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Tangguh Okta Wibowo
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Jurnal Teknosains
Published by Universitas Gadjah Mada
ISSN : 20896131     EISSN : 24431311     DOI : https://doi.org/10.22146/teknosains.xxxx
Core Subject : Science, Engineering,
Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Industrial & Manufacturing Engineering Mechanical Engineering
Jurnal Teknosains is a peer-reviewed journal which began publication in 2011, and published each semester in June and December. It is a series of scientific publications in engineering, science and technology area. Jurnal Teknosains aims to encourage research in Science and Technology studies. Topics addressed within the journal include but not limited to: Engineering, which is divided into several topics: Mechanical Engineering, Industrial Engineering, Biomedical Engineering, Chemical Engineering, Nuclear and Physical Engineering, Civil Engineering, and Planology. Basic Sciences, which is divided into: Chemistry and Physics Health Sciences, which is divided into: Medical, Biotechnology specially in Health Science, and Dentistry
Arjuna Subject : Teknik (semua kategori) - Teknik (Lain-Lain)
Articles 8 Documents
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Search results for , issue "Vol 14, No 2 (2025): June" : 8 Documents clear
Effect of extraction, ratio, and solvent concentration on total flavonoid content and antioxidant activit of singkel (premna serratifolia linn.) using dpph method Isnindar, Isnindar; Luliana, Sri; Zahid, Muhammad
Jurnal Teknosains Vol 14, No 2 (2025): June
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/teknosains.100099

Abstract

Singkel (Premna serratifolia Linn.) is a medicinal plant commonly found in tropical regions, including Indonesia, which contains flavonoids, alkaloids, polyphenols, and triterpenoids. Flavonoids in singkel leaves act as antioxidants that can prevent oxidative stress, which is a causative factor of degenerative and chronic diseases such as cancer, arthritis, and cardiovascular diseases. This study aims to determine the effects of total flavonoid content and IC50 values in singkel leaves based on extraction methods, solvent concentration, and the ratio of extract to solvent. The methods used include maceration, soxhlet extraction, and Microwave-Assisted Extraction (MAE), with ethanol solvent concentrations of 60%, 70%, 80%, and 96%, and extract-to-solvent ratios of 1:10, 1:20, and 1:30. Antioxidant activity was measured using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method with UV-Vis spectrophotometry. The results showed that the soxhlet extraction method yielded the highest total flavonoid content of 24.56±1.81 mgQE/g with an IC50 value of 20.31±1.58 μg/mL. The 96% solvent concentration provided the best results with a total flavonoid content of 26.12±0.06 mgQE/g and an IC50 value of 15.51±2.17 μg/mL. In the solvent ratio testing, the 1:20 ratio showed the highest total flavonoid content of 19.37±0.5 mgQE/g, while the 1:10 ratio provided the best IC50 value of 11.99±1.02 μg/mL. In conclusion, the extraction method, solvent concentration, and solvent ratio significantly affect the flavonoid content and antioxidant activity of singkel leaves.
Optimizing the density of ultrafine bubbles fluid by time and production volume in a closed-loop system Budiman, Arif Adtyas; Meikayani, Jentik; Nitiamijaya, Devita; Wardhani, Veronica Indriati Sri; Setiawan, Putut Hery; Juarsa, Mulya; Prayogo, Kukuh; Baiquny, Ariq Hafizh
Jurnal Teknosains Vol 14, No 2 (2025): June
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/teknosains.100358

Abstract

Ultrafine bubbles (UFBs) play a crucial role as catalysts in water treatment, pharmaceuticals, biomedical engineering, and industrial processes, particularly those involving heat transfer mechanisms. Several researchers in Indonesia have explored ultrafine bubble fluids' potential as a heat transfer medium in passive cooling system models. In this context, changes in the density of ultrafine bubble fluids serve as the primary driver for flow. Since ultrafine bubbles increase in diameter when heated, examining an optimal production model is essential to ensure their availability in the flow. This study aims to optimize the production of ultrafine bubble fluids with the lowest possible density compared to the base fluid (reference). The research investigates the effect of production time and volume variations on ultrafine bubble density in a closed-loop system. Production times of 30, 60, 90, 120, 150, and 180 minutes are tested across tank volumes of 20, 40, 50, and 60 liters. The closed-loop production model utilizes hydrodynamic cavitation to maintain continuous fluid flow, with sample collection occurring at 15-minute intervals after the initial production time to allow for stable bubble size. Observations and statistical analysis using the Response Surface Method (RSM) reveal a nonlinear relationship between production time and ultrafine bubble fluid density. The optimal density is achieved with a production time of 60 minutes for a 40-liter volume. Additionally, this closed-loop model increases the temperature of the ultrafine bubble fluid to 54.3 °C in a 20-liter volume. Heat accumulation occurs due to the continuous pump-driven flow without additional cooling systems.
Potential of baroma rice as anti-cancer food candidate via cell cycle arrest and apoptosis Pranatami, Dwimei Ayudewandari; Akmalia, Hafidha Asni
Jurnal Teknosains Vol 14, No 2 (2025): June
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/teknosains.101243

Abstract

Cancer is a condition where the body's cells continue to divide without control. Often, this cancer is detected when it has entered an advanced stage, making it difficult to treat. Rice is a staple food widely used by more than half of Indonesia's population. The position of rice, which is a staple food, can be used as a prospective treatment to overcome the increasing number of cancer cases, especially in cases of colon cancer. Rice is reported to have many beneficial chemical contents. In cytotoxicity testing using WiDr colon cancer cells, the IC50 of the ethanolic extract of baroma rice is 316.01µg/ml. Stovetop cooked baroma rice showed an IC50 value of 672 µg/ml, while magic com cooked rice showed an IC50 value of 1232 µg/ml. Raw and stove-cooked baroma rice extracts are not strong enough to trigger apoptosis in cancer cells and can arrest the cell cycle at the G1 stage. This research shows that baroma rice extract has cytotoxic properties against WiDr colon cancer cells and various other evidence regarding the advantages of baroma rice. It is hoped that this rice can become a food that can prevent colon cancer.
Production and characterization of lactic acid bacteria biofilms synthesized using tofu wastewater Atmandaru, Susmaya; Solichah, Amalia; Retnaningrum, Endah
Jurnal Teknosains Vol 14, No 2 (2025): June
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/teknosains.103083

Abstract

Biofilms serve to protect microbes from environmental conditions. Biofilms produced by lactic acid bacteria (LAB) can even inhibit the growth of pathogens. Medium de Man Ragosa Sharpe (MRS) is a specific medium for LAB growth and biofilm formation; however, it is not effective on an industrial scale due to its high cost. Tofu wastewater serves as an alternative medium because it contains complete nutrients that support the formation of LAB biofilms. This study aimed to determine the effect of C and N formulation in tofu wastewater on the production and characterisation of biofilms produced by four Lactobacillus (LAB) strains, including Enterococcus casseliflavus F4IS5, E. casseliflavus F14IS5, and E. casseliflavus F14IS6. Glucose and ammonium sulfate were added to the tofu wastewater as carbon and nitrogen sources, respectively. The biofilm-forming ability of LAB was tested by the biofilm assay method. The LAB biofilm characteristics were tested based on adhesion, while the exopolysaccharide concentration, a component of the biofilm, was analysed using the dry weight method. The inhibitory activity of LAB biofilms against the growth of pathogenic bacteria, specifically Escherichia coli and Staphylococcus aureus, was tested using the microplate method. The highest LAB biofilm production was obtained from the E. casseliflavus F6IS4 isolate in a tofu wastewater medium supplemented with 2% glucose and 1% ammonium sulfate, with an incubation time of 48 hours. The biofilm produced was categorised as a strong biofilm, which also exhibited strong adhesion; the separate cells accounted for only 19.25%. Besides, the EPS production by the strain was 63.4%. The biofilm of E. casseliflavus F6IS4 in tofu wastewater, supplemented with 2% glucose and 1% ammonium sulfate, also exhibited the highest inhibitory activity against E. coli and S. aureus, at 2.7% and 2.1%, respectively.
Coloration study heat-cured polymer materials for denture base Setiyani, Rezki; Salim, Urip Agus; Mahardika, Muslim; Dharmastiti, Rini; Arifvianto, Budi
Jurnal Teknosains Vol 14, No 2 (2025): June
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/teknosains.104274

Abstract

The color of denture base material is important in dentistry to achieve a natural gingival aesthetic. No universal standard for denture base color, due to it difficult for dentists and dental laboratory technicians to achieve consistent results. This study proposes a method for identifying the color of artificial gums made from heated cure polymers with coloring agents. This study also examined the effect adding color agent on the hardness of denture base material and the effect of artificial saliva immersion on coloring. New coloring agents, namely pink (P), red (M), and purple (U), were added to create new colors in this study. Seven specimens from light to dark colors were made. The resulting specimens were photographed and analyzed using Adobe Photoshop software to obtain the L*, a*, and b* values for each specimen, which were then analyzed using the CIELAB formula. The results of the material hardness test showed a significant change between the immersion and non-immersion groups (p-value 0.00<0.05), while the group between 10-day and 20-day immersion showed no significant change (p-value 0.65>0.05). In materials without added color, the hardness value is 85.3 - 86.3 HSD, while in materials with added color, the hardness value increases to 85.5 - 87.7 HSD. The results of the saliva immersion test showed changes in the range of 2.51 - 5.98 for 10 days of immersion and 0.85 - 4.22 for 20 days of immersion. Based on these results, most of the color changes are still below the clinical acceptance threshold of less than 4.1. Therefore, it can be concluded that the color changes that occur after soaking are still clinically acceptable.
Noise analysis of grinding machine in the material cutting process Dharmastiti, Rini; Wijaya, Andi Rahadyan; Kurniasari, Fitri
Jurnal Teknosains Vol 14, No 2 (2025): June
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/teknosains.105448

Abstract

The handheld grinding machine used for cutting materials has generated noise that may affect the operator and individuals nearby. The noise produced by this machine needs to be analyzed to prevent potential health impacts. This study aims to measure the noise levels the handheld grinding machine generates while cutting materials such as ceramic, metal, and natural stone. Noise measurements were taken at the noise source and distances of 2 meters, 3 meters, and 4 meters from the source. A sound level meter was used for the noise measurements. The study's results indicate that the type of material being cut using the handheld grinder does not significantly affect the noise level produced. The highest noise level was recorded when cutting the plate, with an equivalent continuous sound level (Leq) of 91.6 dB at the source. The lowest noise level was recorded when cutting ceramic material, with a Leq of 89.7 dB. Statistical tests on the distance and measurement locations at 2 meters, 3 meters, and 4 meters from the source showed that the distance does not significantly affect the noise level. At distances of 2 meters and 3 meters, the average Leq for all materials was the same, ata 94.2 dB, while at 4 meters, the average Leq was slightly lower, at 93.9 dB.
Fabrication of single-axis prosthetic foot using 3d printing and resin infusion method Rahmatika S, Devi Dwi; Arifvianto, Budi; Dharmastiti, Rini
Jurnal Teknosains Vol 14, No 2 (2025): June
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/teknosains.105483

Abstract

A prototype of a single-axis prosthetic foot is proposed as an alternative prosthetic foot for patients with disabilities to perform daily activities. Three leading positions within 0-64% of the gait cycle are heel strike, midstance, and toe-off positions used as boundary conditions. The Finite Element Method can analyze a model to determine the values of deformation, stress, and strain that occur in detail. This research is conducted to fabricate an optimal prosthetic foot product or prototype and determine its strength to support the weight of the user's body and provide comfort and safety before being fabricated using 3D printing and resin infusion methods. The fabrication of the prosthetic foot prototype used Fusion 360 software and continued with simulation testing using ABAQUS 6.14 software. The prototype model was designed and evaluated to obtain strength and feasibility before being fabricated with an Anycubic Photon Mono X type DLP 3D printing machine and resin infusion method. The results obtained in this study show that the prototype of a single-axis prosthetic foot can support the human body's weight with loading level P3 or 60 kg, level P4 or 80 kg, and level P5 or 100 kg according to ISO 10328. The mass of the prototype or single-axis prosthetic foot product is 657 grams, according to the criteria, not more than 1.7% of the user's total body weight, with a hardness value of 55.5 HA, and can withstand 50,000 cycles in fatigue testing.
Characterization and mechanical properties of biocomposite of cantula fiber reinforced nano-ha/magnesium/shellac for bone screw material Triyono, Joko; Utami, Dea Pawestry; Rahardjo, Wijang Wisnu; Nugroho, Fransiskus Bima Widi
Jurnal Teknosains Vol 14, No 2 (2025): June
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/teknosains.106420

Abstract

Accidents are a major cause of fractures in Indonesia. One of treatments for fractures is bone screws with support plates that are placed on broken bone. Currently, many biomaterials for bone screws are being developed which have biodegradable properties so that post-operative bone healing is not required. The purpose of this study was to determine the effect of cantula fiber addition on tensile strength, wear rate, and crystallinity of nano-HA/magnesium/Shellac biocomposite for bone screw materials. Nano-HA/magnesium/Shellac/cantula fiber materials were mixed using a blender. The material was mixed with a magnesium/hydroxyapatite ratio of 70/30 and cantula fiber is added with variations of 0%, 10%, 20% and 30% of total volume. After that, the material mixture was compacted with a pressure of 300 MPa for 10 minutes. Then the sintering process was carried out at a temperature of 140 ̊C for two hours. The results showed that the highest tensile strength value was 7.86 MPa at 30% variation. The lowest wear rate was 0.31 x 10-3 mm3/Nm at 30% variation. The highhest crystallinity in XRD observations was obtained at 30% variation, which was 79.65%.

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