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Jurnal Kedokteran
Published by Universitas Mataram
ISSN : 23015977     EISSN : 25277154     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
The Unram Medical Journal managed by the Medical Faculty of Mataram University is a scientific journal to publish the results of the latest research in the field of medical and health related. This journal promote medical sciences generated from basic sciences, clinical, and community research to integrate researches in all aspects of human health. This journal publishes original articles, reviews, and also case reports.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 408 Documents
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A Hemichorea and Hemiplegy as a Clinical Manifestation of Acute Ischemic Stroke Shahab, Fatimah; Hunaifi, Ilsa; Subagiartha, I Wayan
Jurnal Kedokteran Vol 9 No 4 (2020): Jurnal Kedokteran volume 9 no 4 2020
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v9i4.435

Abstract

Hemichorea / hemibalismus (HCHB) and other hyperkinetic movement disorders are a rare presentation of stroke, usually secondary to deep infarctions affecting the basal ganglia and the thalamus. This case report aims to describe patients who experience HCHB as early symptoms of acute stroke infarction accompanied by hyperglycemia. In this case the complaint was accompanied by facial and hypoglossus nerve paresis, and hemiplegic of the contralateral limb of the lesion. Serum glucose and HBA1C levels are elevated. CT scan image shows an infarction in the basal ganglia. The combination of new striatal lesions and hyperglycemia can induce HCHB because both of these can lead to increased inhibition of the subtalamic nucleus and disruption of thalamus GABAergic inhibition. Key words: Hemibalismus, hemichorea, hyperglycemia, ischemic stroke
Subarachnoid Hemorrhage (SAH) Wulandari, Dwi Astuti; Hunaifi, Ilsa; Sampe, Ester
Jurnal Kedokteran Vol 10 No 1 (2021): volume 10 nomor 1 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i1.437

Abstract

Approximately, 10-20% of stroke cases in a year caused by a hemorrhagic strokes. The most dangerous and deadly of hemorrhagic stroke’s is subarachnoid hemorrhage (SAH). SAH have higher impact on economic, morbidity, and mortality than other types of stroke even though the prevalence is quite low. About 80% of non-trauma subarachnoid hemorrhage (SAH) cases are caused by rupture of intracranial aneurysm, which encourages blood to fill the subarachnoid space and stimulates the surrounding structures, it’s cause pathognomonic symptoms of stiff neck and thunderclap headache. Even though there are typical symptoms, misdiagnose of this stroke is still happens. Therefore, a comprehension of all aspects that are related to subarachnoid hemorrhage is very important in optimizing patient ability and service. Keywords: stroke, subarachnoid hemorrhage, intracranial aneurysms
Tanaman Obat Pada Ramuan B2P2TOOT Di Puskesmas Pejeruk Ampenan Kota Mataram Permatasari, Kartika; Aini, Siti Rahmatul; Hanifa, Nisa Isneni
Jurnal Kedokteran Vol 9 No 4 (2020): Jurnal Kedokteran volume 9 no 4 2020
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v9i4.440

Abstract

Latar belakang: Ramuan obat tradisional dari B2P2TOOT adalah ramuan paling banyak yang diresepkan oleh dokter dari 12 provinsi pada tahun 2014. Syarat Fasyankes dapat memberikan pelayanan obat tradisional khususnya ramuan B2P2TOOT adalah memiliki tenaga kesehatan yang telah mengikuti pelatihan saintifikasi jamu. B2P2TOOT terus melakukan evaluasi terhadap ramuan obat yang diberikan dengan memonitoring efek obat dari pelayanan Yankestrad yang menggunakan ramuan B2P2TOOT. Tujuan dari penelitian ini untuk mengetahui komposisi ramuan B2P2TOOT khususnya di Puskesmas Pejeruk Ampenan Kota Mataram yang memberikan pelayanan obat tradisional. Metode: Penelitian ini menggunakan metode kualitatif dengan metode pengambilan data secara cross sectional jenis purposive sampling. Hasil: Terdapat sebanyak 11 ramuan B2P2TOOT di Poli jamu Puskesmas Pejeruk Ampenan. Ramuan B2P2TOOT tersebut dalam bentuk kapsul yang sudah diracik sesuai komposisi tanaman. Komposisi tanaman obat dari tiap-tiap ramuan berbeda, namun secara keseluruhan ramuan tersebut berasal dari tanaman obat yang ada di Indonesia. Spesies tanaman yang dominan digunakan pada 3 atau lebih ramuan B2P2TOOT adalah daun salam (Syzgium polyanthum (Wight) Walp), bunga cengkeh (Syzygium aromaticum), dan temulawak (Curcuma xanthorriza Roxb.). Kesimpulan: Berdasarkan hasil penelitian yang telah dilakukan, maka dapat diambil kesimpulan bahwa komposisi ramuan obat tradisional yang diresepkan di Puskesmas Pejeruk Ampenan Kota Mataram berasal dari tanaman obat Indonesia. Tanaman obat yang paling banyak digunakan dalam ramuan yaitu daun salam, bunga cengkeh dan temulawak yang digunakan pada terapi 3 penyakit atau lebih. Setiap tanaman obat memiliki kandungan metabolit sekunder yang mampu memberikan efek terapi, akan tetapi diperlukan kandungan dari tanaman lain untuk mendukung efek terapi yang diinginkan.
PENGARUH EKSPRESI RESEPTOR INSULIN PANKREAS TERHADAP EKSPRESI GLUT4 NEURON HIPOKAMPUS PADA TIKUS MODEL DIABETES Sahly, Aliza Raudatin; Hunaifi, Ilsa; Lestari, Rizka Vidya; Wardani, Indah Sapta; Padauleng, Novrita; Nurhidayati; Harahap, Herpan Syafii
Jurnal Kedokteran Vol 9 No 4 (2020): Jurnal Kedokteran volume 9 no 4 2020
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v9i4.441

Abstract

Background: Diabetes Melitus (DM) is a degenerative diseases characterized by hyperglycemia condition. Basic Health Research data for 2018, shows an increase in prevalence of DM in Indonesia over last 5 years with 6,9% in 2013 to 8,5% in 2018. Pancreatic insulin receptor expression can be a marker for assessing presence of ? cells, production and secretion of insulin. Insulin could cause GLUT4 to be translocated to cell membrane of hippocampal neurons. In DM conditions, there may be changes in expression of pancreatic insulin receptors accompanied by changes in expression of GLUT4 hippocampal neurons. Methods: This experimental research used 16 white rats (Rattus Novergicus) which divided randomly into 4 groups, namely 2 control grups (A0 and A1) and 2 treatment groups (B0 and B1). Treatment group were induced by diabetes with a single dose of nicotinamide 110 mg/kgBB and streptozotocin 70 mg/kgBB intraperitoneally. The research data were obtained from immunohistochemical analysis of pancreatic and hippocampal tissue. Result: The mean expression of pancreatic insulin receptor in diabetic rat group was higher but not significant on the 14th day observation compared to the 0th day (p>0,05), while the mean GLUT4 expression of hippocampal neurons was significantly higher on 14th day of observation compared to the 0th day (p<0,05). The result of correlation test did not show a significant results in each group both at the 0th and 14th day observation (p>0,05). Conclusion: There was no significant effect of pancreatic insulin receptor expression on hippocampal neuron GLUT4 expression in diabetic model rats.
GAMBARAN DAN KARAKTERISTIK PASIEN DELIRIUM PADA CEDERA OTAK DI RUMAH SAKIT UMUM DAERAH PROVINSI NUSA TENGGARA BARAT Yusuf, Ricky Setiadi; Rohadi; Priyanto, Bambang; Ansyori, Maz Isa
Jurnal Kedokteran Vol 9 No 4 (2020): Jurnal Kedokteran volume 9 no 4 2020
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v9i4.442

Abstract

Latar Belakang: Cedera otak merupakan kejadian trauma yang mengenai otak dan menyebabkan kerusakan baik secara struktur maupun fungsi. Tingginya angka kejadian cedera otak baik di dunia maupun di Indonesia mayoritas diakibatkan oleh kecelakaan lalu lintas kendaraan bermotor. Adanya kerusakan tersebut menyebabkan munculnya sekuele psikiatri dan salah satunya adalah delirium. Metode: Penelitian ini merupakan observasional deskriptif dengan pendekatan cross-sectional. Pengambilan data dilakukan di RSUDP NTB dengan metode nonprobability sampling yaitu consecutive sampling. Cara pengambilan data yaitu secara langsung pada 39 orang pasien cedera otak rawat inap di RSUDP NTB. Peneliti melakukan observasi langsung kepada pasien dan mengkaji rekam medis pasien. Hasil: Dari 39 sampel pasien cedera otak, didapatkan 32 orang (82,05%) mengalami delirium, dengan dominasi pria sebanyak 24 orang (61,54%) mengalami delirium. Berdasarkan derajat keparahannya, didapatkan cedera otak sedang (COS) terbanyak diantara derajat lainnya. Dari hasil CT Scan pasien dengan delirium, kebanyakan pasien memiliki lesi diffuse. Selain itu, hasil laboratorium terhadap kadar leukosit didapatkan meningkat pada pasien delirium, sedangkan kadar glukosa mayoritas pasien dalam batas normal. Kesimpulan: Pasien dengan delirium pada TBI didominasi oleh pria terutama kelompok usia 51-65 tahun. Selain itu, letak lesi yang diffuse, peningkatan kadar leukosit, dan kadar glukosa yang normal sering didapatkan pada pasien delirium pada TBI. Kata kunci: cedera otak, TBI, delirium, jenis kelamin, usia, letak lesi, kadar leukosit, kadar glukosa
PROFIL EFEK SAMPING PENGGUNAAN ANTIRETROVIRAL PADA PENDERITA HIV/AIDS DI POLIKLINIK VCT DI KOTA MATARAM TAHUN 2019 Mitha Yunda Pertiwi; Indah Sapta Wardani; A.A Ayu Niti Wedayani
Jurnal Kedokteran Vol 9 No 4 (2020): Jurnal Kedokteran volume 9 no 4 2020
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v9i4.443

Abstract

Background: In treating HIV infection, Indonesia uses the fast track 90-90-90 approach, which one indicator is giving early ARV treatment to infected patients. First line ARV used in Indonesia today is a fixed-dose combination (FDC) consisting of tenofovir, lamivudine/emtricitabine, and efavirenz. ARV use might cause adverse drug reactions (ADR) with ADR range from mild to severe in HIV patients. This research aims to identify the adverse drug reactions caused by ARV in HIV/AIDS patients in VCT Polyclinic in Mataram City in 2019. Methods: This research is a quantitative descriptive study done in VCT Polyclinic in Mataram city. The subjects are HIV patients in VCT Polyclinic in Mataram city who had met the criteria. This research used secondary data from patients’medical records. Result: Total subjects are 27 patients. ADR occurred in 8 patients (29.6%). These ADR were found in 7 patients using atripla with malaise, dizziness, vomiting, and increased SPOT/SGPT being the most common ADR. One patient using duviral/neviral were found with nausea, vomiting, and itchiness. These ADR came 100% from first degree drug toxicity. Conclusion: The most common ADR were vomiting, malaise, dizziness, and increased SGOT/SGPT. All adverse drug reactions were mild (first degree) therefore therapy was continued and there was no need to consider switching treatment. Keywords: HIV infection, ARV, Atripla, Duviral/Neviral, side effects, first degree
HUBUNGAN ANTARA GAMBARAN HISTOPATOLOGI DENGAN JUMLAH LEUKOSIT PADA PENDERITA LIMFADENITIS TUBERKULOSIS DI NUSA TENGGARA BARAT TAHUN 2019 Alfaridzi, Muhammad; Lestarini, Ima Arum; Djannah, Fathul
Jurnal Kedokteran Vol 10 No 1 (2021): volume 10 nomor 1 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i1.453

Abstract

Background: Indonesia is the 3rd country with the highest incidence of tuberculosis (TB) in the world. 15% of TB cases are EPTB with 50% of them being lymphadenitis TB (LNTB). The histopathological features of the biopsy samples play an important role in the diagnosis of this disease by producing the images of WOG or POG. The number of leukocytes can describe the immune response in people with LNTB. Methods: This study is an observational analytic study with a cross-sectional approach. The data were obtained by documenting the medical records of LNTB patients who were treated at the RSUD Provinsi NTB and RSUD Kota Mataram in the January 2019 - February 2020 period. Results: The total number of research subjects is 51 people. In the histopathological features, 37 samples included WOG, and 14 samples included POG. On the leukocyte count, none of the patients had leukopenia, 39 patients had normal leukocyte counts and 12 patients had leukocytosis. The results of the Spearman correlation test obtained p = 0.005 and r = 0.384 Conclusion: There is a significant correlation between the histopathological features and the number of leukocytes in patients with LNTB in NTB in January 2019 - February 2020. The correlation is weak.
Uji Aktivitas Antiparamphitomiasis Infus Bunga Widuri (Colotropis gigantea) Terhadap Paramphistomum spp. Secara In Vitro Solehah, Kurnia; Damiyati, Siska Yunita; Pratama, Iman Surya; Tresnani, Galuh
Jurnal Kedokteran Vol 9 No 4 (2020): Jurnal Kedokteran volume 9 no 4 2020
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v9i4.454

Abstract

Latar Belakang: Prevalensi paramphistomiasis di provinsi Nusa Tenggara Barat tahun 2014 mencapai 20,7%. Tujuan penelitian untuk membandingkan aktivitas infus bunga Widuri berbagai konsentrasi terhadap Paramphistomum spp. secara in vitro terhadap Albendazol 10% b/v. Metode: Paramphistomum dewasa dikelompokkan ke dalam 5 kelompok : kontrol negatif (larutan NaCl 0,9% b/v), kontrol positif (Albendazol 10% b/v), dan infus bunga Widuri (5, 20 dan 40% b/v). Tiap kelompok diinkubasi pada suhu 37oC, kemudian diamati waktu kematian setiap 15 menit selama 5 jam. Persentase mortalitas ditentukan dan dianalisis secara statistik dengan parametrik dan non-parametrik menggunakan perangkat lunak SPSS v.16; Hasil: Rerata waktu kematian untuk tiap kelompok berturut-turut 270; 23,33 ± 5.77; 16,67 ± 11.55; 103,33 ± 5.77; dan 146,67 ± 5.77 menit. Kesimpulan: Infus bunga Widuri 5% b/v efektif sebagai antiparamphistomiasis ditinjau dari rerata waktu mortalitas yang berbeda bermakna (p<0,05) lebih rendah dibandingkan Albendazol 10% b/v.
PENGARUH PENYULUHAN ONLINE TERHADAP PERUBAHAN PENGETAHUAN DAN SIKAP SISWA SMK NEGERI 1 KOTA BIMA MENGENAI TINDAKAN ABORSI PADA TAHUN AJARAN 2020 Anisa; Syamsun, Arfi; Jumsa, Muhammad Rizkinov
Jurnal Kedokteran Vol 10 No 1 (2021): volume 10 nomor 1 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i1.455

Abstract

Background: Lack of knowledge about safe sexual intercourse can lead to pregnancy. Pregnancy has put adolescents in a situation that is awry, therefore abortion could happen. Abortion is the release of conception before the fetus can live outside the womb. Objective: To determine the effect of counseling on changes in knowledge and attitudes of students of SMK Negeri 1 Kota Bima regarding abortion in the 2020 academic year. Method: This was an analytical pre-experimental study with a pretest-post test group design. The research was held in SMK Negeri 1 Kota Bima. The research was conducted in September - October 2020 with a total sample of 36 students of grade XI majoring in Batik and Craft Textiles. Samples were taken by total sampling. Data analysed using Wilcoxon statistical test. Result: The knowledge before counseling was in the sufficient category, which were 22 people (61.1%) and after the counseling, it turned into a good category, which were 27 people (75.0%). The student’s attitude before counseling showed a positive attitude, where 33 people (91.7%) disagree with the abortion and after the counseling, changes to 100.0%. The results of the test for the knowledge and attitude after pretest-post test showed a significant value, which was 0,000, indicating that there was a significant change based on statistics for the knowledge. Meanwhile, the significant value for the attitude after pretest-post test showed a result of 0,083, indicating that there is no statistically significant change. Keywords: Counseling, Knowledge level, Attitude, Abortion
Korelasi Skor Mini Mental State Examination (MMSE) dan Montreal Cognitive Assessment Versi Indonesia (MoCA-Ina) Sebagai Instrumen Evaluasi Fungsi Kognitif pada Pasien Epilepsi di Kota Mataram Nurfadia, Muhammad Fabian; Harahap, Herpan Syafii; Rizki, Mohammad; Sahidu, Muhammad Ghalvan; Hunaifi, Ilsa
Jurnal Kedokteran Vol 10 No 1 (2021): volume 10 nomor 1 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i1.470

Abstract

Background: Epilepsy is the highest prevalence diseases in neurology. The decreased of cognitive function is one of the complications which is important. The purpose of this study is to determine the correlation between Mini Mental State Examination (MMSE) and Montreal Cognitive Assessment in Indonesian Version (MoCA-Ina) score on patient with epilepsy in Mataram. Method: This is an observational cross-sectional study with 56 subjects with epilepsy from West Nusa Tenggara 2 center hospital. Data that collected from the samples were MMSE and MoCA-Ina score. Beside of that patients’ characteristics data were also collected which is age, gender, education, seizure control, etiology of epilepsy, seizure type, antiepileptic drugs treatment, and smoking status from the subjects. Both instrument’s mean scores were analyzed for the correlation using Spearman correlation test. Result: This study showing that the subjects average age were 32.9 years old, female (55.4%), and low educated (62.5%). According to the clinical characteristics most subjects were not-depressed (67%), poor quality-controlled seizure (55.4%), idiopathic etiology (66.9%), generalized seizure (71.4%), and having monotherapy (85.7%). Most of the subjects were not a smoker (76.8%). In this study both the mean score of MMSE and MoCA-Ina were 25.3 and 21.3. MMSE and MoCA-Ina score mean have a strong correlation (r=0.766; p<0.001). Conclusion: MMSE and MoCA-Ina score mean on patients with epilepsy have a strong correlation. Therefore, both instruments could be used to evaluate cognitive function on patients with epilepsy

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