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Alifa S Rahmadhina
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Glosains: Jurnal Sains Global Indonesia
Published by Sekolah Tinggi Agama Islam Kuningan
ISSN : 27984125     EISSN : 27984311     DOI : 10.59784
Core Subject :
Glosains (Jurnal Sains Global Indonesia) is a peer- reviewed scholarly journal managed and published by Sekolah Tinggi Agama Islam Kuningan. The journal serves as an academic platform for researchers, academics, and practitioners in the fields of natural sciences, applied sciences, and interdisciplinary scientific studies. It publishes high-quality original research articles and conceptual papers that contribute to the advancement of scientific knowledge, technological development, and innovative solutions to global and national scientific challenges. Selected articles demonstrate strong scientific rigor, methodological soundness, and originality, providing significant theoretical contributions and practical implications for the scientific community, industry, and society at large.
Arjuna Subject : -
Articles 188 Documents
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Clinical Efficacy of Topical Antioxidants for Skin Photoaging: A Two-Decade Systematic Review Brilian Veda Kartika Putri; Gisela Meydilin Sanjaya; Hany Anneke; Nayla Majeda Alfarafisa; Astrid Feinisa Khairani
Glosains: Jurnal Sains Global Indonesia Vol. 7 No. 3 (2026): Glosains: Jurnal Sains Global Indonesia
Publisher : Sekolah Tinggi Agama Islam Kuningan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59784/glosains.v7i3.831

Abstract

Background: Skin photoaging is driven predominantly by ultraviolet-induced oxidative stress, resulting in wrinkles, pigmentation, loss of elasticity, and skin barrier dysfunction. Topical antioxidants have been proposed as both preventive and corrective interventions; however, the clinical evidence remains fragmented. Objective: This systematic review aimed to evaluate the efficacy and safety of topical antioxidants for the prevention and treatment of skin photoaging. Methods: A systematic search of PubMed, Scopus, ScienceDirect, and the Cochrane Library was conducted through August 2025 following the PRISMA 2020 guidelines. Randomized controlled trials, controlled clinical trials, and prospective interventional studies involving adults with photoaged skin were included. The risk of bias was assessed using RoB 2.0 and ROBINS-I. Of the 1,740 identified records, 23 studies met the eligibility criteria. Results: Vitamin C, vitamin E, ferulic acid, niacinamide, bakuchiol, and plant-derived antioxidants significantly improved wrinkles, pigmentation, skin hydration, and skin elasticity. Combination formulations, particularly vitamin C–vitamin E–ferulic acid serums, demonstrated enhanced efficacy, whereas bakuchiol achieved wrinkle reduction comparable to that of retinol with better tolerability. Topical antioxidants also showed benefits in the management of melasma, postprocedural recovery, and actinic keratosis, with adverse events generally limited to mild, transient irritation. However, heterogeneity in study design, antioxidant formulations, and follow-up duration limited direct comparisons across studies. Conclusion: Topical antioxidants are effective and well-tolerated interventions for skin photoaging, supporting their integration into long-term dermatologic practice. Further large-scale, standardized clinical trials with longer follow-up periods are required to strengthen the evidence.
The IHSAN Model: Integrating the DIKW Framework into Higher Education Curricula for Tawhidic Resilience (An Integrative Review) Ashary Ramdhani; Siti Maryam Munjiat; Pandu Pribadi
Glosains: Jurnal Sains Global Indonesia Vol. 7 No. 3 (2026): Glosains: Jurnal Sains Global Indonesia
Publisher : Sekolah Tinggi Agama Islam Kuningan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59784/glosains.v7i3.833

Abstract

Background: The pervasive secular-modern paradigm in higher education has created a severe epistemological dichotomy between empirical science and religious doctrine, contributing to a crisis of meaning and future anxiety among university students. Objective: This study aims to conceptually develop a novel curriculum architecture that synthesizes modern data hierarchies with Islamic epistemology to cultivate existential resilience. Methods: Employing an integrative literature review approach, this research systematically evaluated multidisciplinary texts across theology, psychology, and educational management utilizing an iterative thematic synthesis to construct a cohesive pedagogical framework. Results: The findings reveal that integrating the data, information, knowledge, and wisdom hierarchy with classical Islamic intellects transforms mechanical learning into profound spiritual wisdom. This integration serves as a robust meaning-making system, generating Tawhidic Resilience, which acts as a divinity-based psychological fortitude. By reframing scientific inquiry as a transcendental spiritual instrument, students develop positive religious coping mechanisms that suggest potential to support the mitigation of psychological distress and moral neuroticism. The discussion highlights the necessity of shifting educators' roles toward spiritual mentorship and emphasizes the implementation of interdisciplinary project-based learning. Conclusion: The study concludes that addressing the psychological vulnerabilities of modern learners requires a holistic curriculum paradigm shift centered on the IHSAN Model and Tawhidic Resilience framework. The proposed model provides a critical theoretical foundation for institutionalizing integrated curricula, enabling Islamic higher education to produce graduates who are both intellectually competent and spiritually resilient.
Financial Management Knowledge, Human Resource Capability, Information Technology Utilization, and Income among Women-Owned MSMEs Reni Dwi Widyastuti; Ali Afif; Sartono Sartono
Glosains: Jurnal Sains Global Indonesia Vol. 7 No. 3 (2026): Glosains: Jurnal Sains Global Indonesia
Publisher : Sekolah Tinggi Agama Islam Kuningan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59784/glosains.v7i3.835

Abstract

Background: Women-owned MSMEs are important to local economic inclusion but may face gaps in financial capability, human resource capability, and digital utilization. Objective: This study aims to analyze the influence of financial management, human resource capability (HR) and information technology on income of Women's MSMEs in Kubu Raya Regency. Methods: The population of this study were women MSMEs in Kubu Raya Regency. The sample of this study amounted to 120 female MSME players, with the technique of collecting sample data using purposive sampling. Data analysis was carried out using multiple regression techniques to test the research hypothesis. This research uses a quantitative approach with SPSS test tools. Results: The results of this study indicate that financial management knowledge, human resource capabilities and utilization of information technology partially and simultaneously have a significant effect on the income of Women's MSMEs in Kubu Raya Regency. Conclusion: Internal capabilities and technology utilization are relevant correlates of the measured income score, but cross-sectional self-reported data do not establish causality.
AI-Assisted Identification of Candidate Diagnostic Biomarkers for Heart Failure Using Multi-Omics Integration Ian Pranandi
Glosains: Jurnal Sains Global Indonesia Vol. 7 No. 3 (2026): Glosains: Jurnal Sains Global Indonesia
Publisher : Sekolah Tinggi Agama Islam Kuningan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59784/glosains.v7i3.843

Abstract

Background: Heart failure (HF) remains a major global health burden associated with high morbidity and mortality. Conventional biomarkers, such as B-type natriuretic peptide (BNP), have limited diagnostic performance because they do not fully capture the molecular complexity of HF. Integrating multi-omics data with artificial intelligence (AI) may improve the identification of novel diagnostic biomarkers. Objective: This study aimed to identify novel diagnostic biomarkers for HF by integrating transcriptomic and proteomic datasets using AI-assisted machine learning. Methods: Public transcriptomic and proteomic datasets from patients with HF and healthy controls were integrated in an in silico bioinformatics study. Differential expression analysis was performed to identify dysregulated genes and proteins, followed by Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment, and protein–protein interaction (PPI) network analyses. Candidate biomarkers were prioritized using Least Absolute Shrinkage and Selection Operator (LASSO), Random Forest, and Extreme Gradient Boosting (XGBoost). Diagnostic performance was evaluated using receiver operating characteristic (ROC) curve analysis. Results: Multi-omics integration identified 1,247 differentially expressed genes, 186 differentially expressed proteins, and 42 overlapping molecules. Enrichment analyses indicated significant involvement in cardiac remodeling, inflammation, oxidative stress, energy metabolism, and calcium signaling. Five hub biomarkers (NPPB, ATP2A2, IL6, PPARGC1A, and TGFB1) were consistently selected by all machine learning models. Individual biomarkers achieved area under the ROC curve (AUC) values ranging from 0.88 to 0.94, whereas the combined five-biomarker panel achieved an AUC of 0.97, with 92.4% sensitivity and 90.1% specificity. Conclusion: AI-assisted multi-omics integration identified five biologically relevant biomarkers with excellent diagnostic performance, providing a promising foundation for future HF diagnostics and precision cardiology.
Content Validity of the Indonesian Version of the Carpal Tunnel Syndrome-6 (CTS-6) for the Assessment of Carpal Tunnel Syndrome Jesisca Jesisca; Sekplin A. S. Sekeon; Seilly Y. Jehosua; Herlyani Khosama; Denny J. Ngantung
Glosains: Jurnal Sains Global Indonesia Vol. 7 No. 3 (2026): Glosains: Jurnal Sains Global Indonesia
Publisher : Sekolah Tinggi Agama Islam Kuningan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59784/glosains.v7i3.844

Abstract

Background: The Carpal Tunnel Syndrome-6 (CTS-6) is a brief clinical scoring instrument used to assess the primary symptoms and signs of carpal tunnel syndrome (CTS). Before being used in Bahasa Indonesia, the instrument must undergo linguistic adaptation and content validity assessment to ensure that each item remains relevant and consistent with the clinical construct being measured. Objective: To develop the Indonesian version of the CTS-6 and evaluate its content validity. Methods: The adaptation process was conducted through forward translation, translation synthesis, expert content validity assessment, pretesting and discussion, backward translation, and finalization. Content validity was assessed by three neurologists using the Content Validity Index (CVI) with a 4-point relevance scale. Results: All six CTS-6 items received relevance ratings of 3 or 4 from all three experts. The Item-Level Content Validity Index (I-CVI) for all items was 1.00, while both the Scale-Level Content Validity Index based on the Average method (S-CVI/Ave) and the Scale-Level Content Validity Index based on Universal Agreement (S-CVI/UA) were 1.00. Editorial and operational revisions were made without altering the core concept of any item. Conclusion: The Indonesian version of the CTS-6 demonstrated excellent content validity and may serve as a foundation for the use of a concise clinical scoring instrument for assessing carpal tunnel syndrome. Further studies are needed to evaluate its reliability and other psychometric properties.
Collaborative Governance in Optimizing State Revenue through Customs Facilities in the Sanur Special Economic Zone Ah Farid Nurrohman; Luh Putu Mahyuni
Glosains: Jurnal Sains Global Indonesia Vol. 7 No. 3 (2026): Glosains: Jurnal Sains Global Indonesia
Publisher : Sekolah Tinggi Agama Islam Kuningan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59784/glosains.v7i3.852

Abstract

Background: The Sanur Special Economic Zone (SEZ) is a strategic government initiative that integrates health services, tourism, and investment activities. The provision of customs facilities in SEZs provides investment incentives but also creates potential fiscal risks that require accountable governance and effective supervision. Therefore, collaborative governance is essential to ensure that fiscal facilities support economic growth while maintaining state revenue protection. Objective: This study aims to analyze collaborative governance practices in managing customs facilities at the Sanur SEZ and identify factors influencing the optimization of potential state revenue. Methods: This study employed a qualitative case study approach. Data were collected through document analysis, micro-evaluation reports of Sanur SEZ, performance evaluation reports, special monitoring reports, focus group discussions, interviews, and regulatory reviews. Data were analyzed using Ansell and Gash’s collaborative governance framework, focusing on dialogue, trust building, commitment, shared understanding, and intermediate outcomes. Results: The findings indicate that customs facilities function as both investment incentives and fiscal supervision instruments. Collaboration among government institutions, SEZ administrators, and business actors has contributed to increased investment, employment, facility utilization, and monitoring effectiveness. However, challenges remain in system integration, IT Inventory implementation, regulatory consistency, and compliance. Special monitoring identified potential revenue recovery through import duty and tax collection recommendations totaling IDR 813,129,741. Conclusion: Strengthening collaborative governance through digital integration, transparency, and continuous evaluation is crucial to optimizing state revenue while maintaining investment competitiveness in the Sanur SEZ.
Digital Javanese Script Literacy for Cultural Tourism Communication Yenni Sri Utami; Ida Wiendijarti; Oliver Samuel Simanjuntak
Glosains: Jurnal Sains Global Indonesia Vol. 7 No. 3 (2026): Glosains: Jurnal Sains Global Indonesia
Publisher : Sekolah Tinggi Agama Islam Kuningan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59784/glosains.v7i3.853

Abstract

Background: Bantul Regency promotes cultural tourism through the "Bantul Bumi Mataram" branding, which positions Mataram heritage, including the Javanese script (Hanacaraka), as a core destination asset. However, most tourism actors in Bantul have limited literacy in Javanese script, restricting their ability to explain cultural symbols to visitors and reducing the effectiveness of this branding strategy. Objective: This study develops and evaluates an Android-based digital literacy model for Javanese script that improves tourism actors’ script literacy and strengthens cultural tourism promotion in Bantul Regency. Methods: This research and development (R&D) study combined a needs analysis with a prototyping approach, using interviews, observation, and questionnaires administered to a purposive sample of tourism actors [author to confirm exact sample size] in Bantul Regency. The application was built with Adobe Flash Professional CS6 and evaluated through limited user trials with pre-test/post-test measurement of script-reading accuracy [author to confirm test scores]. Results: Tourism actors initially recognized only basic Hanacaraka characters and could not read simple sentences. After using the application, participants showed improved script-reading accuracy in the post-test [author to insert percentage/effect size] and reported greater confidence in explaining Javanese cultural symbols to visitors. Conclusion: The Android-based digital literacy model strengthens tourism actors’ Javanese script competence and reinforces Bantul’s cultural identity within the Bantul Bumi Mataram branding strategy, offering a replicable approach for digitally preserving other endangered scripts.
Technical and Relational Drivers of Loyalty and Switching Intention among B2B Customers Irfan Chairudin; Ahmad Ikhwan Setiawan
Glosains: Jurnal Sains Global Indonesia Vol. 7 No. 3 (2026): Glosains: Jurnal Sains Global Indonesia
Publisher : Sekolah Tinggi Agama Islam Kuningan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59784/glosains.v7i3.869

Abstract

Background: The automotive refinishing industry is an important part of the automotive aftermarket ecosystem that relies on long-term relationships between suppliers and business-to-business (B2B) customers. In an increasingly competitive environment, understanding the factors influencing customer satisfaction, customer loyalty, and switching intention is essential to support business sustainability. Objective: This study aims to examine the effects of product quality, technical service quality, brand image, relationship marketing, and product availability on customer satisfaction, customer loyalty, and switching intention, as well as to investigate the moderating role of perceived switching cost. Methods: This study employed a quantitative explanatory approach involving 196 B2B customers in the automotive refinishing industry in Indonesia. Data were collected through a structured questionnaire survey and analyzed using Partial Least Squares Structural Equation Modeling (PLS-SEM). Results: The findings indicate that product quality, technical service quality, brand image, relationship marketing, and product availability positively affect customer satisfaction. Relationship marketing and product availability also have positive effects on customer loyalty. Customer satisfaction significantly increases customer loyalty and reduces switching intention, while customer loyalty negatively affects switching intention. Furthermore, perceived switching cost strengthens the effects of customer satisfaction and customer loyalty in reducing switching intention. Conclusion: Customer loyalty in the automotive refinishing industry is influenced by a combination of technical and relational factors. Companies should enhance product quality, technical services, product availability, brand image, and customer relationships to improve customer satisfaction and loyalty while reducing customers’ propensity to switch to alternative suppliers.

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