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Risti Graharti
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risti.graharti@gmail.com
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Lampung
INDONESIA
Medula
Published by Universitas Lampung
ISSN : -     EISSN : 97726154     DOI : -
Medical Profession Journal of Lampung didirkan pada tahun 2013. Medula hadir memenuhi kebutuhan publikasi jurnal bagi mahasiswa Fakultas Kedokteran, Dosen ataupun klinisi dan profesi lain dibidang kedokteran. Medula diterbitkan dengan frekuensi 4 kali dalam setahun yang tiap nomornya mencakup 30 jenis artikel ilmiah seperti artikel penelitian, laporan kasus, tinjauan pustaka dan lain-lain. Medula sudah memiliki nomor ISSN media cetak sejak tahun 2013
Articles 977 Documents
Penatalaksanaan Holistik Pada Pasien Laki Laki Ex. Kuli Panggul Usia 50 Tahun Dengan Morbus Hansen Tipe Mb Dan Hipertensi Tidak Terkontrol dan Kepatuhan Pengobatan yang Rendah Melalui Pendekatan Kedokteran Keluarga Di Wilayah Kerja Puskesmas Sukaraja Raehana, Nabila Salwa; Utama, Winda Trijayanthi
Medula Vol 14 No 7 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i7.1195

Abstract

Kusta atau Morbus Hansen (MH) adalah penyakit menular kronis dengan keterlibatan yang menonjol pada kulit dan saraf yang disebabkan oleh Mycobacterium leprae. Penyakit kusta merupakan salah satu penyakit tropis yang terabaiakan yang masih banyak di dunia khususnya di Indonesia. Distribusi penyakit kusta di Provinsi Lampung pada tahun 2021 terdapat 136 kasus dan 21 kasus kusta di Kota Bandarlampung. Hipertensi adalah penyakit tidak menular yang merupakan masalah kesehatan utama di dunia maupun Indonesia. Kusta dan hipertensi dapat dihindari dan dikontrol melalui pola hidup sehat yang membutuhkan dukungan dari keluarga maupun komunitas maka dari itu penting dilakukan penatalaksanaan holistik melalui pendekatan keluarga pada pasien. Tujuan penulisan untuk menerapkan pendekatan dokter keluarga secara holistik dan komprehensif sesuai masalah yang dialami oleh pasien dan melakukan penatalaksanaan berbasis Evident Based Medicine yang bersifat patient-centered, family oriented dan community oriented. Studi ini merupakan sebuah laporan kasus. Data primer diperoleh melalui anamnesis (autoanamnesis), pemeriksaan fisik dan kunjungan rumah, untuk melengkapi data keluarga, data psikososial dan lingkungan. Data sekunder didapat dari rekam medis pasien. Penilaian berdasarkan diagnosis holistik dari awal, proses, dan akhir studi secara kualitatif dan kuantitatif. Setelah dilakukan intervensi, terdapat peningkatan pengetahuan pasien dan keluarganya mengenai penyebab, faktor risiko, serta mencegah kekambuhan pada penyakit kusta dan hipertensi. Penatalaksanaan secara holistik dapat meningkatkan pengetahuan, sikap, dan perilaku pada pasien. Selain itu, peran keluarga amat penting dalam perawatan dan pengobatan pasien serta dukungan juga diperlukan.
Pneumonia as a Secondary Complication Related to Inhaled Corticosteroid Combination Treatment for Chronic Obstructive Pulmonary Disease with Eosinophilic Phenotype Patient Wibowo, Adityo; Saputra, Tetra Arya
Medula Vol 14 No 8 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i8.1199

Abstract

Chronic obstructive pulmonary disorder (COPD) is a progressive respiratory condition characterized by chronic inflammation, proteases and antiproteases imbalance, and airway remodeling. Several hypotheses, including immune dysregulation, microbial colonization, and environmental triggers, explain the underlying cause of the deteriorating state and recurrence of exacerbations in COPD. Eosinophils, one of the inflammatory mediators, are involved in about 30% of cases of COPD. In COPD with an eosinophilic phenotype, specific therapy recommendations include inhaled corticosteroids (ICS) combined with a long-acting bronchodilator therapy typically includes the combination of inhaled corticosteroids (ICS) (e.g., fluticasone, budesonide) and a long-acting bronchodilator (LABA) (e.g., formoterol, salmeterol) to improve airflow and reduce inflammation. While ICS therapy is beneficial, side effects of pulmonary infections become more likely as the dose increases, particularly with prolonged use. The risk of pneumonia can be managed through dose optimization and careful patient monitoring.
Penatalaksanaan Holistik Penyakit Impetigo pada Anak Usia 12 Tahun di Puskesmas Kampung Sawah melalui Pendekatan Kedokteran Keluarga deralitha; Ernawati, Tutik
Medula Vol 14 No 7 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i7.1202

Abstract

Background: Impetigo is a classification of pyoderma, which attacks the epidermal layer of the skin. Impetigo is divided into two types, namely bullous and non-bullous impetigo. One of the clinical forms most often found in pediatric cases is bullous impetigo, this bacteria spreads from one individual to another through direct contact such as through hand contact. Bullous impetigo has lesions in the form of bullae and has thin walls with reddish edges, most often caused by Staphylococcus aureus. Non-bullous impetigo begins with an erythematous papulovesicle that continues to grow with a yellow crust, most often caused by Staphylococcus aureus and Group A Streptococcus. Objective: Implementing the principle of doctor service according to the problems found and carrying out holistic and comprehensive management including patient-centered and family approaches based on Evidence Based Medicine. Method: This study is a case report. The data obtained include primary data were obtained through alloanamnesis and autoanamnesis, physical examination and home visits and secondary data were obtained from the patient's medical record. Results: Patient girl 12 year old complained of brownish yellow scabs on his face and blisters filled with yellow fluid on his neck. The patient is worried that the complaint is getting worse. Clinically the patient was diagnosed with Impetigo. Next, holistic management is carried out, namely intervention using poster media. In the evaluation, results were obtained in the form of a better understanding of the disease and changes in behavior that had an impact on the success of therapy. Conclusion: The diagnosis and management of this patient has been carried out holistically and comprehensively based on several theories and recent research. In the process of changing behavior, the patient has reached the trial stage.
Penatalaksanaan Holistik Pada Anak Dengan Skabies Melalui Pendekatan Kedokteran Keluarga Di Wilayah Kerja Puskesmas Rawat Inap Way Kandis Tika, Tiara Trias; Kayrus, Aila
Medula Vol 14 No 7 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i7.1204

Abstract

Scabies is a skin disease caused by infestation and sensitization of the parasite Sarcoptes scabiei var. hominis. The prevalence of scabies in the world reaches 300 million people each year. Scabies is often ignored because it is not life-threatening. However, this disease can become chronic and cause complications, and reduce the quality of life of sufferers. Therefore, proper holistic treatment is needed using a family medicine approach to achieve successful therapy. The purpose of this article is to apply the principle of a holistic and comprehensive family doctor approach in detecting internal and external risk factors and solving problems based on EBM (Evidence Based Medicine) which is family approach and patient centered. This study is a case report. The data obtained are primary data obtained through alloanamnesis, physical examination, and home visits and secondary data obtained from the patient's medical records. An. R aged 15 years came with complaints of itching since one month ago and there were small pin-sized bumps filled with clear fluid in the itchy area which were then scratched and burst. The patient was worried that the complaint would worsen and interfere with the patient's activities. Clinically, the patient was diagnosed with scabies (ICD-10 B.86; ICPC-2: S72). Furthermore, holistic management was carried out, namely intervention using poster media. In the evaluation, the results were obtained in the form of a better understanding of the disease and behavioral changes that had an impact on the success of therapy. After holistic and comprehensive management, the patient experienced an increase in knowledge about the disease by 37.5 points. Complaints of itching and pimples on the skin decreased and the patient had improved personal and environmental hygiene.
Hubungan Antara Konsumsi Probiotik terhadap Regulasi Emosi Maharani, Atifah Fadilah; Berawi, Khairun Nisa; Graharti, Risti
Medula Vol 14 No 8 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i8.1219

Abstract

Digestion organs and brain communicate through specific pathway that involves nervous, endocrine, and immune system onto it. Guts microbiota especially probiotics holds a crucial matter in communicating with brain, that’s why it can affect one’s mood and cognitive functions by producing neurotransmitters that are related to brain through endocrine and autonomy nervous system. The consumption of probiotics is known to be able to improve the quality of guts microbial environment, where this matter has a profound impact in increasing mood so that a person can regulate their emotion better. A good emotion regulation has a beneficial impact in order to prevent and solve stress, anxiety, and depression. Psychosocial changes can be a stressor for individual so that the ability to regulate mood and emotion is needed to help a person adapt well. The aims of this study is to know how beneficial probiotics can be in individual mood changes. The relation between probiotics consuming and mood changes have been such an interest topics to be researched in order to gain knowledge and truth how it may give an enormous impact on people’s health by consuming it regularly. It is also proved by many articles and prior literatures that show the benefits of it in physical and mental aspects yet individual quality of life, vice versa it has negative impacts if it happens in a long-term period. Daily stressors are inevitable so that by knowing what could help to at least manage it. Managing how to face stressor isn’t easy for several people, thus it also can be fatal if it isn’t treated well, such as depression or even suicide.
Kista Bartholin: Laporan Kasus Rahman, M. Rizki; Shariff, Fonda Octarianingsih
Medula Vol 14 No 7 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i7.1233

Abstract

Bartholin's cyst is a type of cystic tumor that is located in the vulva and is formed due to blockage of the Bartholin's gland duct. This blockage causes fluid buildup and cystic enlargement. A report noted that a 43 year old woman came to the Obstetrics and Gynecology Polyclinic at Pertamina Bintang Amin Hospital in Bandar Lampung, complaining of a lump in the genital area that had appeared since a year ago, the size of a quail egg, but the patient stated that she did not feel any pain. The treatment given includes antibiotics and analgesics, and it is recommended to undergo a surgical procedure using the marsupialization technique. Marsupialization is a procedure in which stabilization is carried out, that is, the cyst must be stabilized and gently retracted using finger pressure applied on both sides of the affected labium, below the cyst. Then an incision is made over the body of the cyst and within the hymeneal loop, usually at the 4-5 or 7-8 o'clock position from the introitus. The incision is generally made in a cross manner and extended up to 2-3 cm according to the size of the cyst.
Uji Efektivitas Ekstrak Kulit Batang Bakau Lindur (Bruigiera gymnorrhiza) Sebagai Antibakteri Terhadap Streptococcus pyogenes Annisa Fath; Kurniawaty, Evi; Graharti, Risti; Berawi, Khairun Nisa
Medula Vol 14 No 8 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i8.1250

Abstract

The bacterium Streptococcus pyogenes is a gram-positive bacterium that causes various diseases in humans. Pharyngitis is the most common infection caused by Streptococcus pyogenes, occurring in 15-30% of children and 5-10% of adults. The extract of mangrove bark contains bioactive compounds that can serve as an antibacterial alternative.  This research is an experimental study. The mangrove bark was extracted using 96% ethanol solvent through the maceration method and subjected to phytochemical testing. The treatment consists of 96% ethanol extract preparations with concentrations of 25%; 50%; 70%; 90%; and 100%, as well as a negative control using aquades and a positive control using amoxicillin. Each treatment was repeated 4 times. Antibacterial activity testing was conducted using the well method on Muller Hinton Agar. The results of the phytochemical test showed that the 96% ethanol extract positively contained flavonoid, phenol, alkaloid, tannin, saponin, steroid, and triterpenoid compounds. The results of the antibacterial activity study from 25%, 50%, 70%, 90%, and 100% concentrations of 96% ethanol extract produced zone diameters of 4.33 mm; 5.68 mm; 6.61 mm; 7.72 mm; and 9.02 mm. These results indicate that the 96% ethanol extract of the mangrove bark has an inhibitory effect on the growth of Streptococcus pyogenes. Data analysis of the 96% ethanol extract of the mangrove bark using the One-Way ANOVA test showed p< 0.05.
Sepsis neonatal atau biasa dikenal dengan sepsis neonatorum merupakan infeksi yang melibatkan seluruh aliran darah dan semua organ-organ pada bayi baru lahir yang berusia kurang dari 28 hari. Penyakit ini masih menjadi penyebab utama morbiditas dan mort Sabila, Ghina; Apriliana, Ety; Islamy, Suryadi; Sari, Ratna Dewi Puspita
Medula Vol 14 No 7 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i7.1258

Abstract

Neonatal sepsis is a systemic infection that involves the entire bloodstream and organs of newborns, making it one of the leading causes of neonatal morbidity and mortality, particularly in low- and middle-income countries. Neonatal sepsis is classified into early-onset sepsis (EOS) and late-onset sepsis (LOS), with varying etiologies involving gram-positive bacteria, gram-negative bacteria, and fungi. This article aims to provide a comprehensive review of the etiology, risk factors, diagnosis, and management of neonatal sepsis using an evidence-based approach. This article is based on an analysis of current literature relevant to the epidemiology, pathogenesis, and treatment of neonatal sepsis. EOS is primarily caused by vertical transmission of infection during delivery, with Group B Streptococcus (GBS) as the leading cause, while LOS is often associated with nosocomial infections caused by Staphylococcus epidermidis. Risk factors include prematurity, low birth weight, invasive procedures, and poor infection control. Management involves the administration of broad-spectrum empirical antibiotics within one hour of suspected sepsis, tailored to culture results. A holistic approach, including NICU care, family education, and optimization of infection prevention, has been shown to effectively reduce morbidity and mortality. Neonatal sepsis remains a significant challenge in perinatology, necessitating comprehensive management with an evidence-based approach encompassing timely antibiotic therapy, nosocomial infection control, and family education to improve neonatal outcomes. Preventive efforts, such as enhancing perinatal hygiene and neonatal care, must be optimized to reduce the incidence of neonatal sepsis.
Pengaruh Waktu Inkubasi Terhadap Daya Hambat Ekstrak Daun Binahong Pada Cutibacterium Acnes Alvista, Valentina Nancy; Sibero, Hendra Tarigan; Aditya, Muhammad; Apriliana, Ety
Medula Vol 14 No 7 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i7.1272

Abstract

Acne (Acne vulgaris) is a common skin disorder often caused by the bacterium Cutibacterium acnes. Bacterial resistance to antibiotics used in acne treatment has become a significant concern. This study evaluated the effect of incubation time on the diameter of the inhibition zone produced by binahong (Anredera cordifolia) leaf extract in inhibiting the growth of C. acnes. The well diffusion method was employed using extract concentrations of 25%, 50%, 75%, and 100%. Data analysis was conducted using a paired t-test. The results showed a significant difference (p < 0.001) in the inhibition zones formed based on variations in incubation time. The findings indicated that longer incubation times resulted in larger inhibition zones. Binahong leaf extract was found to be effective in inhibiting the growth of C. acnes, particularly at higher concentrations and with longer incubation durations. These results demonstrate the potential of binahong leaf extract as an effective acne treatment to address antibiotic resistance.
Pengaruh Senam Zumba Terhadap Profil Antropometri dan Mean Arterial Pressure pada Mahasiswa Obesitas Universitas Lampung Lesilolo, Caroline Virgine Putri; Berawi, Khairun Nisa
Medula Vol 14 No 7 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i7.1281

Abstract

Obesity contributes for about 2.8 deaths each year and has an effect on increasing blood pressure. The prevalence of obesity in Indonesia in 2018 in adults was 21.8% and is predicted to continue to increase every year. Zumba exercise is an aerobic exercise that is proven to be effective in reducing body fat percentage by burning calories from body fat stores and effective in lowering blood pressure. Seeing the great benefits of Zumba gymnastics but the still limited research on the influence of Zumba gymnastics on the anthropometric profile and Mean Arterial Pressure (MAP) in obese individuals, researchers are interested in conducting research on the influence of Zumba gymnastics intervention on the anthropometric profile and MAP in students at the University of Lampung who are obese. This research is a quasi experimental design with a non-randomized control group pretest-posttest approach. The samples used is 26 samples for each zumba group with zumba fitness exercise treatment and the control group without zumba exercise treatment, which were taken by purposive sampling technique. The analysis is using a paired t-test parametric test and non-parametric wilcoxon test. The results showed that zumba exercise had a significant effect on the anthropometric profile Body Mass Index (BMI) with p-value = 0.000, abdominal circumference with p-value = 0.000, and MAP with p-value = 0.000. Based on the statistical results, there is a significant effect of zumba exercise on BMI, abdominal circumference, and MAP in obese students of Lampung University.