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All Journal Hemera Zoa Jurnal Veteriner Damianus Journal of Medicine Jurnal Kedokteran Anatomica (Anatomica Medical Journal) Health and Medical Journal SANITAS: Jurnal Teknologi dan Seni Kesehatan Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Makara Journal of Health Research Jurnal Riset Rumpun Ilmu Kedokteran (JURRIKE) The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Journal of Urban Health Research Mitramas Jurnal Pengabdian dan Pemberdayaan Masyarakat Mitramas Jurnal Pengabdian dan Pemberdayaan Masyarakat
Tena Djuartina, Tena
Departemen Anatomi, Fakultas Kedokteran Dan Ilmu Kesehatan Unika Atma Jaya
Biochemistry, Genetics & Molecular Biology Dentistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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PCS-5 Nitric Oxide Induced Basal Cell Hyperplasia and Lamina Propria Elongation in Rat Gastroesophageal Junction Tena Djuartina; Bambang Pontjo Priosoeryanto; Ari Fahrial Syam; Ahmad Aulia; Tri Isyani Tungga Dewi
Hemera Zoa Proceedings of the 20th FAVA & the 15th KIVNAS PDHI 2018
Publisher : Hemera Zoa

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (582.843 KB)

Abstract

NO (Nitric Oxide) is an inorganic compound composed of nitrogen and oxygen, NO is also produced in various places on various types of mammalian cells. NO as a radical compound is important in mediating physiological and pathological events in mammals including humans [1].GEJ (gastroesophageal junction) is a transition zone between the surface of esophagus which is covered by stratified squamous epithelium to the gastric mucosa which consists of simple columnar epithelium (z-line), where circular muscle of esophagus fuse with oblique muscle and lipid layer of the gaster. At the lower part of GEJ, there is the lower esophageal sphincter (LES) that not only allow food to move into stomach and works as an exit passage of the gas, but also inhibit reflux of any substances that potentially can cause harm to the esophagus [2].Petersson et al, found that chronic exposure to cytotoxic levels of NO can cause inflammation, intestinal metaplasia and neoplasia. Although it is known that gastric acid, pepsin and bile acids can cause adenocarcinoma of distal esophagus and GEJ, NO exposure and nitrosative stress role in this phenomenon is yet to be fully understood and further study is needed [3].The purpose of this was to identify and compare the histopathological changes occurring in GEJ in relation to administration of physiological concentration of nitrate dissolved in HCl and ascorbic acid. As such, the animal model used in this study can be used to study and represent the changes microscopically, because obtaining a full thickness biopsy from a human subject can be difficult to perform.
ASAP ROKOK KONVENSIONAL DAN ELEKTRONIK MEMBERIKAN GAMBARAN KERUSAKAN STRUKTUR ALVEOLUS YANG SAMA Jenny Lauvita; Tena Djuartina; Dyonesia Ary; Iskandar Rahardjo Budianto; Robi Irawan
Bahasa Indonesia Vol 21 No 1 (2022): Damianus Journal of Medicine
Publisher : Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/djm.v21i1.2093

Abstract

Introduction: Cigarettes have become the cause of health problems and even death, especially in developing countries like Indonesia. Cigarettes contain various free radical components for the body, thereby increasing inflammation in various organs and tissues, especially the lungs. This will trigger proteolysis so that the alveoli lose elasticity. Electronic cigarettes are then introduced as an alternative to reduce smoking. However, there has been not enough research conducted on their safety and long-term effects of e-cigarettes, so researcher aim to compare the impact of conventional and electronic cigarettes on alveolar damage. Methods: This research was conducted experimentally, using 30 male Sprague Dawley rats aged 10-12 weeks and weighing 150-250 grams as sample. These rats were necropsed after being exposed to cigarettes smoke and e-cigarettes vapor for 2 weeks and 4 weeks to make lung tissue preparations with HE staining. These preparations were observed under a microscope to measure the degree of alveolar damage based on the edema, alveolar septal destruction, and inflammatory cell infiltration. Finally, the data was analyzed using Kruskal-Wallis followed by one-Mann-Whitney statistical tests with STATA. Results: Rats exposed to conventional cigarette smoke and e-cigarette vapor in the second week already showed significant alveolar damage compared to the control group. (p<0.05). However, there was no significant difference between exposure for 2 weeks and 4 weeks. (p>0.05) Between rats given conventional cigarette smoke and electronic cigarette vapor, there was no significant difference in degree of alveolar damage at week 2 and week 4. (p>0.05) Discussion: As a result, both conventional cigarette smoke and e-cigarette vapor have the same effect on alveolar damage. This is because both conventional cigarette smoke and e-cigarette vapor contain nicotine which will trigger the release of fibronectin so that it can trigger fibrosis in the lung parenchyma. In addition, the carbon monoxide contained in both can inhibit fibroblast proliferation and damage the elastin in the alveolar wall, so that the alveoli lose its elasticity and tend to expand. Keywords: Lung inflammation, cigarettes effect on lungs, e-cigarettes, tobacco cigarette, lung damage
KORELASI KEKUATAN GENGGAMAN TANGAN DENGAN KARAKTER ANTROPOMETRI LENGAN BAWAH DAN TANGAN SERTA INDEKS MASSA TUBUH Heidy Heidy; Tena Djuartina; Robi Irawan
Bahasa Indonesia Vol 18 No 1 (2019): Damianus Journal of Medicine
Publisher : Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/djm.v18i1.2189

Abstract

Introduction: An individual’s overall muscle strength is commonly assessed by a power grip measurement, a reliable indicator of functional capacity and physical condition. The development of muscle parallels the changes of body composition during growth. Aim of this study is to examine the correlationship between hand grip strength and anthropometric. Methods: This cross-sectional study involved 76 male students of Dhammasavana School, aged between 12 – 16 years old, North Jakarta. Hand grip strength was examined using a digital dynamometer on the dominant side. Statistical analysis was computed using SPSS ver. 15.0 program with Spearman correlations test. Significance was set at p<0.05. Results: Dominant hand grip strength was found to have significant (p<0.05 - 0.001) positive correlation with height (r=0.612), lower arm muscle-and-bone cross-sectional circumference and area (CSA) (r=0.553 and r=0.553 respectively), hand length (r=0.548), forearm length (r=0.540), age (r=0.520), weight (r=0.416), and forearm girth (r=0.376). Conclusion: No significant correlation between grip strength and body mass index was found. Positive correlations between the variables mentioned above conclude that the higher the value of the anthropometric measurements, the greater the strength generated in a power grip.
Differences in Children’s Nutritional Knowledge Level and Parent’s Characteristics in Obese and Non-Obese Adolescents of Permai Pluit Junior High School Tena Djuartina; Sylvia Wijaya; Andreas Steven; Syarief Darmawan
SANITAS: Jurnal Teknologi dan Seni Kesehatan Vol 11 No 2 (2020): SANITAS Volume 11 Nomor 2 Tahun 2020
Publisher : Politeknik Kesehatan Kemenkes Jakarta II

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36525/sanitas.2020.17

Abstract

Obesity is a major health problem among children. The etiology of childhood obesity is multifactorial and it leads to many complications in adulthood.This study aimed to assess the differences in nutritional knowledge and characteristics of parents in obese and non-obese adolescents. This case control descriptive research was conducted on all students of Permai Pluit Junior High School and their parents. Nutritional knowledge and characteristics of parents were obtained by self-report using a questionnaire. The weight and height of the subjects were measured according to standard methods and body mass index was calculated, then assessed with CDC growth charts. Data were analyzed using chi square, Kolmogorov Smirnov, and Fisher Exact test; significance level was set at 0.05. The prevalence of obesity was 18.21%. There was no significant relationship between nutritional knowledge of parents and nutritional status of adolescent (p = 0.750). There was also no significant relationships between characteristics of parents and nutritional status of adolescents (mothers’ education, p = 0.907; fathers’ education, p = 0.203, mothers’ occupation, p = 0,627, fathers’ occupation, p = 0.151). In conclusion, there is no relationship between neither nutritional knowledge nor characteristics of parents and nutritional status of adolescents.
The Difference Of Physical Activity In Obese And Non-Obese Adolescents Of Permai Pluit Junior High School Students Tena Djuartina; Andreas Steven; Sylvia Wijaya; Syarief Darmawan
SANITAS: Jurnal Teknologi dan Seni Kesehatan Vol 11 No 2 (2020): SANITAS Volume 11 Nomor 2 Tahun 2020
Publisher : Politeknik Kesehatan Kemenkes Jakarta II

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36525/sanitas.2020.15

Abstract

The Difference Of Physical Activity In Obese And Non-Obese Adolescents Of Permai Pluit Junior High School Students Obesity is defined as abnormal or excessive fat accumulation that presents a risk to health. According to the World Health Organization (WHO), at least 2.8 million people die every year as a result of being obesity. The prevalence of obesity in women is higher (26.9%) than males (16.3%) and according to RISKESDAS (2013) showed that the prevalence of obesity in adolescents, aged 13-15, in Indonesia amounted to 2.5%. The aim of this study is to assess the differences of physical activity in obese and non-obese adolescents. The design of this research is descriptive analytical research with case control categorical approach. The sample is the entire of Permai Pluit Junior High School student. The level of physical activity is assessed by using the Baecke Questionnaire, which has been modified and is statistically analyzed using Chi square test with Fischer Exact for an alternative test. All students in Permai Pluit Junior High School have varying levels of activity. The obese students in Permai Pluit Junior High School are amounted to 14.44% and there is significant difference between physical activity and nutritional status (p = 0.011). The level of physical activity that is most often committed by the girl students is medium intensity (34,12%) as well as by the boy students is severe intensity (25,98%). Conclusion there is significant difference between physical activity and nutritional status among adolescents of Permai Pluit Junior High School students.
A Comparative Study on Different Effects and Exposure Duration Between Conventional Cigarette Smoke and Electronic Cigarette Vapor on Serum Interleukin-1? Level: An In Vivo Study Vienna Christantia; Iskandar Rahardjo Budianto; Tena Djuartina; Maria Dara Novi Handayani
Jurnal Veteriner Vol 23 No 2 (2022)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (98.053 KB) | DOI: 10.19087/jveteriner.2022.23.2.252

Abstract

Smoking is known to have bad effects on health. People start using e-cigarettes with the assumption that e-cigarettes are safer, but the safety of e-cigarettes is still in doubt. Harmful substances from cigarettes can trigger an increase in free radicals and induce inflammatory process. The aim of this study was to evaluate and compare the increase of serum Interleukin-1? due to exposure to conventional cigarette smoke and e-cigarette vapor based on exposure time. This study was conducted experimentally on 30 male white rats Sprague Dawley strain. The rats were divided into five treatment groups (control group, two and four weeks of exposure to conventional cigarette smoke, and two and four weeks of exposure to electronic cigarette vapor). Smoking session was given once a day. The rats were sacrificed then necropsied and Interleukin-? levels were calculated using the enzyme linked immunosorbent assay (ELISA) Kit. The data obtained were analyzed using one-way analysis of variance (ANOVA) statistical test. Exposure to conventional cigarette smoke and e-cigarette vapor did not give any significant changes to Interleukin-1? level in rats, both at two weeks and four weeks of exposure. However, there was a tendency of increased Interleukin-1? levels with increasing time. This tendency is more obvious in groups with exposure to conventional cigarette.
Teknik Pembuatan Tikus Model untuk Abnormalitas dari Gastroesophageal Junction (GEJ) Tena Djuartina; Ahmad Aulia; Bambang Pontjo Priosoeryanto; Tri Isyana Tungga Dewi; Ari Fahrial Syam
ANATOMICA MEDICAL JOURNAL | AMJ Vol 5, No 3 (2022)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/amj.v5i3.12102

Abstract

Nitrit oksida (NO) adalah salah satu molekul terkecil yang termasuk radikal. Ketika nitrit saliva memasuki lambung terjadi kombinasi asiditas asam askorbat dari asam lambung yang merubah nitrit menjadi NO. Konsentrasi NO intraluminal maksimal pada gastroesophageal junction (GEJ) dan daerah kardia sehingga dapat mengakibatkan stress nitrosatif. Tujuan: mempelajari patofisiologi NO terhadap abnormalitas sfingter GEJ. Metode: menggunakan 48 ekor tikus putih jantan galur Wistar, dikelompokan menjadi 1 kelompok kontrol dan 3 kelompok perlakuan berdasarkan dosis natrium nitrit (NaNO3) dan waktu nepkrosi. Semua kelompok perlakuan diberikan 1 ml HCl dan 1 ml asam askorbat dengan sonde pada bagian bawah GEJ dan kelompok kontrol hanya diberikan 1 ml aquabidest steril. Kemudian dilakukan pemeriksaan NO luminal, NO jaringan, pemeriksaan morfologi untuk mengetahui gambaran makroskopis daerah GEJ, gambaran mikroskopis pada densitas pleksus Meissner dan pleksus Auerbach, menilai terjadinya perpanjangan lamina propria dan menganalisis serbukan sel radang limfosit. Hasil: didapatkan nepkrosi hari kedua terdapat korelasi antara NO jaringan dan perpanjangan lamina propria didapat nilai r=-0.630 dengan nilai p<0.05, serta korelasi antara perpanjangan lamina propria dengan limfosit nilai r = 0.590 dengan nilai p<0.05. Pada terminasi hari ke-8 terdapat korelasi antara NO luminal dan densitas sel saraf pleksus Meissner dan pleksus Auerbach dengan nilai r = 0.758 dan nilai p <0.05. Kesimpulan: Pemberian senyawa NO3 meningkatkan kadar NO luminal yang menyebabkan terjadinya perubahan morfologi makro-mikroskopis, inflamasi serta peningkatan densitas sel saraf pada pleksus Meissner dan pleksus Auerbach di daerah sfingter GEJ.Kata kunci: GEJ, GERD, NO
Korelasi antara Berat Badan, Tinggi Badan, Indeks Massa Tubuh dan Rasio Lingkar Pinggang-Panggul dengan Hiperkifosis Torakal dan Hiperlordosis Lumbar pada Pelajar Sekolah Menengah Atas Tena Djuartina; Andrew Wijaya; Nawanto Agung Prastowo; Sylvia Wijaya
Majalah Kedokteran Indonesia Vol 70 No 8 (2020): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.70.8-2020-257

Abstract

Background: Adolescents’ lifestyle has been changing overtime, impacting their body weight, height, body mass index, and waist hip ratio. This changes also outgrow with the changes of sagittal curvature of thoracic kyphosis and lumbar lordosis. Thoracic hyperkyphosis and lumbar hyperlordosis is a disease not only affecting convenience, but also psychologically impacted (body image disorder). The only way to stop this is by aiming for preventive measure, by knowing the correlation between these variables to thoracic hyperkyphosis and lumbar hyperlordosis.Method: A cross sectional study was conducted in two schools, SMAN 2 Jakarta and SMA Katolik Diakonia. This study used weight scales to measure body weight and scaled-tape to measure body height. The sagittal curvature was measured by flexicurve.Result: Out of 154 respondents, 49.35 % were male students and the rest 50.65% were female students. Hyperkyphotic students were found 24.68%, and hyperlordotic students were found 24.02%. No correlation was found between variables but IMT to lumbar hyperlordosis. Weak correlation also found between waist and hip circumference and lumbar hyperlordosis.Conclusion: Weak correlation was found between Body Mass Index (BMI) and lumbar hyperlordosis in high school students. No correlation found between waist-hip ratio and lumbar hyperlordosis, but weak correlation was found between waist and hip circumference and lumbar hyperlordosis. No correlation was found between variables and thoracic hyperkyphosis.
Cavum septi pellucidi and cavum vergae cyst in man Sasmita, Poppy Kristina; Djuartina, Tena
Bahasa Indonesia Vol 10 No 2 (2011): Damianus Journal of Medicine
Publisher : Atma Jaya Catholic University of Indonesia

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Abstract

Introduction: The cavum septi pellucidi (CSP) and cavum vergae (CV) are cystic anomalies of septum pellucidum. Case: A 30-year-old man, which revealed cavities at the anatomical location of the CSP and CV on brain magnetic resonance imaging (MRI) because of recurrent headache. Conclusions: The CSP and CV occur during the developmental process of the brain which regresses between the seventh month of intrauterine life and the second year of postnatal life. Persistence of these structures does not cause any symptoms, but sometimes related to malformations and psychiatric disturbances, mainly dependent on size. In this case, developmental disturbance is the underlying cause.
CAROTID ARTERY INTIMA-MEDIA THICKNESS IN HEALTHY YOUNG INDIVIDUALS Sasmita, Poppy Kristina; Uinarni, Herlina; Djuartina, Tena
Bahasa Indonesia Vol 12 No 1 (2013): Damianus Journal of Medicine
Publisher : Atma Jaya Catholic University of Indonesia

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Abstract

Latar Belakang: Ketebalan tunika intima-media (IMT) arteri karotis merupakan prediktor independen terhadap kejadian penyakit vaskular. Tujuan: Penelitian ini bertujuan untuk menilai IMT arteri karotis dewasa muda dengan menggunakan ultrasonografi. Metode: Pengukuran IMT arteri karotis dilakukan dengan ultrasonografi B-mode di proksimal arteri carotis komunis kedua sisi pada 136 dewasa muda. Dilakukan pemeriksaan tekanan darah, berat badan, indeks massa tubuh, profil lipid, dan kadar glukosa darah untuk menyingkirkan faktor risiko. Hasil: Total terdapat 74 orang, rerata berusia 18,11 tahun, dan tidak memiliki faktor risiko yang terkait dengan aterosklerosis. Nilai IMT arteri karotis lebih tinggi pada laki-laki dan berbeda antara sisi kiri dan kanan (0,659 vs 0,612 mm dan 0,675 mm vs 0,648 mm). Rerata IMT arteri karotis 0,646±0,14 mm. Kesimpulan: Pengukuran IMT karotis penting untuk memprediksi kejadian vaskular di masa depan. Kami berharap hasil ini dapat digunakan sebagai data dasar untuk penelitian selanjutnya dalam mendeteksi proses aterosklerosis yang asimtomatik.
Co-Authors ., Vetinly Ahmad Aulia Ahmad Aulia Alfred Sutrisno, Alfred Andreas Steven Andrew Wijaya Ari Fahrial Syam Ari Fahrial Syam Bambang Pontjo Priosoeryanto Blandina, Maria Bernadetta Nadya Budianto, Iskandar R. Chandra, Valencia Dion Notario Dyonesia Ary Erfen Gustiawan Suwangto, Erfen Gustiawan Gosal, Ervina Heidy Heidy Herlina Uinarni Ignatio R. Haryono Irawan, Robi Iskandar Rahardjo Budianto Jenny Lauvita Jusni, Louis Fabio Jonathan Kartika, Ronald Winardi Kris Herawan Timotius Linawati Hananta, Linawati Lorettha Wijaya Maria Dara Novi Handayani, Maria Dara Novi Narwati, Yulia Tanti Natasha, Tiffanie Nawanto Agung Prastowo Panggabean, Nadine Lefina Poppy Kristina Sasmita R. Budianto, Iskandar Riki Tenggara Rita Dewi Santi, Bryani Titi Sartika, Chyntia Retna Sasmita, Poppy K. Steven, Andreas Sugiharto, Liliana Sulichatiani Sutino, Vinsensius Syarief Darmawan Sylvia Wijaya Sylvia Wijaya Tri Isyana Tungga Dewi Tri Isyani Tungga Dewi Veronika Maria Sidharta Vienna Christantia Yauwono, Anthony Zita Arieselia