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INDONESIA
Medical Journal of Indonesia
Published by Universitas Indonesia
ISSN : 08531773     EISSN : 22528083     DOI : 10.13181
Core Subject : Health,
Medicine & Pharmacology
This quarterly medical journal is an official scientific journal of the Faculty of Medicine Universitas Indonesia in collaboration with German-Indonesian Medical Association (DIGM) Indexed in: IMSEAR; CAB Abstracts; Global Health; HINARI; DOAJ; DRJI; Google Scholar; JournalTOCs; Ulrichsweb Global Serial Directory; WorldCat; New Jour; Electronic Journals Library; ISJD Accredited (2013-2018) by DIKTI Kemendikbud Republik Indonesia (No:58/DIKTI/Kep/2013)
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Articles 1,648 Documents
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Validity and reliability of the Indonesian version of the Douleur Neuropathique 4 for neuropathic pain Sofyan, Henry Riyanto; Hartono, Chandra; Savitri, Irma; Alvonsius, Raymond Aris Nimrod; Hakim, Manfaluthy; Aninditha, Tiara
Medical Journal of Indonesia Vol. 34 No. 4 (2025): December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.oa.257725

Abstract

BACKGROUND The Douleur Neuropathique 4 (DN4) is a widely used questionnaire for assessing neuropathic pain, demonstrating good sensitivity and specificity across various languages. Originally developed in France, cultural and linguistic differences necessitate its translation, validation, and reliability testing before use in Indonesia. This study aimed to translate, culturally adapt, and evaluate the validity and reliability of the Indonesian version of the DN4 questionnaire (DN4-Ina) for use in clinical and research settings. METHODS Translation and cross-cultural adaptation were conducted following World Health Organization guidelines in Indonesian. A cross-sectional study was conducted in the Neurology Clinic, Cipto Mangunkusumo Hospital, to assess the validity and reliability of the DN4-Ina. The study subjects were selected through consecutive sampling of adult patients with chronic pain visiting the clinic from June to December 2023. Validity and reliability were assessed using SPSS software version 25. Validity testing utilized adjusted item-total correlation analysis, while reliability testing was evaluated using the test-retest method, intraclass correlation coefficient (ICC), and Cronbach’s alpha for internal consistency. RESULTS Of 40 participants, 65% were female, with a mean age of 51.85 (13–92) years, moderate pain intensity (mean numeric rating scale of 4.25 [2.99]), and pain duration of 7.95 (4.41) months. All DN4-Ina questions showed a correlation coefficient (r) greater than the table’s value (0.312). The reliability test showed an ICC of 0.99 and a Cronbach’s alpha of 0.746. CONCLUSIONS The DN4-Ina score is a valid and reliable questionnaire for assessing neuropathic pain in the Indonesian population.
Optimal time point for evaluation in a chronic peripheral nerve injury rat model: a preclinical study Widodo, Wahyu; Dilogo, Ismail Hadisoebroto; Kamal, Achmad Fauzi; Antarianto, Radiana Dhewayani; Wuyung, Puspita Eka; Siregar, Nurjati Chairani; Octaviana, Fitri; Kekalih, Aria; Suroto, Heri; Aprilya, Dina; Canintika, Anissa Feby
Medical Journal of Indonesia Online First
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.oa.257778

Abstract

BACKGROUND Peripheral nerve injury (PNI) can cause severe functional disabilities and progresses dynamically over time. Since evaluations held at different time points will yield different results, finding an optimal model for PNI comparison is needed. This study aimed to create an animal model of chronic denervation that simulates the progress of nerve injury. METHODS 6 male Sprague-Dawley rats underwent complete sciatic nerve transection in their right hind limbs, with severed nerve ends secured to a nearby muscle to prevent nerve regrowth. The rats were sacrificed at 2, 3, and 4 weeks. The assessment included walking analysis (pre- and post-injury), wet muscle weight measurement, and histological examination. RESULTS Progressive gastrocnemius muscle degeneration was observed at 3 different time points. Minimal degenerative changes were noted at 2 weeks, while extensive fibrosis (83.25 [12.19]% collagen area) appeared in the 4th week. The 3rd-week samples showed lymphocyte infiltrations, muscular atrophy, and progressive fibrosis, making it the best model for chronic PNI. CONCLUSIONS A 3-week chronic denervation model is proposed as a long-term PNI for further regenerative research.
Urodynamic parameters as predictors of percutaneous tibial nerve stimulation outcomes in overactive bladder patients Indraswari, Madhyra Tri; Rahardjo, Harrina Erlianti; Seno, Doddy Widyawan Hami; Mirza, Hendy; Afriansyah, Andika
Medical Journal of Indonesia Vol. 34 No. 4 (2025): December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.oa.257836

Abstract

BACKGROUND Percutaneous tibial nerve stimulation (PTNS) is an emerging overactive bladder (OAB) treatment. However, some patient characteristics can affect its effectiveness. Urodynamic studies help diagnose OAB by evaluating bladder function. This study aimed to identify prognostic factors for PTNS treatment based on urodynamic parameters. METHODS A retrospective study was performed on 108 patients with OAB who underwent PTNS at Persahabatan Hospital, Jakarta, Indonesia, between January 2022 and January 2023. Patients with primary OAB received an 8-week PTNS regimen and were grouped into success and failure. Pre-treatment urodynamic parameters were extracted and compared between groups. Additional multivariate Cox regression analysis was performed to identify risk factors associated with PTNS failure. RESULTS Of 108 patients (mean age: 51.69 [17.5]), 77 (73.1%) responded favorably to PTNS treatment. Three significant covariates of PTNS failure were identified: initial sensation volume (hazard ratio [HR]: 6.312; 95% confidence interval [CI]: 1.94−20.49), detrusor overactivity (DO) (HR: 8.476; 95% CI: 1.89−38.095), and infravesical obstruction (IVO) (HR: 5.213; 95% CI: 1.40−19.41). CONCLUSIONS Urodynamic predictors including abnormal first sensation volume, DO, and IVO were observed as risk factors for PTNS failure. These findings can help medical professionals personalize PTNS treatment, enhancing patient outcomes and satisfaction.
Patient-reported outcomes and quality of life after pelvic organ prolapse surgery in Indonesia Hakim, Surahman; Hadinata, Valencia; Wiguna, Igor Ian; Tanoto, Kevin; Amelia, Safira; Kadarusman, Adib Kamil Putra
Medical Journal of Indonesia Online First
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.oa.258009

Abstract

BACKGROUND Pelvic organ prolapse (POP) is a common condition in older women that significantly impacts quality of life (QoL). Traditional surgical success measures primarily focus on anatomical outcomes, but patient-reported outcomes provide offer a more comprehensive assessment of symptom relief and overall well-being. This study aimed to evaluate patient-reported outcomes and QoL with the Pelvic Floor Disability Index (PFDI-20) and Pelvic Floor Impact Questionnaire (PFIQ-7) following POP surgery. METHODS This cross-sectional study analyzed secondary data from medical records and patient interviews at Cipto Mangunkusumo Hospital, Jakarta. Patients diagnosed with POP who underwent surgery were followed up at 1, 3, 6, and 12 months postoperatively. PFDI-20 and PFIQ-7 scores were used to assess symptom impact and QoL. RESULTS Among 34 patients, the most common surgical method was total vaginal hysterectomy (79%), followed by colpocleisis (59%), and sacrospinous hysteropexy (6%). Postoperative PFDI-20 scores showed 76% of patients experienced minimal to no impact, while PFIQ-7 scores indicated 91% reported minimal to no impact on their QoL. 2 patients reported moderate impact, particularly in the urinary domain. No patients experienced severe or very severe impairment at any follow-up interval. CONCLUSIONS Incorporating patient-reported outcomes with anatomical assessments provides a more accurate evaluation of surgical success in POP based on PFDI-20 and PFIQ-7 scores. Because POP is a multidimensional condition, assessing surgical outcomes requires a multimodal approach that considers symptom relief and QoL.
A case of mixed mechanism glaucoma: diagnostic and management challenges Iskandar, Ferdy; Oktariana, Virna Dwi; Aziza, Yulia
Medical Journal of Indonesia Vol. 34 No. 4 (2025): December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.cr.258092

Abstract

Mixed mechanism glaucoma occurs when secondary causes contribute to glaucoma in an eye with preexisting primary open-angle glaucoma (POAG) or primary angle-closure glaucoma. This study highlights its diagnostic and management challenges. A 63-year-old female presented with blurry vision and right eye pain for 2 months. She had undergone cataract surgery in the right eye 6 months earlier and developed elevated intraocular pressure (IOP) afterward. Her visual acuity in the right eye was hand movements, and IOP was 34 mmHg despite medications. Examination revealed signs of uveitis, leading to a diagnosis of secondary glaucoma. A glaucoma drainage device (GDD) was implanted, successfully controlling IOP. Follow-up revealed POAG signs in the left eye, prompting a revised diagnosis of mixed mechanism glaucoma in the right eye. GDD implantation was effective, but continued monitoring remained essential to maintain the target IOP.
Continuous reflection in medical education: forming doctors who are both professional and humanist Prasetyono, Theddeus Octavianus Hari
Medical Journal of Indonesia Vol. 34 No. 4 (2025): December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.ed.258566

Abstract

[No abstract available]
Front & Back Matter of Indonesia, Medical Journal
Medical Journal of Indonesia Vol. 34 No. 4 (2025): December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Acknowledgment of Reviewers of Indonesia, Medical Journal
Medical Journal of Indonesia Vol. 34 No. 4 (2025): December
Publisher : Faculty of Medicine Universitas Indonesia

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Abstract

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