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Fransisca Gloria
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Science and Community Pharmacy Journal
Published by Sekolah Tinggi Ilmu Kesehatan Telogorejo Semarang
ISSN : -     EISSN : 28306139     DOI : 10.63520
Core Subject : Health,
Health Professions Medicine & Pharmacology
The scope of the journal is Pharmaceutical Technology and Analysis,Phamacology, Toxicology and Pharmacokinetics, Social Behavior, Administrative Pharmacy, Pharmacoeconomics,Pharmacognosy and Phytochmistry,Herbal medicines and complementary therapy, Clinical Pharmacy
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 31 Documents
 1   2   3   4 
THE RELATIONSHIP BETWEEN LEVEL OF KNOWLEDGE AND COMMUNITY ATTITUDES ABOUT TRADITIONAL MEDICINE IN MAJASEM HAMLET, MADUREJO SUB-DISTRICT, PRAMBANAN SLEMAN SUB-DISTRICT Nur Selfia Kurniasari; Qarriy Aina Urfiyya
Science and Community Pharmacy Journal Vol. 3 No. 1 (2024): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v3i1.489

Abstract

Abstract: Preface : The use of traditional medicine in Indonesia continues to increase. In the Special Region of Yogyakarta, the use of traditional medicines is quite high, reaching 58.1% in 2013. However, the community's knowledge of traditional medicines is still low and limited to herbal medicine. Purpose : To describe the level of knowledge, attitudes and the relationship between knowledge and attitudes towards traditional medicines. Method : This research using analytic observational design with a cross sectional technic. The sampling technique used purposive sampling on 70 respondents in Majasem Hamlet, Madurejo Village, Prambanan District, Sleman. The data observed included patient characteristics (age, gender, education and occupation), level of knowledge, attitudes, and the relationship between the level of knowledge and attitudes towards traditional medicines, using the Kruskal-Wallis statistical test. Result : In this study, there were more female respondents than male respondents, namely 62%. The most age was the age group of 17-25 years (31%). Meanwhile, the most levels of education and occupation were housewives (34%) and high school (61%). The majority of the community's level of knowledge about traditional medicine was in the sufficient category (50%), the attitude towards the use of traditional medicine was in the majority in the good category (84.2%). The Kruskal-Wallis test results obtained a significance value of 0.005 <0.05. Conclusion : The level of community knowledge about traditional medicine is in the good (28.5%), intermediate (50%), and poor (21.5%) categories. Attitudes to the use of traditional medicine were in the good (84.2%), intermediate (14.3%) and bad (1.5%) categories, and there was a relationship between the level of knowledge and attitudes towards traditional medicine. Keywords: traditional medicine, level of knowledge, attitude
BROCCOLI (Brassica oleracea L) ETHANOL EXTRACT: A MOISTURIZER AND ITS EVALUATION IN ASPECTS OF PHYSICAL CHARACTERISTICS Aldila, Silvy; Puruhita, Ranatri; Uliana, Syahkhirotul Exma; Sa’adah, Anifatus; Gloria, Fransisca
Science and Community Pharmacy Journal Vol. 3 No. 1 (2024): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v3i1.545

Abstract

Skin disorders that are dry, dull, scaly, and not fresh affect everyone. Moisturizing cream is a cosmetic product that effectively hydrates and improves dry skin. Broccoli, scientifically known as Brassica oleracea L, is rich in vitamin C components, vitamin E (α-tocopherol), and flavonoids, which act as natural antioxidants and provide moisturizing properties for the skin. Producing extracts by the maceration process. Broccoli extract is utilized in the formulation of four moisturizing cream preparation compositions, each with a concentration of F1 (0%), F2 (2%), F3 (3%), and F4 (4%). The moisturizing cream formulation is assessed for its physical properties. Conducting tests to evaluate the dosage characteristics of moisturizing creams, includes organoleptic testing, homogeneity testing, pH testing, dispersion testing, adhesion testing, and viscosity testing. The concentration of broccoli extract in the four moisturizing cream preparation formulations is as follows: F1 (0%), F2 (2%), F3 (3%), and F4 (4%). The moisturizing cream formulation is assessed for its physical properties. Conducting tests to evaluate the dosage properties of moisturizing creams, including sensory evaluation, uniformity assessment, pH measurement, dispersion analysis, adhesion examination, and viscosity measurement
LITERATURE REVIEW : Cost Effective Analysis of Sitagliptin for the Treatment of Diabetes Mellitus Type 2 Vidiani, Anak Agung Pradnya Paramitha; Puspitaningrum, Anisa Nova; Girsang, Valentina; Adrianto, Madyo
Science and Community Pharmacy Journal Vol. 3 No. 1 (2024): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v3i1.546

Abstract

Diabetes mellitus (DM) is a chronic disease characterized by increased glucose levels in the blood. The prevalence of type 2 DM is currently increasing. In pharmacological treatment, metformin is the first-line oral therapy for most patients with type 2 diabetes. Therapy with targeted incretin has been shown to stimulate glucose-dependent insulin secretion, reduce glucagon secretion, improve beta cell function, slow gastric emptying, increase satiety, reduce appetite, and provide general benefits beyond the pancreas. Search for scientific articles by utilizing internet searches through Google Scholar and PubMed. Using keywords related to "Cost Effective Analysis", "Diabetes Mellitus type 2", "Sitagliptine" with Boolean operator "AND". Sitagliptin is less cost-effective when compared to liraglutide. Sitagliptin is the first agent of the DPP-4 inhibitor with other substances following soon after. The evaluation shows that the prevention of complications in patients with type 2 diabetes and cardiovascular disease (CVD) in the SGLT2 inhibitor group is more recommended, namely empaglifozin as the second line compared to sitagliptin.
EFFORTS TO IMPROVE THE PERFORMANCE OF THE QUALITY CONTROL (QC) SECTION OF PT. X USING THE SIX SIGMA METHOD TO FOCUS ON RISK MANAGEMENT Suwarni, Sri; Gloria, Fransisca; Rustaman, Heri; Hidayah, Ravita Nur
Science and Community Pharmacy Journal Vol. 3 No. 1 (2024): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v3i1.549

Abstract

Introduction: The quality control (QC) process of a pharmaceutical company must be carried out following the Good Manufacturing Practices (CPOB) guidelines. Evaluation of the QC process in the pharmaceutical industry needs to be carried out to minimize notes and risks that could affect the final results of the tests carried out. Six Sigma and risk management can be used to identify defects and risks in the quality control processes carried out. The Six Sigma and risk management methods were used in this research to improve the performance of the pharmaceutical company PT. X in the Quality Control (QC) section. Method: The method used in this research is an observational method with primary and secondary data types. Data collection is carried out by interviews, observation, and documentation that focuses on defects and risks in the QC process. Data analysis uses the Six Sigma method with DMAIC stages and SPSS 25 statistical tests. Results: results of the risk management performance values of the PT QC section. X decreased by 7.7% with a DPMO value from 328,000 to 251,200 and the Six Sigma value increased from 1.95-sigma to 2.19-sigma. Statistical analysis using the SPSS 25 chi-square method shows a value of 0.005, which means there is a difference between the risk value before and after improvement. The results of the contingency coefficient test show a value of 0.803 (close to 1), which means the data obtained has a strong relationship. The data results show an increase in the performance of the Quality Control (QC) section of PT. X which can be seen from the risk value, DPMO, and sigma value
VALIDITY AND RELIABILITY OF KNOWLEDGE AND HEALTH BELIEF MODEL (HBM) IN PULMONARY TUBERCULOSIS PATIENTS AT KEDUNGMUNDU AND TLOGOSARI WETAN COMMUNITY HEALTH CENTERS IN SEMARANG CITY Cahyanti, Pipit; Al Farizi, Gilang Rizki; Arini, Yovita Dwi
Science and Community Pharmacy Journal Vol. 3 No. 1 (2024): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v3i1.550

Abstract

Tuberculosis (TB) is a contagious disease caused by a Mycobacterium tuberculosis infection, also known as acid-fast bacteria. To achieve a cure for TB patients, it is possible to increase knowledge and treatment compliance behavior. The Health Belief Model (HBM) is an effective treatment widely used to improve compliance and health behavior. This study aims to measure the validity and reliability of the knowledge construct and the HBM in pulmonary tuberculosis patients at the Kedungmundu Health Center and Tlogosari Wetan Health Center, Semarang City. This research adopted a quantitative observational design with a cross-sectional approach. The results show that the validity test was based on the corrected item value of 0.361, while the reliability test used internal consistency techniques on the Cronbach Alpha value of 0.70. Meanwhile, the results of the knowledge construct had a validity value of 13 items with a corrected item value of 0.361 and reliability with a Cronbach's alpha value of 0.796. Also, the HBM construct to measure compliance and behavior had a validity value of 20 items with a corrected item of 0.361 and reliability with a Cronbach's alpha of 0.817.
A RELATIONSHIP BETWEEN COMPLIANCE IN DRUG USE AND THE SUCCESS OF ANTIHYPERTENSION THERAPY IN THE INSTALLATION OUTPATIENT CARE AT TAWANGSARI COMMUNITY HEALTH CENTER, SUKOHARJO: RELATIONSHIP BETWEEN COMPLIANCE IN DRUG USE AND THE SUCCESS OF ANTIHYPERTENSION THERAPY IN THE INSTALLATION OUTPATIENT CARE AT TAWANGSARI COMMUNITY HEALTH CENTER, SUKOHARJO Epaphroditus , Brian; Ovikariani; Retnowati
Science and Community Pharmacy Journal Vol. 3 No. 2 (2024): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v3i2.578

Abstract

Abstract: The high incidence of hypertension in Indonesia is not followed by patient compliance in taking medication. The determinant of successful therapy is compliance with medication use. Low compliance levels cause problems such as increasing rates of chronic diseases and their complications. In 2019, the Tawangsari Sukoharjo Health Center was ranked eighth in Sukoharjo Regency with the largest number of hypertension patients, namely 1,583 people. This study aims to determine the relationship between drug compliance and the success of therapy in hypertension patients at the outpatient installation of Tawaangsari Health Center, Sukoharjo. This study is a descriptive observational study with a cross-sectional approach. Data collection was carried out using a purposive sampling method using the ASK-12 questionnaire in hypertensive patients who met the inclusion criteria. The research data were analyzed using chi-square statistics. The results showed that patients with high compliance were 45.7% while low compliance was 54.3%. The success rate of therapy was 55.7% of patients succeeded and 44.3% of patients failed. The results of the chi-square test showed a P value of 0.026 (P <0.05), which means that there is a relationship between compliance and the success of antihypertensive therapy in outpatient settings at the Tawangsari Health Center Keywords: Compliance level ; antihypertensive therapy ; therapeutic success
An Irritation Test of Optimum Preparation of Celery Extract Face Clay Cleanser With Sodium Lauryl Sulfate (SLS) and Cocamidopropyl Betaine (CAPB) as Surfactants: Irritation Test of Optimum Preparation of Celery Extract Face Clay Cleanser With Sodium Lauryl Sulfate (SLS) and Cocamidopropyl Betaine (CAPB) as Surfactants Bunga Eloystina, Laurencia Julia; Aldila, Silvy; Girsang, Valentina; Sa'adah, Anifatus
Science and Community Pharmacy Journal Vol. 3 No. 2 (2024): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v3i2.580

Abstract

Surfactant is one of the important things in making face clay cleanser preparations. Sodium Lauryl Sulfate (SLS) is an anionic type surfactant that is often used in cosmetic products. The use of Sodium Lauryl Sulfate (SLS) can cause irritation and dry skin. Combination with cocamidopropyl betaine (CAPB) which is amophoteric can reduce skin irritation. Based on this, a safety test is needed which aims to meet the preparation requirements before being marketed to the wider community. One of the safety tests that can be done is the skin irritation test. The test method used is the human patch test. The irritation test of the optimum preparation of face clay cleanser celery herb extract (Apium graviolens L.) with a concentration of 0.5% SLS and 9.5% CAPB was carried out on 6 volunteers consisting of men and women aged 20-35 years, the score of the degree of irritation was 0, which means that the preparation is not irritating. Based on the evaluation with SPSS, it can be concluded that there is no significant difference (p>0.05) for the irritation test results and the optimum preparation of celery herb extract face clay cleanser (Apium graviolens L.) meets the safety requirements.
A Literature Review: Effectiveness of NSAIDs in Osteoarthritis Patients Adrianto, Madyo; Anak Agung Pradnya Paramitha Vidiani; Puspitaningrum, Anisa Nova; Girsang, Valentina
Science and Community Pharmacy Journal Vol. 3 No. 2 (2024): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v3i2.582

Abstract

Pain, stiffness, swelling, and decreased joint function are some of the clinical signs of osteoarthritis, a disease that affects numerous anatomical and physiological aspects of joint tissue, cartilage degradation, bone remodeling, and osteophyte development. This literature review's objective is to ascertain the efficacy of NSAIDs in osteoarthritis by searching for journals from PubMed.. The method used was to search for articles through pubmed using the keywords "NSAID", "osteoarthritis", "Therapy" with a filter added for the last 5 years (2019-2024) obtained 103 articles. Then with the keywords "NSAID", "osteoarthritis", "therapy", "efficacy" obtained 71 articles. After analysis, there are 13 journals that can be include into inclusion requirement. NSAIDs preparations are particularly helpful for osteoarthritis therapy, both in knee and hip osteoarthritis. NSAIDs medications in a variety of dose forms, including oral, topical, spray, injection and plaster, are useful in relieving pain in osteoarthritis patients
AN ANALYSIS OF FLAVONOID COMPOUNDS FROM ETHANOL EXTRACT OF MORINGA LEAVES (MORINGA OLEIFERA L.) USING FTIR AND HPLC Puruhita, Ranatri; Sulistyoningsih, Danik; Kristiyanti, Winnie; Aulia Rachma, Firstca
Science and Community Pharmacy Journal Vol. 3 No. 2 (2024): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v3i2.583

Abstract

Moringa leaves contain flavonoids, phenols, tannins, alkaloids, saponins, terpenoids, and steroids. The flavonoid and phenol content has antioxidant activity. This research aimed to determine compounds in the ethanol extract of Moringa leaves To determine the type of flavonoid content using FTIR and HPLC. FTIR analysis shows that Moringa leaves possibly contain compounds from quercetin derivatives, which is supported by HPLC analysis. This quercetin compound is a group of flavonols that are characterized by the presence of a hydroxyl group and a carbonyl group. HPLC analysis was carried out by making a quercetin standard with a concentration of 200 ppm. The resulting wavelength is 254 nm. The results of the quercetin standard chromatogram which contains one main peak obtained from the quercetin standard. This peak shows the retention time at 3 minutes. The results of the standard chromatogram, quercetin has an outer area of ​​44763473 and a sample area of ​​17455781 with 2 times dilution, so the % purity of fraction 9 for quercetin is 77.99 ppm. This HPLC analysis shows that Moringa leaves probably contain quercetin derivatives which are characterized by the same retention time between the sample and the quercetin standard, namely at a retention time of 3 minutes, and have a peak pattern that is almost the same as the quercetin standard.
Evaluasi Sistem Pengendalian, Pencatatan dan Pelaporan Sediaan Farmasi Di Apotek Wilayah Semarang Barat Belkis Nur Addini; Fransisca Gloria; Gilang Rizki Al Farizi; Ovikariani Ovikariani
Science and Community Pharmacy Journal Vol. 3 No. 2 (2024): Science and Community Pharmacy
Publisher : STIKES Telogorejo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63520/scpj.v3i2.663

Abstract

Obat dan sediaan farmasi lainnya yang dikelola dalam jumlah banyak, membutuhkan biaya yang besar dan biaya yang ditimbulkan akan meningkat jika pengendalian persediaan tidak tepat. Dengan demikian apotek sangat penting melakukan pengendalian persediaan agar dapat terciptanya suatu efisiensi dalam penggunaan modal. Stok Opname adalah suatu kegiatan pencatatan penggunaan obat dalam waktu satu bulan. Kegiatan tersebut dilaksanakan diawal atau akhir bulan namun pada pelaksanaannya sering kali terlambat dan ditemukan ketidak sesuaian antara kartu stok dan jumlah fisik obat. Ketidak sesuaian antara kartu stok dan jumlah fisik obat menyebakan laporan penggunaan obat yang tidak akurat. Hai ini dapat mempengaruhi perencanaan obat selanjutnya akan memberikan dampak pada ketersediaan obat di apotek. Penelitian ini bertujuan untuk mengevaluasi sistem pemusnahan dan penarikan sediaan farmasi alkes dan BMHP di apotek wilayah Semarang Barat. Penelitian ini bersifat deskriptif menggunakan rancangan cross sectional termasuk dalam penelitian non eksperimental dengan pendekatan kualitatif pengumpulan data dilakukan dengan observasi langsung terhadap sistem Pemusnahan dan Penarikan sediaan farmasi di beberapa apotek konvensional wilayah Semarang Barat. Hasil penelitian yang dilakukan pada 5 (lima) apotek mendapatkan persentase rata-rata sebesar 82.22%, nilai ini termasuk dalam kategori yang tergolong dalam rentang “sesuai” (>50%). Hal ini menunjukkan bahwa pada kelima apotek telah memenuhi Petunjuk Teknis Standar Pelayanan Kefarmasian Di Apotek Tahun 2019.

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