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Althea Medical Journal
Published by Universitas Padjadjaran
ISSN : -     EISSN : 23374330     DOI : 10.15850/amj
Core Subject : Health,
Medicine & Pharmacology
Althea Medical Journal (AMJ) is a peer reviewed electronic scientific publication journal which is published every 3 months (March, June, September, and December). Althea Medical Journal publishes articles related to research in biomedical sciences, clinical medicine, family-community medicine, and public health.
Arjuna Subject : -
Articles 1,068 Documents
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Association between Exclusive Breastfeeding and Child Development Ghaniyyatul Khudri; Eddy Fadlyana; Nova Sylviana
Althea Medical Journal Vol 3, No 1 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Child development highly correlates with child’s quality. The fastest child development period is during the first three years, also called golden period. This research was aimed to discover correlation between exclussive breastfeeding and child development in Cipacing Village Jatinangor, district of Sumedang.Methods: This research was conducted using cross-sectional method in thirteen Pos Pelayanan Terpadu (Posyandu) Cipacing Village in Jatinangor. One hundred and two children aged 12−24 months with their caregiver were recruited as respondents by using cluster sampling method. Hist ory of exclusive breastfeeding was assessed with questionnaire while child development status was assesed with Kuesioner Pra Skrining Perkembangan (KPSP) in September 2013 after informed consent was obtained. Chi-square test analysis was performed to determine correlation between exclusive breastfeeding and child development status.Results: Overall, children in Cipacing Village had non-exclusive breastfeeding history (83.3%), and only 16.7% respondents had exclusive breastfeeding history. Meanwhile, 89.2% of children had normal development status, and 10.8% had delayed development status. Statistic analysis using chi-square test in the level of 95% confidence between exclusive breastfeeding and child development showed p=0.686 and odds ratio 2.133.Conclusions: There is no significant relationship between history of exclusive breastfeeding and child development status. [AMJ.2016;3(1):79–84] DOI: 10.15850/amj.v3n1.726
Characteristics of Asthma Patients Seeking Care at West Java’s Top Referral Hospital, Indonesia Juan Achmad Yudistira; Emmy Hermiyanti Pranggono; Anna Tjandrawati; Primal Sudjana
Althea Medical Journal Vol 4, No 1 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: The increasing incidence of asthma in many countries in recent decades makes asthma a global health problem. The aim of the study was to determine the characteristics of asthma patients at the Respirology Outpatient Clinic of Dr. Hasan Sadikin General Hospital as West Java’s Top referral hospital. Methods: The study used a cross-sectional design. The study population was the medical record data of asthma patients at the Respirology Outpatient Clinic during June 2012–June 2013. There were 1,591 patient’s medical records at the Respirology Outpatient Clinic of Dr. Hasan Sadikin General Hospital Bandung in that period and 140 medical records were diagnosed with asthma. Seventy medical records were excluded because of inadequate data and 70 medical records were the sample of this study. The collected data were presented using percentage. Results: Seventy percent of the cases were female. From these cases 34% of patients   were aged 51–60 years. The partially controlled type was the most frequent type of asthma (62%). The most common sign and symptom was shortness of breath (86%). The most common drug used was Beta 2 agonist drugs (90%).Conclusions: The characteristic of asthma is that the patients are mostly female. Mostly the patients were in the age range of 51–60 years. The partially controlled type is the most frequent type of asthma. Shortness of breath is the most common clinical manifestation in asthma. Beta 2 agonist is the most used drug for asthma. [AMJ.2017;4(1):78–82]DOI: 10.15850/amj.v4n1.1025
Alcohol Addiction and Cognitive Function among Café Visitors at South Jakarta Andrew Suwadi; Dharmady Agus; Stefanus Lembar
Althea Medical Journal Vol 6, No 1 (2019)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (362.546 KB) | DOI: 10.15850/amj.v6n1.1604

Abstract

Background: Alcohol addiction has an acute and chronic impact, and may cause cognitive function impairment, in the form of interference in decision making and impulse control, as well as impaired motor function. Furthermore, research on alcohol addiction and cognitive function has not been widely studied in Indonesia. The purpose of this study was to explore the association between alcohol addiction and cognitive function among café visitors at South Jakarta. Methods: This was a cross sectional study, conducted among cafévisitors at South Jakarta in 2018. The respondents of this study were individuals who have consumed alcohol in the last 12 months and not consumed narcotics, psychotropic, and other addictive substances except nicotine and caffeine. Alcohol addiction among respondent was assessed by the CAGE questionnaire and cognitive function was assessed by the MoCA-Ina questionnaire. Statistical analysis was determined by Chi Square test.Results: In total, 80 respondents consisting of 57 men and 23 women met the study criteria, 67.5% of respondents have experienced alcohol addiction and 85.2% have experienced poor cognitive function. There was a strong association between alcohol addiction and cognitive function among café visitors (p=0.000; OR=44.083).Conclusions: Individual with alcohol addiction has a poor cognitive function compared with people without alcohol addiction. Therefore, awareness of the adverse effects of alcohol addiction on cognitive function among community is needed and thus, people are expected to distance from alcohol addiction.
Creatine Phosphokinase and Visual Analogue Scale as Indicators for Muscle Injury in Untrained Bodybuilders Suresh Shanmugam; Reni Farenia; Nina Tristina
Althea Medical Journal Vol 2, No 2 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Skeletal muscle is a vital tissue in the human body to enable breathing, walking and performing several sports activities. However, this muscle is persistently injured throughout every sports session. Some exercises demand a muscle injury occurrence in order to build a stronger muscle through an adaptation process namely bodybuilding exercise. Importantly, every muscle injury should occur within a physiological range which can be identified by several biomarkers as well as pain scale. The aim of this study was toidentify changes on the level of Creatine phosphokinase (CPK) and Visual analogue scale (VAS) between pre and post training sessions and the correlation between these two indicators.Methods: This was an observational analytical cross sectional comparison study which was conducted in October 2012 and the subjects were adult untrained bodybuilders at the Jatinangor fitness center. The data was obtained by measuring serum CPK and marked VAS. The data were analyzed by t-test, Wilcoxon’s test and Spearman’s correlation.Results: Both CPK and VAS increased significantly by 296 U/L and 19.9 mm respectively. There was a strong positive significant correlation between VAS and CPK (p=0.01, r = 0.711).Conclusion: The healthy untrained bodybuilders chosen in this study experienced a mild (<2000 U/L) muscle injury throughout the training sessions with general increased CPK levels and VAS measurement. [AMJ.2015;2(1):147–52]
Differences of Clinical and Laboratory Presentation in Positive and Negative Acid Fast Bacilli Pulmonary Tuberculosis Patients Amila Hanifan Muslimah; ArtoYuwono Soeroto; Enny Rohmawaty
Althea Medical Journal Vol 3, No 2 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Based on bacteria status, tuberculosis is classified into positive and negative acid fast bacilli. This study was conducted to determine the differences of clinical and laboratory presentation in positive and negative acid fast bacilli pulmonary tuberculosis patients.Methods: This study was an observational analytic study with a cross-sectional approach which used 338 medical records of patients with pulmonary tuberculosis at Direct Observational Treatment Short-course(DOTS) clinic Dr. Hasan Sadikin General Hospital from January to December 2012. Data collected were clinical and laboratory presentation for analytic study. Data about comorbid were collected for descriptive data.Results: From 338 medical records, 223 were medical records of patients with pulmonary tuberculosis and 105 medical records of patients with comorbid. Twenty (18.01%) comorbid were Human Immunodeficiency Virus (HIV). Acid fast bacilli negative was more (121, 51.9%) than acid fast bacilli positive (112, 48.1%). Differences of laboratory presentation were found in hemoglobin count (p=0.037), red blood cell count (p=0.022), and erythrocyte sedimentation rate (p=0.006) and not found in white blood cell count (p=0.073), thrombocyte count (p= 0.766), serum glutamic oxaloacetic transaminase (p=0.169), and serum glutamicpyruvic transaminase (p=0.309). Difference of clinical manifestation was not found in fever (p=1), cough (p=0.608), night sweats (p=0.09), dyspnea (p=0.210), and weight loss (p=0.269).Conclusions: Differences between acid fast bacilli positive and negative are found in hemoglobin, red blood cell, and erythrocyte sedimentation rate laboratory examination. The highest comorbid of pulmonary tuberculosis patient is HIV. [AMJ.2016;3(2):286–5]DOI: 10.15850/amj.v3n2.786
Nutritional Status Among Elderly in Ambulatory Care Setting Karina Nurizky; Putri Teesa Radhiyanti Santoso; Muhammad Apriandi
Althea Medical Journal Vol 4, No 2 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (180.155 KB) | DOI: 10.15850/amj.v4n2.1087

Abstract

Background: Nutritional status is a final outcome from a balance between food intake and body’s needs of the nutrients. Elderly is people whose age more than 60 years old. In Indonesia, elderly population has increased. Its phenomena is also known as population aging. Population aging is related to malnutrition in elderly. Malnutrition is defined as the insufficient, excessive or imbalanced consumption of nutrients.The objective of this study was to describe the nutritional status among elderly outpatients in geriatrics clinic of Dr. Hasan Sadikin General Hospital Bandung.Methods: This study was a descriptive cross-sectional study that used primary data in geriatrics clinic Dr. Hasan Sadikin General Hospital Bandung from September 2013 to October 2013. The sampling method was convenience sampling. This study was done with  43 elderly ( women, n=27 and men, n=16) outpatients.The nutritional status was classified by the questionnaire of Mini Nutritional Assessment into malnourished, risk of malnutrition and without malnutrition (adequate). After collecting the data, it was analyzed by Microsoft Excel in presenting the proportion of the elderly nutritional status.Results: Among all the respondents, 27 (63%) respondents had adequate nutrition and 16 (37%) respondents had risk of malnutrition. There was no respondent who had malnutrition (undernutrition). Conclusions: Majority of elderly outpatients in geriatrics clinic Dr. Hasan Sadikin General Hospital had adequate nutrition. DOI: 10.15850/amj.v4n2.1087
Distribution of Risks for Major Osteoporotic Fracture Based on Fracture Risk Assessment Tool in Dr. Hasan Sadikin General Hospital, Bandung, Indonesia Nik Fatin Farhana Binti Mohd Rahhim; Bambang Tiksnadi; Eppy Buchori
Althea Medical Journal Vol 2, No 3 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Osteoporosis has become a growing public health problem in Indonesia. A definite estimation of osteoporosis prevalence in Indonesia is not available due to the limited access of dual energy X ray absorptiometry (DXA) facilities.  In 2008, the World Health Organization has developed a tool called Fracture Risk Assessment Tool to identify fracture risk based on the clinical risk factors. The study aimed to identify the risk factors of osteoporotic fracture using Fracture Risk Assessment Tool in Dr. Hasan Sadikin General Hospital, Bandung, Indonesia.Methods: This descriptive study was conducted from June–December 2013 in Orthopedic & Traumatology, Internal Medicine, Geriatric and Surgery polyclinics Dr. Hasan Sadikin General Hospital, Bandung to 77 respondents, aged 40–90 years, using the random sampling method. Fracture risks were calculated online, and the data obtained were analyzed and presented using frequency distribution in tables.Results: Most of the respondents had low risk for osteoporotic fracture, and only 5.19% of them had moderate risk. The main risk factors were rheumatoid arthritis (57.14%), followed by current smoking (27.27%) and prolonged glucocorticoids consumption (25.98%).  The moderate risk group was females, above 60 years old and with normal BMI or underweight with risks of previous fracture, parent’s previous hip fracture, rheumatoid arthritis and prolonged glucocorticoids exposure.Conclusions: Majority of the respondents have low risk for osteoporotic fracture. It must be taken into consideration that increasing age, rheumatoid arthritis, current smoking, prolonged glucocorticoids consumption, previous fracture and parent’s previous hip fracture can cause increased risk. DOI: 10.15850/amj.v2n3.514
Effect of Topical Application of Binahong [Anredera cordifolia (Ten.) Steenis] Leaf Paste in Wound Healing Process in Mice Gurwinder Kaur a/p Gurcharan Singh; Novi Vicahyani Utami; Hermin Aminah Usman
Althea Medical Journal Vol 1, No 1 (2014)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Wound caused by trauma poses challenging daily clinical problems for physicians in hospitals and other health services. It has high risk for mortality and morbidity. Binahong [Anredera Cordifolia (Ten.) Steenis] plant originates from China and can be found abundantly in Indonesia. The objective of this research is to investigate the effect of topical application of Binahong leaf paste on wound healing process.Methods: A laboratory experimental study was conducted at the Pharmacology Laboratory, Universitas Padjadjaran, from October to December 2012 by using 27 Mus Muscularis mice which were divided into 3 groups: group 1 (sodium chloride 0.9%), group 2 (Binahong) and group 3 (povidone iodine 5%). Binahong leaves were crushed and were mixed with water to make a paste. The application was given for 12 days. On day zero, 1.0 cm2 of wound was incised at the back of the mice, and further on day 1, 4, 8 and 12, the percentage of wound contraction was measured. The data was analyzed using Mann-Whitney test.Results: The study indicated that the percentage of wound contraction in group 2 on day 4 (1.17%), day 8 (23.7%) and day 12 (76.14%) is the highest among all groups. The result showed that the comparison between binahong and NaCl was highly significant on day 12, p= 0.001 (p < 0.05) and the data for comparison between Binahong and povidone iodine on day 12 was significant with p= 0.003 (p < 0.05).Conclusions: Topical application of Binahong leaf paste shows better result in wound healing process of Mus muscularis mice. From this study it can be concluded that binahong promotes wound healing and can be used for home remedies for wound care and as an alternative traditional way to treat wound.[AMJ.2014;1(1):6–11]Keywords: Binahong [Anredera Cordifolia (Ten.) Steenis], povidone iodine, wound healingEfek Aplikasi pasta daun Binahong [AnrederaCordifolia (Ten.) Steenis] secara topikal dalam proses penyembuhan luka pada tikus jenis MusmuscularisLatar Belakang: Luka yang disebabkan oleh trauma menjadi masalah klinis yang menantang bagi para dokter di rumah sakit maupun bagi petugas kesehatan lainnya dalam melakukan pekerjaan sehari-hari. Luka yang timbul tersebut memiliki risiko yang tinggi terhadap mortalitas dan morbiditas. Tanaman Binahong [AnrederaCordifolia (Ten.) Steenis] berasal dari Cina dan banyak ditemukan di Indonesia. Tujuan dari penelitian untuk mengetahui efek dari aplikasi pasta daun Binahong secara topikal terhadap proses penyembuhan luka.Metode: Penelitian eksperimental ini dilakukan di Laboratorium Farmakologi, Universitas Padjadjaran, mulai Oktober–Desember 2012, menggunakan tikus jenis MusMuscularis sebanyak 27 ekor, dibagi menjadi 3 kelompok: kelompok 1 (natrium klorida 0,9%), kelompok 2 (pasta daun Binahong) dan kelompok 3 (povidone iodine 5%). Daun Binahong dihancurkan dan ditambahkan sedikit air sehingga menjadi bentuk pasta. Perlakuan diberikan selama 12 hari. Pada hari 0 dilakukan insisi pada punggung tikus untuk membuat luka sebesar 1,0 cm2. Persentase kontraksi luka akan dinilai pada hari ke-1, 4, 8, dan 12. Kontraksi luka adalah pengurangan luas pada area luka. Hasil penilaian tersebut akan dibandingkan pada tiap kelompok untuk melihat efektivitas aplikasi topikal pasta daun Binahong. Data akan dianalisis dengan uji Mann-Whitney.Hasil: Hasil penelitian menunjukkan bahwa persentase kontraksi luka kelompok 2 pada hari ke-4 (1,17%), hari ke-8 (23,7%), dan hari ke-12 (76,14%) adalah lebih tinggi dibandingkan dengan kelompok lainnya. Hasil juga menunjukkan bahwa terdapat perbedaan sangat signifikan antara perbandingan Binahong dan natrium klorida pada hari ke-12, dengan p=0,001 (p<0,05). Perbandingan antara Binahong dan povidone iodine pada hari ke-12 juga menunjukkan hasil signifikan dengan p=0,003 (p<0,05).Simpulan: Aplikasi pasta daun Binahong secara topikal menunjukkan hasil yang lebih baik dalam proses penyembuhan luka pada tikus jenis Musmuscularis. Dari penelitian ini dapat disimpulkan bahwa Binahong mempercepat penyembuhan luka serta dapat digunakan untuk perawatan luka di rumah dan sebagai cara alternatif yang bersifat tradisional untuk mengobati luka.Kata kunci: Binahong [AnrederaCordifolia (Ten.) Steenis], penyembuhan luka, povidone iodine DOI: dx.doi.org/10.15850/amj.v1n1.289
Correlation between Body Mass Index and Age at Menarche Atika Primandina Putri; Yulia Sofiatin; R. M. Ryadi Fadil; Hadyana Sukandar; Nugroho Harry Susanto; Anggraini Widjadjakusuma; Lulu Eva Rakhmilla; Lola Ilona
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: The decline of age at menarche has been reported in several countries, it occurred because of genetic, ethnic, and socioeconomic improvement in nutritional status and environment. The improvementof nutritional status has occurred globally all over the world including in Indonesia. One of the measuring tools in nutritional status is body mass index (BMI). The objective of the study was to assess the correlationbetween BMI and age at menarche.Methods: A cross-sectional study was carried out among girls aged 9–15 years old in Jatinangor, from May–November 2013. The sample of this study was chosen with cluster random sampling. Age at menarche information was collected through a questionnaire. Body mass index was calculated from measurement of body weight and height. Data was analyzed using Spearman correlation test.Results: Out of three hundred and sixty nine subjects participating in this study, sixty seven were included in the inclusive criteria. According to the classification of BMI of underweight, normal, overweight, andobese, there were 1, 55, 8, and 3 persons, respectively. Mean of BMI was 19.04 and mean age at menarche was 12.72 years, which showed a non significant result (r=-0.013; p= 0.458).Conclusions: Age at menarche was not correlated with BMI. [AMJ.2015;2(4):521–4] DOI: 10.15850/amj.v2n4.656
Lipid Profile in Type 2-Diabetic Women with Central Obesity and Non-central Obesity Scholastica Diana Nurvitasari; Nanny Natalia MS; Yovi Yoanita
Althea Medical Journal Vol 3, No 4 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Type 2 Diabetes Mellitus and central obesity are associated with higher risk of cardiovascular diseases especially in women. Lipid profile may reflect dyslipidemia which includes hypertriglyceridemia, increased level of LDL-C, total cholesterol, and reduced HDL-C level in the blood. Patients with central obesity tend to have dyslipidemia compared to those without central obesity counterpart. The study aimed at comparing lipid profile in central-obese diabetic women and non–central-obese diabetic women. Methods: This study was an analytical study with cross–sectional approach conducted in Dr. Hasan Sadikin General Hospital, Bandung, Indonesia in 2013. A total of 160 data contained of waist circumference (WC) and the level of total cholesterol, triglyceride, HDL-C and LDL-C were obtained from medical record of Diabetic patients within the period of January 2010–January 2012. Women patients whose WC of ≥80 cm were classified as central obesity while WC of <80 cm were classified as non-central obesity. The t-test was used to compare means of different variables, p<0.05 was considered as statistically significant.Results: Central obese diabetic women when compared to non-central obese diabetic women showed statistically significant increase in the level of total cholesterol serum, triglyceride serum and decrease in HDL-C serum level (p<0.05). The LDL-C serum level did not show statistical significant difference in the two groups (p>0.05).Conclusions: Diabetic patients with central obesity tend to have higher level of total cholesterol and triglyceride and lower level of HDL-C compared to diabetic patients without central obesity. [AMJ.2016;3(4):570–6] DOI: 10.15850/amj.v3n4.941

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