International Journal of Integrated Health Sciences
International Journal of Integrated Health Sciences (IJIHS) is a peer-review journal which publishes original articles, medical research, clinical research and case report. This journal is supported by Faculty of Medicine Universitas Padjadjaran and was launched on September 22nd 2012 and firstly published on July 2013. The first and second publications in 2013 and 2014 were published annually. In 2015 IJIHS published twice in a year, March and September.
Articles
187 Documents
<![CDATA[Antibiotic Utilization Pattern in the Intensive Care Unit of Tertiary Hospital in West Java, Indonesia ]]>
<![CDATA[Taradharani Wikantiananda]]>;
<![CDATA[Adi Imam Tjahjadi]]>;
<![CDATA[Reza Widianto Sudjud]]>
<![CDATA[ International Journal of Integrated Health Sciences Vol 7, No 2 (2019) ]]>
Publisher : <![CDATA[Faculty of Medicine Universitas Padjadjaran ]]>
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DOI: 10.15850/ijihs.v7n2.1633
<![CDATA[Objective: To find out the pattern of antibiotic utilization in intensive care unit (ICU). The high use of antibiotics in intensive care may increase antibiotic resistance.Methods: This was a retrospective study with total sampling method from patients who were treated in ICU in the period of January to June 2016. Selected data is processed using the Anatomical Therapeutic Chemical (ATC) Classification/Defined Daily Dose (DDD) system as an international measurement standard for analyzing and comparing usage applied by the WHO.Results: The results showed that of the 57 medical records collected, the total antibiotic use was 295.72 DDD/100 bed-days. Levofloxacin, meropenem, ceftriaxone, ceftazidime, and metronidazole were the five maximally utilized antibiotics with 143.18, 49.88, 30.62, 19.74, dan 16.99 DDD/100 bed-days respectively.Conclusion: The most frequently used of antibiotics is ceftriaxone, used in 54.39% of patients. Whereas in number, the most widely used antibiotic is levofloxacin with a total of 143.18 DDD/100 bed-days.]]>
<![CDATA[Relationship between the Quality of Informed Consent at Surgical Procedure in Terms of Ethics and Medicolegal with Satisfaction of Patient Health Service in dr. Zainoel Abidin Hospital ]]>
<![CDATA[Taufik Suryadi Ismail]]>;
<![CDATA[Putra Safana]]>;
<![CDATA[Dedy Syahrizal]]>
<![CDATA[ International Journal of Integrated Health Sciences Vol 8, No 1 (2020) ]]>
Publisher : <![CDATA[Faculty of Medicine Universitas Padjadjaran ]]>
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DOI: 10.15850/ijihs.v8n1.2000
<![CDATA[Objective: To determine the relationship between the quality of informed consent in terms of ethics and medicolegal with patient health service satisfaction at the dr. Zainoel Abidin Hospital (ZAH) Banda Aceh.Method: This study is an observational analytic with a cross-sectional method. Subject selection through a total sampling method. This study involved patients who were treated at dr. Zainoel Abidin Hospital (ZAH) Banda Aceh and a total of patients were 100 (52 men and 48 women) who met the inclusion criteria carried out on 16 December 2019 to 31 December 2019.Results: As many as 90% of respondents rated informed consent made at ZAH as good quality and 85% expressed the satisfaction with health services at ZAH. An ethical and medicolegal review of informed consent emphasizes the basic principles of bioethics. As many as 84% of respondents stated that their autonomy rights had been fulfilled, 92.50% thought that the doctor had done beneficence, nonmaleficence, and justice well in the process of informed consent and 92.33% of respondents rated the three elements of informed consent as being well implemented. Based on the results of the chi-square statistical test showed a significant relationship between the quality of informed consent in terms of ethics and medicolegal with patient health service satisfaction under the value of p = 0.001 (p≤0.05).Conclusion: Good quality of informed consent in terms of ethics and medicolegal has an important role in increasing patient satisfaction with health services at the dr. Zainoel Abidin Hospital of Banda Aceh.]]>
<![CDATA[Comparison of Cognitive Functions between Paroxysmal and Persistent Atrial Fibrillation Patients without Clinical Stroke ]]>
<![CDATA[Caepy Gomer]]>;
<![CDATA[Paulus Anam Ong]]>;
<![CDATA[Sobaryati Sobaryati]]>;
<![CDATA[Badai Bhatara Tiksnadi]]>
<![CDATA[ International Journal of Integrated Health Sciences Vol 8, No 1 (2020) ]]>
Publisher : <![CDATA[Faculty of Medicine Universitas Padjadjaran ]]>
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DOI: 10.15850/ijihs.v8n1.1974
<![CDATA[Objective: To compare cognitive functions between paroxysmal and persistent atrial fibrillation patients without clinical stroke, in terms of MoCA-Ina total score and MoCA-Ina cognitive subdomains scores. Methods: A comparative study that compared MoCA-Ina scores between paroxysmal and persistent AF patients without clinical stroke, who came for treatment at the Cardiology Clinic Dr. Hasan Sadikin General Hospital, Bandung and Dustira Hospital, Cimahi from September 2018–January 2019. Results: Sixty four subjects were recruited, consisted of 24 paroxysmal and 40 persistent AF patients. There were no difference in clinical characteristics between two groups, except that there were more subjects in the persistent AF group using anticoagulants therapy: 97.5% vs 62.5% (p=0.005) and more prevalence of type 2 Diabetes Mellitus in the paroxysmal AF group: 25% vs 2.5% (p=0.009). Cognitive impairment (MoCA-Ina score <25) were seen in 70.8% of paroxysmal AF group and 82.5% of persistent AF group (p=0.274). The mean MoCA-Ina total score in the paroxysmal and persistent AF groups were 21.04±4.75 vs 20.70±4.21 (p=0.989), respectively. The median MoCA-Ina cognitive subdomains scores were similar for the two groups (p>0.05).Conclusion: There were no differences in cognitive functions between paroxysmal and persistent AF patients, both in terms of MoCA-Ina total score and MoCA-Ina cognitive subdomains scores, although in both groups had cognitive decline.]]>
<![CDATA[High Tissue Factor Microparticle Level in Major Thalassemic Patients with Pulmonary Hypertension ]]>
<![CDATA[Dimmy Prasetya]]>;
<![CDATA[Pandji Irani Fianza]]>;
<![CDATA[Erwan Martanto]]>;
<![CDATA[Teddy Arnold Sihite]]>
<![CDATA[ International Journal of Integrated Health Sciences Vol 7, No 2 (2019) ]]>
Publisher : <![CDATA[Faculty of Medicine Universitas Padjadjaran ]]>
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DOI: 10.15850/ijihs.v7n2.1658
<![CDATA[Objective: To analyze the correlation between tissue factor microparticles (TF-MP) levels and pulmonary hypertension (PH) in adult thalassemic patients. Methods: This study was conducted from September to October 2018, using secondary and primary data. The secondary data consisted of the PH parameter, which was retrieved from a 2017 previous study entitled ‘Clinical Characteristic and Complication due to Iron Overload in Thalassaemic Patients‘in 2017 while the primary data were the TF-MP, which were obtained from the analysis of frozen serum of the same population using ELISA method. The mean pulmonary arterial pressure (mPAP) values were obtained from echocardiography results and PH was defined as mPAP >25 mmHg.Results: Seven (16.7%) major thalassemic patients experienced PH. The median values of TF-MP levels were higher among major thalassemic patients with PH when compared to the non-PH patients (1569 vs 11.5 pg/dL; p=0.023). No significant difference was observed in the median TF-MP levels between subjects with splenectomy and subjects without splenectomy (11.6 vs 12.3 pg/dL; p=0.44). There was also no difference in mPAP values between subjects with splenectomy and subjects without splenectomy (18.0 vs 17.0 mmHg; p=0.663). When the median TF-MP levels among major thalassemic patients were analyzed in terms of correlation with transfusion level, no statistically significant difference was seen between subjects who received sufficient transfusions (≥180 mL/kgbb/year) and those who received insufficient transfusions (<180 mL/kgbb/year) (r= 0.138; p=0.390).Conclusions: There is a positive correlation between the TF-MP levels and PH in adult major thalassemic subjects.]]>
<![CDATA[Venous Thromboembolism Prophylaxis and The International Medical Prevention Registry on Venous Thromboembolism (IMPROVE) Score in Medical Illness Patients ]]>
<![CDATA[Dania Artriana Riswandi]]>;
<![CDATA[Amaylia Oehadian]]>
<![CDATA[ International Journal of Integrated Health Sciences Vol 8, No 1 (2020) ]]>
Publisher : <![CDATA[Faculty of Medicine Universitas Padjadjaran ]]>
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DOI: 10.15850/ijihs.v8n1.1773
<![CDATA[Objective: To describe applicability of The International Medical Prevention Registry on Venous Thromboembolism (IMPROVE) score to implement venous thromboembolism prophylaxis in patients with medical illness in Hasan Sadikin General Hospital Bandung.Methods: This study was descriptive, cross-sectional research from database was performed on December 2018. Inclusion criteria in this study were all patients hospitalized in Department of Internal Medicine, Hasan Sadikin General Hospital in November 2018 with medical illness, which is patients with medical condition involves a more systemic, pharmaceutical approach to treatment. Exclusion criteria were surgical disease, which is requires some form of intervention such as surgery, also patients with incomplete medical record were excluded.Results: There were 162 patients (56% male and 44% female). Median age were higher in males compared to females (53 [18-76] vs. 49 [18-85]) years. Low-risk (score <2), medium-risk (score 2 – 3), and high-risk (score >4) for IMPROVE venous thromboembolism score were 77.2%, 17.3%, and 5.6% respectively. ). Low-risk (score <7) and high-risk (score >7) for IMPROVE bleeding score were 75.9% and 24.1% respectively. Medical thromboprophylaxis were given to 14.8% patients, with 91.7% and 8.3% of the patients received unfractionated heparin (UFH) and low-molecular weight heparin (LMWH) respectively. Thromboprophylaxis was given in 88.9% of high-risk patients for venous thromboembolism. There were 18.7% patients with low-risk and 2.6% with high-risk for bleeding that received prophylaxis.Conclusion: The majority of inpatients treated with thromboprophylaxis had low-risk for both thromboembolism and bleeding. The rate of thromboprophylaxis usage was still low; with the most frequently used thromboprophylaxis agent was UFH. Most of high-risk patients for venous thromboembolism received thromboprophylaxis. ]]>
<![CDATA[Clinical Manifestations and Hematological Profiles of Pediatric Acute Myeloblastic Leukemia Patients: 3 Years Observational Study in A West Java Tertiary Hospital, Indonesia ]]>
<![CDATA[Agustinus Wiraatmadja]]>;
<![CDATA[Nur Suryawan Hidayat]]>;
<![CDATA[Adhi Kristianto Sugianli]]>
<![CDATA[ International Journal of Integrated Health Sciences Vol 7, No 2 (2019) ]]>
Publisher : <![CDATA[Faculty of Medicine Universitas Padjadjaran ]]>
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DOI: 10.15850/ijihs.v7n2.1480
<![CDATA[Objective: To determine and describe the clinical manifestations and hematological profiles of pediatric Acute Myeloblastic Leukemia (AML) in Dr. Hasan Sadikin General Hospital (RSHS), Bandung as a tertiary hospital in West Java, Indonesia.Methods: A retrospective cross-sectional study using the total sampling method was performed on the medical records of pediatric patients (0-18 years old)who were diagnosed as AML for the first time through bone marrow examination during the period of January 1, 2015 – December 31, 2017. Results: Of the 54 subjects who met the inclusion criteria, 42.6% were AML patients in the age group 6-12 years with male patients comprised 59.3% of the total number of subjects. Patients generally experienced pallor (83.3%), fever (75.9%), and decreased appetite (70.4%). The hematological profiles showed that 35.2% of patients had Hb <6.5 g/dL and 44.4% had a leukocyte count of of >50,000 cells/mm3. The majority of the subjects had a platelet count of <50,000 cells/mm3 (83.3%) and almost half of them had a peripheral blasts count of >50% (46.3%). Conclusion: Clinical manifestations and hematological profiles are important to diagnose AML, especially in pediatric patients. By assessing the manifestations and profiles, it is feasible to access and detect suspected cases of AML.]]>
<![CDATA[Serum Albumin Levels of Oral Candidiasis Immunosuppressed Rats Treated With Hyperbaric Oxygen ]]>
<![CDATA[Pargaputri, Agni Febrina]]>;
<![CDATA[Andriani, Dwi]]>
<![CDATA[ International Journal of Integrated Health Sciences Vol 8, No 1 (2020) ]]>
Publisher : <![CDATA[International Journal of Integrated Health Sciences ]]>
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DOI: 10.15850/ijihs.v8n1.2086
<![CDATA[Objective: To investigate serum albumin levels in oral candidiasis immunosuppressed rats treated with hyperbaric oxygen. One of the predisposing factors for oral candidiasis was the use of immunosuppressive drugs continuously. It can also affect the work of the liver because it’s one of the organs responsible for drug metabolism. Hyperbaric oxygen therapy was used not only to suppressing fungal infections, but also to improve liver function by evaluating the serum albumin levels.Methods: This study used a post-test only control group design. Fifteen Wistar rats were divided into 3 groups(n=5/3): G1 (healthy group), G2 (oral candidiasis immunosuppressed rats group without hyperbaric oxygen therapy), and G3 (oral candidiasis immunosuppressed rats group with hyperbaric oxygen therapy). G2 and G3 groups were immunosuppressed by giving dexamethasone 0,5mg/day/rat orally for 14 days, added with tetracycline 1 mg/day/rat. Hyperbaric oxygen therapy was given to the G3 group in 5 days. Blood serum of rats in all groups was taken to calculate albumin levels.Results: The average value of albumin levels in G2 group showed a decrease compared to the G1 group, while G3 showed the highest level. One way Anova test showed a significant difference among groups (p<0,05). To compare the difference between each group we used LSD test and showed a significant difference (p<0,05) between G1 compared to G2, G1 compared to G3, and G2 compared to G3.Conclusion: Liver albumin levels of oral candidiasis immunosuppressed rats treated with hyperbaric oxygen therapy showed higher levels than those without therapy.]]>
<![CDATA[Post-Lumbar Puncture Chronic Intracranial Subdural Hematoma ]]>
<![CDATA[Mathew, Sherman David]]>;
<![CDATA[Abraham, Betsy]]>
<![CDATA[ International Journal of Integrated Health Sciences Vol 7, No 2 (2019) ]]>
Publisher : <![CDATA[Faculty of Medicine Universitas Padjadjaran ]]>
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DOI: 10.15850/ijihs.v7n2.1679
<![CDATA[Objective: To desribe a case of cranial subdural hematoma as an atypically sporadic and potentially devastating complication of a lumbar puncture mimicking post-dural puncture headache which may lead to delayed diagnosis.Method: This is a a case report of chronic intracranial subdural hematoma as a complication of lumbar puncture for spinal anaesthesia in a forty-eight-year-old male underwent an uneventful ureterolithotomy. In the postoperative period, the patient complained of excruciating headache which partially subsided with symptomatic treatment. However, after four weeks, the patient presented with worsening headache and  vomiting.Results: A contrast enhanced computer tomography study revealed a subdural haematoma in the left fronto-temporo-parietal-region. The patient underwent an immediate decompressive craniectomy for subdural hematoma. The postoperative period was  uneventful and the patient was discharged without any neurological deficits.Conclusion: Intracranial complication such as subdural hematoma is rare after a dural puncture and is often masquerading as a post dural puncture headache. Imaging studies like computerized tomography and magnetic resonance imaging are to be considered in earlier stages of non-retractable headache to rule out such rare complications.]]>
<![CDATA[Intracranial Metastasis as the Initial Presentation of a Young Woman with Luminal B Her-2 Positive Stage 4 Breast Cancer ]]>
<![CDATA[Gultom, Santi Christiani]]>;
<![CDATA[Oehadian, Amaylia]]>
<![CDATA[ International Journal of Integrated Health Sciences Vol 8, No 1 (2020) ]]>
Publisher : <![CDATA[Faculty of Medicine Universitas Padjadjaran ]]>
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DOI: 10.15850/ijihs.v8n1.1886
<![CDATA[Objective: Breast cancer is the second most common cause of brain metastasis (BM) among all of the solid cancers, with metastases occurring in 10%–16% of patients and in as many as 30% of autopsy studies. Breast cancer-related BM usually has a poor prognosis and survival rate in the absence of any treatment within 2 months. Survival after BM is related to the subtype of the primary tumor. Human epidermal growth factor-2 (HER-2)-positive patients have a significantly better prognosis compared with other subtypes. The prognosis for the majority of patients with BM remains poor, despite local and systemic therapies, with a median survival of around 10 months.Methods: This case is interesting because our patient is very young, diagnosed with BM before breast cancer was identified, bit still surviving 12 months after her BM diagnosis. A 19-year old woman presented with seizures, vomit and headaches.Results: A cranial CT-scan showed an intracranial mass. The intracranial tumor was removed, and yielded a histopathological result of metastatic adenocarcinoma. Further examination found a lump in her right breast. She was diagnosed with intracranial metastatic stage 4 luminal B Her 2(+) breast cancer. She was referred for WBRT, a mastectomy, chemotherapy with docetaxel cyclophosphamide 4 cycles, followed by 12 cycles of trastuzumab, and continued treatment with tamoxifen and goserelin. The last PET-Scan showed no residual disease.Conclusion: Breast cancer as the primary tumor should be considered in women with a metastatic brain tumor. With appropriate treatment, even stage IV luminal B breast cancer with BM can still have a long life with good quality.]]>
<![CDATA[Antibiotic Use Pattern in Orthopaedics and Traumatology Ward: A 6 Month Survey in A Tertiary Hospital ]]>
<![CDATA[Ethelie, Stanislaus Gerald]]>;
<![CDATA[Tjahjadi, Adi Imam]]>;
<![CDATA[Primadhi, Andri]]>
<![CDATA[ International Journal of Integrated Health Sciences Vol 7, No 2 (2019) ]]>
Publisher : <![CDATA[International Journal of Integrated Health Sciences ]]>
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DOI: 10.15850/ijihs.v7n2.1522
<![CDATA[Objective: To determine and describe the antibiotic use pattern in the orthopedics and traumatology ward of Dr. Hasan Sadikin General Hospital Bandung as a tertiary hospital in West Java, Indonesia.Methods: A retrospective cross-sectional study using the total sampling method was performed on the medical records of orthopedics and traumatology patients treated using antibiotics during the period of January 1, 2016 and June 31, 2016.Results: From the 261 subjects who met the inclusion criteria, it was discovered that the most common antibiotics used were in the following order: cefazolin (54.41%), ceftriaxone (21.84%), and cefotaxime (10.35%). Most antibiotics (75.86%) were given as prophylaxis. Antibiotics were most often administered for 2-3 days (42.53%), intravenously (97.7%), and with a dose of 2x1 gram (92.16%).Conclusion: The most frequently used antibiotics in the orthoaedics and traumatology ward of Dr. Hasan Sadikin General Hospital (RSHS) was cefazolin, which was mostly used as a pre-surgical antibiotic. The use of third-generation cephalosporin antibiotics as pre-surgical antibiotics is still observed during this study. ]]>
