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All Journal Health and Medical Journal KRTHA BHAYANGKARA Jurnal Akuntansi Dan Bisnis Indonesia (JABISI) Jurnal Ilmu Hukum, Humaniora dan Politik (JIHHP) Jurnal Riset Rumpun Ilmu Kedokteran (JURRIKE) Journal of Indonesia Vascular Access Jurnal MedScientiae Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education and Research Institute Prosiding Seminar Nasional COSMIC Kedokteran Jurnal Widya Medika
Kartika, Ronald Winardi
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Physics Public Health Veterinary

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Journal : jurnal medscientiae

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Evaluasi Mikrovaskuler dengan Near Infrared Spectroscopy pada Pasien Kaki Diabetes Kartika, Ronald Winardi; Timotius, Kris Herawan
Jurnal MedScientiae Vol. 3 No. 1 (2024): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i1.3074

Abstract

Peripheral Arterial Disease (PAP) requires good evaluation to reduce amputation rate. The aim of this study is to assess non-invasive detection methods in evaluating microvascular conditions in PAP. The potential use of Near Infrared Spectroscopy (NIRS) in identifying disorders in patients with PAP, either with or without DM, was also assessed. A systematic literature search was conducted through PUBMED until October 2023. Based on the literature review, it can be concluded that the use of NIRS in evaluating microvascular status in PAP is a non-invasive testing method that has expanded its role. Evaluation with NIRS provides metrics such as recovery time, deoxygenation, oxygen consumption (VO2), tissue oxygen saturation (StO2), total haemoglobin (HbT), and oxyhemoglobin area under the curve (O2 HbAUC). NIRS also has the potential to assist multidisciplinary teams in treating high-risk patients, especially in diabetic patients whose symptoms are compensated by peripheral neuropathy. This study shows that NIRS can be used as a useful tool in evaluating microvascular status in PAP, by providing important information that can be used to optimise patient care and prevent more serious complications. It is concluded that NIRS can be used as a tool to evaluate the effectiveness of treatment and prevent worsening of the condition of patients with PAP in diabetic foot.
Potensi Sekretom Mesenchymal Stem Cell pada Terapi Regeratif Penyakit Paru Fibrosis Kartika, Ronald Winardi; Timotius, Kris Herawan
Jurnal MedScientiae Vol. 3 No. 2 (2024): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i2.3142

Abstract

Fibrosis lung diseases such as chronic obstructive pulmonary disease, acute lung injury and post-Covid 19 fibrosis lung disease are considered as major health problems in the last decade. Cellular therapy with Mesenchymal Stem Cells (MSC) offers a novel therapeutic approach for fibrosis lung disease associated with anti-inflammatory, immunomodulatory, regenerative, pro-angiogenic and anti-fibrotic properties. Such therapeutic effects may be attributed to the MSC-secretome, which is made of free soluble proteins and extracellular vesicles (EVs). This review summarises some recent literature findings related to the efficacy and safety of MSC-derived products in pre-clinical models of lung diseases, demonstrating the biologically active substances contained in the MSC-secretome and its mechanisms involved in tissue regeneration. A perspective view is given on the secretome being a high-quality, safe and effective medicinal product,  
Co-Authors Atmaja, Yuvensius Gerry Chrispian Oktafbipian Mamudi, Chrispian Oktafbipian Diana Frederica Dwiyanti, Hapsari Erma Mexcorry Sumbayak Eva Oktavini Gisela, Esther Goh, Daniel Gosal, Darren Gracienne hartanto hartanto Hasan, Afrizal Ignatio R. Haryono Irsan Hasan Kris Herawan Timotius Kristianto, Jason Renaldi Liem, Jen Fuk Nasser, M Nasser, M. Pasa, Muhamad Alvin Putra Sartika, Chyntia Retna Sartika, Katarina Dewi Siufui Hendrawan Soni, Yulfitra Suparto Suparto Supriyanto, Jaya Suradji, Eka Widrian Susanti, Yosephin Sri Sutanti, Yosephin Sri Tena Djuartina, Tena Tendean, Marcel Tri Agus Suswantoro Veronika Maria Sidharta Widjaja, Daniel Wijaya, Wendy Octantia Winata, Susanti Dewi Yohanes Firmansyah Yong, Bernard Jonathan Christian Yoshua, Edwin