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Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine
Published by Universitas Lampung
ISSN : 26557800     EISSN : 2356332X     DOI : https://doi.org/10.23960/jka
Core Subject : Health,
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health
Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine is a peer-reviewed scientific journal published by the Faculty of Medicine, University of Lampung. This journal serves as a platform for disseminating research findings and scholarly discussions in the fields of medicine, public health, environmental health, and their intersections with agriculture and agromedicine. The journal emphasizes preventive, promotive, and educational health strategies, especially within rural and agrarian communities.
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 565 Documents
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THE EFFECTIVENESS OF GARLIC (Allium sativum L.) EXTRACT AS OVICIDE OF Aedes aegypti’s EGGS Apga Repindo; Endah Setyaningrum; Syazili Mustofa; Betta Kurniawan
Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine Vol. 1 No. 1 (2014): Jurnal Agromedicine
Publisher : Fakultas Kedokteran Universitas Lampung

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Background: The World Health Organization (WHO) noted to date approximately 50 million cases of dengue fever are found every year. Prevention efforts of vector of dengue fever have been carried out, that is using synthetic insecticides which gives negative effect for population, so natural insecticide is needed. One of them using garlics that contains allicin, saponin and flavonoid that can inhbit hatchability of Aedes aegypti’s eggs. This research objective was to know if garlics extract effective as the ovicide of Aedes aegypti’s egg.Methods: This experimental studies, which used completely randomized design, was performed in November 2013 in Laboratory of Zoology, Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Lampung. Concentration of the extract used was 0%, 0,1%, 0,3%, 0,5%, 0,7% and 1% with 4 repetitions for each treatment. Furthermore, was laid 20 eggs in each treatment and repetition, so was gotten the total number of samples of 480 eggs. Then, was observed number of eggs that did not hatch every 6 hours for three days. Hypothesis test using one- way ANOVA test and post hoc Bonferroni analysis.Results: At the end of the study, hypothesis test of one-way ANOVA resulted p-value<0,001. The results showed a decrease in hatchability of eggs of Aedes aegypti at concentrations of 0,1%, 0,3%, 0,5%, 0,7% and 1% compared to the negative control. In the post hoc Bonferroni analysis was known effective concentration compared to controls (0%) was 1%. The higher the concentration of the extract on the inhibition of hatching eggs will be higher as well.Conclussion: Garlic extract effective as the ovicide of Aedes aegypti’s egg. [J Agromed Unila 2014; 1(1):16-21] Keywords: Aedes aegypti, Allium sativum L., ovicide.
POTENTIAL OF AVOCADO (Persea americana mill) TO REDUCE CORONARY HEART DISEASE RISK Yuda Ayu Kusuma Wardani
Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine Vol. 1 No. 1 (2014): Jurnal Agromedicine
Publisher : Fakultas Kedokteran Universitas Lampung

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World Health Organization (WHO) in 2002 declared that the coronary heart disease (CHD) is the leading cause of death in the world. There are 16.7 million people died from cardiovascular disease or equal 30% of total deaths in the world. Results of a survey conducted by the Indonesia Ministry of Health stated that prevalence of CHD in Indonesia is increasing from year to year. In fact, since 2000s can be ascertained the tendency of the cause of death in Indonesia shifted from infectious diseases to cardiovascular diseases, including CHD and degenerative diseases. Avocado (Persea americana mill) contains ingredients such as monosaturated fatty acid (MUFA), pantotenat acid, selenium, amino acids, beta siterol, niacin, vitamin C and fiber that actively decrease risk of CHD. Many studies using experimental animals, in which fat-induced rats, were given avocado juice shown to lower total serum cholesterol levels significantly. The main mechanism of the avocado is by reducing levels of low density lipoproteins (LDL), triglycerides, very low density lipoprotein (VLDL), and increasing high density lipoprotein (HDL) cholesterol concentration in blood. [J Agromed Unila 2014; 1(1):55-60] Keywords: avocado, cholesterol, coronary heart disease
ANTIDIABETIC POTENTIAL OF SOURSOP LEAF EXTRACT (Annona muricata L.) AS A TREATMENT FOR TYPE 2 DIABETES MELLITUS Annisa Ratya
Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine Vol. 1 No. 1 (2014): Jurnal Agromedicine
Publisher : Fakultas Kedokteran Universitas Lampung

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Type 2 Diabetes Mellitus (DM) is a disease or chronic metabolic syndrome that marked by high level blood glucose with insulin insuficience. Indonesia has been the 4th largest diabetics in the world. The therapy of DM is oral antidiabetic, including expensive drugs with some side effects, so that herbal medicine begins to attract the attention. One of the herbal medicine that has been used as antidiabetic is soursop (Annona muricata L.), especially the leaf, because it become the most widely used plants as antidiabetic herbal. One of active compounds in soursop leaf that used as antidiabetic is tannin that can be hydrolyzed to gallotanin and ellagitanin which has insulin-like compound, and flavonoids, especially quercenin, to stimulate pancreatic insulin secretion and repair the damage of  β cells pancreas. Besides that both tannins and flavonoids are inhibitors of the α-glucosidase enzyme. The soursop leaf extract can be used as an alternative traeatment for type 2 DM.[J Agromed Unila 2014; 1(1):61-6] Keywords: quercenin, soursop leaf, tannin, type 2 diabetes mellitus
THE EFFECTS OF SCRAPPING TREATMENT TECHINIQUES FOR BODY HEALTH Fariz Fadly Tanjung
Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine Vol. 1 No. 1 (2014): Jurnal Agromedicine
Publisher : Fakultas Kedokteran Universitas Lampung

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Scraping treatment techniques are often referred to treatment that is simple and easy but has a healing effect which is quite fast compared to modern medicine. For the Javanese in particular, alternative treatment techniques through the scrapings considered more practical, inexpensive, rational, effective and proven. But actually what are the effects of this scraping treatment techniques so that becoming popular and able to survive in modern times. Kerokan or in modern medical termsis referred to scraping the skin with a body scrub that has a dull surface to redness on the skin. Scrapings treatment technique is not only well known in Java, in some other countries especially in Southeast Asia,many believes in the efficacy of the scrapings. Through histopathology, assessed whether there is damage to the skin and an increased in the volume of blood flow and hormone levels or chemical mediators in the body or not by scrapings experience. The results of several studies showed they are no damage to the skin, but local acute inflammatory occurs as normal reaction. There is an increasing blood flow perfusion due to the increased of metabolism rate. Biomolecular studies showed an increased in IL-1, C1q and β-endorphin as well as decreased in C3 and PGE2. [J Agromed Unila 2014; 1(1):67-71] Keywords: biomolecular, histopathology, inflamation, scrapping
THE UTILIZATION OF ETHANOL EXTRACT OF THE SOURSOP LEAVES (Annona muricata L.) AS BREAST CANCER CHEMOPREVENTIVE Karimah Ihda Husnayain; Asep Sukohar; Tiwuk Susantiningsih
Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine Vol. 1 No. 1 (2014): Jurnal Agromedicine
Publisher : Fakultas Kedokteran Universitas Lampung

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The breast cancer is the highest incidence and causes of women mortality in the world. It is estimated every year that 12 million people suffering from the cancer and 7,6 million of them died. Cancer treatment includes surgery, radiotherapy and chemotherapy have more side effects. The preventions is needed to reduce the incidence of breast cancer. Then, a natural materials anticancer is needed as an alternative chemopreventive such as soursop (Annona muricata L.) which contains anticancer. The active substance in the soursop which is capable of acting as an anticancer is annonaceous acetogenins. Acetogenins in soursop leaves could selectively attack cancer cell growth. Acetogenins consist of active compounds that has cytotoxic activity which works by inhibiting the transport of adenosine triphosphate (ATP) in the mitochondria of breast cancer cells. The soursop leaf extract contains acetogenins as an anticancer agents that can prevent the growth of cancer cells that can not be controlled by the body's defense mechanism, so it can be concluded that the leaf extract of soursop can be used as an alternative chemopreventive against breast cancer. [J Agromed Unila 2014; 1(1):72-6] Keywords: acetogenins, breast cancer, soursop (Annona muricata L.)
POTENCY OF CHITOSAN AS HEAVY METAL ADSORBENT FROM INDUSTRIAL WASTE EXPOSURE Sakinah Sakinah
Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine Vol. 1 No. 1 (2014): Jurnal Agromedicine
Publisher : Fakultas Kedokteran Universitas Lampung

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Nowadays, industries in Indonesia show progressing, such as chemistry, textile, home industry, agriculture, and others. It aims to increase prosperity of society, but it produce side products, an industrial waste. Industrial waste has negative effects to environment and human’s life. Chemistry materials that used in metal industries are toxic, which is dangerous for human’s health, not only industrial employee, but also society around the company. Exposure of metal industrial waste cause many effects to body’s organs, such as neurology, kidney function, reproduction, hemopoietic, cardiovascular and respiratory system. To solve this problem, many industries have use electrocoagulation-flotation system. Actually, high cost to coagulation and floculan, need high electricity, oxidation effect, depents on electric voltage and also it cannot used for manage high electrolyte fluid. So, many researchers have found other methods for efective metal adsorbent, one of the methods is chitosan. Chitosan has good characteristic to absorp and clot. This compound is used as an absorban heavy metal from industrial waste. Chitosan has amino group and hydroxyl which has high chemical reactivity, and cation polielectrolit to exchange the ion. So, it binds and clots the dangerous metal ion in human’s body. [J Agromed Unila 2014; 1(1):77-81] Key word: chitosan, heavy metal adsorbent, metal industrial waste
Hiperandrogenemia, Hiperinsulinemia, dan Pengaruhnya terhadap Kesuburan pada Policystic Ovary Syndrome Widyastuti Ayu Hardita
Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine Vol. 2 No. 3 (2015): JURNAL AGROMEDICINE
Publisher : Fakultas Kedokteran Universitas Lampung

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Policystic Ovary Syndrome (PCOS) merupakan sindroma disfungsi metabolik dan terdapat kelainan endokrin heterogen pada wanita usia reproduktif. Policystic Ovary Syndrome ditandai oleh terdapatnya hiperandrogenisme, hiperinsulinemia, hipersekresi Luteinizing Hormon (LH), disfungsi menstruasi, hirsutisme, infertilitas, dan komplikasi neonatal dan kehamilan serta ditemukannya ovarium polikistik pada Ultrasonography (USG). Pasien PCOS memiliki kadar Follicle StimulatingHormon (FSH) serum lebih rendah dari orang normal. Defisiensi FSH akan menyebabkan penumpukan folikel kecil yang lebih banyak menyebabkan berhentinya proses pematangan secara dini dan folikel gagal menjadi folikel yang matang. Resistensi insulin diduga memiliki peran penting dalam patofisiologi dengan merangsang produksi androgen ovarium.Ketidaksuburan yang terjadi pada PCOS disebabkan oleh penurunan kualitas oosit akibat produksi hormon androgen yang berlebihan dan resistensi insulin yang mempengaruhi ekspresi dari Glukosa Transporter (GLUT). [J Agromed Unila 2015;2(3):222-225]Kata kunci: FSH, GLUT, hiperandrogenemia, hiperinsulinemia, oosit, PCOS
Cover Agromedicine Admin Agromedicine
Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine Vol. 2 No. 3 (2015): JURNAL AGROMEDICINE
Publisher : Fakultas Kedokteran Universitas Lampung

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Cover Agromedicine
Attention Deficit Hyperactivity Disorder: Diagnosis dan Pendekatan Holistik Suci Widya Primadhani
Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine Vol. 2 No. 3 (2015): JURNAL AGROMEDICINE
Publisher : Fakultas Kedokteran Universitas Lampung

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Attention Deficit Hyperactivity Disorder (ADHD) dikenal dalam bahasa Indonesia dengan sebutan Gangguan Hiperaktif Defisit Perhatian (GHDP). Gangguan ini dikategorikan menjadi 3 tipe yakni inatensi, hiperaktifitas/impulsifitas, dan kombinasi keduanya. Diagnosis terkini ditegakkan melalui kriteria pada Diagnostic and Statistical Manual edisi kelima (DSM-V). Dalam DSM-V kriteria dapat ditegakkan pada anak dan dewasa dengan ADHD. Anak dengan ADHD tentu dapat menjadi masalah bagi perkembangan diri, keluarga dan sosial. Oleh karena itu pendekatan secara holistik diperlukan untuk menghasilkan kualitas hidup yang lebih baik. Pendekatan ini membutuhkan peran serta dari pelayanan pendidikan, sosial (keluarga) dan fasilitas pelayanan kesehatan. Aspek yang diperhatikan dalam memperbaiki kualitas hidup adalah gangguanfungsi dan peran serta anak, kualitas kehidupan, kemampuan beradaptasi, dan kemampuan pengambilan keputusan. Pendekatan secara holistik dengan melakukan pendekatan psikososial dapat dijadikan modalitas terapi disamping terapi medikamentosa. [J Agromed Unila 2015; 2(3):226-231]Kata kunci: ADHD, diagnosis ADHD, DSM-V, pendekatan holistik
Pencegahan dan Tatalaksana HIV/AIDS Muhamad Rizki Prayuda
Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine Vol. 2 No. 3 (2015): JURNAL AGROMEDICINE
Publisher : Fakultas Kedokteran Universitas Lampung

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Acquired Immune Deficiency Syndrome (AIDS) adalah sekumpulan gejala dan infeksi yang timbul karena rusaknya sistem kekebalan tubuh manusia akibat infeksi virus Human Immunodeficiency Virus(HIV).HIV/AIDS merupakan salah satu masalah kesehatan di dunia, khususnya di Indonesia. Jumlah kasus HIV/AIDS terus meningkat dari tahun ke tahun.HIV umumnya ditularkan melalui kontak langsung antara lapisan kulit dalam (membran mukosa) atau aliran darah, dan cairan tubuh yangmengandung HIV. Secara umum, pencegahan atau penanganan HIV/AIDS dibagi menjadi empat kategori, yaitu vaksin, inhibitor entri makromolekular HIV, obat antiretroviral dan terapi berbasis asam nukleat. Beberapa jenis tanaman telah diteliti dalam pengembangan terapi HIV dengan potensi menghambat aktivitas HIV-1 reverse transcriptase. Meskipun penanganan yang telah ada dapat memperlambat laju perkembangan virus, namun penyakit ini belum benar-benar bisadisembuhkan. Pencegahan infeksi HIV adalah dengan mengurangi resiko paparan HIV yang dilakukan dengan beberapa cara.[J Agromed Unila 2015; 2(3):232-236]Kata kunci: AIDS, HIV, pencegahan, penanganan

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