cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
-
Contact Email
-
Phone
-
Journal Mail Official
-
Editorial Address
-
Location
Kota surabaya,
Jawa timur
INDONESIA
Indonesian Journal of Tropical and Infectious Disease
Published by Universitas Airlangga
ISSN : 20851103     EISSN : 23560991     DOI : -
Core Subject : Health, Science,
Earth & Planetary Sciences Health Professions Medicine & Pharmacology Public Health
This journal is a peer-reviewed journal established to promote the recognition of emerging and reemerging diseases specifically in Indonesia, South East Asia, other tropical countries and around the world, and to improve the understanding of factors involved in disease emergence, prevention, and elimination. The journal is intended for scientists, clinicians, and professionals in infectious diseases and related sciences. We welcome contributions from infectious disease specialists in academia, industry, clinical practice, public health, and pharmacy, as well as from specialists in economics, social sciences and other disciplines.
Arjuna Subject : -
Articles 8 Documents
 1 
Search results for , issue "Vol. 13 No. 2 (2025)" : 8 Documents clear
Correlation between Probable or Non-Probable Leptospirosis with Laboratory Findings: Based on Leptospirosis Case Definition and Faine Criteria Citra Saputra, Rada; Mahmuda, Iin Novita Nurhidayati; Utami, Musrifah Budi; Pinakesty, Angiesta; Mubaraq, Syahrun El; Srirojanakul, Sirada
Indonesian Journal of Tropical and Infectious Disease Vol. 13 No. 2 (2025)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v13i2.56564

Abstract

The incidence of leptospirosis is increasing globally, and developing countries are no exception. Leptospirosis cases are called the tip of the iceberg phenomenon, even though misdiagnosis, underdiagnosis, and underreporting still occur in health services. Thus, it leads to delays in leptospirosis treatment and may result in increased mortality rate from severe leptospirosis infection (Weil's disease). This study was to establish an accurate diagnosis by optimizing the Faine criteria. This study used an analytical observational design with a cross-sectional approach to examine faine criteria and laboratory examinations. We collected data from medical records from the Karanganyar General Hospital and the PKU Muhammadiyah Surakarta Hospital. We processed the data using SPSS version 25. The total number of samples was 42. They were divided into women (19%) and men (81%). Based on the definition category of leptospirosis cases, there were 2.4% probable group (score criteria faine part A 20-25) and 97.6% not-probable group (score criteria faine part A <20). Bivariate analysis (Chi-Square test) showed that there was no significant correlation between Faine Part A criteria and serological tests in both groups (p=0.874) as well as Hb (p=0.522), thrombocytopenia (p=0.265), leukocytosis (p=0.197), and neutrophilia (p=0.710). Loss of sodium and potassium didn’t show significant data (hyponatremia p=0.174; hypokalemia p=0.311; hypocalcemia p=0.131) not as in tropical diseases. The approach to diagnosis of leptospirosis cannot be performed using only Part A criteria, Faine, even though the patient was included in the probable definition category, even though the Faine Part A criteria score is 20-25 or ≥26.
The Relationship between Personal Hygiene and the Incidence of Tinea Versicolor among Students at Madrasah Ulumul Quran (MUQ) Pagar Air Islamic Boarding School Putra, Teuku Romi Imansyah; Yusuf, Muhammad; Maulana, Hafidh; Wali, Amran
Indonesian Journal of Tropical and Infectious Disease Vol. 13 No. 2 (2025)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v13i2.57381

Abstract

Tinea versicolor is an infectious dermatological condition caused by fungi, affecting a substantial proportion of the global population. It is particularly prevalent in tropical regions, including Indonesia. Madrasah Ulumul Quran (MUQ) Pagar Air Islamic Boarding School is a densely populated area where students often exhibit poor hygiene practices, potentially increasing the incidence of the disease. The etiological agent responsible for this infection is the Malassezia furfur species, which can be prevented through the adoption of proper personal hygiene behaviors. This study aims to determine the association between personal hygiene and the incidence of Tinea versicolor at MUQ Pagar Air Islamic Boarding School. This is an observational study using a crosssectional design. Data collection was conducted through interviews using questionnaires. The diagnosis of Tinea versicolor was based on the results of the 10% KOH examination. Sixty students from grades X, XI, and XII participated in the study, of which six were diagnosed with Tinea versicolor. The study found that the majority of the population performed good personal hygiene, with only 10% of the subjects diagnosed with Tinea versicolor. Chi-square analysis revealed a p-value of 0.000 (<0.05), indicating a significant association between personal hygiene and the incidence of Tinea versicolor at MUQ Pagar Air Islamic Boarding School. The majority of students at MUQ Pagar Air Islamic Boarding School practiced good personal hygiene and did not have a Tinea versicolor infection.
Current Profile of Vivax Malaria in Isolated Area of Kualuh Leidong Pasaribu, Ayodhia Pitaloka; Jimanto, Vincent; Ainur, Framita
Indonesian Journal of Tropical and Infectious Disease Vol. 13 No. 2 (2025)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v13i2.58715

Abstract

The Indonesian Ministry of Health targets to eliminate malaria by 2030. Vivax malaria, a challenging variant to eradicate, is prevalent in areas near elimination, including North Sumatra, which ranks fourth in malaria cases in Indonesia. Labura district, a part of North Sumatra, had a low-endemic status until 2020. However, an increase in cases occurred in 2021 within the Kualuh Leidong subdistrict, the primary contributor to Labura's malaria cases. This shifted the endemicity status from low to moderate. The objective of the study is to assess the malaria case profile in this region. A descriptive approach was used, employing a total sampling method at Tanjung Leidong Health Center between September 2022 and July 2023. This observational study identified 494 vivax malaria cases. Predominantly affecting males (60.9%), cases peaked in adults (>18 years) with 314 cases (63.6%). Microscopic examination was the leading diagnostic tool, used in 463 cases (93.7%). The health center primarily administered national regimen therapies dihydroartemisinin-piperaquine (DHP) + primaquine in 204 cases (62.4%), whereas others received alternate therapies. All patients recovered without referrals. Over 11 months, seven recurrence cases emerged, with five receiving quinine+primaquine. Vivax malaria cases in Kualuh Leidong have seen a significant increase compared to previous years. The attention and collaboration of all parties, both from the health center and the community, are necessary to achieve malaria elimination by 2030.
Update on The Current Management of Drug Resistant Tuberculosis (DR-TB) Simbolon, Rohani Lasmaria; Simatupang, Elvando Tunggul Mauliate; Yovi, Indra; Fauzi, Zarfiardy Aksa
Indonesian Journal of Tropical and Infectious Disease Vol. 13 No. 2 (2025)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v13i2.59075

Abstract

Drug-Resistant tuberculosis (DR-TB) is a global public health threat that requires a comprehensive response from all parties. DR-TB cases are often overlooked and tend to increase every year. Efforts to overcome DR-TB cases began in 2009 with the use of a molecular test, Xpert MTB/Rif, as a diagnostic tool. This has now been developed with the procurement of a molecular test with Xpert MTB/XDR. This diagnostic update also formed the basis of the latest DR-TB classification terminology by not categorizing polyresistance into the DR-TB group. This step is still not in accordance with the low success rate of DR-TB treatment in Indonesia, ranging from 45-50%. The latest DR-TB management recommendations by WHO in 2022 have implemented a 6-month treatment regimen to minimize the occurrence of treatment dropout or patient treatment non-compliance. The BPaLM/BPaL regimen is a shorter-duration oral regimen that is expected to help achieve the End TB 2015-2030 targets. Previously used short-term regimens have now been modified with Ethionamide and Linezolid variants as alternatives for DR-TB management if the BPaLM/BPaL regimen does not meet the criteria for use.
Intervention Model for Pulmonary Tuberculosis (TB) with A Positive Acid-Fast Bacilli (AFB+) in Peukan Bada Sub-district, Aceh Besar Regency Farrah Fahdhienie; Wardiati, Wardiati
Indonesian Journal of Tropical and Infectious Disease Vol. 13 No. 2 (2025)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v13i2.62967

Abstract

Pulmonary tuberculosis (TB) with positive Acid-Fast Bacilli (AFB+) remains one of the most transmissible infectious diseases worldwide. This disease poses a significant public health challenge in many countries. This study aimed to develop a risk-factor-based intervention model to reduce the incidence of Pulmonary TB (AFB+). A case-control approach was employed, with the case group comprising people diagnosed with Pulmonary TB (AFB+), and the control group consisting of non-TB individuals from the same neighborhoods. Binary logistic regression was used for bivariate analysis, and multivariate analysis utilized logistic regression. This study found that the social determinants model accounted for 34.9% of the variance in the incidence of Pulmonary TB (AFB+) (R² = 0.349). The biological determinants model showed an R² of 0.127, indicating that this model explains 12.7% of the variance in the disease. The third model, which focused on behavioral determinants, had an R² of 0.312, meaning that behavioral factors accounted for 31.2% of the variance. The fourth model, examining the physical condition of housing, showed an R² of 0.425, indicating that 42.5% of the variance in Pulmonary TB (AFB+) is explained by variables related to housing conditions. In conclusion, the physical condition of housing emerged as the strongest predictor of Pulmonary TB (AFB+). These findings suggest that improving housing conditions should be a key component of public health strategies to reduce the incidence of Pulmonary TB (AFB+). Targeted interventions to improve the household environment are crucial for reducing the risk and transmission of Pulmonary TB (AFB+).
Effect of Fetal Bovine Serum Concentration on Detection and Morphological Identification of Blastocystis hominis in vitro Janendra, Putu Sathiya Adi; Sukarma, Kadek Edy; Sarita, Kadek intan Arta; Maheswari, Kadek Indira; Giri, Made Kurnia Widiastuti; Permasutha, Made Bayu; Pasala, Metamalik
Indonesian Journal of Tropical and Infectious Disease Vol. 13 No. 2 (2025)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v13i2.64829

Abstract

Diarrhea significantly contributes to the high rates of illness and death among young children. Diarrhea can be caused by bacterial infections, viruses, or even parasites. Blastocystis hominis causes parasitic diarrhea, which can be identified by microscopy, culture, and molecular methods. Previous reports have modified the Jones’ culture medium using three different serums, such as human plasma, donkey serum, and horse serum (in Jones’ medium). This research replaces horse serum with fetal bovine serum for detection tests, morphological observation, and diagnosis of B. hominis. The research encompasses five experimental groups, each subjected to varying concentrations of fetal bovine serum: 2%, 10%, 20%, 30%, and 40%. Detection analysis is conducted using the Mc-Nemar test, while the Wilcoxon test is applied to evaluate ordinal data from morphological assessments. Diagnostic tests and metrics such as accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) are performed using MedCalc® software. The findings demonstrate that serum concentrations of 2%, 10%, 20%, and 30% produced effective results in detection tests, morphological identification, and diagnostic evaluations of B. hominis, exhibiting high sensitivity, specificity, PPV, NPV, and accuracy. Fetal bovine serum can be used at a concentration of 2% in a Jones’ medium that has been modified. This depends on the results of detection tests, morphology, and diagnosis.
Resistance Pattern of Anti-TB Drugs in Drug-Resistant TB of Pulmonary Tuberculosis Patients in Dr. Soetomo Academic Hospital, Surabaya, Indonesia Marsha Maritsa, Olivia; Mertaniasih, Ni Made; Permatasari, Ariani; Kusmiati, Tutik
Indonesian Journal of Tropical and Infectious Disease Vol. 13 No. 2 (2025)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v13i2.66525

Abstract

Pulmonary tuberculosis is an infectious disease that can be transmitted through the air due to infection with Mycobacterium tuberculosis bacteria. According to the WHO, TB is the second-highest cause of death in infectious diseases in the world. This study aims to determine patterns of anti-TB drug resistance in drugresistant TB patients in Dr. Soetomo Academic Hospital from January 2022 to December 2023. This was a descriptive retrospective using patient medical record data in Dr. Soetomo Academic Hospital for the period January 2022 - December 2023. This study included 261 drug resistant pulmonary TB patients, the majority of whom were new TB patients (61.3%). Anti-TB drug resistancewas most prevalent in RR-TB (43.7%), with the highest number of new cases (28.4%). Drug susceptibility test showed High-dose Isoniazid (INHHD) had a high resistance rate (56%). Isoniazid (H) had a high resistance rate (66%). Pyrazinamide (Z) showed high sensitivity (66%). Levofloxacin (Lfx) showed high sensitivity (89%). High-dose Moxifloxacin (MfxHD) high sensitivity level (94%). Moxifloxacin (Mfx) high sensitivity level (92%). Bedaquiline (Bdq) high sensitivity level (98%). Linezolid (Lzd) high sensitivity level (99%). Clofazimine (Cfz) high sensitivity level (97%). Amikacin (Amk) high sensitivity level (100%). Drug-resistant pulmonary TB patients recently show a high drug sensitivity pattern to the second-line anti-TB drugs. MTB has become resistant to Isoniazid. However, it is still sensitive to Pyrazinamide by 66% and Levofloxacin by 89%. Moxifloxacin, Bedaquilin, Linezolid, Clofazimine, and Amikacin have high sensitivity >90%.
Synthesis and Characterization of Cu(II)-EDTA Complexes: Antibacterial Studies (Escherichia coli, Staphylococcus aureus) and Inhibition of Dengue Virus Serotype 2 in Vero Cell Kinetasari, Theresia Janice; Sucipto, Teguh Hari; Nugroho, Browi; Hariyono, Hariyono; Rehman, Saifur
Indonesian Journal of Tropical and Infectious Disease Vol. 13 No. 2 (2025)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v13i2.69005

Abstract

The Cu(II)-EDTA complex is known to have antibacterial and antiviral potential, but its effectiveness against pathogenic bacteria and dengue virus serotype 2 (DENV-2) still needs to be studied. This study synthesized and characterized the Cu(II)-EDTA complex of CuSO4 precursors, and then tested the antibacterial activity against Escherichia coli and Staphylococcus aureus, as well as the antiviral activity against DENV-2 in Vero cells. This study successfully synthesized and characterized the Cu(II)-EDTA complex using CuSO4 as a precursor through the solvothermal method, producing blue crystals with a Cu ratio of 1:1. DSC analysis showed thermal stability up to 250°C with an endothermal peak at 270-300°C. The particles are 6.31 nm in size with a PDI of 0.076, indicating uniform distribution with nanoparticle size (<100 nm). FTIR confirms the formation of the complex through significant shifts in the O-H and C=O bands. SEM shows a layered morphology that can affect the solubility and release of substances. UV-Vis shows maximum absorbance peaks of EDTA at 244 nm and CuSO4 at 740 nm. Antibacterial tests of Cu(II)-EDTA against E. coli and S. aureus showed that Cu(II)-EDTA had less activity than pure CuSO4. For DENV-2, CuSO4 was more effective with an EC50 value of 77.86 μg/mL, lower than Cu(II)-EDTA 356.13 μg/mL, indicating that CuSO4 was better at inhibiting viral replication.

Page 1 of 1 | Total Record : 8

 1 

Filter by Year

2025 2025


Reset
Filter By Issues
All Issue Vol. 13 No. 2 (2025) Vol. 13 No. 1 (2025) Vol. 12 No. 3 (2024) Vol. 12 No. 2 (2024) Vol. 12 No. 1 (2024) Vol. 11 No. 3 (2023) Vol. 11 No. 2 (2023) Vol. 11 No. 1 (2023) Vol. 10 No. 3 (2022) Vol. 10 No. 2 (2022) Vol. 10 No. 1 (2022) Vol. 9 No. 3 (2021) Vol. 9 No. 2 (2021) Vol. 9 No. 1 (2021) Vol. 8 No. 3 (2020) Vol. 8 No. 2 (2020) Vol. 8 No. 1 (2020) Vol. 7 No. 6 (2019) Vol. 7 No. 5 (2019) Vol. 7 No. 4 (2019) Vol. 7 No. 3 (2018) Vol. 7 No. 2 (2018) Vol. 7 No. 1 (2018) Vol. 6 No. 6 (2017) Vol. 6 No. 5 (2017) Vol. 6 No. 4 (2017) Vol. 6 No. 3 (2016) Vol. 6 No. 2 (2016) Vol. 6 No. 1 (2016) Vol 5, No 7 (2015) Vol. 5 No. 6 (2015) Vol 5, No 6 (2015) Vol 5, No 5 (2015) Vol. 5 No. 5 (2015) Vol. 5 No. 4 (2015) Vol 5, No 3 (2014) Vol. 5 No. 3 (2014) Vol 5, No 2 (2014) Vol. 5 No. 2 (2014) Vol 5, No 1 (2014) Vol. 5 No. 1 (2014) Vol 4, No 4 (2013) Vol. 4 No. 4 (2013) Vol 3, No 2 (2012) Vol. 3 No. 2 (2012) Vol. 3 No. 1 (2012) Vol 3, No 1 (2012) Vol. 2 No. 1 (2011) Vol 2, No 1 (2011) Vol. 1 No. 3 (2010) Vol. 1 No. 2 (2010) Vol. 1 No. 1 (2010) Vol 1, No 1 (2010) More Issue