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INDONESIA
Nexus Kedokteran Klinik
Published by Universitas Sebelas Maret
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Core Subject : Health,
Medicine & Pharmacology
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Articles 334 Documents
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Perbedaan Kejadian Asfiksia Neonatorum pada Kehamilan dengan Preeklamsia Ringan dan Kehamilan Normal di RSUD Dr. Moewardi Surakarta Louis Hadiyanto; . Darto; Nur Hafidha Hafidha
Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: The incidences of early neonatal death and stillborn are high despite decreased overall child mortality rate. Asphyxia is one of causes of neonatal deaths. Hypertension in pregnancy (preeclampsia) may contribute to perinatal morbidity and mortality. Placental ischemia is proposed to be cause of preeclampsia as well as mechanism leading to neonatal asphyxia. This study aimed to compare the prevalences of neonatal asphyxia in pregnancies with mild preeclampsia and normal pregnancy at RSUD Dr. Moewardi Surakarta. Methods: This was an observational analytic study with cross-sectional approach, conducted from April to August 2012. Thirty patients with mild preeclampsia and 30 patients with normal pregnancies were selected based on certain criteria. Preeclampsia patients were identified from signs of hypertension (systolic/diastolic blood pressure ?140/90 mmHg), extremity edema, and/or proteinuria. Neonatal asphyxia was identified from APGAR scores documented in medical record. Data were analyzed by Fishers exact test using SPSS version 13.0 for Windows. Results: Only 1 (3.3%) case of neonatal asphyxia was found in pregnancy with mild preeclampsia. No neonatal asphyxia was found in normal pregnancy. Result from Fishers exact test showed a p-value of 1.000 (p>0.05). Conclusion: There was no difference of neonatal asphyxia prevalence in pregnancies with mild preeclampsia and normal pregnancy at RSUD Dr. Moewardi Surakarta. Keywords: Mild preeclampsia, normal pregnancy, neonatal asphyxia
Perbandingan Stres yang Dirasakan Pasien Asma dan Pasien PPOK di RSUD Dr.Moewardi Amelia Yunita; Ana Rima Setijadi; . Widardo
Nexus Kedokteran Klinik Vol 3, No 1 (2014): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Asthma is a chronic inflammatory disorder of the airways with episodic symptom such as cough, shortness of breath, wheeze, and uplifted chest. Chronic Obstructive Pulmonary Disease (COPD) is a disease which is characterized by airflow limitation that is not fully revesible and associated with an abnormal inflammatory response of the lung to noxious particles or gases. This study aimed to compared the perceived stress between asthma patients and COPD patients. This analytic study was observational using cross-sectional approach. A sample of 60 study subjects was selective by purposive sampling from outpatient who visited Pulmonary Clinic, RSUD Dr. Moewardi and fulfill the intrinsic criteria. The data was collected by interview using a set of questioner. The data was analyzed using Chi Square test on SPSS 20 for windows. This study showed that asthma patients had a low stress level, which is 60%. While, in COPD patients had high stress level, which is 63.33%. (p=0.002, OR= 7.5) There is a statistically significant difference perceived stress between asthma patients and COPD patients. COPD patients had higher stress level compared to asthma patients.
Perbandingan Sensitivitas dan Spesifisitas antara Pengukuran Lingkar Lengan Atas, Lingkar Pinggang dan Lingkar Leher untuk Identifikasi Anak dengan Obesitas Cempaka Irawati; Hari Wahyu Nugroho; Dyah Ratna Budiani
Nexus Kedokteran Klinik Vol 3, No 2 (2014): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Childhood obesity is a global phenomenon. Oneoften childreninthe worldare over weight. Then in Indonesia, the prevalence of childhood obesityis relatively increasedyear to year. Screening forobese childrenneeds to be doneearly, given thatobesity inchildhoodis likely to leadtoadultobesitylater. Anthropometric measurements are easy and inexpensive way. Therefore, there was some studies using anthropometryas the tool for identify obesityin addition to body mass index(BMI), which is the gold standard. However, there is no studies have compared the validity of assorted anthropometricas a tool to identify obese children, so that there searcherintends to compare the sensitivity and specificity between mid-upper arm circumference (MUAC), waist circumference (WC), and neck circumference (NC) in identification obese children. Methods: This study is observational analytic cross sectional approach. A sample included 72 children who were aged 6 to 12 years from four elementary school in Surakarta. Sampling population was obesity and healthy children (controls) who selected by simple random sampling had been carried out previously by fixed disease samples. Then the child was measured height, weight, MUAC, WC, and NC. Height and weight will be converted into BMI to determine obesity or not. Data were analyzed with diagnostic tests are grouped in table 2x2. From diagnostic test, we can determine the sensitivity and specificity. Furthermore, data were analyzed by Chi Square test and analysis receiver operating characteristic curve (ROC) to determine accuracy. Results: Among 72 children, 51,4% are male. MUAC (? percentile 90th), WC (? percentile 90th) and NC (cut off point 27,0-31,5) are significantly correlated with BMI. The sensitivity of MUAC was 58,33% with specificity 100%. The sensitivity of waist circumference was 66,67% with specificity 97,22%. The sensitivity of the neck circumference was 80,56% with specificity 63,89%. Conclusions: MUA Cisthe best measuring tool to identification obesityin children because it hasthe highest specificity, that is 100%. Keywords: Mid-upper arm circumference, waist circumference, neck circumference, obesity, children
The Relationship between Active Smokers Status and Spermatozoa Motility in Sekar Moewardi Fertility Clinic in Surakarta Bima Kusuma Jati; Slamet Riyadi; Vitri Widyaningsih
Nexus Kedokteran Klinik Vol 4, No 1 (2015): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Bacground: Infertility problem occurs on 15% couples. Fifty percent (50%) of the problem is caused by male. Cigarette smoking can increase free radical and cause spermatozoa oxidative stress. The study aimed to investigate the relationship between active smokers and spermatozoa motility in Sekar Moewardi Fertility Clinic in Surakarta. Methods: The cross-sectional analytic study was performed on 72 men aged 20-45 years who had semen analysis in Sekar Moewardi Fertility Clinic in Surakarta during 2014. Active smoker history was obtained by self reported questionnaire, and spermatozoa motility was obtained by medical record of the semen examination from the laboratory. Subjects were divided into active smokers and nonsmokers. The data was analyzed with SPSS 20.0 for Windows using Chi Square method. Results: The total number of active smokers was 39 (28%) and nonsmoker was 44 (61%). Subjects with motile spermatozoa were 47 (65%) and nonmotil spermatozoa were 25 (35%). It was found that there was no significant relationship (p = 0.247; RR = 1.45) between active smoker status and spermatozoa motility in Sekar Moewardi Fertility Clinic in Surakarta. The study also showed that spermatozoa motility was related to neither BMI nor age in all subjects. Conclusion: There was no significant relationship between active smoker status and spermatozoa motility in Sekar Moewardi Fertility Clinic in Surakarta. Further studies are needed to confirm and determine other risk factors which can decrease sperm parameter. Keywords: cigarrete, smoker, motility, spermatozoa, semen
Hubungan Frekuensi Bangkitan dengan Skor Kualitas Hidup pada Penderita Epilepsi Umum di RSUD Dr. Moewardi Fillisita Chandramalina Dewayani; Diah Kurnia Mirawati; Endang Sutisna Sulaeman
Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Epilepsy is a chronic neurology disease. When epilepsy was not well-controlled, it could cause so many effects such as decreasing quality of life score. The aim of this study was to find out the relation between seizure frequency and quality of life score of general epileptic patients in Dr. Moewardi hospital. Methods: This was an observational study with analytic cross-sectional approach conducted from July to August 2012 at Neurology Department of Dr. Moewardi hospital. Samples were taken by purposive sampling after selected based on inclusion and exclusion criteria. The frequency of seizure was recorded by medical record. The quality of life was assessed by QOLIE-31 questionnaire. Score of seizure frequency and quality of life were analyzed with one-way ANOVA models by SPSS 17.0 for Windows. Results: There were 30 samples consist of 13 women and 17 men. The average of quality of life total score in high seizure frequency was 59.56 4.71, medium seizure frequency was 78.32 2.20, and seizure free was 83.40 2.34. There was a negative relationship between seizure frequency and quality of life score on patients with general epilepsy. Analysis by one-way ANOVA/Kruskal Wallis showed a statistically significant relationship (p < 0.05) for total score component and the other seven components. Conclusion: Patients with higher seizure frequency had lower quality of life score. Keywords: seizure frequency, quality of life score, general epilepsy
THE RELATIONSHIP BETWEEN OBESITY WITH RISK INCIDENT OF OBSTRUCTIVE SLEEP APNEA Helmi Fakhruddin; Jatu Aphridasari; Heni Hastuti
Nexus Kedokteran Klinik Vol 5, No 2 (2016): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Introduction : The purpose of this research is to determine the relationship between obesity and risk incident of Obstructive Sleep Apnea (OSA). This research was conducted at the Medical Faculty Sebelas Maret University of Surakarta from October 2015 to November 2015. Methods : This research was an analytical research using cross sectional approach. The size of population was 200 while the size of sample was 100 people. The sampling techniques used purposive random sampling. The data were obtained by questionnaire, research instrument with a guided interview technique using weighting machine, and microtoise. The obtained data were presented in tabular form and analyzed using the Chi Square Test at the level of significance ? = 0,05. Results : From the result of research conducted in the Medical Faculty of Sebelas Maret University Surakarta from October 2015 to November 2015, it was obtained that subjects with obesity who had high risk of OSA was 29 people (78%). This number was more than the number of subjects with obesity who had low risk of OSA of 21 people (33%) from the total of 50 subjects with obesity. While the number of subjects who didnt have obesity with high risk of OSA was 8 people (22%). This number was fewer than the number of subjects who didnt have obesity with low risk of OSA of 42 people (67%). The results of data analysis obtained X2= 18,198 and OR= 7,25; so that it could be concluded statistically, that there was a relationship between obesity and risk incident of OSA. Conclusions : The conclusion from this research was there was relationship between obesity and risk incident of OSA. Keyword: Obesity Obstructive pulmonary disease Obstructive Sleep Apnea (OSA)
Hubungan Derajat Aktivitas Fisik pada Laki-Laki dengan Kejadian Stroke Iskemik di RSUD Dr Moewardi Surakarta Yusuf Budi Hermawan; Agus Soedomo; Lilik Wijayanti
Nexus Kedokteran Klinik Vol 2, No 3 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background : Stroke is a disease caused high morbidity and mortality rate in low-middle income countries. Low physical activity is one of the risk factors for ischemic stroke. The impact of low physical activity is high level of NADPH, atherosclerosis, and vascular elasticity disorder. Global Physical Activity Questionnaire version 2 (GPAQv2) is a questionnaire released by WHO which has been especially designed to measure the physical activity of people in developing countries. The aim of this study is to determine the correlation between man physical activities and ischemic stroke in Dr Moewardi Hospital Surakarta. Methods: This was an analytical observational study with case control approach. This study was conducted during May - July 2013 at the Neurology Department of Dr. Moewardi Hospital Surakarta. Subjects were acute ischemic stroke patients in neurology ward of Dr. Moewardi Hospital Surakarta which were taken by using fixed disease sampling. Data were collected by interviewed patients based on GPAQv2 questionnaire. Data analysis used multivariate with double logistic regression and have been processed by Statistical Product and Service Solution (SPSS) 16.00 for Windows. Results: This study showed statistically significant (p=0,036) between man physical activities and acute ischemic stroke in Neurology Department Dr. Moewardi Hospital Surakarta. Age and smoking as comfounding factors have been controlled. Male patients with low physical activity had 13.95 times (OR = 13.95; CI 95% 1.19 163.58) to develop ischemic stroke than ones with adequate physical activity. Conclusion:Men who use to have less physical activity more likely to develop ischemic stroke. Keywords : level of physical activity, acute ischemic stroke, GPAQv2
Hubungan Antara Kejadian Abortus Spontan dengan Kadar Hemoglobin di RSUD Dr. Moewardi Andreas Peter Sitorus; Eriana Melinawati; Dyah Ratna Budiani
Nexus Kedokteran Klinik Vol 3, No 2 (2014): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background : Many cases of abortions are caused by abnormal hemoglobin levels. World Health Organization (WHO) estimates that 35-75% of pregnant women in developing countries and 18% of pregnant women in developed countries undergo anemia while being pregnant. The purpose of this study is to determine the relationship between the incidence of spontaneous abortion with hemoglobin levels. Methods : This study is an analitic observational study with cross-sectional design. Its population are pregnant women who had been treated at the Obstetrics and Gynecology of Dr. Moewardi General Hospital. Subjects were taken with purposive random sampling technique. The data were collected using direct observation and subjects medical records. Data were analyzed using Chi Square. Results : The results of this study found 40 subjects due to the case of this study. Subjects with anemia who did not experience abortion counted only 2 people (5.0%) and subjects who experienced abortion counted as many as 17 people (42.5%). While subjects with normal hemoglobin levels who did not experienced abortion aggregates to 18 people (45%) and subjects who experienced abortion counted as many as 3 people (7.5%). The calculation obtained p-value = 0.000 <0.05, and OR = 0.020, which means there is a relationship between the incidence of spontaneous abortion with hemoglobin levels. Conclusions : There is a significant relationship between the incidence of spontaneous abortion with hemoglobin levels. Low hemoglobin levels will increase the risk of abortion.Keywords: abortion, hemoglobin levels, anemia
Hubungan Gagal Ginjal Kronik dengan Tebal Parenkim Ginjal pada Pemeriksaan USG Abdomen Fokus Ginjal Nur Alfiani; . Suyono; . Balgis
Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Complication that often occurs in chronic renal failure is the reduction of the kidney size. It widely associates with the thinning of the renal cortex due to pathological process. Unlike the cortex, the pathological process which occurred in renal medulla in chronic renal failure has not fully understood yet. Not many studies have examined the association of chronic renal failure with renal parenchyma overall. Therefore, this study aimed to determine the relationship of chronic renal failure with renal parenchyma width on abdomen USG renal focus. Method: This study was an analytical observational research with cross-sectional approach. Sample were taken using fixed-exposure sampling. Sample consisted of 30 subjects were divided into two groups, chronic renal failure and non chronic renal failure. Samples were then measured for renal parenchyma width using abdomen USG renal focus. The data were analyzed with independent-sample t test. In addition, to control confounding factor that could affect renal parenchyma width, age was selected to be controlled using multiple linear regression analysis. All of the data were analyzed using SPSS 17.0 for windows. Result: Patients with chronic renal failure had renal parenchyma width 7.922.57 mm (p = 0.001), while patients non chronic renal failure had renal parenchyma width 15.641.85 mm ( p = 0.001). Furthermore, based on the calculation, the multiple linear regression analysis showed the model equation Y = 16.78 7.95 X1 1.72 X2. The coefficient of determination (R2) of the regression analysis obtained a value of 0.781 means that 78.1% variation in the parenchyma width (Y) can be explained by variations contained in the chronic renal failure (X1) and age ?54 years old (X2), while 21.9% is explained by other variables not included in the model equations. Conclusion: This study reveals that there is significant correlation between chronic renal failure and renal parenchyma width (p < 0.05), where chronic renal failure patients have renal parenchyma width thinner than the non chronic renal failure patients. Keywords: Chronic Renal Failure, Renal Parenchyma Width, Age, abdomen USG
In Vitro Differentiation of Antifungal Effect in Herbal Toothpaste and Non Herbal Toothpaste against Candida albicans Elsa Candra Rafsyanjani; Risya Cilmiaty Arief Riswiyanto; Sri Haryati
Nexus Kedokteran Klinik Vol 5, No 1 (2016): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Introduction: Beside sodium monofluorophosphate, herbal toothpaste contained betel leaf extracts and lime extracts which were active composition of toothpaste. This research aimed to know in vitro differentiation of antifungal effect in herbal toothpaste and non herbal toothpaste against Candida albicans. Methods: This study applied an analytical experimental method. The subject of this research were cultured Candida albicans and taken by purposive randomized sampling. Toothpastes used in this study were toothpaste with 1 herbal ingredient, toothpaste with 2 herbal ingredients and non-herbal toothpaste. This research used 16 treatment groups by giving toothpaste solution with concentration of 20%, 30%, 50%, 70% and 90%, and this was also given ketoconazole 25 g/ml as positive control. Concentration expressed as weight per volume (w/v). This research was repeated three times to minimize the occurrence of bias. The plate was incubated at 37C for 24 hours and then formed inhibitory diameter zone was measured. The data was analyzed using One-Way ANOVA test, then this was continued by Least Significant Differences (LSD) Post-Hoc test. Results: One-way ANOVA test showed that there were differences of antifungal effect in herbal toothpaste and non herbal toothpaste (p = 0.003). Compared to non-herbal toothpaste, toothpaste with 1 herbal ingredient had significant differences started in concentration of 70%. Toothpaste with 2 herbal ingredients had significant differences started in concentration of 50%. Meanwhile, toothpaste with 2 herbal ingredients had significant differences compared to toothpaste with 1 herbal ingredient started in concentration of 90%. Conclusions: The antifungal effect in both herbal toothpaste and non herbal toothpaste were different. However, the significant differences appeared significantly in different concentrations. Keywords: Antifungal effect, herbal toothpaste, non herbal toothpaste, Candida albicans

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