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All Journal Journal of Epidemiology and Public Health Indonesian Journal of Medicine Journal of Health Policy and Management Journal of Health Promotion and Behavior Journal of Maternal and Child Health

Setyo Sri Rahardjo

Faculty of Medicine, Universitas Sebelas Maret

Author-ID : 10758193

Medicine & Pharmacology Public Health

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Meta-Analysis the Effect of Malaria Infection on Anemia in Pregnant Women Firdausi Nuzula; Setyo Sri Rahardjo; Bhisma Murti
Journal of Epidemiology and Public Health Vol. 5 No. 4 (2020)
Publisher : Masters Program in Public Health

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (31.091 KB)

Background: Malaria is an important threat to pregnant women, with an increased risk for both mother and newborn, especially in the first and second pregnancies caused by P. falciparum. Malaria infection in pregnant women can cause anemia in the mother and fetus, as well as babies with low birth weight, this can increase maternal and infant mortality rates. This study aims to analyze the magnitude of the influence of malaria infection in pregnant women on the incidence of anemia based on a number of previous similar studies.Subjects and Method: This was a systematic review and meta-analysis carried out by following the PRISMA flow diagram. The process of searching for articles is carried out through a journal database which includes: Google Scholar, PubMed, and Science Direct by selecting articles published in 2010-2020. Key words used include: "malaria infection" AND "pregnancy women" OR "anemia" AND "adjusted odds ratio". The inclusion criteria were full paper articles with observational study design, articles in English, multivariate analysis used with adjusted odds ratios. Articles that meet the requirements are analyzed using the Revmen 5.3 application.Results: A total of seven articles were reviewed in this study with a cross-sectional study design. A meta-analysis of 7 cross-sectional studies showed that malaria infection had a 1.72 times increased risk of anemia in pregnant women compared to those not infected with malaria (aOR 1.72; 95% CI 1.43 to 2.07; p <0.001).Conclusion: Malaria infection increases the risk of anemia in pregnant women.Keywords: malaria infection, pregnancy, anemia, meta-analysisCorrespondence: Firdausi Nuzula. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: ulafn10@gmail.com.Journal of Epidemiology and Public Health (2020), 05(04): 489-498https://doi.org/10.26911/jepublichealth.2020.05.04.11

The Effect of Acupuncture Therapy on Reducing Blood Pressure in Hypertension Patients: Meta-Analysis Faricha Indra Hapsari; Setyo Sri Rahardjo; Hanung Prasetya
Journal of Epidemiology and Public Health Vol. 6 No. 1 (2021)
Publisher : Masters Program in Public Health

Background: Acupuncture is a traditional Chinese medicine for treating ailments, including diseases of the cardiovascular system, such as hypertension. Acupuncture modulates neurohumoral regulatory systems and cardiovascular function. This study aims to estimate the effectiveness of acupuncture therapy in reducing blood pressure in hypertensive patients. Subjects and Method: This was a systematic review and meta-analysis, with PICO, namely Population= hypertension cases aged 20-80 years. Intervention= acupuncture therapy. Comparison= Sham/ Placebo/ No Treatment Acupuncture. Outcome = Blood pressure. The articles used in this study were obtained from several databases including Google Scholar, MEDLINE/ PubMed, Science Direct, Hindawi, BMC, Europe PMC and Springer Link. These articles were collected for 1 month. The keywords to search for articles were as follows: “acupuncture”, “hypertension”, “randomized controlled trial”, “hypertension randomized controlled trial”, “acupuncture randomized controlled trial”, “acupuncture for primary hypertension”, “acupuncture for hypertension essential” AND “acupuncture for blood pressure”. The articles included in this study are full text articles with a randomized controlled trial study design. Articles were collected using PRISMA flow diagrams and analyzed using the Review Manager application (RevMan) 5.3. Results: A total of 9 articles were reviewed in this meta-analysis. Articles are from Boston, Germany, Korea, China, India and Taiwan. The study showed that acupuncture therapy was able to reduce systolic blood pressure with the Standardized Mean Different by 0.54 compared to sham acupuncture /placebo/no treatment (SMD= 0.54; 95% CI= -1.04 to -0.04; p<0.05). Acupuncture reduced diastolic blood pressure 0.49 units (SMD= 0.49; 95% CI= -0.99 to 0.02; p>0.05) compared to sham acupuncture/ placebo, but it was statistically non significant. Conclusion: Acupuncture can reduce systolic blood pressure, but it is less significant in reducing diastolic blood pressure in hypertensive patients.

Meta-Analysis the Effectiveness of Isometric Relaxation and Laser Therapy in Reducing Myofascial Pain Syndrome on Musculus Upper Trapezius Alifiya Zulfa Indana; Setyo Sri Rahardjo; Hanung Prasetya
Journal of Epidemiology and Public Health Vol. 6 No. 2 (2021)
Publisher : Masters Program in Public Health

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (31.704 KB)

Background: Myofascial pain syndrome upper trapezius is a condition of neck pain caused by excessive muscle loading and can occur due to continuous activities with poor posture and ergonomics. There are many interventions that can be given to treat this MPS, such as Post isometric relaxation and laser therapy. This study aims to analyze the effect of post-isometric relaxation and laser therapy on pain reduction in cases of upper trapezius myofascial pain syndrome.Subjects and Method: This study is a syste

Mortality and Severity of COVID-19 Patients with Chronic Obstructive Pulmonary Disease: A Meta-Analysis Atika Mima Amalin; Setyo Sri Rahardjo; Hanung Prasetya
Journal of Epidemiology and Public Health Vol. 6 No. 3 (2021)
Publisher : Masters Program in Public Health

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (31.344 KB)

Background: COVID-19 has become a pandemic in all countries including Indonesia. The death rate from COVID-19 is concentrated in elderly patients and those with comorbidities. COPD is one of the comorbidities that can worsen and even cause death. COPD ranks in the top 3 leading causes of death in the world causing 2.3 million deaths in 2019. This study aims to analyze the effect of COPD comorbidities on mortality and severity of COVID-19 patients.Subjects and Method: This study used a systematic review and meta-analysis by following the PRISMA flow chart. Search articles through journal databases, namely: Google scholar, PubMed, Science Direct and Link Springer. The articles search was done by considering the eligibility criteria defined in the PICO model. P= COVID-19 patient; I= COPD participant; C= without COPD; O= need for mechanical ventilation, ICU admission, and death. Inclusion criteria were cohort full paper articles, in English, multivariate analysis with adjusted Odds Ratio. Articles analyzed with RevMan 5.3.Results: The 13 cohort study designs reviewed with a meta-analysis to estimate the risk of death showed that comorbid COPD increased the risk of death (aOR= 1.33; 95% CI= 1.08 to 1.64; p= 0.007). 9 cohort study designs were reviewed with a meta-analysis to estimate the risk of severity with indicators of mechanical ventilation need (aOR= 1.38; 95% CI= 1.05 to 1.82; p= 0.020). 7 cohort study designs were reviewed by meta-analysis to estimate the risk of severity with indicators of risk of ICU admission (aOR= 1.25; 95% CI= 1.04 to 1.50; p= 0.020).Conclusion: COPD comorbidities increase the risk of need for mechanical ventilation, ICU admission and death among COVID-19 patients.Keywords: COVID-19, COPD, death, severityCorrespondence:

The Use of Insecticide Mosquito Nets and Insecticide Spraying on the Risk of Malaria in Children: A Meta-Analysis Arlina Azka; Setyo Sri Rahardjo; Bhisma Murti
Journal of Epidemiology and Public Health Vol. 6 No. 3 (2021)
Publisher : Masters Program in Public Health

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (31.896 KB)

Background: Malaria is a vector-borne disease caused by Plasmodium infection and there are more than 30 species of Anopheles which are important vectors of malaria. The main interventions recommended for controlling malaria vectors are the use of insecticide mosquito nets and indoor residual spraying. This study aims to estimate the effect of using insecticide mosquito nets and spraying insecticides on the risk of malaria in children.Subjects and Method: This was a meta-analysis study using PRISMA flow diagram guidelines. Article searches were carried out in the PubMed, Google Scholar, Science Direct, ResearchGate, and SpringerLink databases with the keywords

A Meta-Analysis of Correlations between Chronic Obstructive Pulmonary Disease, Smoking, and Severity of COVID-19 Gigih Cita Pambudi; Setyo Sri Rahardjo; Sumardiyono Sumardiyono
Journal of Epidemiology and Public Health Vol. 6 No. 4 (2021)
Publisher : Masters Program in Public Health

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Background: Corona Virus Disease 2019 (COVID-19) is a respiratory disease that can progress to severe hypoxemia with cases reaching more than 235 million cases worldwide until November 2021. The association with Chronic Obstructive Pulmonary Disease (COPD) and smoking habits are both very common globally and may increase the severity of COVID-19. However, it has not been elucidated. Given the gaps in evidence and the increasing prevalence of COVID-19, this study aimed to examine the influence of COPD and smoking habits on the severity of COVID-19 patients.Subjects and Method: This meta-analysis study was conducted with PICO as follows: Popula

Pesticide Exposure and Its Correlation with Hemoglobin and Cholinesterase in Farmers Who Used Pesticide Arum Nuryati; Setyo Sri Rahardjo; Bhisma Murti
Journal of Epidemiology and Public Health Vol. 7 No. 3 (2022)
Publisher : Masters Program in Public Health

Background: Agriculture is the most important sector in basic human needs. Farmers must improve the quality of agricultural products by using synthetic chemicals, someone who experiences pesticide poisoning will have low cholinesterase levels. This study aims to analyze pesticide exposure to hemoglobin and cholinesterase levels in farmers who use pesticides.Subjects and Method: This was a systematic review study and meta-analysis conducted with the PRISMA diagram guidelines. The search for articles was carried out taking into account the eligibility criteria defined in the PICO model. Population= farmers using pesticides, Intervention= exposed to pesticides, Comparison= not exposed to pesticides, Outcome= hemoglobin and cholinesterase levels. The article search process was carried out between 2002-2022 from the Pubmed, Science Direct, Google Scholar, Springer Link, Hindawi, and Plose one databases. The keywords used were “hemoglobin”, “exposed pesticide”, “cholinesterase level”, “farmers”, “hemoglobin AND exposed pesticide”, “cholinesterase level AND farmers”, “hemoglobin AND farmers”. The inclusion criteria in this study were the full text of a cross-sectional study, discussing pesticide exposure to hemoglobin and cholinesterase levels in farmers using pesticides, published in English. Final results are presented in the mean SD of the multivariate analysis. Data analysis was performed using RevMan 5.4 software.Results: A meta-analysis was conducted on 13 articles originating from America, Asia, Africa, and Europe. The results of the meta-analysis showed that farmers exposed to pesticides experienced a decrease in hemoglobin, but it was not statistically significant (SMD= -0.28; 95% CI= -1.10 to 0.54; p=0.500). Pesticide exposure reduced cholinesterase levels in farmers using pesticides, the results were statistically significant (SMD= -2.48; 95% CI= -3.68 to -1.27; p<0.001).Conclusion: The results of the meta-analysis showed that pesticide exposure decreased hemoglobin and cholinesterase levels in farmers using pesticides. Keywords: hemoglobin, cholinesterase levels, farmers Correspondence:Arum Nuryati. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: arumnuryati@student.uns.ac.id. Mobile: +6285728792097

Meta-Analysis: The Effect of D-Dimer on Mortality in Patients with COVID-19 Yusuf Ryadi; Setyo Sri Rahardjo; Burhannuddin Ichsan
Journal of Epidemiology and Public Health Vol. 7 No. 4 (2022)
Publisher : Masters Program in Public Health

Background: The severity of COVID-19 can be detected by examining elevated levels of CRP, ferritin, IL-6 and LDH. Elevated D-dimer levels are often found in patients with severe COVID-19 which can predict the occurrence of ARDS (Acute Respiratory Distress Syndrome) and patient mortality. The purpose of this study was to determine how much influence D-dimer levels had on mortality of COVID-19 patients. Subjects and Method: This study used a systematic review and meta-analysis with following PICO, population: patients with a clinical diagnosis of COVID-19. Intervention: high D-dimer level. Comparison: low D-dimer level. Outcome: mortality. The data used were obtained from scientific research articles from Pubmed, Google Scholar, Science Direct, and Proquest electronic databases with a cohort design in 2020 until 2022 and report on aOR in multivariate analysis. The keywords used in the search for scientific articles were “D-dimer level” OR “D-dimer” AND “COVID-19” AND “mortality”. The selection of articles is done by using PRISMA flow diagram. Data were analyzed using Review Manager software version 5.4.1.Results: A total of 12 studies with a cohort design that met the criteria from Asia, America, and Europe were selected for a systematic review and meta-analysis. Based on the meta-analysis, it was found that increased levels of D-dimer (>0.5 g/mL) increased mortality in COVID-19 patients by 6.40 times compared to low levels of D-dimer (≤0.5 g/mL) and was statistically significant (aOR = 6.40; 95% CI= 4.51 to 9.08; p<0.001).Conclusion: Elevated levels of D-dimer may increase mortality risk in COVID-19 patients. Keywords: d-dimer level, d-dimer, covid-19, mortality. Correspondence:Yusuf Ryadi. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Jawa Tengah. Email: yusuf.ryadi@gmail.com. Mobile: 085715605268.

Meta-Analysis: The Effect of Vaccination on the COVID-19 Infection Farida Nurhayati; Setyo Sri Rahardjo; Bhisma Murti
Journal of Epidemiology and Public Health Vol. 8 No. 1 (2023)
Publisher : Masters Program in Public Health

Background: The Indonesian government has determined that COVID-19 is a public health emergency and a non-natural national disaster that requires multi-strategy management. Strategies such as implementing health protocols and vaccination efforts to break the chain of transmission of COVID-19 must continue to be carried out massively. This study aims to analyze the effect of vaccination on COVID-19 infection.Subjects and Method: This study is a systematic review and meta-analysis, with PICO as follows Population= population aged ≥18 years. Intervention= Vaccination. Comparison= Not vaccinated. Outcome= COVID-19 infection. The articles used in this study were obtained from several databases including PubMed, Google Scholar, and Scopus. These articles were collected over 2 months. The keywords to search for articles are as follows “Vaccine OR Vaccination AND (Infection OR Trans-mission) AND COVID-19 OR SARS-CoV-2”. The articles included in this study were full-text articles with a retrospective or prospective cohort study design. Articles are collected using PRISMA flow diagrams. Articles were analyzed using the Review Manager 5.3 application.Results: A total of 10 articles reviewed in this meta-analysis study originating from England, Spain, France showed that COVID-19 vaccination is effective in reducing the risk of COVID-19 infection. People who were given the COVID-19 vaccine had a 0.22 times risk of being infected compared to those who were not vaccinated, and the reduced risk was statistically significant (aHR= 0.22; 95% CI= 0.13 to 0.36; p <0.001).Conclusion: COVID-19 vaccination is effective in reducing the risk of COVID-19 infection. Keywords: vaccination, infection, COVID-19, SARS-COV-2 Correspondence:Farida Nurhayati. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java, Indonesia. Email: faridafay19@gmail.com. Mobile: +6285642154353.

Meta-Analysis the Effects of Rotavirus Vaccine, Exclusive Breastfeeding, and Maternal Education on Diarrhea in Children Under Five Genn Andrean Pratama; Setyo Sri Rahardjo; Bhisma Murti
Journal of Epidemiology and Public Health Vol. 8 No. 3 (2023)
Publisher : Masters Program in Public Health

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/jepublichealth.2023.08.03.02

Background: Diarrhea is an infectious disease that can cause death in children under five years. Diarrheal disease is a disease with the highest mortality and morbidity after pneumonia. The purpose of this study was to analyze and estimate the effect of rotavirus vaccine, exclusive breastfeeding, and mother's education level on the incidence of diarrhea in toddlers, with a meta-analysis based on previously conducted primary studies. Subjects and Method: This article was prepared using a systematic review and meta-analytic study. This research was conducted using the PICO model. Meta-analytic studies were conducted by searching for articles from databases in electronic form using PubMed, Google Scholar, Sciencedirect, and Springer Link. Article searches were conducted from 1-28 February 2023. The keywords used were “Vacinnation” OR “Exclusive breastfeeding” OR “Educational Mother” OR “Infection” OR “Diarrhea Childhood”. The inclusion criteria for this study were complete articles using cross-sectional research, published years from 2013-2022. Analysis of the articles used RevMan 5.3 software. Results: A total of 24 cross-sectional studies from Africa and Asia were selected for systematic review and meta-analysis. The results of the meta-analysis showed that not given rotavirus vaccine had a 3.60 times the risk of experiencing diarrhea compared to those given rotavirus vaccine (aOR= 3.60; 95% CI= 2.31 to 5.64; p<0.001), not given exclusive breastfeeding had a risk of experiencing diarrhea 3.28 times compared with those who were given exclusive breastfeeding (aOR= 3.28; 95% CI= 2.24 to 4.80; p<0.001), and children who had mothers with low education levels had a 2.08 times higher risk of experiencing diarrhea compared to children who had mothers with low education levels which is higher (aOR= 2.08; 95% CI= 1.71 to 2.54; p<0.001). Conclusion: Not being given the rotavirus vaccine, not being given exclusive breastfeeding, and the mother's low education level are at risk of increasing the incidence of diarrhea in toddlers. Keywords: rotavirus vaccine, exclusive breastfeeding, mother's level of education, child diarrhea Correspondence: Genn Andrean Pratama. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java, Indonesia. Email: andreanpratama0077@gmail.com. Mobile: +6282278467441.

Co-Authors Afriza Umami Agus Kristiyanto Agustaria Budinugroho Alifiya Zulfa Indana Ambar Mudigdo Ambar Sari Anindita Hasniati Rahmah Arlina Azka Arum Nuryati Atika Febri Anggriani Atika Mima Amalin Atika Nikmah Aulia Noorvita Ramadani Ayu Laela Fitriyani Azura Arisa Bhisma Murti Bhisma Murti Bhisma Murti Bhisma Murti Bhisma Murti Bhisma Murti Bhisma Murti Bhisma Murti Burhannuddin Ichsan Danti Narulita Dian Surya Kartika Diana Sayidah Dono Indarto Dwi Kurniawati Eka Siti Chasanah Endang Sutisna Sulaeman Erick Zicof Eti Poncorini Pamungkasari Faricha Indra Hapsari Farida Nurhayati Febry Istyanto Firdausi Nuzula Firman Pardosi Gabriela Advitri Febriani Genn Andrean Pratama Gigih Cita Pambudi Hanung Prasetya Hanung Prasetya Hanung Prasetya Hanung Prasetya Hanung Prasetya Hanung Prasetya Harsono Salimo Hermanu Joebagio Herry Putut Cahyono Ika Sumiyarsi Sukamto Ika Sumiyarsi Sukamto Isna Qadridjati Isna Qadrijati Khairina Nur Hidayati Lailatul Rohmah Lidia Aditama Putri Lusia Arina Cahyaningrum Maria Regina Tri Yonita Maya Ayu Riestiyowati Muh. Syaiful Akbar Muhibbah Fatati Natalino de Jesus Varela Niken Kartika Sari Ninik Hartini Ninil Dwi Pangestu Nisrina Nafisa Nur Isniani Ningsih Nurul Ulya Luthfiyana Okid Parama Astirin Pawito Pawito Philipus Prihantiko Kurniagung Puspita Mayangsari Prabowo Putri Pamungkas Putu Anggi Widia Karmany RB Soemanto Retno Sulistyani Revi Gama Hatta Novika Revi Gama Hatta Novika Revi Gama Hatta Novika Ristamaya Danar Dewi Rizki Kurniawan Saputra Ruben Dharmawan Satriyo Fajar Wicaksono Sri Mulyani Sumardiyono Sumardiyono Sumardiyono Sumardiyono Tri Godha Fitriani Victoria Husadani Permata Sari Vitri Widyaningsih Yola Alqorien Mustikarani Yovita Eka Ratna Kumala Yulia Lanti Retno Dewi Yulia Lanti Retno Dewi Yusuf Ryadi

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