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Medula
Published by Universitas Lampung
ISSN : -     EISSN : 97726154     DOI : -
Core Subject : Health, Science, Education,
Education Medicine & Pharmacology Neuroscience Public Health
Medical Profession Journal of Lampung didirkan pada tahun 2013. Medula hadir memenuhi kebutuhan publikasi jurnal bagi mahasiswa Fakultas Kedokteran, Dosen ataupun klinisi dan profesi lain dibidang kedokteran. Medula diterbitkan dengan frekuensi 4 kali dalam setahun yang tiap nomornya mencakup 30 jenis artikel ilmiah seperti artikel penelitian, laporan kasus, tinjauan pustaka dan lain-lain. Medula sudah memiliki nomor ISSN media cetak sejak tahun 2013
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 12 Documents
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Search results for , issue "Vol 16 No 3 (2026): Medula" : 12 Documents clear
Perbandingan Absolute Lymphocyte Count (ALC) Antara Pasien Terkonfirmasi Dengan Probable Covid 19 Di RSUD Pesawaran Kurniawan, Denny Andika; Utama, Winda Trijayanthi
Medula Vol 16 No 3 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v16i3.1763

Abstract

Coronavirus Disease 2019 (COVID-19) is a broad group of viruses known to cause diseases with a diverse clinical spectrum, ranging from mild symptoms to severe disorders in humans. These viruses are zoonotic, meaning they can be transmitted from animals to humans, posing a major challenge in infection control efforts. In addition, variations in immune responses in each individual cause the clinical picture of Covid-19 to vary greatly, including changes in laboratory parameters such as absolute lymphocyte count (ALC). This study was conducted to analyze the differences in ALC values in patients with a confirmed diagnosis of Covid-19 compared to patients categorized as probable Covid-19 at the Pesawaran Regional General Hospital. The study design used an observational analytical method with a cross-sectional approach. Data processing and analysis were performed using an independent t-test to assess the difference in means between the two groups. The total sample consisted of 45 patients, namely 20 patients with confirmed Covid-19 and 25 patients with probable Covid-19. The results showed that the mean ALC value in the confirmed group was 1,241.5/µL, while in the probable group it reached 1,812.59/µL. These findings indicate a statistically significant difference between the mean ALC of the two groups, with a p-value of 0.0001. This difference also supports the findings of previous studies that lymphopenia is more commonly found in patients with verified Covid-19 infection. Thus, this study confirms that Covid-19 confirmation status is associated with changes in ALC, which can be a supporting clinical parameter in the evaluation and monitoring of patient conditions.
Perbandingan, Monoterapi, Double Terapi, Triple Kombinasi Terapi Pada Pasien Glaukoma Primer Sudut Terbuka Di Rumah Sakit Mata Lampung Eye Center Zaiva, Syalsa; Karima, Nisa
Medula Vol 16 No 3 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v16i3.1764

Abstract

The eye is an essential sensory organ that delivers visual information to the brain. Glaucoma is a progressive optic neuropathy that can disrupt this process and lead to irreversible blindness. Primary open angle glaucoma is the most common type and is characterized by a gradual increase in intraocular pressure with minimal early symptoms. Glaucoma treatment is usually initiated with single drug therapy or monotherapy. If monotherapy is insufficient to control intraocular pressure, combination therapy using two or more medications is required, including double therapy and triple combination therapy. This study aimed to compare the effectiveness of monotherapy, double therapy, and triple combination therapy in reducing intraocular pressure in patients with primary open angle glaucoma at Lampung Eye Center Eye Hospital. An observational analytic method with a cross sectional design was used. Data on intraocular pressure and treatment regimens were obtained from medical records. Bivariate analysis was performed using the Kruskal Wallis test. The results showed that most subjects were male, with 23 patients or 53.5%, and the most common age group was 40 to 60 years, accounting for 41.9% of participants. Of the 43 patients included, 20.9% (9 patients) received monotherapy, 60.5% (26 patients) received double therapy, and 8 patients or 18.6% received triple combination therapy. Bivariate analysis demonstrated a statistically significant reduction in intraocular pressure in patients receiving triple combination therapy, with a p value less than 0.05. These findings indicate that triple combination therapy provides the most significant intraocular pressure reduction in patients with primary open angle glaucoma.
Mosquito Control Methods and Dengue Fever Disease: a Literature Review Khairunnisa, Aulia; Graharti, Risti
Medula Vol 16 No 3 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v16i3.1772

Abstract

Dengue Hemorrhagic Fever (DHF) is one of the vector-borne diseases that remains a public health challenge in Indonesia, characterized by high incidence rates, widespread vector distribution, and an increased risk of outbreaks in various endemic areas. The transmission of the dengue virus is greatly influenced by community behavior, residential environmental conditions, and the bioecology of the Aedes aegypti mosquito, which is able to breed in clean water puddles around homes. The dengue virus consists of four serotypes and can survive through vertical and horizontal transmission mechanisms, thereby strengthening the chain of transmission in the environment. On the other hand, vector control efforts using larvicides and chemical insecticides are still widely chosen by the community, even though improper use can cause insecticide resistance. This study aims to examine various methods of dengue vector control, including physical, mechanical, biological, chemical approaches, and the EcoHealth concept. The method used was a literature review of official guidelines, research articles, and the latest scientific publications on DHF and vector control. The results of the study show that physical control methods such as 3M Plus are the most effective and safest, while biological control through larval predators and environmentally friendly bacteria can reduce the larval population without causing negative ecological impacts. Chemical control still provides rapid effects, but must be used wisely to prevent resistance. The EcoHealth approach is considered more comprehensive because it involves environmental, social, cultural, and economic aspects of the community in sustainable control. In conclusion, optimal DHF control requires an evidence-based integrated strategy with cross-sector participation and the application of ecological principles to ensure long-term success in reducing disease incidence.
Evaluasi kadar CRP High Sensitivity sebagai Marker Risiko Kardiovaskular pada Dewasa Muda: Indonesia Rachmantiawan, Aldiano; Sangging, Putu Ristyaning Ayu
Medula Vol 16 No 3 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v16i3.1773

Abstract

Atherosclerosis and cardiovascular disease originate from chronic low grade inflammatory processes, making high sensitivity C reactive protein or hs CRP widely studied as a cardiovascular risk marker, including in young adults. This study is a narrative review of 16 articles published between 2019 and 2025 that examine hs CRP in young adults aged 18 to 45 years and its association with cardiometabolic risk factors, cardiovascular disease events, and clinical outcomes. The review findings indicate that in overweight or obese young adults, elevated hs CRP levels are associated with central obesity, atherogenic dyslipidemia, impaired fasting glucose, and higher blood pressure. In addition, irregular sleep patterns and short term variability in diastolic blood pressure are also linked to increased hs CRP levels, suggesting the presence of subclinical inflammation early in life. In older populations and in patients with established cardiovascular disease, high hs CRP levels are reported to predict cardiovascular disease incidence, carotid plaque formation, cardiometabolic multimorbidity, functional disability, and short term mortality. However, hs CRP is not associated with the progression of coronary artery calcification and demonstrates substantial intra individual variability. Overall, hs CRP has potential value as an additional marker to identify young adults at higher cardiovascular risk. Nevertheless, hs CRP is not sufficient as a single screening tool and should be interpreted alongside traditional cardiovascular risk factors and lifestyle patterns. Repeated measurements are recommended to improve risk assessment accuracy and to account for biological variability in hs CRP levels.
Laporan Kasus: Seorang Laki-Laki Usia 48 Tahun dengan Herniasi Nukleus Pulposus Servikal Fakhrizal, Muhammad Alka; Ramadhian, Muhammad Ricky; Wicaksono, Danang Samudro; Afrida, Frecilia; Ananda, Yovani Tria
Medula Vol 16 No 3 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v16i3.1801

Abstract

Cervical herniated nucleus pulposus is a common cause of neck pain, radicular pain, and neurological deficits resulting from compression of cervical nerve roots by intervertebral disc pathology. The incidence of cervical radiculopathy peaks in the fourth and fifth decades of life and is closely associated with degenerative disc changes. This report presents the case of a 48 year old male who complained of chronic neck pain radiating to the upper back and right upper extremity, accompanied by paresthesia, restricted cervical range of motion, and weakness during right arm elevation. The symptoms had persisted for one year and progressively worsened over the last two months, with no history of trauma. The patient also reported intermittent burning sensations that improved with rest. These clinical features were consistent with cervical radiculopathy caused by progressive cervical disc herniation. Magnetic resonance imaging of the cervical spine in sagittal sections revealed disc protrusion at the C5 C6 level causing anterior spinal canal compression, as well as mild disc protrusion at C6 C7 with narrowing of the anterior subarachnoid space. Thoracic spine MRI showed no significant abnormalities. Initial management consisted of conservative therapy using non steroidal anti inflammatory drugs and gabapentin to address inflammatory and neuropathic pain components. Due to persistent symptoms and motor weakness, surgical intervention with percutaneous endoscopic cervical discectomy was planned. A thorough understanding of cervical spine anatomy, disc herniation pathophysiology, clinical manifestations, and imaging findings is essential for accurate diagnosis and appropriate treatment selection to prevent symptom progression and deterioration of patient quality of life.
Perbedaan Tingkat Pengetahuan Tentang Diabetes Melitus Dengan Kadar Gula Darah Sewaktu Pasien DM Tipe 2 Saribu, Samintola Dolok; Utama, Winda Trijayanthi
Medula Vol 16 No 3 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v16i3.1806

Abstract

Diabetes mellitus (DM) is a degenerative disease characterized by elevated blood sugar levels or hyperglycemia. The incidence of DM continues to increase every year, influenced by various factors such as suboptimal recovery, the need for continuous consumption of antidiabetic drugs, uncontrolled blood sugar levels, and low patient knowledge about the disease. This condition can worsen complications and reduce the quality of life of patients. This study was conducted to determine the difference in the level of knowledge about diabetes mellitus with blood sugar levels in type 2 diabetes mellitus patients at Dr. H. Abdul Moeloek Regional General Hospital in Lampung Province. This study used a descriptive method with a cross-sectional study design. Sampling was conducted using non-probability sampling, specifically consecutive sampling, with instruments in the form of questionnaires to measure knowledge levels and random blood sugar level tests. Data were analyzed using the chi-square test to see the relationship between variables. A total of 35 respondents participated in this study, with 11.4% in the good knowledge category, 14.3% in the adequate category, and 74.3% in the poor category. The average blood sugar level of the respondents was 285 mg/dL. The statistical test results showed a p-value of 0.003, indicating a significant difference between the level of knowledge about diabetes mellitus and fasting blood sugar levels. Thus, this study concluded that the level of patient knowledge has a significant relationship with fasting blood sugar levels in type 2 DM patients.
Faktor Yang Mempengaruhi Kepatuhan Penggunaan Alat Pelindung Diri (APD) Pada Tenaga Kesehatan : Literatur Review Ningrum, Kurnia; Graharti, Risti; Larasati, TA
Medula Vol 16 No 3 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v16i3.1812

Abstract

Abstract The use of Personal Protective Equipment (PPE) is a key component of infection prevention and control in healthcare facilities. Compliance among healthcare workers determines the effectiveness of protection against biological, chemical, and physical hazards in the workplace. However, PPE compliance remains a challenge in many healthcare settings. This literature review aims to identify factors influencing PPE compliance among healthcare workers based on recent studies. The review was conducted using Google Scholar, PubMed, and ScienceDirect databases with the keywords “personal protective equipment,” “compliance,” and “healthcare workers.” Articles published between 2015 and 2025 were included. Of the 62 articles identified, 13 met the inclusion criteria and were analyzed in depth. The analysis focused on synthesizing findings related to individual, organizational, and work environment factors affecting PPE compliance. The results show that individual factors such as knowledge, attitude, risk perception, and work experience significantly influence compliance behavior. Organizational factors, including PPE availability, institutional policies, supervision, safety culture, and continuous training, also play an important role in shaping compliance. In addition, work environment factors such as workload, comfort of PPE, and physical conditions of care areas contribute to compliance levels. Understanding these factors is essential for improving patient and healthcare worker safety through comprehensive intervention strategies. Improving education, strengthening institutional policies, and ensuring adequate PPE supply systems are expected to enhance compliance. In Indonesia, integrated studies examining factors influencing PPE compliance remain limited, highlighting the need for further research to support policy development and occupational safety practices for healthcare workers.
Laporan Kasus: Pemanfaatan MRI pada Diagnosis Fraktur Kompresi Vertebra Akut Post-Trauma Afrida, Frecilia; Ramadhian, Ricky
Medula Vol 16 No 3 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v16i3.1813

Abstract

Vertebral compression fracture (VCF) is a common spinal injury, particularly among the elderly population with underlying osteoporosis. This condition may lead to severe pain, functional limitation, spinal deformity, and increased morbidity and mortality if not accurately diagnosed and managed. A comprehensive clinical and radiological approach is essential to establish the diagnosis and to differentiate acute traumatic fractures from chronic or pathological vertebral fractures. Magnetic resonance imaging (MRI) plays a crucial role in the evaluation of vertebral compression fractures due to its superior ability to assess soft tissues, spinal cord involvement, and bone marrow edema, which is a key indicator of acute injury. This case report describes a 68-year-old male with a known history of osteoporosis who presented to the emergency department following a fall from a height. The patient complained of severe lumbar pain and limited mobility without neurological deficits. MRI examination revealed an acute vertebral compression fracture characterized by bone marrow edema, with no evidence of paraspinal soft tissue involvement or spinal cord compression. These findings confirmed the diagnosis of an acute post-traumatic VCF in an osteoporotic patient. This case highlights the pivotal role of MRI in determining fracture acuity, evaluating spinal stability, detecting potential complications, and guiding appropriate management strategies. The appropriate utilization of MRI may improve diagnostic accuracy, facilitate timely intervention, and ultimately enhance clinical outcomes in patients with vertebral compression fractures.
Pasien Perempuan 45 Tahun dengan Ulkus Kornea Cum Hipopion Okuli Dekstra : Sebuah Laporan Kasus Aulia Ghina Sabilla; Maulana, Muhammad
Medula Vol 16 No 3 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v16i3.1815

Abstract

The cornea is a transparent, avascular layer located at the front of the eye, primarily functioning to protect the eyeball. It consists of five distinct layers: the epithelium, Bowman's membrane, stroma, Descemet's membrane, and endothelium. The corneal epithelium plays a crucial role as a barrier against infection. Damage to the epithelial layer allows external substances to penetrate the underlying tissues, potentially leading to a corneal ulcer. A corneal ulcer is a pathological condition characterized by a lesion or defect in the corneal epithelium, resulting from a loss of tissue integrity and accompanied by an inflammatory infiltrate. This condition can affect the cornea from the epithelium to the stroma and constitutes an ophthalmic emergency that can severely threaten vision. Corneal ulcers are frequently associated with hypopyon, which is an inflammatory reaction in the anterior chamber of the eye, visible as a white layer that settles at the bottom of the chamber due to gravity. In this case report, a 45-year-old woman presented with a red right eye and decreased visual acuity that had persisted for one month. The patient reported a history of ocular trauma from being struck by grass while pulling weeds. Ophthalmological examination revealed a visual acuity of 1/300 in the right eye (OD), bulbar conjunctival injection, hyperemia of the fornix and palpebral conjunctiva, positive ciliary injection, a cloudy cornea with a distinct, excavated central lesion measuring 9 mm x 7 mm, and hypopyon occupying the lower one-third (1/3) of the anterior chamber. Visual acuity in the left eye (OS) was 6/6, and the anterior segment of the OS was within normal limits. The management provided included medicamentous therapy, non-medicamentous therapy, and a plan for operative intervention. The medicamentous regimen for the right eye consisted of topical Moxifloxacin 0.5% hourly, Natamycin 5% every 3 hours, Atropine Sulfate 1% every 8 hours, Sodium Potassium Chloride every 4 hours, and systemic therapy with Ciprofloxacin tablets 2x500 mg and Ketoconazole tablets 3x200 mg.
Low Back Pain Pada Petani Karet: Sebuah Tinjauan Pustaka Pratama, Redi Bintang; Utomo, Muhammad Aditya; Utama, Winda Trijayanthi
Medula Vol 16 No 3 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v16i3.1818

Abstract

 Low Back Pain (LBP) is one of the most common musculoskeletal disorders experienced by agricultural workers, including rubber farmers, due to heavy physical demands, repetitive activities, and non-ergonomic work postures. The high prevalence of LBP among rubber farmers has the potential to reduce work productivity, increase the risk of disability, and negatively impact quality of life. This study aims to review the literature related to the incidence, prevalence, risk factors, and prevention and management efforts for Low Back Pain in rubber farmers. The method used is a literature review by searching for scientific articles through the Google Scholar, PubMed, ScienceDirect, and Garuda databases. The articles included were original studies in Indonesian and English published in the last ten years and discussed LBP in rubber farmers or agricultural workers with similar work characteristics. The results of the study showed that the prevalence of LBP among rubber farmers was relatively high, ranging from 33% to more than 70%. The main risk factors include heavy workloads, non-ergonomic work postures, repetitive work activities, prolonged standing or bending, and working without ergonomic training. Individual factors such as age, length of service, body mass index, and smoking habits also contribute to an increased risk of LBP. Recommended LBP prevention and management efforts include applying ergonomic principles at work, regulating work and rest times, occupational health education, stretching and back muscle strengthening exercises, and controlling individual risk factors. The conclusion of this literature review indicates that LBP among rubber farmers is a multifactorial occupational health problem that requires ergonomic interventions and continuous occupational health promotion.

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