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Risti Graharti
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Lampung
INDONESIA
Medula
Published by Universitas Lampung
ISSN : -     EISSN : 97726154     DOI : -
Medical Profession Journal of Lampung didirkan pada tahun 2013. Medula hadir memenuhi kebutuhan publikasi jurnal bagi mahasiswa Fakultas Kedokteran, Dosen ataupun klinisi dan profesi lain dibidang kedokteran. Medula diterbitkan dengan frekuensi 4 kali dalam setahun yang tiap nomornya mencakup 30 jenis artikel ilmiah seperti artikel penelitian, laporan kasus, tinjauan pustaka dan lain-lain. Medula sudah memiliki nomor ISSN media cetak sejak tahun 2013
Articles 906 Documents
Ruptur Tendon Achilles: Tinjauan Pustaka Helmi Ismunandar; Rani Himayani; Ranti ayu puspita Alwi
Medula Vol 10 No 4 (2021): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i4.165

Abstract

The Achilles tendon (AT) is the most frequently ruptured tendon in the human body but its etiology is poorly understood. Achilles tendon rupture (44% to 83%) occurs during sports activities, intrinsic structural, biochemical, and biomechanical changes associated with aging. The two main explanations for mechanism are degenerative and mechanical theories. The diagnosis of AT rupture is based on a history of such a sudden feeling of pain in the heel, sometimes accompanied by a pounding sound during activity. Specific physical examinations that can be done are the Simmonds or Thompson squeezed test, O'Brien's test, the matles or knee flexion test, and the Copeland test or sphygmomanometer. The diagnosis can be made by a good history and physical examination. Imaging is usually not required, as a diagnosis can be made clinically. Ultrasound or magnetic resonance imaging (MRI) can help if the diagnosis is not clear (partial rupture or tendonopathy). Non-operative and operative management may be options. The initial management of Achilles tendon rupture is rest, elevation, pain control, and functional support. For most patients with Achilles tendon rupture, the prognosis is very good. However, in some non-athletic patients, there may be some residual deficits such as reduced range of motion. No matter which method is used to treat tendon ruptures, participating in exercises is very important.
Laporan Kasus Hiperleukositosis pada Pasien Anak 7 Bulan dengan Akut Limfoblastik Leukimia (ALL) Tipe L1 Ghazlina Winanda; Rogatianus Bagus
Medula Vol 10 No 3 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i3.166

Abstract

Acute lymphoblastic leukemia (ALL) type L1 patients are the most common type found in hematolymphopoietic neoplasms. Reportedly a child aged 7 months with complaints of fever and pale. Physical examination showed hepatosplenomegaly. Investigations found an increase in leukocytes of 285,000 / µL. The results of Leukemia Phenotyping examination showed that leukemia types included ALL type L1, immunotyping showed precusor B cell, there was no gene fusion examination. Treatment for 3 days at Type A Hospital to find the right diagnosis and improve the general condition of the patient. Therapy can be given earlu and adequate for the provision of hyperlaucocytosis with aggressive hydration, alkalinization of urine and will be given chemotherapy drugs supported by stable general patients such as anemia, thrombocytopenia or leukocytosis and hyperleukocytosis. if the patient's general condition is stable, such as anemia, thrombocytopenia or leukocytosis or even hyperleukocytosis. If the patient's condition is stable, initiation of chemotherapy treatment can be started according to the Indonesian protocol ALL HR 2018. This protocol consists of an induction phase for 6 weeks, consolidation for 4 weeks, reinduction for 4 weeks, and a maintenance phase of up to 110 weeks.
Efek Anti-Mikrobial pada Ekstrak Cinnamomum verum (Kayu Manis) sebagai Terapi Adjuvant pada Malaria Falciparum Khairun Nisa; Fitria Putridewi Abidin
Medula Vol 10 No 4 (2021): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i4.167

Abstract

Malaria is a major public health problem in the world, especially in Indonesia. The prevalence of malaria in Indonesia reaches 6 percent with 2000 deaths each year, most of which are caused by Plasmodium falciparum. Various treatment options for falciparum malaria have been developed, but due to various factors, one of which is the adherence of patients who are not monitored medication, increases the risk of resistance to current malaria therapy. Therefore, the researchers conducted further research on alternative malaria therapies. Cinnamomun verum or cinnamon is known to contain cinnamaldehyde compounds which have antimicrobial properties. The purpose of this study was to determine the anti-microbial effect of Cinnamomun verum (cinnamon) extract as an adjuvant therapy in falciparum malaria. This literature review article takes 25 case report articles, research articles, and literature reviews. The conclusion of this study is that the cinnamaldehyde compound in the extract of Cinnamomun verum has an antiparasitic effect which can inhibit the denaturation potential of amino acids, inhibits β-hematin formation and activity of the reductase enzyme on Plasmodium falciparum enoyl-ACP reductase. It is known that these four things have an important role in the pathogenesis of falciparum malaria.
Hubungan Rinitis Alergi Dengan Rinosinusitis Kronik Zhafran Ramadhan Lumbantobing; Mukhlis Imanto
Medula Vol 10 No 4 (2021): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i4.168

Abstract

Chronic rhinosinusitis is an inflammatory and infectious disease of the paranasal sinuses with the characteristics of 5 major symptoms that have occurred for at least 12 weeks: nasal congestion, pain or pressure on the face, nasal obstruction, the presence of secretions in the nose anterior and posterior, and loss of smell. Allergic rhinitis is the most common predisposing factor for chronic rhinosinusitis because it is associated with obstruction of sinus ostium due to mucosal edema. As many as 50% - 84% of patients with chronic rhinosinusitis have a history of atopy to dust, fungi and allergies to animal hair and an increase in serum specific IgE antibodies and peripheral eosinophils associated with the onset of symptoms of chronic rhinosinusitis. In chronic rhinosinusitis patients with allergic rhinitis, hypersensitivity reaction occur and an increase in the number of inflammatory mediators such as histamine, proinflammatory cytokines such as interleukins, TNF-α (tumor necrosis factor), GM-CSF (granulocyte-macrophage colony stimulating factor) is more in the nasal mucosa compared with chronic rhinosinusitis patients without allergic rhinitis. All these inflammatory mediators will then lead to increased vascular permeability and hypersecretion of the mucus glands. The inflammatory process caused by allergic rhinitis will cause blockage of the ostiomeatal complex, impaired mucocilliary clearance, and impaired ciliary function resulting in paranasal sinus obstruction which will lead to chronic rhinosinusitis. It is very important for patients with allergic rhinitis to be managed properly both pharmacologically and non-pharmacologically in order to help prevent the occurrence of chronic rhinosinusitis.
Hubungan Pemakaian Inhalasi Kortikosteroid Flutikason Dengan Kejadian Eksaserbasi Pada Pasien Penyakit Paru Obstruksi Kronik Di Rumah Sakit Umum Daerah Abdul Moeloek Provinsi Lampung Periode Tahun 2015-2017 Natasya Aurum Alifia Zaini; Novita Carolia; Anggraeni Janar Wulan
Medula Vol 10 No 3 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i3.169

Abstract

Chronic Obstructive Pulmonary Disease (COPD) is a chronic lung disease with irreversible condition. One of the treatmentusing fluticasone inhaled corticosteroids shows a significant improvement in lung function, reducing symptoms andreducing exacerbations. The purpose of this study was to determine the relationship of fluticasone corticosteroid inhalationwith the incidence of exacerbations in COPD patients at Abdul Moeloek Regional Hospital in the period 2015-2017 LampungProvince. This study was an observational study that used secondary data (medical records) of 102 patients who wereanalyzed the type of the drug they used with the occurrence of exacerbations they experienced. The results of the analysisin this study showed a significant correlation between the use of fluticasone inhaled corticosteroids and the exacerbationsin COPD patients at Abdul Moeloek Hospital in 2015-2017 with a p value of 0.049 (p <0.05).
Penyakit Gagal Ginjal Kronis Stadium 5 Berdasarkan Determinan Umur, Jenis Kelamin, dan Diagnosa Etiologi di Indonesia Tahun 2018 Syahrul Hamidi N; Sofyan Musyabiq
Medula Vol 11 No 1 (2021): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v11i1.171

Abstract

Chronic kidney failure has become a very important issue in recent years due to its increasing frequency and the high costs associated with it is increasingly being seen as a major public health problem associated with premature death with important social and economic implications. In addition to early diagnosis and detection, knowledge related to the causes of hemodialysis patient mortality in Indonesia in 2018 can be used as scientific evidence in planning, program implementation, program evaluation, and determining the priority scale of the hemodialysis patient mortality prevention program in Indonesia, which is the aim of this study. . This type of research is literature review research. The target population is all hemodialysis patients in Indonesia. The affordable population in this study were all hemodialysis patients recorded in the 2018 Indonesian Renal Registry (IRR) data set. The sample of this study was all hemodialysis patients (total sampling) recorded in the 2018 Indonesian Renal Registry data set. Incidence of 3 months of mortality in new HD patients amounted to 31.7%. Age> 60 years, hemoglobin <8 g / dl, serum albumin <3.5 g / dl, ECG abnormalities, and femoral access were significant predictors of mortality in the first 3 months of HD. The comorbid conditions associated with the mortality of CKD patients undergoing hemodialysis are age, coronary heart disease, congestive heart failure, stroke, sepsis, tuberculosis, and pneumonia.
Efek Infeksi Virus SARS-CoV-2 Pada Organ Rani Himayani; Helmi Ismunandar; Aulia Khairunnisa; Gayitri Humaera; Meilisa Hidayah Putri; Novi Jayanti
Medula Vol 11 No 1 (2021): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v11i1.178

Abstract

In December 2019, an outbreak of viral pneumonia caused by a novel coronavirus (since named SARS-CoV-2) was identified in Wuhan, China. Within few months, this disease known as coronavirus disease 2019 (COVID-19) spread worldwide, causing a global health emergency. The classic routes for transmission of SARS-CoV-2 are airborne droplets and surface contamination. The clinical presentation of COVID-19 ranges from asymptomatic infection to severe respiratory failure, with fever, fatigue, and cough occurring in most cases. The pathophysiology of SARS-CoV-2 infection is complex, endotoxin and tumor necrosis factor (TNF-α) trigger the production of interleukin (IL)-6 and IL-8, which is followed by a cytokine storm. Moreover, SARS-CoV-2 binds to angiotensin-converting enzyme-2 (ACE2) receptors, which are widely distributed not only in the lung alveolar epithelial cells and nasopharyngeal and oral mucosa but also in the endothelium and vascular smooth muscle cells, in the brain, in the gut, and in peripheral organs such as the liver and kidneys. This suggests that the clinical spectrum of COVID-19 is not limited to local pneumonia, but rather represents a multisystem illness with involvement of different organs and potential for systemic complications. Keywords:Covid-19, Angiotensin-converting enzyme, Multiple Organs.
the Penggunaan Media Sosial dalam Pendidikan Kedokteran dengan Konsep E-learning: Penggunaan Media Sosial dalam Pendidikan Kedokteran dengan Konsep E-learning Della inike Putri; Evi Kurniawaty
Medula Vol 11 No 1 (2021): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v11i1.179

Abstract

Social media is one of the online media that often used by the wider community to convey information to others and play an important role in the education process. Social media also provides the concept of space to interact and share knowledge by providing group facilities for students who join and discuss various topics, collaborate and use educational applications to manage learning activities. Medicine is one of the fields that has gained an important foundation through the application of one concept such as e-learning. To formulate learning with an effective e- learning system, collaboration must occur between educational institutions, instructors and technology experts. Although the use of the internet as a learning medium is very potential, not all learning materials can be replaced through social networks. In the learning process, the use of social networking is more stimulating cognitive abilities of medical students, but the skills and motor skills to conduct physical examination, history taking, practicum, and affective assessment of students should still be done face-to-face learning.
Fibromyalgia: Tinjauan Pustaka Maula Al Farisi; Muhartono; Anggi Setiorini; M. Praditia Ansor
Medula Vol 11 No 1 (2021): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v11i1.184

Abstract

Musculoskeletal chronic pain is characterized by pain and loss of function in the joints, tendons, ligaments, bones, and or muscles lasting for greater than equal to three months. There are several diseases caused by rheumatic disorders that have been identified, such as osteoarthritis, gout, rheumatoid arthritis, fibromyalgia. However, until now, chronic rheumatic disorders have become a world problem, namely “fibromyalgia”. Fibromyalgia is a syndrome characterized by generalized chronic musculoskeletal pain, hyperalgesia in specific points and psychosomatic symptoms, such as fatigue, sleep disturbances, anxiety, depression, cognitive dysfunction, headache, and gastrointestinal disorders. The prevalence of fibromyalgia in the world is higher in women than in men, which is between 2,4% to 6,8% with the ratio between women and men is 2:1. The etiology of fibromyalgia is idiopathic, but it is suspected that psychosocial factors play a role in the development of fibromyalgia. Currently, the diagnose of fibromyalgia can only be made by a comprehensive clinical examination according to the ACR (American College of Rheumatology) criteria. Therapy of fibromyalgia requires an optimal approach to the success of treatment. Therapies that can be done in patients with fibromyalgia include pharmacological therapy, complement therapy, cognitive behavioural therapy, psychotherapy and physical therapy.
Penatalaksanaan Holistik pada Perempuan Usia 60 Tahun dengan Diabetes Mellitus Tipe 2 melalui Pendekatan Kedokteran Keluarga Sonia Anggraini; Aila Karyus
Medula Vol 11 No 1 (2021): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v11i1.185

Abstract

Diabetes Mellitus (DM) is a global public health problems, in 2014 the prevalence of DM sufferers reached 9% of the world's total population and 90% of them are DM type 2. The mortality rate for DM disease in 2012 worldwide reached 1.5 million. In 2013, the International Diabetes Federation (IDF) estimated there were 382 million people with DM in the world. Family approach in the management of diabetes mellitus helps identify factors that influence both clinical, personal and psychosocial family. This study is intended as the application of family doctor services to patients by identifying risk factors, clinical problems, and patient management based on a patient's problem-solving framework with a patient centered and family approach. This is a case report study. Primary data were collected by history, physical examination, examinations and home visits to assess the physical environment. A 60 years old woman diagnosed with type 2 diabetes mellitus with lacking knowledge of the disease, curative treatment behaviour, poor diet, rarely exercising and low physical activity and low family knowledge about diabetes mellitus. After the intervention, the patient has shown clinical improvement and changes in behavior towards the patient's disease. In the quantitative assessment, there is an increase in all aspects assessed which are knowledge, diet and physical activity. Management of diabetes mellitus patients holistically and comprehensively, patient center, family approach with diabetes mellitus treatment is needed in order to prevent acute and advanced complications.