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INDONESIA
ODONTO Dental Journal
Published by Universitas Islam Sultan Agung
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Arjuna Subject : -
Articles 13 Documents
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Search results for , issue "Vol 12, No 3 (2025): December 2025" : 13 Documents clear
Tooth extrinsic stain remover by Averrhoa bilimbi L extract solution Listari, Khusnul Munika; Rudhanton, Rudhanton; Nugraeni, Yuli; Salsabila, Syafira
Odonto : Dental Journal Vol 12, No 3 (2025): December 2025
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.12.3.292-299

Abstract

Background : Dental stains are pigmented deposits that can be a predisposing factor for periodontal disease and caused aesthetic problems. Chromogens from foods and beverages such as coffee can adhere to the tooth surface trough pellicle and forming deposits called tooth extrinsic stains. Averrhoa bilimbi L contains oxalic acid which has potential ability to remove it trough oxidation mechanisms. The aim of this study was to investigate the effectiveness of Averrhoa bilimbi L extract solution on extrinsic tooth stain removal.Method : Tooth extrinsic stain models obtained by soaking the teeth in robusta coffee solution. Twenty-four post extraction premolar teeth with extrinsic stains were divided into 4 groups consisting of control group (immersion in artificial saliva), T1 group(immersion in Averrhoa bilimbi L extract solution 50%), T2 group (immersion in Averrhoa bilimbi L extract solution 75%) and T3 group (immersion in Averrhoa bilimbi L extract solution 100%) for 28 hours. Adobe Photoshop CC 2018 used to evaluate the difference color intensity (ΔE) in CieLAB system before and after the treatment.Result : Anova test showed there’s a significant difference within groups (p<0.05). Post Hoc Posttest showed there are  significant difference of difference color intensity (ΔE) between each group(p<0.05), with the highest average of it on T3 group then followed by T2 group , T1 group and control. Pearson correlation analysis showed there is a positive correlation between concentration and color intensity.Conclusion : Averrhoa bilimbi L. extract solution proven effective as extrinsic stain removal in vitro.
The Potency of miRNA 221-3p as a Molecular Biomarker Of Temporomandibular Disoder: Narrative Review Rintoko, Bimo; Tanti, Ira; Bachtiar, Endang Winiati; Bachtiar, Boy Muchlis; Prihastari, Lisa
Odonto : Dental Journal Vol 12, No 3 (2025): December 2025
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.12.3.241-250

Abstract

United States. The trigeminal nerve might be the source of orof facial pain. Pain can be difficult to diagnose and treat due to the variability of pain complaints. miRNA 221-3p could be a potential biomarker for pain. Genetic polymorphisms and genetic mutations can lead to changes in the activity of inflammatory mediators, sex hormones, matrix-degrading enzymes, and the immune system, which affect bone remodeling homeostasis in the temporomandibular joint.Method: Scientific databases PubMed, Scopus, and Google Scholar were searched for articles published between 2013 and 2023 in order to conduct the study. 168 carefully selected publications providing information on possible biomarkers, particularly miRNA 221-3p, were included in the review of the literatureResult: Genetic polymorphisms and genetic mutations can lead to changes in the activity of inflammatory mediators, sex hormones, matrix-degrading enzymes, and the immune system, which affect bone remodeling homeostasis in the temporomandibular joint. In addition, activity changes were also observed in neurotransmitters and pain receptors, which resulted in relatively high pain sensitivity. Thus, this condition also increases susceptibility to TMD. Genetic analysis and biomarkers of temporomandibular disorders may improve sensitivity and specificity measures in diagnosing and treating patients with TMDConclusion: As a multifactorial disease, genetic factors are risk factors for TMD. Genetic polymorphisms and genetic mutations can lead to changes in the activity of inflammatory mediators, sex hormones, matrix-degrading enzymes, and the immune system, which affect bone remodeling homeostasis in the TMD
Datura metel SEED NANO CHITOSAN EXTRACT GEL’S EFFECT ON ANGIOGENESIS WOUND HEALING OF WISTAR RAT Asriningrum, Vika; Bramanti, Indra; Ardhani, Retno
Odonto : Dental Journal Vol 12, No 3 (2025): December 2025
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.12.3.269-279

Abstract

Background: Datura metel possesses anti-inflammatory properties useful for treating oral mucosal injuries common in children, where healing relies on angiogenesis. Nano chitosan technology addresses herbal bioavailability issues. This study investigated the effect of 1% Datura metel seed nano chitosan extract gel on angiogenesis in Wistar rats. Methods: Eighteen Wistar rats were divided into three groups: 1% Datura metel seed chitosan extract, 1% nano chitosan extract, and a control group. Gels were applied to mandibular gingival wounds with assessments on days 3 and 5. Histological angiogenesis counts were analyzed using two-way ANOVA (p<0.05). Results: Significant differences in angiogenesis counts were found among the chitosan extract, nano chitosan extract, and positive control groups. Furthermore, variations in angiogenesis counts were observed between day 3 and day 5 across all groups. Conclusion: The 1% Datura metel seed chitosan extract gel demonstrated a greater effect in triggering angiogenesis compared to the 1% nano chitosan extract and the positive control.

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