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Mutiara Medika: Jurnal Kedokteran dan Kesehatan
Published by Universitas Muhammadiyah Yogyakarta
ISSN : 14118033     EISSN : 26140101     DOI : 10.18196/mm
Core Subject : Health,
Health Professions Medicine & Pharmacology
Jurnal Mutiara Medika Fakultas Kedokteran dan Ilmu Kesehatan (MMJKK) Universitas Muhammadiyah Yogyakarta is a peer-reviewed and open access journal that focuses on promoting medical sciences generated from basic sciences, clinical, and community or public health research to integrate researches in all aspects of human health.
Arjuna Subject : -
Articles 934 Documents
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The Correlation between Lymphocyte Platelet Ratio and Gensini Score in Coronary Heart Disease Patients Muliana, Muliana; Rahmat, Basuki; Priyambodo, Seto
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 20, No 1: January 2020
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mm.200136

Abstract

The lymphocyte platelet ratio (LPR) is an inflammatory marker that can be used to identify the severity of coronary heart disease (CHD). This study aims to determine the correlation between the lymphocyte platelet ratio and Gensini scores in CHD patients. This research used correlative analytical research with a cross-sectional design. The sample was selected by consecutive sampling technique and obtained 51 respondents. The calculation of the LPR was carried out by dividing the number of platelets and lymphocytes in the volume unit of 103/mm3. Meanwhile, the Gensini score assessment was carried out by multiplying the percentage of blockages and location of blockages based on the result of coronary angiography. Based on the Gensini score, the sample in this study was classified as mild atherosclerosis with the Gensini score 25 points, and severe atherosclerosis with the Gensini score ≥25 points. The data were analyzed using the Pearson correlation test. The result showed that the average LPR value in samples with severe atherosclerosis was 124.6  and  115.3 in mild atherosclerosis. Based on the result of statistical analysis using the Pearson test, the p-value was 0.107. It can be concluded that there is no significant correlation between the lymphocyte platelet ratio and Gensini scores in CHD patients.
Social Demography Study of Gonorrhea and Syphilis at RSUD dr. Soedono Madiun Musy, Rahajeng; Widyasari, Vita; Rosmelia, Rosmelia
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 19, No 2: July 2019
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mm.190227

Abstract

An understanding of the socio-demographic characteristics is the first step to conduct preventive and promotive measures to reduce the number of sexually transmitted infections. This study described the socio-demographic cha-racteristics of gonorrhea and syphilis in dr. Soedono Hospital Madiun. A descripttive study with a quantitative approach used secondary data from outpatient medical records. This research was conducted in dr. Soedono Hospital Madiun, East Java. The samples used in this study were 61 patients who had been diagnosed with gonorrhea and syphilis in the period from July 2013 - June 2016. The data consisted of 50 (82%) medical records with the diagnosis of gonorrhea and 11 (18%) medical records with a diagnosis of syphilis. Characteristics of patients/respondents are the highest age group of 21-30 years, 22 female patients (36.1%), 55 male patients (90.2%), unmarried status 33 people (54.1%), work as private employees 37 people (60.7%), pay without insurance 48 people (78.7%), and live around Madiun 52 (86.0%). The socio-demographic factors were dominant in patients with gonorrhea and syphilis in dr. Soedono Hospital period of 2013-2016 was 21-30 years old, male, unmarried, living as private sector employees, pay without insurance, and Madiun origin.
The Influence of Hypertension and High-Density Lipoprotein on the Diabetic Nephropathy Patients Putri, Enda Silvia; Marniati, Marniati; Husna, Arafah; Maifizar, Afriani
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 20, No 1: January 2020
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mm.200139

Abstract

Diabetes complication of kidney failure begins with poor control of High-Density Lipoprotein (HDL) levels causing constriction of efferent arterioles affecting microalbuminuria, which triggers hypertension due to damage to blood vessels, with scarring in the filtration system of the central part of the kidneys. The Objective of the research was to analyze the influence of hypertension and HDL on the diabetic nephropathy patients. The study was an observational analytic study with a case-control design. The research sample consisted of 32 sample cases of patients with type II DM complications of kidney failure, and 32 control samples were DM type II patients without complications of kidney failure in dr. Pirngadi Hospital, Medan with accidental sampling technique. Data were generated by using questionnaires and medical records and analyzed by using the chi-square test, independent t-test, Mann-Whitney, and multivariate logistic regression to identify the effect of HDL and hypertension with DM type II complications of kidney failure. The Result of multivariate analysis showed hypertension OR; 17.845, and HDL OR; 7.049. The Conclusion showed that the most dominant factor that influenced the incidence of kidney failure complications in DM type II patients was hypertension at the Population Attributable Risk of 91%.
THE ADHERENCE TO FIXED-DOSE COMBINATION ANTIRETROVIRAL THERAPY AND VIRAL LOAD IN HIV PATIENTS Auliannissa, Salma; Bustamam, Nurfitri; Ningsih, Sri Rahayu
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 20 No 1: January 2020
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Antiretroviral fixed-dose combination (FDC ARV) has been used in HIV patient therapy. The therapy is recommended to be monitored using a viral load (VL), reflecting the amount of HIV in the blood. Since 2015, the VL testing has been carried out at Pengayoman Cipinang Hospital. However, the evaluation of adherence to the FDC antiretroviral therapy on VL has never been conducted. This study aims to determine the relationship between the adherence level to the FDC ARVs and VL at Pengayoman Cipinang Hospital in 2015-2018. The study used a cross-sectional design and a random sampling technique. The sample size was 70, and data generated from the medical record. Kruskal Wallis test showed no differences in the level of adherence in the group based on gender, education level, marital status, employment status, and the risk factor for HIV. However, there was a significant difference in the age group. Cross-tab data showed virological failure (VL> 400 copies/ml) was found in 1.8% of patients with good adherence, 75% of patients with moderate adherence, and 100% of patients with poor adherence. The Chi-square test showed a significant relationship between adherence to FDC ARV and VL (p=0.000). It can be concluded that there was a significant relationship between the level of adherence in taking ARV FDC and viral load.
CORTICOSTEROID-INDUCED CENTRAL SEROUS CHORIORETINOPATHY Nursalim, Ade John; Sumual, Vera
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 20 No 1: January 2020
Publisher : Universitas Muhammadiyah Yogyakarta

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Abstract

Central Serous Chorioretinopathy (CSC) is a condition where there is an accumulation of serous fluid in the retinal pigment epithelium layer. The abnormality in the retinal pigment layer of the eye causes vision loss and serous detachment. CSC has a variety of causes, one of which is corticosteroid therapy. This article aims to report a case of a 27-year-old male patient who was diagnosed with CSC. The risk factor indicating CSC, in this case, was long-term oral and the use of a nasal spray to treat patient?s allergic rhinitis. Patients have allergic rhinitis and sneezing. Thus, they are administered to consume tablets of 16 mg methylprednisolone three times a day. The patient has a history of using a nasal spray containing 0.05% mometasone furoate monohydrate for ten years in a row. The patient?s visual acuity is 6/6 on his right eye and 6/15 on his left eye. Posterior segment examination and optical coherence tomography (OCT) were considered effective in identifying the features of patients with CSC, and thus both were administered. It was further found that steroid therapy replacement and healthier lifestyle adjustments could sustain the symptoms and improve the patient?s well-being.
Structured Physical Activity did not Affect the Body Fat Percentage among Gymnastics Studio Members Widiastari, Erina Febriani; Taufik, Fatimah Eliana; Mukhtar, Diniwati
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 20, No 1: January 2020
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mm.200135

Abstract

The excess of body fat in the body can be associated with the risk of diabetes, cardiovascular disease, and other metabolic diseases. Activities which can reduce the body fat percentage is a structured physical activity. This study aims to identify the effect of the structured physical activity on the decrease in body fat percentage on members of the gymnastics studio. This study used one group of pretest-posttest design. The intervention was an aerobic exercise, conducted for a minimum duration of 150 minutes per week, and followed up for three months. The samples were selected by using purposive sampling andwere collected by measuring the respondent's weight with Bioelectrical Impedance Analysis at the beginning and the end of this study. The data were analyzed by using paired sample t-test. The result showed that the average of the body fat percentage on the pre-test was 33.156 %, and on the post-test was 32.920 %. Based on the data, there was a decrease in a body fat percentage on pre-test and post-test in 13 out of 25 respondents. The p-value was 0.357, and it can be concluded that the structured physical activity did not have a significant effect on the decreasein body fat percentage.
Pengaruh Konsentrasi Natrium Bikarbonat dalam Pasta Gigi Terhadap Streptococcus mutans Nisaa, Khairun; Widjijono, Widjijono
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 8, No 2 (s) (2008): Juli
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v8i2 (s).9408

Abstract

Antimicrobial substance into dentifrice is to destroy or inhibit the microorganisms that are associated with oral disease. One of the antimicrobial substances is a sodium bicarbonate. Sodium bicarbonate characterized as antimicrobial agent and buffering solution, the function of a buffer is to stand with change in pH after additional acid or base. This research is carried out to find out the effect of sodium bicarbonate concentration dentifrice to the growth of Streptococcus mutans. This research is an experimental laboratory. One millimeter suspension of Streptococcus mutans inoculated in MHA. After wards the agar was divided into 5 sectors and each was made a well and each well was loaded sodium bicarbonate dentifrice with 5 %, 10%, 15%, 20% concentration. The media was incubated for 48 hours in 37°C. Potential antimicrobial was measured by sliding caliper with 0. 01 mm in accuracy. This research uses twenty five samples. Data analysis was done One-way ANOVA to know the effect variance concentration, and LSDM5 to know mean difference between groups sodium bicarbonate. The result of this research showed that there were significant difference among the concentration sodium bicarbonate within dentifrice to the growth Streptococcus mutans @2 0.05). The result of LSD” 05 showed that there were significant differences between 0% concentration of sodium bicarbonate within dentifrice of 5%, 10%, 15%, and 20%. The conclusion of this research was that effect of sodium bicarbonate concentration within dentifrice to the growth of Streptococcus mutans.
Determination of Stunting Risk Factors Using Spatial Interpolation Geographically Weighted Regression Kriging in Malang Pramoedyo, Henny; Mudjiono, Mudjiono; Fernandes, Adji Achmad; Ardianti, Deby; Septiani, Kurniawati
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 20, No 2: July 2020
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mm.200250

Abstract

Stunting is the condition toddlers have Stunting is the condition toddlers have less length or height if compared to age. The high percentage of stunting is influenced by several factors, namely access to healthy latrines, quality drinking water, hand washing behavior with soap, coverage of posyandu access and coverage of breast milk 1-6 months, and there are indications that if an area has a high stunting percentage, then there is a possibility that the nearest area has the same condition. So, the statistic method for this research use the spatial interpolation Geographically Weighted Regression Kriging. Geographically Weighted Regression (GWR) is a weighted regression in which the weighting function is used to describe the closeness of relations between regions. The weight used is distance based weight dan weighting by area (contiguity). Ordinary kriging method calculated with semivariogram which is one function to describe and model the spatial autocorrelation between data of a variable and function as a measure of variance. The results showed that based on value GWR model with weight Fixed Gaussian Kernel better to use then the weighted GWR model Rook Contiguity. The Predicted of prevelensi stunting in the form of map based on interpolation GWR Kriging. Keywords: Stunting, GWR, and Kriging.
Pengaruh Pemberian Ekstrak Kayu Siwak (Salvadore persica) 50% Dengan Frekuensi Yang Berbeda Terhadap Ketahanan Email Gigi Rattus norvegicus Dewanti H, Gilang; Triawan, Andi
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 8, No 2 (s) (2008): Juli
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v8i2 (s).9402

Abstract

Miswak (Salvadora Persica) have antibacterial substances which can reduce the amount of bacteria in mouth so the tooth become healthy and prevent incidence of holey tooth. Intention of this research is to analyze usage of 5 0% miswak extract with different frequencies (1 x one day, 3 days once and once a week) to acid resistance of Rattus norvegicus tooth enamel.Research subject use I5 Rattus norvegicus at the age of 20 old days. The treatment is given 50% miswak extract topically on the incisivus tooth of Rattus norvegicus lower jaw with different frequencies. Each group (consist of 5 Rattus norvegicus) divided based on the frequencies that giving. The frequencies are I x one day, once every 3 day and once every a week. Treatment conducted during 30 day. After Rattus norvegicus in the age of 51 days, incisivus tooth of Rattus norvegicus taken away from lower jaw. After that phosphoric acid gel 37% applied above entire/all surface of tooth. We roentgen the tooth with digitally periapical Roentgen and calculated the damage on the enamel with score.Research result indicate that the given of 5 0% miswak extract with frequency I x one day, once every 3 days and once a week have significant difference (p=0,024) to acid resistance of Rattus norvegicus tooth enamel. Giving of 5 0% miswak extract with frequency I x is one day compared to with frequency once every 3 days also have difference which significant (p=0,042). While comparison between the giving of 50% miswak extract with frequency I x one day and once a week also have significant difference (p=0,020).Conclusions of research, the giving of miswak extract 5 0% with different frequency have different influence significantly to acid resistance of Rattus norvegicus tooth enamel. Miswak is a natural substance that can use for keep our mouth health. 
Perbandingan Pemberian Ekstrak Kayu Siwak (Salvadora persica) 50% Dan Larutan Sodium Fluorida 2% Terhadap Ketahanan Dentin Gigi Rattus norvegicus Ekanila, Maryanur; Triawan, Andi
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 7, No 2 (s) (2007): Juli
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v7i2 (s).9429

Abstract

Siwak memiliki banyak kegtmaan bagi kesehatan gigi dan mulut, diantaranya menghilangkan stain, memutihkan gigi, mengurangi plak dan gingivitis juga sebagai antitumor, efek bakteriosidal dan menstimulasi pertahanan gingiva, membantu kerusakan jaringan, serta menghambat pembentukan karang gigi. Sedangkan sodium fluorida terdapat khusus pada tulang dan khususnya di email dan dentin gigi dan digunakan untuk mencegah karies gigi, menghambat dekalsifikasi, menstimulasi remineralis asi serta menghambat pembentukan asam oleh kuman mulut.Penelitian ini bertujuan untuk menganalisis perbandingan antara penggunaan ekstrak kayu siwak 50% dan larutan sodium fluorida 2% terhadap ketahanan asam dentin gigi Rattus norvegicus. Penelitian dilakukan secara eksperimental laboratoris secara in vitro dan menggunakan 10 Rattus norvegicus. Perlakuan yang diberikan adalah pembeiian ekstrak kayu siwak secara topikal pada gigi rahang bawah 5 Rattus norvegicus dan pemberian larutan sodium fluorida secara topikal pada gigi rahang bawah 5 Rattus norvegicus. Pemberian ekstrak kayu siwak 5 0% dan larutan sodium fluoiida 2% dilakukan sejak Rattus norvegicus berumur 20 hari sampai Rattus norvegicus berumur 50 hari. Kemudian gigi Rattus norvegicus dietsa dengan gel asam fosfat 37% selama 60 detik lalu dirontgen digital periapikal dan di skor untuk mendapatkan data masing-masing vatiabel selanjutnya dilakukan uji statistik Mann- Whitney Test.Hasil uji statistik dengan Mann- Whitney Test didapat (p=0,221) karena (p 0,05) maka eksnak kayu siwak 50% mempunyai pengaruh yang tidak signifikan terhadap ketahanan dentin gigi Rattus norvegicus dibandingkan dengan larutan sodium fluorida 2%.Hasil penelitian menunjukkan bahwa ekstrak kayu siwak 50% dan larutan sodium Fluorida 2% memiliki pengaruh yang tidak berbeda secara signifikan terhadap ketahahan dentin gigi Rattus norvegicus.

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