Garuda - Garba Rujukan Digital

Hubungan Keluhan Iritasi Mata dengan Lama Kontak dan Kadar Klorin pada Air Kolam Renang Universitas Lampung Fahma Azizaturrahmah; Rani Himayani; Anggraeni Janar Wulan
Medula Vol 10 No 1 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.28

Eye irritation is an inflammation of conjunctival layer caused by exposure of irritant substances such as chemicals. Chlorine in swimming pool water is one of the chemical substances that can cause eye irritation complaint at a certain level and time. This study aims to determine the relationship between eye irritation with contact time and swimming pool chlorine levels. The research design was quantitative with cross sectional method, with sampling technique of consecutive sampling. There were 96 participants. Chlorine levels were tested with chlorine meter then eye complaint and contact time were taken from the questionnaire filling. The analysis test was performed by using chi-square test. There was correlation between eye irritation with chlorine level with result of chi-square test p value = 0,002 and odds ratio equal to 4,577. There was correlation between eye complaint with chlorine contact time with chi-square test p value = 0,04 and odds ratio 2,857. Conclusion: Participants with chlorine exposure more than standard were at risk 4,577 times to have eye irritation than participants with chlorine exposure at standard. Participants with chlorine exposure more than 15 minutes were at risk 2,857 times to have eye irritation than participants with chlorine exposure less than 15 minutes.

Hubungan Pengetahuan dan Dukungan Keluarga terhadap Status Depresi pada pasien Kanker Serviks di RSUD DR. H. Abdul Moelok Bandar Lampung Tahun 2016 Shesy sya’haya; Ratna Dewi PS; Anggraeni Janar Wulan
Medula Vol 10 No 2 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i2.55

Cervical cancer is the second most types of cancer experienced by women around the world and are most numerous in Latin America and developing countries such as Indonesia. The impact that occurs in patients with cervical cancer one of which can cause problems in people with depression. Depression will be overcome by their patients use coping mechanisms based on the resources around. Source coping is important for the patient is the knowledge and family support. The study was to determine the related knowledge and family support for the level of depression in patients with cervical cancer at the Dr. H. Abdul Moeloek Bandar Lampung Hospital in 2016. The study is analytic survey with cross sectional approach. The sampling method using purposive sampling and obtained a sample of 24 respondents. The study uses chi square test with an alpha of 0.05. Results research showed a significant relationship between knowledge with the depressed levels of cervical cancer patients were obtained by value p = 0.014 and there was a significant relationship between family support with the depressed levels of cervical cancer patients were obtained value of p = 0.023. Theres a significant relationship knowledge and family support for the level of depression in patients with cervical cancer at the Dr. H. Abdul Moeloek Bandar Lampung Hospital in 2016

Ketuban pecah dini, partus prematurus imminens, penatalaksanaan Prizka Putri Pahlawan; Rika Lisiswanti; Anggraeni Janar Wulan; Merry Indah Sari
Medula Vol 10 No 3 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i3.95

The growth of social media usage has increased almost 15 times, in line with the growth of internet usage in Indonesia in the last 10 years. Social media usage has a relationship with learning motivation, even though long duration of social media usage has impact on the decrease of learning motivation. Investigated relationship of social media usage duration with student learning motivation in class of 2015 Faculty of Medicine, the University of Lampung. Cross sectional design was applied in this research by taking primary data during period of August to September 2017, with the sample of 185 students class of 2015 Faculty of Medicine, the University of Lampung. Analysis model used was Chi-Square Analysis. Based on the statistic value of significant alpha more than 0,05, there was no relationship between social media usage duration and learning motivation. Moreover, the research result shows that learning motivation in term of intrinsic dimension was in low category with the amount of 55,14%. Beside this, leaning motivation in term of extrinsic motivation external regulation was in high category with the total amount of 56,76%. The duration of the use of social media has a positive relationship on student learning motivation because the duration of the use of social media by students of the Faculty of Medicine, University of Lampung class of 2015 is less than one hour per day and student learning motivation is in the aspect of extrinsic motivation of external regulation.

Hubungan Pemakaian Inhalasi Kortikosteroid Flutikason Dengan Kejadian Eksaserbasi Pada Pasien Penyakit Paru Obstruksi Kronik Di Rumah Sakit Umum Daerah Abdul Moeloek Provinsi Lampung Periode Tahun 2015-2017 Natasya Aurum Alifia Zaini; Novita Carolia; Anggraeni Janar Wulan
Medula Vol 10 No 3 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i3.169

Chronic Obstructive Pulmonary Disease (COPD) is a chronic lung disease with irreversible condition. One of the treatmentusing fluticasone inhaled corticosteroids shows a significant improvement in lung function, reducing symptoms andreducing exacerbations. The purpose of this study was to determine the relationship of fluticasone corticosteroid inhalationwith the incidence of exacerbations in COPD patients at Abdul Moeloek Regional Hospital in the period 2015-2017 LampungProvince. This study was an observational study that used secondary data (medical records) of 102 patients who wereanalyzed the type of the drug they used with the occurrence of exacerbations they experienced. The results of the analysisin this study showed a significant correlation between the use of fluticasone inhaled corticosteroids and the exacerbationsin COPD patients at Abdul Moeloek Hospital in 2015-2017 with a p value of 0.049 (p <0.05).

Efek Aloe vera dalam Menurunkan Risiko Penyakit Stroke Angwen Rial Huga; Anggraeni Janar Wulan; M. Yusran
Medula Vol 9 No 2 (2019): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v9i2.278

Stroke is a non communicable disease whose prevalence is increasing in Indonesia. The results of the Riset Kesehatan Dasar (Riskesdas) in 2018 showed that an increase in the prevalence of stroke from 7% (in 2013) to 10.9% with the highest proportion was in East Kalimantan (14.7%) and the lowest proportion was in the Papua region (4.1%). The increased prevalence is related to unhealthy lifestyles. Besides that hypercholesterolemia (high cholesterol levels in the blood) is also a risk factor for stroke which if not handled properly will lead to atherosclerotic plaque formation in blood vessels. This plaque can block the flow of blood that carries oxygen to the brain so that it can cause a stroke. One type of plant in Indonesia that has benefits in lowering cholesterol levels is Aloe vera. There are many ingridients of Aloe vera such as amino acids, salicylic acids, anthraquinons, enzymes, magnesiums, zincs, minerals, vitamins (A, C, E), lignins, saponins, phytosterols, monosaccharides, and polysaccharides (glucomannans and acemannans). Based on several studies, Aloe vera can reduce blood cholesterol levels with saponins, phytosterols, and glucomannans compound that have a direct role in lowering cholesterol levels. Saponin will inhibit the absorption of cholesterol in the gastrointestinal tract and increase its excretion, phytosterols will bind cholesterol and prevent cholesterol from being absorbed by the gastrointestinal tract, whereas glucomannan which is fiber will absorb water and inhibit the process of recycling bile salts so that only a few will return to the liver and more excreted through feces. Reduced blood cholesterol levels due to Aloe vera will have a good effect on atherosclerotic plaque so as to reduce the risk of stroke.

Korelasi Antara Panjang Tulang Radius Dengan Tinggi Badan Pada Pria Dewasa Suku Lampung dan Suku Jawa di Kecamatan Gisting Kabupaten Tanggamus Anggraeni Janar Wulan; Indhraswari Dyah W.
Jurnal Kedokteran Universitas Lampung Vol 2, No 1 (2018): JK UNILA
Publisher : Fakultas Kedokteran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jk unila.v2i1.1902

Proses identifikasi forensik merupakan proses penentuan tinggi badan yang merupakan langkah utama ketika hanya sebagian tubuh yang ditemukan. Salah satu cara menentukan tinggi badan adalah dengan menggunakan panjang dari tulang panjang seperti tulang radius. Penelitian ini ditunjukkan untuk mengetahui hubungan panjang tulang radius dengan tinggi badan. Penelitian ini dilakukan pada bulan Desember 2015 di Kecamatan Gisting, dengan metode deskriptif analitik dan pendekatan cross sectional. Pengambilan sampel dilakukan dengan metode non probability sampling yaitu consecutiv sampling dan memperoleh 88 responden untuk masing-masing suku Lampung dan suku Jawa. Rerata panjang tulang radius pada pria dewasa suku Lampung adalah 25,9 ± 1,469 (22-28) cm dan tinggi badan rerata pria dewasa suku Lampung adalah 164 ± 0,045 (156-179) cm dengan koefisien korelasi (r) sebesar 0.452. Panjang radius rerata pria dewasa suku Jawa adalah 25,6 ± 1,470 (22-28) cm dan tinggi badan rerata pria dewasa suku Jawa adalah 163 ± 0,045 (151-175) cm dengan koefisien korelasi (r) sebesar 0,471. Dapat disimpulkan bahwa panjang tulang radius memiliki korelasi sedang dengan tinggi badan baik pada suku Lampung maupun suku Jawa.Kata kunci:Identifikasi forensik, panjang radius, tinggi badan.

Pengaruh Pemberian Ekstrak Kulit Batang Bakau Minyak (Rhizophora apiculata) Etanol 95 % terhadap Arteri Koronaria Tikus Putih (Rattus novergicus) Jantan Galur Sprague dawley yang Dipaparkan Asap Rokok Syazili Mustofa; Nicholas Alfa; Anggraeni Janar Wulan; Soraya Rahmanisa
Jurnal Kedokteran Universitas Lampung Vol 3, No 1 (2019): JK Unila
Publisher : Fakultas Kedokteran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jk unila.v3i1.2200

Indonesia menenmpati peringkat pertama sebagai negara dengan jumlah perokok terbesar di kawasan ASEAN. Hal ini tentunya sangat memprihatinkan 2 dari 3 orang Indoneisa merupakan seorang perokok. Penyakit jantung koroner (PJK) merupakan penyebab kematian tertinggi di Indonesia setelah stroke, yakni 12,9%. Rhizophora apiculata memiliki kandungan tanin, alkaloid, dan flavonoid yang dapat mencegah radikal bebas. Dari uraian diatas, penulis ingin menggali potensi antioksidan yang terdapat dalam bakau dengan mempelajari pengaruh pemberian ekstrak kulit bakau minyak (Rhizophora apiculata) dalam melindungi arteri koroner tikus dari paparan asap rokok. Penelitian ini adalah penelitan eksperimental. Sampel yang digunakan adalah tikus putih jantan (Rattus novergicus) galur Sprague dawley yang terdiri dari 5 kelompok, masing masing kelompok terdiri dari 5 ekor tikus dan 1 cadangan. Dosis ekstrak bakau yang digunakan pada P1 adalah 28,275 mg/kgbb, P2: 56,55 mg/kgbb, P3: 113,1 mg/kgbb. Analisis statistik yang digunakan yaitu uji One Way Anova dengan post hoc Bonferroni. Rerata tebal dinding arteri koronaria memiliki hasil bermakna pada semua kelompok perlakuan. Ekstrak kulit batang bakau minyak (Rhizophora apiculata) mampu melindungi arteri koronaria tikus putih jantan (Rattus novergicus) galur Sprague dawley yang dipaparkan asap rokok. Dosis optimal ekstrak kulit batang bakau minyak (Rhizophora apiculata) dalam mencegah penebalan arteri koronaria tikus putih jantan yang dipaparkan asap rokok adalah 56,55 mg/kgbb. Kata kunci: antioksidan, arteri koronaria, asap rokok, bakau minyak Effect of Giving Mangrove (Rhizophora apiculata)

Perbedaan Kemampuan Memori Kerja Paska Paparan Gelombang Elektromagnetik Akut dan Kronis pada Tikus Putih (Rattus norvegicus) Galur Sprague dawley Anggraeni Janar Wulan; Rekha Nova Iyos; Anisa Nuraisa Djausal; Prianggara Rostu Prayoga
Jurnal Kedokteran Universitas Lampung Vol 1, No 2 (2016): JK UNILA
Publisher : Fakultas Kedokteran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jk unila.v1i2.1638

Stres adalah keadaan ketidakseimbangan yang akan mengganggu homeostasis. Stres akan memengaruhi sistem organ pada tubuh, salah satunya sistem saraf. Handphone merupakan salah satu pemicu timbulnya stres. Paparan gelombang elektromagnetik terbukti akan merusak hippocampus sebagai pusat memori. Lama paparan terhadap gelombangelektromagnetik berpengaruh terhadap kemampuan memori kerja. Penelitian ini bertujuan untuk mengetahui perbedaan nilai memori kerja paska paparan gelombang elektromagnetik akut dan kronik pada tikus putih (Rattus norvegicus) jantan galur Sprague dawley. Sampel yang digunakan adalah 18 ekor tikus putih (Rattus norvegicus) galur Sprague dawley, berusia 2-3 minggu. Sampel dibagi menjadi 3 kelompok, yaitu kelompok kontrol (K), kelompok perlakuan 1 (P1) dipaparkan dengan gelombang EM handphone selama 7 hari dan P2 dipaparkan selama 21 hari. Durasi pemaparan selama 3jam/hari. Memori kerja diukur dengan menggunakan radial arm maze. Hasil pengukuran rerata memori kerja adalah sebagai berikut K1: 1.83 ± 0,7%, K2: P1: 1,33 ± 1,0%, P2: 1.33 ± 0,5%. Dari hasil analisa Kruskal Wallis didapatkan nilai p=0,55 (p>0,05).Simpulan, tidak terdapat perbedaan memori kerja paska paparan gelombang elektromagnetik pada tikus Putih (Rattus Novegicus) galur Sprague dawley. [JK Unila. 2016; 1(2)]Kata kunci: gelombang EM, memori kerja

Kriteria Diagnostik dan Pendekatan Terapeutik pada Pasien dengan DIslipidemia Pediatri nickyta; Dyah Wulan Sumekar Rengganis Wardani; Anggraeni Janar Wulan
Medula Vol 12 No 4 (2022): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v12i4.481

Dyslipidemia or hyperlipoproteinemia is a quantitative change in the concentration of total cholesterol, its fraction, or just triglycerides in plasma. In addition, there is ample evidence to support that pediatric dyslipidemia is associated with atherosclerosis in adulthood. To reduce cardiovascular risk in adulthood, early identification and treatment is needed to reduce morbidity and mortality. Dyslipidemia itself can occur due to changes in primary lipoprotein metabolism due to genetic (primary) causes or other pathologies such as the result of accumulation of exogenous (secondary) factors. Therefore, mixed dyslipidemia results from genetic and environmental associations with risk factors for cardiovascular disease. However, lipid metabolism screening in pediatrics is not carried out in a targeted manner, causing problems where the outcome is not generally accepted. In addition, no one knows the effect of long-term pharmacological therapy. Therefore, this study aimed to review the various available literature resources on pediatric dyslipidemia to present data on a structured approach to pediatric dyslipidemia that focuses on screening, atherosclerotic risk stratification, and therapeutic approaches.

Pengaruh Pemberian Ekstrak Biji Kopi Robusta (Coffea canephora) Lampung Terhadap Aktivitas Enzim Katalase Cerebellum Tikus Putih (Rattus norvegicus) Jantan Galur Sprague-dawley yang Diinduksi Monosodium Glutamate Syifa Fakhirah Siregar; Anggraeni Janar Wulan; Dwita Oktaria
Medula Vol 13 No 5 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i5.815

Excessive consumption of monosodium glutamate (MSG) has a neurotoxic effect on the cerebellum, which will lead to a state of oxidative stress characterized by decreased activity of catalase. This study aims to determine the effect of Lampung Robusta Coffee extract (Coffea canephora) againsts to activity of the cerebellar catalase enzyme in male rats (Rattus norvegicus) strain sprague-dawley induced by monosodium glutamate. This research is a type of experimental study with a Posttest Only Control Group Design approach. The subjects were 25 rats which were divided into 5 groups which are K- (aquadest 3,5 ml/day), K+ (MSG 4 g/kgBW/day), P1, P2, P3 (MSG 4 g/kgBW/day and Lampung Robusta Coffee extract 1,5 ml/200gBW/day with a concentration of 0,03 g/ml; 0,06 g/ml; 0,12 g/ml respectively) for 14 consecutive days. The activity of the cerebellar catalase enzyme is calculated with spectrophotometer 210 nm. The average specific activity of the cerebellum catalase enzyme in K +, K-, P1, P2 and P3 were 0.00104 U/mg, 0.00154 U/mg, 0.00139 U/mg, 0.00161 U/mg, and 0.00190 U/mg respectively. One-Way ANOVA test obtained p value = 0.001 (p <0.05). Post Hoc LSD test showed a significant difference (p <0.05) between the K + and K- (p = 0.007), K+ and P2(p = 0.003), K + and P3 (p = 0.000), and P1 and P3 (p = 0.007), which means that there is an effect of Lampung Robusta Coffee extract (Coffea canephora) againsts to activity of the enzyme catalase of cerebellar in male rats (Rattus norvegicus) strain Sprague-dawley induced by MSG.

Title

Found 10 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 10 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 10 Documents
Search