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Majalah Obstetri dan Ginekologi
Published by Universitas Airlangga
ISSN : 08540381     EISSN : 25981013     DOI : 10.20473/mog.V27I32019.90-93
Core Subject : Health,
Health Professions Medicine & Pharmacology
Majalah Obstetri & Ginekologi (MOG) or the Journal of Obstetrics & Gynecology Science is a scientific journal published by the Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia, in collaboration with the Indonesian Obstetrics and Gynecology Association (POGI) of Surabaya branch.
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Articles 298 Documents
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Placenta Accreta Spectrum in delivered women is associated with history of curettage: A case-control study at Dr. Moewardi General Hospital, Surakarta, Indonesia Prabowo, Helena Adelia; Anggraini, Nutria Widya Purna; Anggraeni, Asih; Setyawan, Sigit
Majalah Obstetri & Ginekologi Vol. 33 No. 1 (2025): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V33I12025.37-43

Abstract

HIGHLIGHTS Placenta Accreta Spectrum cases rise in proportion to the high frequency of uterine wall damage. A significant association was found between curettage history and Placenta Accreta Spectrum.   ABSTRACT Objective: Placenta Accreta Spectrum (PAS) involves abnormal placental adherence to the myometrium, causing severe obstetric hemorrhage and increased maternal morbidity and mortality (3,000–5,000 mL blood loss). Its global incidence has risen from 0.12% to 0.31%, linked to uterine trauma from cesarean sections or curettage. This study evaluates the association between curettage history and PAS. Materials and Methods: This study employed an analytical observational design with a case-control approach. Purposive sampling was utilized, resulting in the inclusion of 134 participants who met the predefined criteria. The study population consisted of women who delivered and were referred to Dr. Moewardi General Hospital, Surakarta, Indonesia, between May 2022 and May 2024. Data were analyzed using IBM SPSS version 25. The Chi-square test was applied to assess the association between variables at a significance level of p < 0.05, while logistic regression analysis was conducted to identify the most influential variables. Results: The study cohort comprised 67 patients diagnosed with PAS and 67 without PAS. A statistically significant association was observed between a history of curettage and PAS, as determined by the Chi-square test, with a p-value of 0.000. Logistic regression analysis further confirmed this association, yielding a p-value of 0.001 and an odds ratio (OR) of 5.769 (95% CI: 2.090–15.928) for a history of curettage. Conclusion: A history of curettage is significantly associated with the development of PAS. Patients with a prior curettage procedure are 5.769 times more likely to develop PAS compared to those without such a history.
Breaking the cycle of infertility with clomiphene citrate and letrozole for successful ovulation induction for obese women with PCOS Permadi, IGN Wiranta; Prasetyaji, IMN Wiranta
Majalah Obstetri & Ginekologi Vol. 33 No. 1 (2025): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V33I12025.44-52

Abstract

HIGHLIGHTS Polycystic ovarian syndrome (PCOS) is a hyperandrogenous state with oligo-anovulation. Letrozole is more efficient than CC in promoting ovulation and facilitating pregnancy in women with PCOS who are overweight or obese.   ABSTRACT Objective: Indonesia has a higher prevalence of PCOS, a common endocrine disorder that affects 4% to 8% of women who are of reproductive age. Obesity, insulin resistance, and anovulatory infertility are all linked to PCOS. The ability of letrozole and clomiphene citrate (CC) to induce ovulation in overweight or obese PCOS patients was examined in this meta-analysis. Materials and Methods: PRISMA criteria were followed when conducting a systematic literature search utilizing PubMed, Google Scholar, Cochrane Library, and ScienceDirect. Keywords included PCOS, obesity, clomiphene, and letrozole. Studies published between 2000 and 2024 in English, with full-text accessibility, were included. The search yielded 260 studies, of which nine were selected for quantitative synthesis. Results: Letrozole showed a 12% increase in ovulation and a 33% increase in pregnancy rates compared to clomiphene citrate (CC). There was no discernible difference in the two groups' endometrial thickness. This meta-analysis finds that letrozole is more successful than CC in triggering ovulation and achieving conception in overweight or obese PCOS patients. Conclusion: In women with PCOS who are overweight or obese, letrozole works better than clomiphene citrate (CC) to induce ovulation. Because it is accessible and reasonably priced, CC is still the first-line treatment, even if its efficacy is lesser. As a second-line therapy, letrozole is advised for women who are resistant to or do not react to CC.
Front Matter Vol. 33 No. 1 April 2025 Majalah Obstetri & Ginekologi
Majalah Obstetri & Ginekologi Vol. 33 No. 1 (2025): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V33I12025.%p

Abstract

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Back Matter Vol. 33 No. 1 April 2025 Majalah Obstetri & Ginekologi
Majalah Obstetri & Ginekologi Vol. 33 No. 1 (2025): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V33I12025.%p

Abstract

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Cervical cancer screening before hysterectomy in pelvic organ prolapse patients: Is it essential? A case series Aryasatiani, Ekarini; Surya, Raymond; Harjanti, Dyonesia Ary; Ilona, Florinda; Kartika, Chandra Dewi; Cantika, Catalya Christina; Tenka, Lisda
Majalah Obstetri & Ginekologi Vol. 33 No. 2 (2025): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V33I22025.173-179

Abstract

HIGHLIGHTS More advanced cervical precancerous histopathological findings compared with cervical cytology are observed in POP patients undergoing vaginal hysterectomy. Routine use of preoperative biopsy or ultrasound in POP patients undergoing vaginal hysterectomy cannot be recommended.   ABSTRACT Objective: Pelvic organ prolapse (POP) results from weakening of the pelvic floor musculature. The reported prevalence of unexpected premalignant and malignant pathologies following hysterectomy ranges from 0.2 to 0.8%. This study aims to present a case series of patients with POP who underwent vaginal hysterectomy (VH) after preoperative evaluation for abnormal cervical cytology, which subsequently demonstrated more advanced histopathological findings. Case Series: Case 1: A 55-year-old woman, P3A0, was diagnosed with third-degree uterine prolapse and cystocele. Pap smear revealed atypical glandular cells of undetermined significance (AGUS). Histopathological examination after VH demonstrated vaginitis and metaplastic chronic cervicitis with atypia progressing to mild dysplasia of endocervical epithelial cells/low-grade squamous intraepithelial lesion (LSIL). Case 2: A 62-year-old woman, P5A0, was diagnosed with third-degree uterine prolapse. Pap smear revealed atypical squamous cells of undetermined significance (ASCH). Histopathological evaluation after VH demonstrated high-grade squamous intraepithelial lesion (HSIL) up to carcinoma in situ with microinvasive glandular involvement and focal extension. Conclusion: Given that cervical cancer remains the second leading cause of mortality among women in Indonesia, preoperative screening for precancerous gynecological lesions and malignancy is strongly recommended.
Long COVID in vaccinated women with Polycystic Ovary Syndrome: A retrospective cohort pilot study Muharam, R; Bagastoro, Aswan; Faradina, Anindita Abigail; Yo, Edward Christopher; Irzanti, Alisha Nurdya; Sumapraja, Kanadi; Harzif, Achmad Kemal; Pratama, Gita; Maidarti, Mila; Silvana, Vita; Wiweko, Budi; Hestiantoro, Andon
Majalah Obstetri & Ginekologi Vol. 33 No. 2 (2025): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V33I22025.89-96

Abstract

HIGHLIGHTS Among women with PCOS, many still reported persistent long COVID symptoms such as hair loss and fatigue. COVID-19 vaccination does not exacerbate symptoms of PCOS, which further emphasizes the importance of completing COVID-19 doses for women with PCOS to avoid long COVID sequelae.   ABSTRACT Objective: Long COVID, or the persistence of symptoms after acute COVID-19 illness, can affect individuals with pre-existing health conditions such as polycystic ovary syndrome (PCOS). Long COVID and PCOS may share overlapping pathogenesis which potentially exacerbate one another. The aim of this study was to evaluate the symptoms of long COVID in women with PCOS who have been vaccinated and investigate whether COVID-19 vaccination or infection worsened PCOS symptoms. Materials and Methods: We carried out a retrospective cohort study on 44 women with PCOS who have been vaccinated and previously diagnosed with COVID-19. Questionnaires were distributed to find out the effect of COVID infection and vaccines in these women, as well as the symptoms of long COVID-19. Results: Of all participants, 28 women (70%) continued to report persistent long COVID symptoms, with the highest number of complaints being fatigue and hair loss. The results, using Mann-Whitney test, showed that there was no difference in PCOS symptoms before and after COVID-19 vaccination (p = 0.520) or after COVID-19 infections (p = 0.241). Although this study revealed a substantial prevalence of long COVID symptoms among women with PCOS, an encouraging finding emerged: neither the administration of COVID-19 vaccination nor prior infection with COVID-19 had a significant impact on PCOS-associated symptoms. Conclusion: This study further underscores the importance of vaccination for all individuals, including women with a history of PCOS. Furthermore, the purpose of COVID-19 vaccination is to mitigate symptom severity, thus potentially diminishing the occurrence of long-term COVID-19 symptoms in future cases.
Cranberry extract for urinary tract infection treatment in pregnancy: A systematic review Hakim, Rahmawati Abdul; Putri, Dhian Eka; Rahajeng
Majalah Obstetri & Ginekologi Vol. 33 No. 2 (2025): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V33I22025.121-131

Abstract

HIGHLIGHTS Cranberry represents a promising and effective alternative for both the treatment and prevention of urinary tract infections during pregnancy. Cranberry acts by inhibiting bacterial adhesion to the urinary tract epithelium and exerting direct antibacterial activity.   ABSTRACT Objective: Urinary tract infections (UTIs) represent the second most common infectious disease worldwide, affecting nearly 150 million people annually. Owing to anatomical and physiological alterations, UTIs are especially frequent during pregnancy, manifesting with symptoms including dysuria, cloudy urine, increased urinary frequency, and occasionally hematuria. Recurrent UTIs are defined as two or more episodes within six months or three episodes within a year. Cranberries are widely recognized for their potential in preventing UTIs during pregnancy. Their protective action involves blocking the adhesion of uropathogenic bacteria to the urinary tract epithelium, a process mediated by phenolic compounds and A-type proanthocyanidins (PACs). Materials and Methods: In this systematic review, the authors searched PubMed, ScienceDirect, ResearchGate, and Google Scholar for eligible articles published from 2013 to 2024. The search strategy employed Medical Subject Headings (MeSH) and keywords pertaining to Cranberry Extract/Juice and UTI Assessment Methods in Pregnancy. Search expressions were adapted to the specific requirements of each database to optimize retrieval precision. All identified studies were assessed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Results: Of the 30 studies included, a daily administration of 500 mg cranberry extract over six months exhibited notable effectiveness as an alternative therapeutic approach for UTIs in pregnancy. Conclusion: Cranberry (Vaccinium macrocarpon) extract prevents UTIs by impeding bacterial adherence and exerting antibacterial properties. This review supports cranberry as a promising and safe alternative for UTI prevention and management in pregnancy, appropriate for routine daily use.
Maternal, socioeconomic and healthcare factors associated with postpartum maternal mortality in Papua Province, Indonesia, based on secondary data analysis of IDHS 2020 Safitri, Dian Laily; Handayani, Samsriyaningsih; Prasetyo, Budi; Jayanti, Ratna Dwi
Majalah Obstetri & Ginekologi Vol. 33 No. 2 (2025): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V33I22025.97-104

Abstract

HIGHLIGHTS Postpartum maternal mortality demonstrates associations with determinants including parity, place of residence, proficiency in the Indonesian language, socioeconomic status or wealth index, type of delivery attendant, and place of childbirth. Proficiency in the Indonesian language constitutes the most dominant factor, plausibly indicating inequalities in healthcare access, levels of health literacy, and conditions of geographic or social marginalization.   ABSTRACT Objective: This study utilized data from the Indonesia Demographic Health Survey (IDHS) 2020 to examine the relationship between postpartum maternal mortality and several determinants, including maternal, socioeconomic, and healthcare-related factors in Papua Province. Materials and Methods: A cross-sectional design with a quantitative analytical framework was applied, drawing on secondary data from IDHS 2020. The sample comprised 14,802 women aged 15–49 years. Data were analyzed through a simple logistic regression test for bivariate analysis with a 95% confidence level (a = 0.05). Subsequently, multivariate multiple logistic regression analysis was conducted on variables with a p-value of less than 0.25. Results: Findings demonstrated that all variables (parity p<0.001 AOR=0.533 95% CI 0.375–0.758; place of residence p=0.001 AOR=2.526 95% CI 1.438–4.436; proficiency in Indonesian language p<0.001 AOR=0.039 95% CI 0.031–0.050; delivery attendant and place of birth p<0.001 AOR=0.118 95% CI 0.142–0.249, whereas wealth index status p=0.972 AOR=1.010 95% CI 0.565–1.806) showed a significant negative association with postpartum maternal mortality (p<0.05), except for the wealth index. The strongest association, with an odds ratio (OR) of 0.039, was identified in Indonesian language proficiency, indicating a 25.64-fold increase. Conclusion: The findings provide a crucial evidence base for the development of policies and interventions aimed at lowering postpartum maternal mortality in Papua Province. Proficiency in the Indonesian language emerged as the most influential factor, underscoring the potential for targeted interventions and improved healthcare outcomes.
Differences in factors associated with postpartum hemorrhage in developed and developing countries: A systematic review Handayani, Sri Astuti; Kartini, Farida
Majalah Obstetri & Ginekologi Vol. 33 No. 2 (2025): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V33I22025.141-151

Abstract

HIGHLIGHTS Analysis of maternal and fetal risk factors associated with postpartum hemorrhage, comparing data from both developed and developing countries. There are differences in the risk factors for postpartum hemorrhage between developed and developing countries.   ABSTRACT Objective: This study aimed to assess maternal and fetal risk factors for post-partum hemorrhage in both developed and developing countries. Materials and Methods: A systematic review methodology was employed, incorporating a descriptive design. The study followed Joanna Briggs Institute (JBI) techniques, the PCC framework, and the PRISMA-ScR checklist. Article searches were conducted across four databases: Research Rabbit, Science Direct, Wiley, and PubMed. Articles published in English between 2019 and 2024 that met the inclusion criteria were selected. The search terms included combinations of “Postpartum women” OR “Puerperium” AND “Risk factors” OR "Risky conditions” AND “Postpartum hemorrhag*” “Postpartum bleeding” and “Developed countr*” AND “Developing countr*”. Results: Out of 906 articles, 20 met the inclusion criteria, representing both developed and developing countries. The findings were categorized into two themes: risk factors in developed versus developing countries. In developed countries, PPH risk factors are often linked to medical interventions and prolonged labor management, while in developing countries, the focus shifts to conditions like anemia, uterine overdistension, and trauma from delivery practices. Sociocultural disparities further exacerbate risks in both settings. Conclusion: The study reveals significant differences in PPH risk factors between developed and developing countries. By reviewing existing research, it identifies factors that can influence PPH occurrence. The findings emphasize the need for developing policies to screen pregnant, maternity, and postpartum women to mitigate PPH risk.
Pregnancy: A window of opportunity for refining and mitigating the fetal origins of adult health and disease, and maternal cardiovascular futures Joewono, Hermanto T
Majalah Obstetri & Ginekologi Vol. 33 No. 2 (2025): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V33I22025.164-172

Abstract

HIGHLIGHTS Maternal nutrition, mental health, and environmental factors during pregnancy significantly influence the long-term physical and mental health of offspring, supporting the concept of Fetal Origins of Adult Disease (FOAD) and Developmental Origins of Health and Disease (DOHaD). Adverse pregnancy outcomes like preeclampsia and gestational diabetes increase the mother's future risk of cardiovascular disease, highlighting the need for broader maternal health strategies beyond childbirth.   ABSTRACT This review explores the profound impact of pregnancy on fetal development and long-term maternal cardiovascular health, emphasizing how early-life conditions shape lifelong health. The concept of Fetal Origins of Adult Disease (FOAD) or Developmental Origins of Health and Disease (DOHaD) is discussed, highlighting how maternal nutrition and environmental factors during pregnancy predispose offspring to chronic diseases later in life. Maternal mental health is also explored, with depression and anxiety during pregnancy linked to lasting effects on offspring, including increased risks of mental health disorders and chronic conditions in adulthood. The study "Like Mother, Like Daughter" is examined to illustrate intergenerational risks such as preeclampsia and intrauterine growth restriction (IUGR), emphasizing the role of maternal health. Additionally, the long-term cardiovascular consequences of adverse pregnancy outcomes—such as preeclampsia, gestational diabetes, and preterm birth—are discussed, noting that they elevate the mother's risk of cardiovascular disease (CVD) in later life. The rising prevalence of obesity during pregnancy further exacerbates these risks. The paper calls for a shift in obstetrics from a narrow focus on pregnancy management to a broader approach that addresses both maternal and fetal health for long-term benefits. By recognizing pregnancy as a critical window to influence future health, comprehensive strategies could help mitigate chronic diseases in both mothers and children

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