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WMJ (Warmadewa Medical Journal)
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Published by Universitas Warmadewa
ISSN : 25274627     EISSN : 25799010     DOI : doi.org/10.22225/wmj
Core Subject : Health,
Health Professions Medicine & Pharmacology
WMJ (Warmadewa Medical Journal) is the Journal of Medicine & Health, contains scientific articles (Original/ Research Articles, Review Articles, Case Reports) by academic community of the Faculty of Medicine and Health Sciences Warmadewa University, other Faculties of Medicine and Health Sciences and other related Institutions. It is the medium for hardskill and softskills development as an integral part of the Tri Dharma Perguruan Tinggi (Education, Research, Public Service) and health services in the forms of media of communication, information, scientific education, as a subsystem of Medicine and Health holistic and comprehensive services.
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Articles 104 Documents
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Exercise and Sports Activities in Patients with Heart Failure Sidhi Laksono; Hillary Kusharsasmita
WMJ (Warmadewa Medical Journal) Vol 7 No 1 (2022): May 2022
Publisher : Warmadewa University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmj.7.1.3954.13-22

Abstract

Exercise training is an essential additional non-pharmacological method to treat heart failure patients that has been shown to have significant impacts on mortality, morbidity, exercise capacity and quality of life. Various type of training are developed to resolve the needs of heart failure patients, including those who want to participate in sport activities. It is critical and challenging to prescribe personalized exercise training program perfectly, therefore, this review provides brief overview of the advantages and recommendations to prescribe individualized type of exercise training including aerobic, resistance, respiratory, aquatic and competitive sport activities for patients with heart failure. A comprehensive electronic search was conducted using PubMed, Google Scholar, and ScienceDirect. The search was limited to English-language publications from 2004 to 2021. Hand searching of relevant journals and reference lists was also performed. Exercise training should be component of a comprehensive heart failure care approach. Each patient with heart failure may have a different endurance to tolerate the same relative training. Individualized exercise training combined with a preliminary examination improves disability while also decreasing morbidity and mortality Keywords: heart failure, nonpharmacological management, sport exercise
The Effect of Type II DM on the Incidence of Sensorineural Deafness at Bali Royal General Hospital Agus Santosa; I Wayan Sulistiawan
WMJ (Warmadewa Medical Journal) Vol 7 No 1 (2022): May 2022
Publisher : Warmadewa University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmj.7.1.4147.1-12

Abstract

Type II diabetes mellitus (DMT II) is a major health threat, and DM is known to be associated with sensorineural deafness. Age, duration of DM, hypertension and hypertriglycerides are believed to influence this process. This study aims to determine the relationship between type II DM and the incidence of sensorineural hearing loss at Bali Royal General Hospital. The study used a case control design which was carried out on patients admitted between July-September 2021 at Bali Royal General Hospital. The sampling technique employed in the DMT II group with sensorineural deafness was total random sampling, while for comparison, simple random sampling was used. The analyses were carried out by descriptive analysis, chi square test for bivariate data, and logistic regression test for multivariate analysis. The p value is said to be meaningful if <0.05. The whole process of data analysis in this study used SPSS.sav 25. The number of samples was 8 patients with an average age of 49.62 ± 8.45. The mean of RBS (Random Blood Sugar) sugar was 152.25±60.92 mg/dL, and FBS (Fasting Blood Sugar) was 87.87±14.09 mg/dL. Patients with low FBS values ​​and diabetes duration of <5 years had more normal hearing conditions in the right ear (60%), while patients with high FBS and diabetes duration of ≥5 years had more SNHL (66.7%). However, the two conditions did not show a statistically significant relationship (p>0.05). The results of multivariate analysis found that there was no significant relationship between FBS levels and age with hearing conditions in the left ear (p> 0.05). In this study, there was no significant relationship between FBS, duration of DM, pattern of drug consumption, age, and hypertension status of DM patients with the incidence of SNHL in the right and left ears. Keywords: Type II diabetes mellitus, sensorineural deafness, hearing loss
In Vitro Study: Antimalarial Activity of Rivet Sea Cucumber Extract (Holothuria atra) With Ethyl Acetate Solvent Against Plasmodium falciparum : none Prawesty Diah Utami; Zuhro Putri Febrianti Febrianti
WMJ (Warmadewa Medical Journal) Vol 7 No 1 (2022): May 2022
Publisher : Warmadewa University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmj.7.1.4287.23-32

Abstract

Abstract Indonesia is experiencing a decreased cure rate of malaria caused by the species Plasmodium falciparum. Alternative medicine, in this case, uses marine biota, namely lollyfish (Holothuria atra), which has a lot of active compound content; the purpose uses the biota because many reports that there is a failure of malaria treatment therapy due to Artemisinin-based Combination Therapy (ACT) resistance. The purpose of this study was to find out the antimalarial activity of Holothuria atra extract with ethyl acetate solvent at dose 0.01; 0.1; 1; 10; and 100 Ug/ml against Plasmodium falciparum in vitro. Extract lollyfish using the maceration method. The lollyfish powder will be dissolved with ethyl acetate solvent for 24 hours. Antimalarial activity testing is measured through 4 parameters, namely the measurement of parasitemia rates, % parasite growth, % inhibitory rate, and IC50. Antimalarial activity with ethyl acetate solvent belongs to a very active category with an IC50 value of 1.52 µg/mL. These results can kill the P. falciparum parasite with a percentage that reaches 0%. A decrease in the percentage of growth occurs when the dose given is too low so that the parasite can grow and survive. The result of higher concentrations of extracts will have a higher percentage of resistance to the growth of parasites. The potential for antimalarial activity in lollyfish extract is influenced by the presence of active content such as alkaloids, flavonoids, catechins, and pyrogallol owned by marine biota animals. This study suggests that lollyfish (H. atra) can be developed as an alternative treatment for malaria. Keywords: Holothuria atra, antimalarial, Plasmodium falciparum, in vitro
Comparison of Push-Up Exercise Methods on Push-Up Test Ability in Medical Students at Warmadewa University Tanjung Subrata; Ni Wayan Rusni; I Nyoman Arie Purwana
WMJ (Warmadewa Medical Journal) Vol 7 No 1 (2022): May 2022
Publisher : Warmadewa University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmj.7.1.4605.40-46

Abstract

TBM members require muscle endurance to implement their tasks, particularly while performing cardiopulmonary resuscitation (CPR), which requires chest, shoulder, and upper arm muscle endurance. Push up is a type of muscle endurance training for the chest, shoulders, and upper arms that do not require any particular equipment or skills. Therefore, the Push Up Test is required for TBM members, and the results suggest that 62% of 2020 TBM members' abilities are below average. The study was conducted on members of the Warmadewa University FKIK Medical Assistance Team to compare the Push Up workout regiments with the same concentric and eccentric phase tempo (P1) and a slower eccentric phase tempo (P2). The two methods are compared to determine which method is more effective in increasing Push Up Test ability. A total of 46 TBM members were involved in this study. The data was analyzed using the paired t-test to compare muscle endurance before and after the exercise was performed. The push up test used during the screening revealed a decrease in muscle endurance fitness, with of students having normal abilities the previous year, but only 16.4 percent in 2021. The exercise intervention 38% had a significant effect on the push up score, which increased by 4.7 points for male after the intervention, while the push up scores for women increased by 5.6 points (95% CI, 3.32 - 8.01). The results revealed that P2 intervention had a greater influence on changes in push-up scores than P1 intervention (mean change was 5.7 for males and 7.3 for females; mean change was 3.8 for males and 4.0 for females; respectfully). This difference, however, was not statistically significant. It can be concluded that push up training improved push up test ability significantly, whereas the comparison of training methods between P1 and P2 was not significantly different. Keywords: muscle endurance, push up method, push up test
Faktor yang Berhubungan dengan Long-term COVID-19: Studi Observasi Cross-Sectional di Indonesia Arina Dery Puspitasari; Nanda Ardianto; Lily Aina; Eunice Marlene Sicilia Kundiman; Fatimatuz Zahra Oviary Satryo; Melinda Putri Amelia Rachman; Fauzul Meiliani; Pharmasinta Putri Hapsari; Bambang Subakti Zulkarnain; Alfian Nur Rosyid; Tamara Nur Budiarti; Brigitta Dhyah Kunthi Wardhani
WMJ (Warmadewa Medical Journal) Vol 7 No 1 (2022): May 2022
Publisher : Warmadewa University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmj.7.1.4784.33-39

Abstract

Long-term COVID-19 could occur in COVID-19 patients, affecting the patient's quality of life, and becoming a problem for public health. However, information is rarely on factors associated with the occurrence of long COVID-19 cases. This study analyzed factors associated with long-term COVID-19. The study was an observational cross-sectional, conducted in August 2021. The data were collected through a Google form questionnaire distributed to COVID-19 survivors in Indonesian. They must be aged more than 17 years to meet the inclusion criteria, while those with incomplete data were excluded. The data were processed by using SPSS 21 with an ordinal regression test in which an alpha level was 5%. As many as 101 from 16 men (15.8%) and 85 women (84.2%) were obtained. Comorbid status (p-value = 0.001) and duration of treatment (p-value = 0.034 and 0.015) had a significant association with the occurrence of long-term COVID-19. Meanwhile, age, gender, occupation, type of care, and vaccination status were not likely associated with long-term COVID-19. COVID-19 patients with comorbidity and a long duration of treatment are more likely to experience long-term COVID-19. Keywords: COVID-19, long-term COVID-19, factor, public health
Specific Histologic Type of Leiomyoma Related to Estrogen Receptor Expression Ni Wayan Armerinayanti; Desak Putu Oki Lestari; I Gde Sastra Winata
WMJ (Warmadewa Medical Journal) Vol 7 No 2 (2022): November 2022
Publisher : Warmadewa University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmj.7.2.4601.55-59

Abstract

Uterine Leiomyoma or fibroid is the most common gynecologic benign neoplasm which arising from monoclonal proliferation of smooth muscle cells in uterine wall. Some specific types of uterine leiomyoma, such ascellular leiomyoma, symplastic leiomyoma, mitotically active leiomyoma andmyxoid leiomyomahave different histomorphology from usual type leiomyoma. It also have wide variety of tumors size, but this study found that no correlation between type of leiomyoma and its size. Additional non-invasive therapy that predominantly developed in leiomyoma include many antagonist agents of estrogenic receptor. So, important to determine of estrogen receptor activity before that hormonal therapy prescription.Histopathology parameter that predict estrogen receptor activity in leiomyoma was not well understood. This study also try to correlate between specific histologic type of leiomyoma and estrogen receptor activity. This study was a retrospective crossectional study which analized by pearson chi-square test with p value < 0.05 and CI 95%. Result: There was significant correlation between specific histologic type of leiomyoma and estrogen receptor expression (p=0.007; p<0.05). Key Words: Leiomyoma, Estrogen Receptor
Analysis of Factors Affecting Healing of Acute Pharyngitis Viral Patients in Puskesmas I, Klungkung-Bali Ida Ayu Manik Partha Sutema; Made Sudiari; I Gede Palguna Reganata
WMJ (Warmadewa Medical Journal) Vol 7 No 2 (2022): November 2022
Publisher : Warmadewa University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmj.7.2.4753.60-69

Abstract

Abstract Antibiotic resistance is closely related to the inappropriate use of antibiotics, namely the indication, dose, frequency, and duration of use. Permenkes No. 5 of 2014 states that acute pharyngitis is given antibiotic therapy if it meets the diagnostic criteria using the center criteria, but this criterion is difficult to apply because doctors take longer to diagnose. Previous research at the Klungkung I Primary Health Center used diagnosis utilizing a swab test. It was found that 100% of bacterial pharyngitis patients were negative. The strategy of delaying antibiotics for 3 days can prevent antibiotic resistance, but in therapy, without antibiotics, it is important to increase the effectiveness of therapy, it is deemed necessary by the researchers to conduct a study to analyze the factors that affect the recovery of patients with acute pharyngitis, which are mainly caused by viruses. Analyzing the factors that affect the recovery of viral pharyngitis patients. The design of the cross-sectional study was through observation of the medical record data of patients who came to the Klungkung Primary Health Center I for 3 months and got diagnostic facilities using the swab test. Patients who got a negative swab test were analyzed for the factors that influenced their recovery. Anti-inflammatory variables, rest, and paracetamol significantly affected the recovery of acute pharyngitis patients (p <0.05), and the importance index in CART analysis found that paracetamol was the most influential, followed by rest, administration of vitamins, and anti-inflammatory. Antibiotics, anti-allergies, and cough medicines do not affect the recovery of patients with acute pharyngitis viral. Paracetamol has the most effect on patient recovery, followed by rest and administration of vitamins, anti-inflammatory has very little effect on the recovery in patients of acute pharyngitis viral. Keywords: acute pharyngitis, cure, CART.
Protective Effect of Nigella sativa Seed Extract on Alloxan-Induced Mice Kidney Histology Hotimah Salim; Evi Sylvia Awwalia; Ilham Putera Alam
WMJ (Warmadewa Medical Journal) Vol 7 No 2 (2022): November 2022
Publisher : Warmadewa University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmj.7.2.4768.70-73

Abstract

Abstract Nigella sativa (N. sativa) has been used in traditional medicine, and several studies have been performed in the last decades to reveal its effects of it on different medical disorders such as diabetes, dyslipidemia, hypertension, and obesity. This study aimed to evaluate the effects of Nigella sativa extract in an alloxan-induced mice model. This research was a true experimental post-test-only control group design. Eight-weeks old male Mus musculus were treated with alloxan (150 mg/ kg) by a single intraperitoneal injection to induce diabetes mellitus. At three days of injection, N. sativa extract (150 and 300 mg/kg) was administered via gavage for two weeks. The result of this study showed that N. sativa seed extract had a significant (P<0.05) nephroprotective effect on the kidneys based on the degree of kidney damage in alloxan-induced mice. This effect may be due to Nigella sativa’s antioxidant properties. Keywords: Nigella sativa, histology kidney, oxidative stress
Community Survey on Blood Pressure and Levels of Blood Glucose, Cholesterol and Uric Acid Among People 45 Years and Above in Rural Villages of Bali Putu Sutisna (Scopus ID: 6506044199); I Ketut Tangking Widarsa; I Wayan Darwata; I Nengah Kapti
WMJ (Warmadewa Medical Journal) Vol 7 No 2 (2022): November 2022
Publisher : Warmadewa University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmj.7.2.4903.47-54

Abstract

OBJECTIVE. To observe the proportion of high blood pressure and high blood glucose, cholesterol and uric acid among people aged 45 years and older at the rural villages of Pejeng, Samplangan and Petak, in Gianyar Regency, Bali. METHODS. The survey’s samples were all persons aged 45 years and over who came voluntarily to participate in the survey. Blood pressure was measured by mercury sphygmomanometer (Nova). Non-fasting levels of serum glucose, cholesterol, and uric acid were assessed by rapid test method using Easy Touch CGU apparatus. Each parameter studied was categorized as “high” and “normal” (blood pressure high: ≥140/90 mmHg; blood cholesterol high: ≥200mg/dl; blood glucose high ≥200mg/dl; blood uric acid high: >7.0 mg/dl, while other measurements below those values were categorized as normal. Data were analyzed descriptively and presented in tables of frequencies. RESULTS. A total of 650 people aged 45 years and above participated in the survey (Samplangan village: 157 people, Pejeng village: 168 people, Petak village: 225 people). Of 650 study subjects examined, 43.8% had high serum cholesterol, 22.8% had high blood pressure, 26.3% had high serum uric acid, and 9.8% had high blood glucose. According to gender, 49.5% males and 38.2% females had high blood cholesterol, 27.3% males and 20.5% females had high blood pressure, 38.4% males and 20.3% females had high blood uric acid, and 11.1% males and 9.4% females had high blood glucose, respectively CONCLUSIONS. In respective three villages greatest proportion of the study subjects had high serum cholesterol, followed in order of decreasing proportions by either high blood pressure or high blood uric acid, and the lowest proportion was with high blood glucose.
Mesenteric Ischemia: Diagnosis and Management Sidhi Laksono; Natasha Anindhia Harsas
WMJ (Warmadewa Medical Journal) Vol 7 No 2 (2022): November 2022
Publisher : Warmadewa University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmj.7.2.5112.83-90

Abstract

Abstract Mesenteric ischemia is a rare etiology of abdominal pain caused by impaired blood flow to the mesenteric circulation. This condition has acute and chronic variations and is associated with high mortality and morbidity. Early diagnosis is needed to determine management and prevention efforts towards a worse prognosis. The main principles of management of mesenteric ischemia are the restoration of bowel perfusion and resection of the necrotic bowel. This review will discuss the basic materials, diagnosis, and patient management strategies based on the conditions and causes of mesenteric ischemia. Keywords: mesenteric ischemia, necrosis, thrombosis, embolism

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