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Majalah Obstetri dan Ginekologi
Published by Universitas Airlangga
ISSN : 08540381     EISSN : 25981013     DOI : 10.20473/mog.V27I32019.90-93
Core Subject : Health,
Health Professions Medicine & Pharmacology
Majalah Obstetri & Ginekologi (MOG) or the Journal of Obstetrics & Gynecology Science is a scientific journal published by the Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia, in collaboration with the Indonesian Obstetrics and Gynecology Association (POGI) of Surabaya branch.
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Articles 298 Documents
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Maternal and fetal characteristics associated with successful Vaginal Birth After Cesarean (VBAC) in Dr. Soetomo and Universitas Airlangga Hospitals, Surabaya, Indonesia Armawa, Syihab; Sulistyono, Agus; Akbar, Muhammad Ilham Aldika; Risa Etika
Majalah Obstetri & Ginekologi Vol. 33 No. 2 (2025): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V33I22025.105-112

Abstract

HIGHLIGHTS High VBAC success rate demonstrated with effective patient selection and intrapartum management. Cervical dilation >4 cm at admission identified as a critical predictor of VBAC success.   ABSTRACT Objective: This study aims to evaluate the maternal and fetal characteristics associated with successful vaginal birth after cesarean (VBAC) at Dr. Soetomo General Academic Hospital and Universitas Airlangga Hospital in Surabaya, Indonesia. Materials and Methods: A retrospective analytic study was conducted using a total sampling method to review medical records from January 2021 to December 2022. Inclusion criteria encompassed singleton pregnancies with a previous one-time low-segment cesarean section, vertex presentation, and no contraindications to vaginal delivery. A total of 46 eligible cases were analyzed following exclusion criteria. Results: Among the studied variables, cervical dilation at admission and the 5-minute Apgar score were significantly associated with successful VBAC (p < 0.05). All patients presenting with cervical dilation >4 cm delivered vaginally, indicating a strong predictive value. In contrast, those with dilation <4 cm had a markedly higher rate of cesarean delivery. A higher Apgar score also correlated positively with VBAC success, suggesting favorable neonatal outcomes in these cases. Maternal BMI did not show a statistically significant association with VBAC success (p > 0.05), likely influenced by the predominance of obesity in the cohort. Other factors, including maternal age, parity, birth interval, gestational age, and neonatal birth weight, were not significantly associated with the outcome. Conclusion: While most maternal and fetal variables did not significantly impact the likelihood of successful VBAC, cervical dilation on admission emerged as a critical clinical predictor. These findings emphasize the importance of intrapartum evaluation, particularly cervical assessment, in guiding delivery planning for women with prior cesarean sections.
The development of "TAMENG" flipchart for eradication of anemia in pregnancy in Sumber, Kabupaten Probolinggo, Indonesia Wardhana, Manggala Pasca; Sulistyono, Agus; Wahyuningtyas, Riska; Rahmatyah, Rizqy; Rosyada, Amrina; Rifdah, Salsabila Nabilah; Yusrika, Mirani Ulfa
Majalah Obstetri & Ginekologi Vol. 33 No. 2 (2025): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V33I22025.113-120

Abstract

HIGHLIGHTS The "TAMENG" flipchart significantly improved knowledge about anemia prevention among pregnant women. Nutritional status (mid-upper arm circumference) and history of anemia were strongly associated with anemia prevalence. Community-based, culturally relevant tools like the flipchart can effectively promote sustainable maternal health behaviors.   ABSTRACT Objective: This study aimed to evaluate the effectiveness of the "TAMENG" flipchart as an educational tool to improve knowledge about anemia prevention among pregnant women in Sumber, Kabupaten Probolinggo, Indonesia, and to explore associated risk factors for anemia, including nutritional status and supplementation practices. Materials and Methods: A community-based cross-sectional study was conducted in August 2024 as part of Universitas Airlangga’s Community Service Program. Pregnant women attending antenatal care in Sumber, Kabupaten Probolinggo were recruited based on ANC attendance and availability of hemoglobin test results. The "TAMENG" flipchart, designed with culturally relevant visuals and content on anemia prevention, was implemented during interactive education sessions. Demographic data, obstetric histories, and pre- and post-test knowledge assessments were collected. Statistical analysis was performed using chi-square tests to identify significant associations between variables. Results: Among 65 participants, 35.38% were anemic. Significant factors associated with anemia included nutritional status (60.9% of anemic women had mid-upper arm circumference <23.5 cm; p = 0.019) and history of anemia (30.4% vs. 9.5%; p = 0.032). Knowledge scores significantly improved post-intervention for 90.5% of non-anemic women and 100% of anemic women. Employment status and supplementation practices showed notable trends but were not statistically significant. Conclusion: The "TAMENG" flipchart effectively increased knowledge and awareness about anemia prevention. Tailored interventions addressing nutritional deficiencies, supplementation adherence, and family involvement can enhance maternal health outcomes in rural communities.
Efficacy and role of vitamin D (25-OH-D serum) in the treatment of endometriosis: A systematic review Diani, Yuli Ayu; Wiyasa, I Wayan Arsana
Majalah Obstetri & Ginekologi Vol. 33 No. 2 (2025): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V33I22025.132-140

Abstract

HIGHLIGHTS Endometriosis frequently causes pelvic damage and infertility, and vitamin D has been proposed as a therapeutic option owing to its involvement in immune regulation and reproductive health. Vitamin D may contribute to the modulation of inflammatory pathways and decrease the risk of hyperplasia and malignancy, with several studies indicating that it might also impact infertility related to endometriosis. ABSTRACT Objective: Vitamin D, an essential element in women’s reproductive health, has shown potential benefits in endometriosis management by improving plasma concentrations and modulating immune responses in chronic inflammatory conditions, including endometriosis. This study aimed to elucidate the pivotal role of vitamin D in alleviating chronic pain and infertility associated with endometriosis and to provide new insights into its therapeutic application in reproductive medicine. Materials and Methods: This systematic review examined literature retrieved from PubMed, ScienceDirect, ResearchGate, and Google Scholar, screening 1,156 records and including 20 studies for qualitative assessment. The review focused on the therapeutic contribution of vitamin D in endometriosis management. Eligible studies were those published in the last decade, in English, involving non-pregnant, healthy women, particularly patients with chronic pelvic pain or infertility. Accepted study designs comprised experimental, cohort, longitudinal, case reports, pilot, and observational studies. Excluded were non-English articles, animal or pregnant populations, reviews, inaccessible full texts, and studies lacking relevance to vitamin D or endometriosis. Results: Twenty selected studies were analyzed, encompassing 5,346 women and 60 girls aged 12–50 years, with or without endometriosis, from Iran, the USA, South Korea, Russia, Turkey, Brazil, Poland, Italy, Germany, and Japan. These studies indicated that multiple therapeutic approaches were attempted, suggesting that endometriosis may be partially ameliorated by vitamin D administration. Conclusion: This systematic review highlights that women with endometriosis presented with lower vitamin D levels; however, the evidence regarding supplementation efficacy remains uncertain. Further large-scale, rigorously designed trials are necessary to establish vitamin D’s therapeutic role in the management of endometriosis.
Global research trends in partograph: A bibliometric analysis Dhiya An, Alfun; Maulidya, Asri Nur; Ulfa, Maria
Majalah Obstetri & Ginekologi Vol. 33 No. 2 (2025): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V33I22025.152-163

Abstract

HIGHLIGHTS This study highlights growing global attention on the partograph as a part of labor monitoring. Partograph use remains inconsistent and affects clinical decision-making and management of labor. Future studies should focus on digital monitoring and policy effectiveness in intrapartum care as a part of enhancing maternal and neonatal outcomes.   ABSTRACT Objective: The present study aimed to clarify the emerging patterns in partograph utilization, its development, and its impact on clinical practice. Materials and Methods: A bibliometric analysis was conducted using Scopus as the primary database. Articles were retrieved using the keywords “Partograph” or “Partogram” and analyzed using two strategies: performance analysis (Scopus “analyze” function) and network analysis (VOSviewer and NVivo). Results: Five hundred and thirteen articles published between 1965 and 2025 were analyzed. Performance analysis revealed that the most cited studies focused on labor management, labor progression, and maternal and neonatal health outcomes. The leading publishing countries included Ethiopia, the United States, the United Kingdom, India, and South Africa. Network analysis identified strong connections between partograph research and healthcare quality, personnel delivery, and facilities. Research trends evolved from early studies on spontaneous delivery, dystocia, and maternal mortality to more recent investigations into partograph utilization as a healthcare service quality improvement tool. Pearson correlation analysis showed strong associations between partograph use and birth outcomes (0.81), mortality (0.78), and healthcare workers’ perspectives (0.76). Conclusion: Research on partograph utilization continues to expand, focusing on labor monitoring and its impact on maternal and neonatal outcomes. Recently, studies have shifted toward labor-management quality, healthcare service improvement, and patient safety. However, certain areas remain underexplored, presenting opportunities for further research.
Front Matter Vol. 33 No. 2 August 2025 Majalah Obstetri & Ginekologi
Majalah Obstetri & Ginekologi Vol. 33 No. 2 (2025): August
Publisher : Universitas Airlangga

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Abstract

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Back Matter Vol. 33 No. 2 August 2025 Majalah Obstetri & Ginekologi
Majalah Obstetri & Ginekologi Vol. 33 No. 2 (2025): August
Publisher : Universitas Airlangga

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Abstract

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Molecular mechanisms and biomarkers of autophagy in early onset preeclampsia: Key genes, pathways, and potential diagnostic/therapeutic targets Kusuma, Anak Agung Ngurah Jaya
Majalah Obstetri & Ginekologi Vol. 33 No. 3 (2025): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V33I32025.262-270

Abstract

HIGHLIGHTS Dysregulated autophagy in trophoblasts contributes to abnormal placentation and impaired spiral artery remodeling in early-onset preeclampsia. Oxidative stress and excessive mitochondrial ROS disrupt the autophagic balance, leading to cellular dysfunction and placental ischemia. Key autophagy-related genes (e.g., BECN1, LC3, ATG5, mTOR, TFEB) may serve as diagnostic or therapeutic targets in early-onset PE. Understanding the autophagy–oxidative stress interaction could inform biomarker development and novel interventions.   ABSTRACT The pathogenesis of preeclampsia (PE) remains incompletely understood, with multiple mechanisms proposed. Among these, dysregulation of autophagy has emerged as a critical factor. Autophagy is essential for implantation, placental development, and pregnancy maintenance. Extravillous trophoblasts (EVTs) invade the decidua and proximal myometrium under hypoxic conditions, and autophagy supports this invasive process. In PE, impaired placentation has been associated with abnormal autophagic activity in trophoblastic cells. Furthermore, oxidative stress and excessive mitochondrial reactive oxygen species (ROS) production contribute to the pathophysiology of PE, potentially driving both insufficient and maladaptive upregulation of autophagy depending on the cellular microenvironment. Thus, PE is characterized not by a uniform increase or inhibition, but rather by disrupted autophagic balance. This review aims to clarify the role of autophagy dysregulation in the pathogenesis of PE.
Vesicovaginal fistula with surgical interventions at Dr. Ramelan Naval Hospital, Surabaya, Indonesia Ayudelvi, Sahika Nisandi; Najmi, Risa; Amala, Ritma Visi; Ramadina, Rizka Indah; Konitatunisa, Salma Inas; Herdiyantini, Mita; Ardiana, Dian
Majalah Obstetri & Ginekologi Vol. 33 No. 3 (2025): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V33I32025.249-261

Abstract

HIGHLIGHTS Vesicovaginal fistula (VVF) cases in this study were primarily caused by hysterectomy, post-caesarean section surgery, and radiation therapy for cervical cancer. Symptoms experienced by patients included urine leakage from the vagina, foul odor, and pain during urination. The success rate of fistula repair using cystography and fistula repair procedures was very high. The patients were able to urinate normally without pain or vaginal leakage.   ABSTRACT Objective: Evaluating the risk factors and outcomes of surgical interventions in patients with vesicovaginal fistula at Dr. Ramelan Naval Hospital Surabaya, Indonesia, from January 2019 to December 2023. Case Series: There were 6 cases of vesicovaginal fistula that underwent surgical interventions at Dr. Ramelan Naval Hospital, Surabaya, from 2019 to 2023 that met the inclusion criteria. The majority of vesicovaginal fistula cases occurred as a result of hysterectomy, accounting for 4 cases (67%), followed by caesarean section surgery (16%) and radiation therapy for cervical cancer (17%). Symptoms experienced by the patients included urine leakage from the vagina, foul odor, and pain during urination. The vesicovaginal fistulas that underwent surgical interventions were typically 0.5 to 3 cm in size. Most of the cases involved simple-type fistulas. A total of 5 cases (83%) were successfully repaired. These patients were able to urinate normally, without pain or vaginal leakage. However, 1 case (17%) experienced recurrent fistula with an increase in the number of fistulas and continued to experience pain during urination and leakage from the vagina, particularly during strenuous activities. Conclusion: The vesicovaginal fistula cases at Dr. Ramelan Naval Hospital Surabaya, Indonesia, from 2019 to 2023 showed a high therapeutic success rate. Among 6 patients that we studied, the majority of cases were caused by hysterectomy, characterized as simple-type fistulas, with 83% of the cases were successfully repaired.
Blood Pressure Variability as a predictor of maternal and neonatal outcomes in preeclampsia Mulyana, Ryan Saktika; Pemayun, Tjokorda Gede Astawa; Narayani, Ida Ayu; Adikarya, I Putu Gede Danika; Pradnyaandara, I Gusti Bagus Mulia Agung; Paramyta, I Gusti Ayu Cintya
Majalah Obstetri & Ginekologi Vol. 33 No. 3 (2025): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V33I32025.180-187

Abstract

HIGHLIGHTS Increased blood pressure variability (BPV) in preeclampsia is associated with a higher risk of maternal complications, such as prolonged hospitalization and eclampsia, as well as neonatal complications, including low birth weight and the need for NICU admission. Incorporating BPV monitoring into routine prenatal care may improve early detection of high-risk cases, allowing for timely interventions to reduce adverse maternal and neonatal outcomes.   ABSTRACT Objective: Preeclampsia remains a major cause of maternal and perinatal morbidity and mortality worldwide. This study aimed to evaluate the impact of blood pressure variability (BPV) on maternal and neonatal outcomes in preeclamptic patients, emphasizing its potential role in clinical management. Materials and Methods: A retrospective cohort study was conducted on 40 preeclamptic patients treated at Prof. Dr. I.G.N.G Ngoerah Hospital, Denpasar, Bali, between January 2020 and December 2022. BPV was determined from serial systolic and diastolic blood pressure measurements during antenatal care. Maternal outcomes included length of hospitalization, preterm birth, premature rupture of membranes, eclampsia, postpartum hemorrhage, ICU admission, and composite adverse events. Neonatal outcomes included birth weight, Apgar scores, NICU admission, stillbirth, congenital anomalies, and neonatal death. Statistical analyses were performed using bivariate and multivariate logistic regression methods, with variables of p < 0.25 included in final models. Results: High BPV was significantly associated with increased maternal adverse events (adjusted OR 13.66; 95% CI 2.26–82.43; p = 0.004) and neonatal adverse outcomes (p = 0.011). Specifically, it correlated with low birth weight (p < 0.001), shorter birth length (p = 0.003), preterm birth (p = 0.003), and higher NICU admission rates (p = 0.005). No significant association was observed with fetal distress, intrauterine growth restriction, or neonatal death. The study achieved a statistical power of 86.7%. Conclusion: Increased BPV in preeclampsia is strongly linked to adverse maternal and neonatal outcomes. Routine BPV monitoring may serve as an important tool for early risk identification and improved obstetric management.
Comparative analysis of stromal inflammatory cell infiltration and HPV infection status in cervical dysplasia and squamous cell carcinoma using the Klintrup-Mäkinen Scoring method Fahendra, Nicholas Adrian; Edbert, Daniel; Ardianto, Christian; Lilis, Lilis
Majalah Obstetri & Ginekologi Vol. 33 No. 3 (2025): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V33I32025.188-194

Abstract

HIGHLIGHTS KM score is a reliable method to help determine the diagnosis of cervical dysplasia and squamous cell carcinoma. KM score cannot be used to differentiate infection status in cervical dysplasia and squamous cell carcinoma.   ABSTRACT Objective: Cervical cancer is the second most common malignancy in women, with 604,127 new cases reported globally in 2020. Persistent high-risk human papillomavirus (HPV) infection is the primary cause. This study aimed to evaluate the relationship between stromal inflammatory cell infiltration using the Klintrup-Mäkinen (KM) score and HPV infection status in cervical dysplasia and squamous cell carcinoma (SCC). Materials and Methods: A cross-sectional study was conducted using secondary data from formalin-fixed paraffin-embedded (FFPE) cervical tissue samples diagnosed as dysplasia or SCC at Atma Jaya Catholic University of Indonesia from 2014 to 2022. HPV status was determined using PCR-based assays, while stromal inflammatory cell infiltration was assessed microscopically at 100× magnification and graded according to the KM scoring system by two blinded observers. Statistical analyses, including Chi-square and Spearman’s correlation tests, were performed using STATA/IC 15, with p < 0.05 considered significant. Results: A total of 38 samples were analyzed, comprising 20 (52.63%) cases of dysplasia and 18 (47.37%) cases of SCC. HPV positivity was identified in 70% of dysplasia and 94.44% of SCC cases. KM scores of 2/3, indicating moderate to severe inflammatory infiltration, were significantly more frequent in SCC (77.78%) compared to dysplasia (20%), showing a strong association with pathological diagnosis (p = 0.0019). However, no significant correlation was observed between KM score and HPV status in either lesion type. Conclusion: The KM scoring method provides a reliable and cost-effective approach for assessing stromal inflammatory cell infiltration in cervical lesions, aiding histopathological diagnosis, although it does not predict HPV infection status.

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