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Journal : Jurnal Buana Farma

EVALUASI RASIONALITAS PENGGUNAAN ANTIBIOTIK PASIEN PNEUMONIA DI RS TIPE B KOTA BOGOR Septiani, Wulan; Rosiana, Rosiana; Dewi, Masita Sari; Marselina, Marselina
Jurnal Buana Farma Vol. 5 No. 3 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i3.1509

Abstract

Pneumonia remains one of the leading causes of morbidity and mortality worldwide. Inappropriate use of antibiotics can increase the risk of bacterial resistance. Rationality evaluation is essential to ensure appropriate selection, dosage, and duration of therapy. This study aimed to describe the characteristics of pneumonia patients, antibiotic prescribing patterns, and their rational use in the inpatient ward of Type B Hospital in Bogor City in 2024. A retrospective descriptive design was employed using medical records of 83 pneumonia patients from January to December 2024. Data were analyzed descriptively, and rationality was assessed using the Gyssens method based on the Ministry of Health Regulation No. 28 of 2021. The results showed that most patients were aged ≥60 years (41.0%) and male (51.8%). The most commonly used antibiotics were ceftriaxone (57.9%) and levofloxacin (20.0%). Category 0 (appropriate) accounted for 55.6%, while 44.4% were inappropriate, mainly IVa (23.3%) and IIIb (10.0%). Conclusion: Improving rationality requires regular evaluation, clinical pathways, and antimicrobial stewardship programs.
TINGKAT PENGETAHUAN DAN KEPATUHAN TERHADAP KUALITAS HIDUP PASIEN TUBERKULOSIS DI PUSKESMAS CIKARANG Damayanti, Nanda; Dewi, Masita Sari; Adiwisastra, Nuzul Gyanata; Rosiana, Rosiana
Jurnal Buana Farma Vol 5 No 4 (2025): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i4.1542

Abstract

Tuberculosis (TB) remains a major public health problem in Indonesia, including Bekasi Regency, which has a high disease burden. A decline in quality of life is commonly experienced by TB patients due to clinical symptoms, social stigma, and adverse drug effects. Although patient knowledge and treatment adherence are widely believed to influence therapeutic outcomes, evidence regarding their impact on quality of life remains inconsistent and limited, particularly in the Cikarang region. This study aimed to examine the relationship between knowledge level and treatment adherence with the quality of life of pulmonary tuberculosis patients at Puskesmas Cikarang Utara. A cross-sectional design was employed involving 93 outpatient pulmonary TB patients who met the inclusion criteria, including age 17–65 years, undergoing category I/II therapy, able to communicate, and willing to participate, as well as exclusion criteria of having significant comorbid conditions. Participants were selected using purposive sampling. Data were collected using a structured knowledge questionnaire, the Morisky Medication Adherence Scale (MMAS-8), and the Short Form-36 (SF-36). Statistical analysis was performed using the Chi-Square test. The majority of respondents demonstrated good knowledge (86%), moderate to high treatment adherence (86%), and a high quality of life (55.9%). Chi-Square analysis indicated no significant association between knowledge level and quality of life (p = 0.468), nor between treatment adherence and quality of life (p = 0.962). These findings suggest that knowledge and adherence alone are insufficient determinants of quality of life among pulmonary TB patients. Therefore, improving patients’ quality of life requires comprehensive interventions. Beyond treatment adherence.