoid compounds from Moringa leaf ethanol extract. Method : Extraction was carried out by maceration method and continued isolation using Column Chromatography method with n-butanol: acetic acid: water (4: 1: 5) eluent. Isolate results were identified by TLC, spectro, and FTIR. Result : FTIR analysis on fraction 5 contains flavonoid derivative compounds. Conclusion : It is flavonols with a purity of quercetin of 77.99%.
Formulation of Yodium Leaf Extract (Jatropha Multifida L.) Cream for Cuts Healing in Wistar Male Rats (Rattus novergicus) Tunik Saptawati; Eka Lidia Sari; Novita Dwi Dahliyanti
Science and Community Pharmacy Journal Vol. 2 No. 1 (2023): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v2i1.358

Abstract

Yodium plant (Jatropha multifida L) has pharmacology effect as antibacterial, antioxidant, and anti-inflammatory. Yodium plant contain chemical compounds, namely alkaloids, flavonoids, phenols, and tannins which have benefits in helping the healing process of cuts. The aim of this study was to determine the difference in wound healing time in rats (Rattus norvegicus strain wistar) using Yodium leaf extract cream with concentrations of 5%, 10%, and 15%. This research is a true experiment. The cuts healing were carry out on Wistar male rats that smeared by yodium leaf extract cream and be observed its healing process. The cream preparations were tested for physical quality including organoleptic test, homogeneity, pH test, spreadability test, adhesion test, and viscosity test. The results of the organoleptic test of the three formulas have a green color, distinctive aroma, and semi-solid consistency. Test the homogeneity of the three homogeneous preparations. The pH test of the three cream preparations met the pH test requirements of 4-8. Spreadability test, the three cream preparations met the requirements of 4-7 cm. In the adhesion test, the three preparations met the requirements of 2-300 seconds. The cream was applied to the backs of 0.1-gram rats with use three times a day. Coral plant (Jatropha multifida L) has healing effectiveness againts cuts in white rats (Rattus novergicus strain wistar). The cream preparation with 15% concentration of yodium leaves extract concentration was more effective in the wound healing process for 9 days. Keywords : Yodium leaf extract (Jatropha multifida L), Cream, Cuts, healing process
An Overview of Knowledge of Traditional Medicine Among Ponggalan Community, Giwangan, Umbulharjo, Yogyakarta Rahmawati, Amanda Lista; Qarriy Aina Urfiyya
Science and Community Pharmacy Journal Vol. 2 No. 2 (2023): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v2i2.417

Abstract

Abstract: Preface Traditional medicine is a material or natural ingredients used for traditional medicine. The use of traditional medicine in Indonesia is 49.5%, namely in the form of herbs. Many people use traditional medicine, but knowledge regarding the use of traditional medicine is still lacking. Many people in Ponggalan RW 05, Giwangan, Umbulharjo, Yogyakarta use traditional medicine, especially the elderly. Purpose : Knowing the description of the level of public knowledge about traditional medicine in Kampung Ponggalan RW 05, Giwangan, Umbulharjo, Yogyakarta.. Method : This research is a type of observational research that is descriptive in nature using a research instrument in the form of a questionnaire. Result : Description of the level of knowledge in Kampung Ponggalan RW 05, Giwangan Village, Umbulharjo District, Yogyakarta in January 2023 as many as 28 respondents (35%) with a good level of knowledge, as many as 42 respondents (53%) with a sufficient level of knowledge, and 10 respondents have a good level of knowledge less (13%). Conclusion : The level of knowledge of the Ponggalan community, Giwangan Village, Umbulharjo District, Yogyakarta about traditional medicine are sufficient.
Stability Testing Occurred On Piroxicam Cream Preparation By Using Stearic Acid And Triethanolamine As Emulsifying Agents Aldila, Silvy; Girsang, Valentina; Rahmawati, Ina Sonia; Maharai, Daniel; Sa’adah, Anifatus
Science and Community Pharmacy Journal Vol. 2 No. 2 (2023): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v2i2.482

Abstract

Preface: Piroxicam is classified as a Class 2 product in the Biopharmaceutic Classification System due to its limited solubility in water. The cream preparations underwent optimisation of the stearic acid and triethanolamine concentrations. The optimisation results indicate that the most favourable amounts of stearic acid and triethanolamine (TEA) are 16% and 4% respectively. The physical attributes test yielded positive findings for the formula, indicating a successful cream formulation that satisfied the specified criteria. Purpose: The cream formulation is thereafter submitted to a stability assessment. The purpose of the stability test is to ascertain the long-lasting quality of the preparation when subjected to various storage circumstances. Procedure: Stability tests were conducted over 6 cycles at temperatures of 4° C and 40° C. During the testing phase, various characteristics of the cream preparation were assessed, including organoleptic properties, homogeneity, viscosity, adhesive power, spreadability, and pH. Result: The formulated solution successfully fulfils the criteria of the physical characteristics test, with the following parameter values: pH of 6.8, viscosity of 11010 Cps, spreading power of 6.8 cm, adhesive power of 2.6 seconds, and protective power of 6.5 seconds. Conclusion: The t-test findings conducted before and after assessing the stability of the preparation indicated a p-value greater than 0.05, indicating the absence of a significant difference.
Validation Of Analysis Method For Determining Content Of Chlorpheniramine Malate (Ctm) In Tablet Preparation By Uv Spectrophotometry Sa'adah, Anifatus
Science and Community Pharmacy Journal Vol. 2 No. 2 (2023): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v2i2.483

Abstract

Abstract: In the pharmaceutical industry, quality control of a medicine is one part of Good Medicine Manufacturing Practices (CPOB) which is used to ensure that the product has quality that is appropriate for its intended use, so that the production results marketed meet the CPOB requirements. Therefore, this study aims to determine the levels of the active substance chlorpheniramine maleate (CTM) in drug samples and compare them with standards using UV spectrophotometry. The research results showed that the maximum CTM wavelength measurement obtained was 263 nm. The linear equation y = 0.01904x + 0.03139 with a correlation coefficient (R) value of 0.995. The SD obtained by sample A was 0.4483 and the % relative standard deviation (%RSD) value was 14.6%, sample B was 0.2020 and the % relative standard deviation (%RSD) value was 6.4%, sample C was 0.0542 and the % relative standard deviation (%RSD) value is 1.3%. The LOQ values obtained on samples A, B and C are not accepted as quantitation limits because they do not meet precision (CV < 20%) and accuracy (bias < ±20%). The average % recovery results obtained for samples A, B, and C were 100%. The range of CTM levels obtained was 159.307%, 145.025%, and 126.195%. Keywords: UV Spectrophotometry, Chlorpheniramine maleat, Validation of analytical methods
Implementation Of FMEA On The Potential Of Medication Error In Pharmaceutical Services In Bonang II In Primary Health Care Demak Regency Suwarni, Sri; Haryanti, Nur; Gloria, Fransisca
Science and Community Pharmacy Journal Vol. 2 No. 2 (2023): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v2i2.484

Abstract

Pharmaceutical service is one of the high risk areas in supporting the quality of health services, not least in the pharmacy service at Puskesmas. Failure Mode and Effect Analysis (FMEA) is one method that can be used to detect the existence of medication error, so it can be designed an action to minimize the risk of medication error in the pharmaceutical service. This research is a research action researched by applying FMEA method. This research was conducted in cross sectional, with prospective data taking on recipes in Pharmacy Room of Puskesmas Bonang II of Demak Regency in December 2017 and post implementation in February 2018. FMEA method in this research is expected to minimize the possibility of medication error in pharmacy service at Puskesmas Bonang II of Demak Regency. Through the FMEA method known RPN value before implementation for failure to read dosage dosage on an incomplete prescription is 420, the RPN value for failure to read the name of the drug on an unclear prescription is 486, in the failure mode fault filed the drug RPN value before implementation is 360. Measures implemented under the FMEA are the application of Standard Operating Procedure (SOP) prescribing, agreement on the use of abbreviations in recipes and the use of medicinal information systems of Puskesmas. The result of evaluation after FMEA implementation is reduced RPN value on failure to read dosage dose to 280, RPN value for failure to read drug name after implementation to 378, and failure mode error of taking drug name RPN value to 270.
Ethnobotanical And Ethnopharmacological Study Of Plants Used By The Dumagat Tribe In Angat Dam Watershed, Norzagaray, Bulacan, Philippines Lopez, John Angelo G; Camacho, Larien D; Dela Cruz; Rachelle T.; Perez, Kareen M; Tumale, Ara Nicole G; Jazul, Regina A.
Science and Community Pharmacy Journal Vol. 2 No. 2 (2023): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v2i2.485

Abstract

This research on Ethnobotanical and Ethnopharmacological study is a documentation of plants used by the Dumagat Tribe in Angat Dam Watershed, Norzagaray, Bulacan, Philippines. The researchers used snowball sampling technique as a method to identify potential subjects of the study. A total of 100 respondents were interviewed using validated semi-structured questionnaire including the demographic profile of respondents, together with the Ethnobotanical and Ethnopharmacological data of plants. It was noted that most of the respondents are aged between 51-59 years old, majority were male, married, catholic, with rattan making as their source of livelihood. 124 plants were collected and presented to the respondents and noted that leaves was the most frequently used part. The use value (UV), fidelity level (FL), and informant consensus factor (ICF) were calculated for each plant species used to treat various ailments. The plant with the highest use value was Blumea balsamifera (0.69) and the maximum fidelity level of 100% was found for 23 plant species. In the case of ICF, the highest value of 0.9501 was cited for diseases of the respiratory system. The wide variety of plants documented in Angat Dam Watershed can open path for furnishing novel information leading to future studies that would provide recognition of this undocumented knowledge to improve healthcare.
Impact Of Work Life Balance On The Well-Being Of Pharmacist In Various Pharmaceutical Sectors Estrella, J.P.; Khojasteh, A.; Suarez, M.A.C.; Jazul, Regina A.
Science and Community Pharmacy Journal Vol. 2 No. 2 (2023): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v2i2.486

Abstract

Work-life balance (WLB) describes the ideal of splitting one's time and energy between work and other important aspects of their life. This study would benefit individuals and organizations to have a deeper understanding of the importance of a healthy balance between work and family demands and their effects on people’s wellbeing and organization’s performance. Quantitative research method was used, and respondents were selected through convenient sampling technique. The survey questionnaire with a Cronbach’s alpha of 0.87 was distributed to 150 respondents but only 138 were returned giving an overall returning rate of 92%. From the gathered data it was found that “flexibility in time” as the most available work-life balance benefits, while “socializing and leisure activities during weekend in order to maintain family relationship” were the problem frequently experienced. However, “respondents’ time needed at home” is the most conflict that interferes at work while, “work related duties” sometimes create a conflict with family activities. In conclusion, Work-life balance does not have impact on Family Satisfaction (r=0.11953) and Work Satisfaction (0.08541) but has minimal impact with Psychological Health (0.28).

Page 2 of 4 | Total Record : 31

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