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Majalah Obstetri dan Ginekologi

MOG
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Published by Universitas Airlangga

ISSN : 08540381 EISSN : 25981013 DOI : 10.20473/mog.V27I32019.90-93

Core Subject : Health,

Health Professions Medicine & Pharmacology

Majalah Obstetri & Ginekologi (MOG) or the Journal of Obstetrics & Gynecology Science is a scientific journal published by the Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia, in collaboration with the Indonesian Obstetrics and Gynecology Association (POGI) of Surabaya branch.

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Articles 298 Documents

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Role of aspirin dose in reducing uterine artery resistance in 16-24 weeks pregnant women with abnormal uterine artery resistance Muhammad Arief Adibrata; Agus Sulistyono; Ernawati Ernawati
Majalah Obstetri dan Ginekologi Vol. 26 No. 3 (2018): December
Publisher : Universitas Airlangga

Objectives: To compare the decrease of resistance index (RI) from uterine artery in pregnant woman receiving low dose aspirin therapy between 80 mg/day and 125 mg/day who had abnormal doppler velocimetry (DV) ultrasound examination at 16-24 weeks.Materials and Methods: An experimental study using double blind randomized clinical trial design. Subjects were from Mulyorejo and Kalijudan public health service in Surabaya, that included pregnant women with 16-24 weeks of pregnancy with abnormal uterine artery velocimetry ultrasound. The results of ultrasound Doppler examination were divided into four levels; normal (RI<0.58; (-) diastolic notching), level I (RI> 0.58; (-) diastolic notching), level II (RI<0.58; (+) disatolic notching) and level III (RI> 0.58; (+) diastolic notching). Uterine doppler ultrasound examination was performed at Fetomaternal Division, Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo Hospital, Surabaya, Indonesia, by fetomaternal consultants before and after the admin-istration of low-dose aspirin of 125 mg/day and 80 mg/day for four weeks.Results: Ninety subjects were obtained and randomized into 2 groups, with 45 subject in each group. Before treatment, in 125 mg/day group those with level I were 34 subjects and level III 11 subjects. In 80 mg/day group, level I 41 subjects, level II 2 subjects and level III 2 subjects. After 4 weeks of treatment, a second DV USG was performed in Aspirin 125 mg/day group. Normal were 40 subjects, level I 4 subjects, and level III 1 subject. In aspirin group 80 mg/day, normal 22 subjects, level I 19 subjects and level III 4 subjects. The analysis was performed with Wilcoxon test before and after treatment in both aspirin treatment group 125 mg/day and 80 mg/day with p value respectively, p=0.001 and p=0.005.Conclusion: Compared with aspirin of 80 mg/day, aspirin of 125 mg/day is more superior to decrease uterine arterial resistance in pregnant women with ultrasound uterine arterial doppler velocimetry at 16-24 weeks gestational age.

Resurgence of placenta accreta in Indonesia Rozi Aditya Aryananda
Majalah Obstetri dan Ginekologi Vol. 26 No. 3 (2018): December
Publisher : Universitas Airlangga

Placenta accreta is a common term used for defining a clinical condition which part or all of the placenta attaches to the myometrium that difficult to remove. Placenta accreta is a placental disorder which has been around for a long time and became a resurgence in Indonesia since 2016 with its incidence reached 2% and is still increasing until now. Placenta accreta is one of the most terrifying conditions faced by gynecologists and resulted in the increase of mortality and morbidity of pregnant women in Indonesia. In the United States, the incidence increased from less than 1 per 2000 pregnancies in 1980 to around 1 per 500 pregnancies until recently. The increased cases of placenta accreta is always directly proportional to the cesarean delivery rates.

Effect of bone marrow mesenchymal stem cells transplantation on BMP-15 expression and Graafian follicle count in mice model of endometriosis Ratriana Via Parasti; Widjiati Widjiati; Sri Ratna Dwiningsih
Majalah Obstetri dan Ginekologi Vol. 26 No. 3 (2018): December
Publisher : Universitas Airlangga

Objectives: To determine the effect of bone marrow mesenchy-mal stem cells (BMSCs) on BMP-15 expression and Graafian follicle count in endometriosis mice.Material and Methods: This study was a laboratory randomized clinical trial on Mus musculus. The object of the study was 42 mice which were divided into 3 groups, the control, endome-triosis, and endometriosis + BMSCs groups. Comparison of BMP-15 expression and Graafian follicle count between groups was evaluated.Results: Immunohistochemical analysis showed that BMP-15 expression in control, endometriosis, and endometriosis + BMSCs groups had p=0.551, p=0.446 and p=0.917 with ANOVA test p=0.273, indicating no statistically significant differences between groups . Graafian follicular count in the three groups had p=0.31, p=0.001, and p=0.006, with the Kruskal-Wallis test p=0.001. Graafian follicles in the endometriosis + BMSCs group were higher than those in control and endometriosis groups.Conclusion:In the endometriosis mouse model with bone mar-row stem cell transplantation the BMP-15 expression in each group did not show a difference, but a significant difference was found in the number of Graafian follicles.

Fifty percent of food restriction during gestation reduced the dendritic density of cerebrum and cerebellum of Rattus norvegicus newborn Anwar Fauzi; Widjiati Widjiati; Hermanto T Joewono
Majalah Obstetri dan Ginekologi Vol. 26 No. 3 (2018): December
Publisher : Universitas Airlangga

Objectives: To analyze the influence of 50 percent food restriction during pregnancy to the dendritic density of cerebellum and cerebellum of newborn Rattus norvegicus.Materials and Methods: Laboratory experimental study with single blind randomized post-test only control group design using animal model; pregnant Rattus norvegicus as treatment models. Subjects were divided into two groups: control group and treatment group which was exposed to 50% food restriction (FR 50%). At day 21, both group sacrificed and the cerebrum and cerebelum of the offsprings were prepared and stained with silver impregnation. We used parametric independent t-test in analyzing dendritic density.Results: In the cerebrum there was a significant difference in dendritic density between control (4.98+2.17) and treatment (2.69+0.76) groups with p=0.001 (p<0.05). In the cerebellum there was ALSO a significant difference in dendritic density between control (7.37+2.23) and treatment groups (3.01+0.64) with p=0.000 (p<0.05).Conclusions: The dendritic density of cerebrum and cerebellum of newborn Rattus norvegicusexposed to 50 percent of food restriction during pregnancy were lower than control.

Causes of post-caesarean surgical site infection at South Konawe Hospital, Southeast Sulawesi, Indonesia, February - July 2017 Mokhamad Anhar Dani; Rizki Pranadyan; Muhammad Yusuf; Budi Prasetyo
Majalah Obstetri dan Ginekologi Vol. 26 No. 3 (2018): December
Publisher : Universitas Airlangga

Objectives: To analyze the causes of post-caesarean section surgical site infection (SSI) at South Konawe Hospital, Southeast Sulawesi, Indonesia, between February and July 2017.Materials and Methods: Retrospective study using descriptive method with cross-sectional design from February to July 2017 in inpatient and outpatient wards at Obstetrics and Gynecology Outpatient Clinic, South Konawe Hospital. The population was the patients medical records.Results: There were nine cases (7.75%) from totally of 116 cases of caesarean section with SSI. Based on SSI type, there were four cases (44.4%) with superficial SSI and 5 cases (55.5%) with deeper classification of SSI. SSI was dominated by women of productive age with age 20-35 years in 66.6% case. The lowest BMI was 22 kg/m2 and the highest BMI was 41.5 kg/m2. Hemoglobin levels were higher than 11 g/dL (66.6%). The most surgical action to be performed was emergency operation in 8 cases (15.09%).Conclusion:Causal characteristics of SSI at South Konawe were age of 20-35 years, the lowest BMI of 22 kg/m2 and the highest BMI 41.5 kg/m2, hemoglobin levels higher than 11 g/dL, and the need of emergency operation.

The effect of sitting and soaking therapy with binahong leaf (Anredera cordifolia) decoction on perineal wound healing Daini Zulmi; Leri Septiani; Suryani Soepardan
Majalah Obstetri dan Ginekologi Vol. 27 No. 1 (2019): April
Publisher : Universitas Airlangga

Objective: To analyze the effect of sitting and soaking therapy with the decoction of Anredera cordifolia on the perineal wound healing in postpartum period mothers.Materials and Methods: The research method used is the Quasi-Experiment with pretest-posttest control group design, a sample of 62 primiparous postpartum period mothers with 2nd-grade perineal rupture. The sampling technique used is purposive sampling to obtain 31 respondents treated by 31 respondents. The wound healing variable was observed using the REEDA scale. The characteristic analysis is tested using Mann-Whitney statistical test, while to test the effect analysis is tested using the Wilcoxon test.Results: The results of this study in the intervention group showed 52.71% was cured after getting treatment for perineal wounds sitting and soaking therapy with the decoction of Anredera cordifolia. On the other hand, in the control group, using only clean water shows 27.90% recovered. Analysis data effect of using the decoction of Anredera cordifolia 25% containing on perineal wound healing showed results with Wilcoxon Test with value (p<0.05).Conclusion: Based on this result there is an effect of sitting and soaking therapy with the decoction of Anredera cordifolia on perineal wound healing for postpartum mothers.

Urogynaecology Training in South East Asia (SEA) and Asia Ng Kwok Weng Roy
Majalah Obstetri dan Ginekologi Vol. 27 No. 1 (2019): April
Publisher : Universitas Airlangga

South East Asia (SEA) is made up of 11 countries (Viet-nam, Laos, Cambodia, Thailand, Myanmar, Malaysia, Singapore, Brunei, Philippines, Indonesia and Timor Leste) from Myanmar in the northwest to Timor Leste in the far south east. It is one of the most far flung region in Asia, with a land mass of 4.5 million km2 and theitspopulation of 641 million makes it the third most populous geographical region in the world after South Asia and East Asia. Asia is the world’s largest most populous continent stretching from the Middle East in the west to Japan in the east with a population of 4.567 billion.

Problem diagnostic of Krukenberg tumor Reza Wangsanagara; Pungky Mulawardhana; Vicky Sumarki; Anny Setijo Rahaju; Tri Wulanhandarini
Majalah Obstetri dan Ginekologi Vol. 27 No. 1 (2019): April
Publisher : Universitas Airlangga

Objectives: to report the case of Krukenberg tumor in 57 years old woman, with complaints of abdominal enlargement since the last 10 months.Case Report: a 57 years old woman, multipara, post menopause, came to our hospital with complaints of enlarging abdomen. Abdominal physical examination showed enlarging abdomen, hard palpable mass, measured 17 cm in diameter, and limited mobility. Abdominal CT result showed solid mass of the right adnexal, expanding to upper right abdomen, omental cake, ascites, and left pleural effusion, right lobe hepatic cyst and multiple bilateral renal cysts. Patient was diagnosed as solid ovarian tumor, suspicious of malignancy. Colonoscopy revealed hemorrhoid interna. Total abdominal hysterectomy with bilateral salpingo-oophorectomy was done. Histopathologic findings showed malignant ovarian tumor, signet ring cell carcinoma of the cervics, endometrium, myometrium, nodule in gastrocolica ligament, and prevesica urinaria nodule. IHC examination of the ovarian tumor showed possible source was of colorectal, supporting the diagnosis of Krukenberg tumor with CK20 (+) and CK7 (-)Conclusion: Krukenburg tumor is a rare ovarian malignancy. Clinical symptoms usually consist of abdominal distension, pain caused by large ovarian mass. Diagnosis of Krukenburg tumor is confirmed by characteristic histologic findings of malignant signet ring cells with cellular stroma. Management for ovarian tumor is surgery removal, with very poor prognosis.

Default sequence of Mozart’s compositions during pregnancy gave higher dendritic density in the cerebrum and cerebellum of Rattus norvegicus offsprings compared with reversed sequence and control Harry Mangasi Binsar Panjaitan; Hermanto Tri Joewono; Widjiati Widjiati
Majalah Obstetri dan Ginekologi Vol. 27 No. 1 (2019): April
Publisher : Universitas Airlangga

Objectives: This study aim to determine sequence of Mozart songs in the analyzing differences in dendritic density of cerebellum and cerebellum of new born Rattus novergicusMaterials and Methods: Experimental study randomized post test only control group design using Rattus norvegicus. Animal subjects were divided into three groups which were control group, and the treatment group that were given exposure to default sequence and reversed sequence of Mozart's music from gestation day 10. We used a comparison test in the analysis expression of BDNF.Results: In the cerebrum there was a significant difference in the Mozart group in reverse rather than with Mozart standard sequence and in standard Mozart group with no exposure group, with p=0.003 and p=0.000. In the cerebellum there was a significant difference in the group in reverse rather than with standard Mozart and in the standard Mozart group with the control group, with p=0.000 and p=0.000. However, there was no significant difference between control group and Mozart group upside down in cerebrum and cerebellum with p=0.109 and p=0.077Conclusion: The density of dendrites in the cerebrum and cerebellum of Rattus norvegicus newborn exposed to Mozart's music during pregnancy with standard Mozart sequence was higher than that in those receiving reverse order and without exposure. There were no significant differences between the density of the cerebrum and cerebellum dendrites between groups exposed to reversed sequence of Mozart composition and those without exposure.

Characteristics of Peripartum Cardiomyopathy (PPCM) pregnancy and preeclampsia in Dr Soetomo Hospital, Surabaya, Indonesia, 2014-2016 Dibya Arfianda; Budi Wicaksono; Khanisyah Erza Gumilar; Andrianto Andrianto
Majalah Obstetri dan Ginekologi Vol. 27 No. 1 (2019): April
Publisher : Universitas Airlangga

Objectives: to present data on the characteristics of pregnancy with PPCM and PE. Management of patients with PPCM is almost the same as for patients with acute or chronic heart failure, which uses drug therapy. PPCM and preeclampsia (PE) are two related diseases, although not directly. Both have similar pathophysiological mechanisms.Case Report: We present 25 pregnancy cases with PPCM at Dr. Soetomo Hospital within 3 years. Data were collected from January 2014 to December 2016, consisting of 5 PPCM cases and the other 20 cases were PPCM with PE cases.Conclusion: Pregnancy with PPCM-PE has higher morbidity than PPCM only. The diagnosis of PPCM should be established immediately if heart failure symptoms are found in the third trimester and the patient has risk factors, such as age >30 years, multigravida, obesity, and multiple pregnancy.

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