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INDONESIA
Journal of Agromedicine and Medical Sciences
Published by Universitas Jember
ISSN : 24609048     EISSN : 27145654     DOI : -
Core Subject : Health,
Jurnal Agromedicine and Medical Sciences (AMS) adalah jurnal berkala empat bulan (Februari, Juni dan Oktober) yang berisi berbagai artikel dalam bentuk penelitian, tinjauan sistematis dan laporan kasus dalam bidang kedokteran dengan fokus pada ilmu-ilmu kedokteran dasar, kedokteran klinis dan agromedis.
Arjuna Subject : -
Articles 305 Documents
Combination of Body Acupuncture with Scalp and Ear Microacupuncture in Treating Alzheimer's Dementia in Elderly, A Case Report fitriani, Elies; Roosheroe, Arya Govinda; Nareswari, Irma; Viventius, Yoshua; Srilestari, Adiningsih
Journal of Agromedicine and Medical Sciences Vol 10 No 3 (2024)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v10i3.48503

Abstract

Dementia refers to impairment in more than one domain of cognitive function. The most common cause of dementia is Alzheimer's dementia (AD). AD is associated with the influence of amyloid, oxidative stress, as well as abnormal phosphorylation of the protein Tau which forms neurofibrillary plaques in neurons. Clinical symptoms include progressive memory impairment for current events, cognitive impairment, general confusion, agitation, delusions, social disinhibition, and paranoia. A 68 year old man complained of rapid forgetfulness and decreased cognitive function accompanied by insomnia. Acupuncture manual therapy was performed at points GB20, LI4, HT7, KI3 bilaterally and EX-HN1, EX-HN3, GV20, CV9, CV4, CV3. Combine with scalp acupuncture Zhu Scalp Head and Face, as well as bilateral anterior hypothalamus and master cerebral ear points. Electroacupuncture 2 Hz continuous wave electroacupuncture at points ST25-ST28, CV12-CV6, and ST36-SP6. Therapy is carried out 2 times a week. Evaluation using MMSE ad PSQI. After 10 treatments, there was improvement in clinical symptoms, MMSE and PSQI scores. Manual acupuncture and electroacupuncture, a combination of body points, scalp and ear microcupuncture are useful in the management of Alzheimer's dementia accompanied by insomnia as non-pharmacological adjuvant therapy with positive results. Keywords: Manual acupuncture, electroacupuncture, scalp microacupuncture, ear microacupuncture, Alzheimer's dementia
The Relationship of Work Duration and The Symptom of Carpal Tunnel Syndrome (CTS) in Rujak Sellers in Glenmore District Banyuwangi Regency Syafira, Syafira; Purwandhono, Azham; Handoko, Adelia
Journal of Agromedicine and Medical Sciences Vol 10 No 3 (2024)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v10i3.49649

Abstract

Carpal Tunnel Syndrome (CTS) is a neuromuscular disease characterized by tingling, pain and sensory disturbances in the palms and fingers due to compression of the median nerve which is in the carpal tunnel. One of the risk factors for CTS is that repetaed wrist flexion-extension movements over a long period of time can trigger mechanical trauma or ischemia to the median nerve. Rujak seller is one of the jobs that is at risk of experiencing CTS. This research was conducted to determine the relationship between duration and frequency of work and symptoms and severity of CTS in rujak sellers in Glenmore District, Banyuwangi Regency. This cross-sectional analytical observational study was conducted from April to June 2024 and involved 59 respondents. Data was collected through interviews using questionnaires on work duration, work frequency, CTS symptoms and the Indonesian version of the Boston Carpal Tunnel Syndrome Questionnaire (BCTQ). The results of the Spearman analysis show a significant relationship between work duration and CTS symptoms (p=0.005) with a correlation coefficient of 0.361. The results of data analysis also show a significant relationship between work frequency and CTS symptoms (p=0.000) with a correlation coefficient of 0.595. This research concluded that the duration and frequency of work had a significant positive relationship with the symptoms and severity of CTS. The longer the duration of work and the more frequent the frequency of work, it can increase the risk of CTS and increase the severity of CTS. Keywords: Carpal Tunnel Syndrome; CTS Symptoms; Duration of Work; Frequency of Work
Risk Factor Analysis of Residential Topography and Age on Prostate Cancer Incidence Nabilah, Aisyah; Kurniati, Yuni Prastyo
Journal of Agromedicine and Medical Sciences Vol 10 No 3 (2024)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v10i3.52261

Abstract

Prostate cancer is malignancy that originates from the luminal and basal epithelial acinar of prostate gland. Global Cancer Statistics in 2020 stated that prostate cancer is the third most common type of cancer in the world. The incidence and mortality of prostate cancer in Indonesia ranks 10th out of 32 Asian countries. Prostate cancer is multifactorial disease influenced by genetic mutations and inflammation. Research shows risk factors include increasing age and topographical factors of residence. Literature studies from various sources related to age and topography of residence in prostate cancer are still very limited. This study aims to analyze the effect of topographic profile factors of rice fields around the residence and age on the severity of prostate cancer An Observational analytic study was conducted with a case control design. Total of 177 samples using total sampling method. Age variable parameters are less than or more than 65 years. While the topography of residence uses a cut-off point of 39%. The results of the chi-square test found a significant influence between topographic profile of rice fields around the residence with prostate cancer incidence (p = 0.028, OR = 2.155). The results also found a significant influence between age factor with prostate cancer incidence (p=0.018, OR=2.187). The incidence of prostate cancer caused by the topographic profile of residence and age amounted to 7.2%. In conclusion shows that the topographic profile of the rice field area around the residence and age have a significant influence on prostate cancer severity. Keywords: age, pollutant, prostate cancer, residence, rice field
Allergic Contact Dermatitis with Underlying Disease Seborrhoeic Dermatitis: A Case Report Miranti, Umi; Yoga, R. Ristianto; Nuridah, Ayu Lilyana; Amien, M. Irsyad; Misturiansyah, Nurrul Izza
Journal of Agromedicine and Medical Sciences Vol 10 No 3 (2024)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v10i3.48892

Abstract

Seborrhoeic dermatitis is a skin disease with erythropopulosquamous morphology in areas of the skin that are rich in sebaceous glands such as the folds, scalp and face. The prevalence of seborrheic dermatitis worldwide is only around 5%, but the incidence of the non-inflammatory type of this disease (dandruff) reaches 50%. Seborrheic dermatitis can appear together with other types of dermatitis such as contact dermatitis, such as allergic contact dermatitis or irritant contact dermatitis. In this case, we will describe the incidence of seborrheic dermatitis accompanied by allergic contact dermatitis. Diagnosis in cases of seborrheic dermatitis accompanied by contact dermatitis must be carried out appropriately according to the subjective data and efflorescence obtained. The correct diagnosis influences appropriate management and a better prognosis for the patient. Keywords: Seborrhoeic dermatitis, allergic contact dermatitis
Impact of the User-Friendliness of BalitaGrow+ on Compliance with Children's Daily Nutrition Column Completing Pradewi, Ranny Tandria; Marchianti, Ancah C N; Shodikin, Muhammad Ali; Rachmawati, Dwita Aryadina; Kusuma, Irawan Fajar; Sudarmanto, Yohanes
Journal of Agromedicine and Medical Sciences Vol 10 No 3 (2024)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v10i3.46663

Abstract

Abstract Nutritional imbalances can lead to malnutrition which can affect children's physical and cognitive growth and development. Advances in science and technology have created opportunities for innovation in the form of health applications to help monitor children's growth and development, nutritional status, and children's daily nutritional intake. The factor that influences the intention to use technology is the ease of use. This indicates that the easier the application is to use, the higher a person's interest and compliance will be in using the application regularly. This research aims to determine the effect of ease of use of the BalitaGrow+ application on compliance with filling in the daily nutrition column for children in Rambigundam Village, Jember. This research was an analytical observational research with a cross sectional approach with a sample size of 35 people who meet the criteria. Data analysis used univariate tests and bivariate used the Spearman Rank correlation test. The results obtained from 35 respondents showed that 34 people (97.1%) found it easy to use the BalitaGrow+ application and 31 people (88.6%) had good compliance in filling in the child's daily nutrition column in the application. The results of statistical analysis showed a significance value of p value >0.05 (0.726). So it can be concluded that there was an insignificant influence between the ease of use of the BalitaGrow+ application on compliance with filling in the daily nutrition column for children in Rambigundam Village, Jember. It is suggested to increase the sample size and investigate other influenced factors for future study. Keywords: health application, ease of use, compliance of filling, children’s nutrition
Malondialdehyde Expression in HT29 Cells with Blastocystis sp. Exposure Rusjdi, Selfi Renita; Irawati, Nuzulia; Yanwirasti, Yanwirasti; Hilbertina, Noza
Journal of Agromedicine and Medical Sciences Vol. 10 No. 3 (2024)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v10i3.47044

Abstract

Blastocystis sp. is one of the intestinal protozoa that is frequently found in stool specimens of colorectal cancer patients. This protozoan infection will trigger the host cell defense response to produce Reactive Oxygen Species (ROS) which causes oxidative stress. Oxidative stress can cause and aggravate colorectal cancer. Lipid peroxidation is one of the best indicators of ROS levels. Malondialdhyde is its end product so it is used as a marker of oxidative stress. This study aims to determine the exposure of Blastocystis sp. on malondialdehyde expression in colorectal cancer cell line HT29. This research is an experimental study in vitro. HT29 cells were treated with various concentrations of Blastocystis sp. antigen (0.005 μg/ml, 0.01 μg/ml, 0.05 μg/ml, 0.1 μg/ml and 0.5 μg/ml) for 72 hours. Malondialdehyde expression was examined using spectrophotometric method. Data analysis was performed using One Way Anova test. The results of the study are the mean expression of malondialdehyde in nmol/ml. The mean malondialdehyde levels of the control group, treatment with concentrations of 0.005 μg/ml, 0.01 μg/ml, 0.05 μg/ml, 0.1 μg/ml and 0.5 μg/ml were 3.134 nmol/ml, 2.682 nmol/ml, 2.556 nmol/ml, 2.744 nmol/ml, 2.84 nmol/ml and 3.286 nmol/ml respectively. The conclusion is that there is an effect of exposure to Blastocystis sp. on malondialdehyde expression of HT29 cells. Keywords: Blastocystis sp., HT29, malondialdehyde
Computational Insights into Leucaena leucocephala Extract Shampoo as a Malassezia furfur Anti-Dandruff Agent Hibatulloh, Muhammad Farhan; Nafisa, Tsabita; Afnan, Muhammad Syifaul; Andriani, Made Prasanti; Widanto, Cika Abadi Laily; Wisudanti, Desie Dwi
Journal of Agromedicine and Medical Sciences Vol. 11 No. 2 (2025)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v11i2.24051

Abstract

Dandruff is a scalp condition characterized by excessive flaking resulting from colonization by the fungus Malassezia furfur. Chemical-based anti-dandruff shampoos frequently result in side effects, including irritation, resistance, and hair discoloration. This study investigates the efficacy of Leucaena leucocephala leaf extract as a natural treatment for dandruff using an in-silico methodology. This research employed molecular modeling and docking assays targeting the 14-alpha lanosterol demethylase enzyme (CYP51), the primary antifungal target in Malassezia furfur. The docking results indicated that the active compounds in Leucaena leucocephala leaves, namely squalene and lupeol, exhibit a competitive binding affinity for CYP51, similar to the mechanism of action of ketoconazole. Squalene engages in polar interactions akin to the natural ligands of CYP51, whereas lupeol demonstrates robust hydrophobic interactions, suggesting its potential as an enzyme inhibitor. The findings indicate that herbal compounds derived from Leucaena leucocephala may serve as a natural alternative for dandruff treatment, presenting a reduced risk of side effects relative to synthetic chemicals. Further in vivo studies are necessary to validate the effectiveness and safety of anti-dandruff topical formulations. Keywords: CYP51, Dandruff, Leucaena leucocephala, Malassezia furfur, Natural antifungal
Relationship between PLR Value and Severity of Dengue Infection in Pediatric Patients in the Aster Room at RSUD dr. Soebandi Jember Gianevan, Nicholas Jirezra; Riyanti, Rini; Shodikin, Muhammad Ali; Rachmania, Sheilla; Dewi, Rosita
Journal of Agromedicine and Medical Sciences Vol. 11 No. 2 (2025)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v11i2.50026

Abstract

Dengue infection is a disease caused by dengue virus infection and transmitted by the Aedes mosquito, and is a major health problem in children, especially in developing countries. The Platelet to Lymphocyte Ratio (PLR) is a novel inflammatory biomarker that has recently been frequently studied and plays a role in the assessment of viral infectious diseases, and the use of PLR in viral infectious diseases has previously found greater potential compared with the Neutrophil-Lymphocyte Ratio (NLR). It is hoped that PLR can become a new biomarker for predicting the severity of dengue infection which is suitable for use in developing countries because PLR ​​is a cheap biomarker and is available in all clinical conditions. This research is a correlative analytical observational study using a cross-sectional approach. This research design was carried out by collecting data from children diagnosed with dengue infection as well as data on platelets and lymphocytes on the first day of admission to the hospital. This research uses stratified random sampling. Data were analyzed using Spearman correlation with a confidence level of 99%. The results of Spearman's correlation analysis showed a strong significant relationship with p<0.01 (p=0.000) and a correlation coefficient of -0.753. In conclusion, there is a significant and strong relationship between the Platelet-to-Lymphocy Ratio (PLR) value and the severity of dengue infection in pediatric patients in the Aster ward of RSUD Dr. Soebandi Jember. If the PLR ​​value increases, the severity of dengue infection will be lower or decrease and vice versa. Keywords: PLR; dengue infection; children; platelets; lymphocytes
Surgery with Cross-Speciality Approach to Pediatric Gastric Trichobezoar Obstruction In Indonesia: A Case Report Hariono, Hariono; Fardiansyah, Mochamad Syahroni; Ekaputra, Anthony
Journal of Agromedicine and Medical Sciences Vol. 11 No. 1 (2025)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v11i1.51960

Abstract

Trichobezoar, a rare conditions in pediatric patients affecting less than 1%, often associated with trichotillomania, can lead to obstructive symptoms in severe cases. However, none of the published cases have documented surgical intervention alongside interdisciplinary collaboration in Indonesia that comply SCARE 2023. This case report aims to enhance pediatric trichobezoar literature, by sharing tailored approaches for limited-resource settings and the role of multidisciplinary strategies with surgical intervention. We represent a case of an 8-year-old girl from a low resource setting with a recent episode of vomiting after consuming her own hair for the past six months. Esophagogastroduodenoscopy revealed hair bezoar completely occluding the gastric pylorus. The patient underwent laparotomy with gastrotomy to extract the bezoar. She was then treated by the psychiatrist for trichotillomania, by the pediatrics for catch-up growth, and by the dermato-venereologist for alopecia. No complications or adverse events were observed. Keywords: trichobezoar, gastric obstruction, pediatrics, Indonesia, pediatric surgery
Children Under Five Years of Age: Factor Analysis of Tuberculosis Preventive Therapy's Success in Controlling Childhood Tuberculosis Wahyuningsih, dr. Rita; Syafriadi, Mei; Mufida, Diana Chusna
Journal of Agromedicine and Medical Sciences Vol. 11 No. 2 (2025)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v11i2.53703

Abstract

Jember Regency is the 2nd Regency after Surabaya City in finding the highest number of TB cases in East Java Province, with 5,244 adult cases and 478 pediatric TB cases found. Finding TB cases in children is an important component in controlling TB because the number of children aged less than 14 years constitutes 12% of the population. The government's efforts to control childhood TB by providing TPT (TPT) as an effort to strengthen the management of latent tuberculosis infection (ILTB) are still low. Toddlers in close contact with Drug Sensitive Tuberculosis (TB SO) are a group at risk of being infected with TB so they need to get TPT. This study aims to determine and analyze the driving factors, enabling factors, reinforcing factors and the role of the Medication Supervisor (PMO) on medication adherence in the TPT program for toddlers in close contact with TB in Jember Regency. The method in this research uses the Explanatory Research type, which is a type of research that aims to analyze the relationship or influence between variables through hypothesis testing. The results of this research indicate that the success factors of the TPT administration program, namely driving factors, enabling factors, reinforcing factors and the role of the Medication Supervisor (PMO) are proven to influence medication adherence in the TPT administration program for toddlers in close contact. It’s known that the factors contributed mainly to the successness of Tuberculosis Prevention Therapy are family’s support and the rile of the the Medication Supervisor (PMO).