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Fakultas Kedokteran Universitas Mataram Jl. Pendidikan No. 37 Mataram, Nusa Tenggara Barat
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Jurnal Kedokteran
Published by Universitas Mataram
ISSN : 23015977     EISSN : 25277154     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
The Unram Medical Journal managed by the Medical Faculty of Mataram University is a scientific journal to publish the results of the latest research in the field of medical and health related. This journal promote medical sciences generated from basic sciences, clinical, and community research to integrate researches in all aspects of human health. This journal publishes original articles, reviews, and also case reports.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 408 Documents
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Somatostatin Hidayatullah, Rian; Budiawan, Hendra; Darmawan, Budi; Affandi, Erwin
Jurnal Kedokteran Vol 10 No 2 (2021): Jurnal Kedokteran Juni 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i2.482

Abstract

Somatostatin, also known as growth hormone-inhibiting factor (GIF) or somatotropin release-inhibiting factor (SRIF), is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation. Somatostatin can be regarded as secretory pan-inhibitory,because it can inhibit secretion of almost all endocrine and exocrine glands. Somatostatin has 2 active forms (somatostatin-14 and 28), but the short half-life of the hormone was one of the reasons why the native hormone was not feasible for routine clinical practice. Somatostatin analog was synthesized for the first time in 1980-1982 and proved to be more resistant to degradation and more potent than native hormone. There are five somatostatin receptors (SSTR1-5). The genes encoding human SSTR1-5 are located in chromosome 14q13, 17q24, 22q13.1, 20p11.2 and 16p13.3. SSTR expression pattern and complex signaling make somatostatin be such an extraordinary neurotransmitter and hormone. The potent inhibitory action of SSTR on cellular processes such as secretion, proliferation, and apoptosis is the reason for somatostatin to be the target for therapy development. Radiopharmaceuticals used for therapy consist of three parts: somatostatin analog, chelator, and radionuclide (alpha or beta-emitting). Combinations of different peptides, chelators, and radionuclides have been tested in vitro and/or in vivo for their use in peptide receptor radionuclide therapy (PRRT). These compounds are able to irradiate tumors and their metastases via the internalization through a specific receptor subtype which is generally overexpressed on the cell membrane.
HUBUNGAN ANTARA SIKAP TERHADAP PENELITIAN DAN HAMBATAN PENELITIAN DENGAN KETERLIBATAN DALAM PENELITIAN MAHASISWA FAKULTAS KEDOKTERAN UNIVERSITAS MATARAM Puspitasari, Susi; Susani, Yoga Pamungkas; Maulana, Akhada
Jurnal Kedokteran Vol 10 No 2 (2021): Jurnal Kedokteran Juni 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i2.490

Abstract

Background: conducting research is beneficial for the future of a medical doctor, but the medical students in Mataram University have unsatisfactory results in the course of research methodology. Research is also a determinant of the quality of a university. In a medical study, students are required to review or conducting relevant research as the proponent of their professionalism as long life learner. Regarding this study, it aims to measure the relationship of attitude and barriers towards research experiences of students in the medical faculty of Mataram University. Method: this study belonged to a quantitative study with a cross-sectional survey design. The subjects in this study were 129 medical students from a total of 140 of medical students in Mataram University in their 3-year and 4-year study. They have taken a research methodology course as the prerequisite to fill Revised Attitude Towards Research (R-ATR) questionnaire to measure attitude toward research, the questionnaire for both barriers and research experiences. Data from this study were analyzed using Spearman correlation. Results: Attitude toward research and research experience have small and positive correlation (r=0,322;p <0,001), while research barrier is small and negatively correlated towards research experience (r=-0,209;p <0,05). Conclusion: attitudes and barriers can be the factors that affected the frequency of student’s experiences in research.
TERAPI ALBENDAZOLE PADA KASUS CUTANEOUS LARVA MIGRANS (CLM) DENGAN INFEKSI BAKTERI SEKUNDER Suwito, Eva Aguswulandari; Hartati, Farida
Jurnal Kedokteran Vol 10 No 2 (2021): Jurnal Kedokteran Juni 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i2.501

Abstract

Cutaneous Larva Migrans (CLM) is caused by invasion of the hookworm larvae into the skin. In this case, we report a 32 – year- old male patient diagnosed with CLM and secondary bacterial infection. The patient was given oral albendazole 400mg, oral cefixime 100mg, combination oxytetrasiklin and gentamisin topical, combination oral albendazole 400mg with topical betametason valerat 0,1%, and oral cetirizine. The patient showed improvement of the skin lesions after 11 days of therapy.
Efek Hand Hygiene terhadap Dermatitis Tangan Ricky Setiadi Yusuf
Unram Medical Journal Vol 10 No 2 (2021): Jurnal Kedokteran Juni 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i2.505

Abstract

In this pandemic COVID-19 era, it’s important to everyone that maintain cleanliness especially hand sanitation. Hand hygiene behavior is one of many ways that effective to prevent COVID-19. Generally, hand hygiene can be done by two methods, there are hand washing with water and using hand sanitizer. Exaggerating in hand hygiene make a new other health problem, that is hand dermatitis. Nowadays, health care workers are known to have a high risk of developing hand dermatitis due to their work. Based on World Health Organization (WHO), hand washing with water and soap can be done in 40 until 60 seconds, besides, hand washing with hand sanitizer can be done in 20 until 30 seconds. Therefore, prevention of hand dermatitis is important too. Applying moisturizer effectively can reduce the risk of hand dermatitis.
Prospek Media Sel Punca Jaringan Adiposa Terkondisi Sebagai Anti-aging Dirja, Bayu Tirta; Kusuma, Dinie Ramdhani
Jurnal Kedokteran Vol 10 No 2 (2021): Jurnal Kedokteran Juni 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i2.507

Abstract

Abstrak Keluhan kulit keriput dapat terjadi karena proses penuaan yang dapat disebabkan oleh faktor intrinsik dan ekstrinsik akibat paparan ultraviolet (UV). Penelitian kedokteran membuktikan media sel punca jaringan adiposa terkondisi (conditioned medium) mempunyai kandungan beberapa growth factor dan antioksidan, diduga dapat digunakan sebagai terapi anti-aging.
EVALUASI SIFAT FISIK DAN SKRINING FITOKIMIA TEH BIJI PEPAYA (Carica papaya L.) Maulidia Umami; Pratama, Iman Surya; Sriasih, Made
Jurnal Kedokteran Vol 10 No 2 (2021): Jurnal Kedokteran Juni 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i2.522

Abstract

Latar Belakang: Biji pepaya telah digunakan sebagai antelmintik pada ternak. Teh biji pepaya memiliki aktivitas antiparamphistomum secara in vitro melalui metode adult mortality assay. Karakterisasi teh biji pepaya perlu dilakukan untuk menjamin mutu produk teh yang dihasilkan. Penelitian ini bertujuan untuk menentukan karakteristik fisik dan metabolit sekunder teh biji pepaya (Carica papaya L.). Metode: Kandungan senyawa teh biji pepaya dikarakteristisasi melalui skrining fitokimia. Evaluasi fisik teh biji pepaya meliputi organoleptik, pengukuran pH, penentuan bobot jenis, variasi bobot, dan kadar air. Hasil Penelitian: Teh biji pepaya memiliki rasa pahit, aroma khas, dan berwarna kuning bening, dengan pH 5.61, kadar air 6,876%, bobot jenis 1,000431887 g/ml, dan pada variasi bobo tidak ada bobot yang melebihi 12% limit variasi. Teh biji pepaya mengandung flavonoid dan steroid/triterpenoid. Kesimpulan: Teh biji pepaya memenuhi standar mutu teh. Teh biji pepaya mengandung flavonoid dan steroid/triterpenoid.
GAMBARAN EPIDEMIOLOGI KUSTA PADA ANAK DAN PELAKSANAAN KEMOPROFILAKSIS KUSTA DI KOTA MATARAM Affarah, Wahyu Sulistya
Jurnal Kedokteran Vol 10 No 2 (2021): Jurnal Kedokteran Juni 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i2.530

Abstract

Efforts to treat and prevent leprosy have improved, but in fact this disease is still difficult to eliminate and still a world health problem. Leprosy in childhood reflects the on going active transmission of the disease in the community as well as the efficiency of ongoing disease control programs. Effective planning to reduce the incidence of leprosy and its complications in children must be a priority. This cross-sectional study used a mixed of quantitative and qualitative methods. Quantitative data is obtained from secondary data on cases of child leprosy, while qualitative data is obtained from in-depth interviews with the person in charge of the leprosy program at the health center in the city of Mataram. Ms. Excel is used to analyze quantitatively and thematic test is used to analyze qualitatively (open code software). There were two cases of leprosy in children but had completed treatment and cured. The knowledge of the person in charge of the leprosy program about handling leprosy in puskesmas is quite good, but their understanding on the national strategy, especially about chemoprophylaxis is not understood comprehensively. The implementation of the leprosy prevention program at the Puskesmas has been running regularly, however currently constrained by covid-19 pandemic.
Tingkat Pengetahuan Dagusibu Obat Pada Mahasiswa Farmasi Fakultas Kedokteran Universitas Mataram Tahun 2020 Intan Ningtyas Sariasih
Jurnal Kedokteran Vol 10 No 2 (2021): Jurnal Kedokteran Juni 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i2.532

Abstract

Currently, many health problems occur due to the lack of community knowledge and understanding regarding the procedures for using and managing drugs. This led the Indonesian Pharmacists Association (IAI) to design a program called DaGuSiBu (Get-Use-Save-Dispose). This program is vital for the community and pharmacy students as it is related to its future role for drug information service provider. This study aims to determine the knowledge level of DaGuSiBu in pharmacy students in Faculty of Medicine, University of Mataram. This study harnessed the observational research design with a cross sectional approach. It was conducted in the Pharmacy Study Program, Faculty of Medicine, University of Mataram from February to March 2021, with a sample size of 160 pharmacy students class of 2017 to 2020. Data obtained by distributing online questionnaires that have been tested for validity and reliability. In the aspect of getting medicine, the knowledge level of the students are 20% good, 40% sufficient, and 40% less. In the aspect of using medicine, it has a good knowledge level of 42.8%; 14.3% sufficient; and 42.8% less. In the aspect of storing medicine, the knowledge level was only in the sufficient and insufficient categories of 37.5% and 62.5%. Moreover, in the aspect of disposing of drugs, the knowledge level of the respondents was evenly distributed in the three categories with a value of 33.3%. From the results, it can be concluded that the knowledge level of students varies in 4 aspects, getting, using, storing and disposing of drug.
Prolaps Organ Panggul Multipel pada Wanita Multipara: Sebuah Laporan Kasus Triharsadi, Rakhmad; Anggraini, Meilisva Audila; Punarbawa, Gede Made; Danianto, Ario
Jurnal Kedokteran Vol 10 No 2 (2021): Jurnal Kedokteran Juni 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i2.533

Abstract

Prolaps organ panggul (POP) adalah turun atau menonjolnya dinding vagina ke dalam liang vagina atau keluar introitus vagina, yang dapat disertai oleh organ-organ pelvik (uterus, kandung kemih, usus atau rektum). POP menimbulkan rasa ketidaknyamanan (uncomfortable feelings) pada penderitanya, gejala-gejalanya meliputi gejala vagina, buang air kecil (BAK), buang air besar (BAB), dan seksual. Meskipun demikian, POP sering kali tidak terdeteksi pada stadium dini atau bersifat asimtomatik sehingga pasien sering kali berobat pada stadium lanjut. Laporan kasus ini melaporkan seorang perempuan multipara berusia 58 tahun dengan sistokel grade IV, prolaps uteri grade IV, dan rektokel grade IV yang mendapat terapi pembedahan total vaginal hysterectomy dan high levatorplasty.
TINGKAT PENGETAHUAN MAHASISWA PROGRAM STUDI FARMASI FAKULTAS KEDOKTERAN UNIVERSITAS MATARAM TENTANG BEYOND USE DATE OBAT Gita Senja Pertiwi
Jurnal Kedokteran Vol 10 No 2 (2021): Jurnal Kedokteran Juni 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i2.550

Abstract

Latar belakang: Mahasiswa lulusan sarjana farmasi mempunyai pemahaman dan keahlian tentang obat dan penggunaan obat dalam pelayanan kefarmasian. Namun, Istilah (beyond use date) BUD masih jarang diketahui karena masih terbatasnya penelitian. Pemahaman mengenai BUD sangat penting bagi mahasiswa, karena BUD berkaitan dengan stabilitas dan mutu obat. Penelitian ini bertujuan untuk mengetahui tingkat pengetahuan mahasiswa Program Studi Farmasi Fakultas Kedokteran Universitas Mataram tentang BUD obat. Metode: Penelitian ini bersifat observasional dengan desain penelitian cross-sectional yang dilakukan dengan metode survei deskriptif. Penelitian dilakukan pada bulan Mei 2021 dengan jumlah sampel 160 mahasiswa Prodi Farmasi FK UNRAM. Pengambilan sampel dilakukan dengan teknik proportionate stratified random sampling. Data diperoleh dengan menyebarkan kuesioner online yang telah diuji validitas dan reliabilitas. Analisis data dilakukan menggunakan microsoft excel. Hasil: Pada aspek BUD secara umum, tingkat pengetahuan mahasiswa Prodi Farmasi FK UNRAM kategori baik terdapat pada item definisi BUD, expire date dan peran apoteker; kategori cukup pada item perbedaan istilah BUD dan ED; dan item patokan obat berhenti digunakan tergolong kategori kurang. Pada aspek BUD obat racikan, tingkat pengetahuan mahasiswa temasuk kategori baik terdapat pada item peran apoteker dalam BUD racikan dan karakteristik puyer yang tidak bisa digunakan, kategori cukup pada BUD obat racikan semipadat dan kategori kurang pada item menghitung BUD puyer. Kesimpulan: Tingkat pengetahuan mahasiswa Prodi Farmasi FK UNRAM tentang Beyond Use Date obat bervariasi pada aspek BUD obat secara umum dan BUD obat racikan. Kata kunci: tingkat pengetahuan, mahasiswa farmasi, beyond use date, kuesioner, obat racikan

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