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Journal : Multidisciplinary Indonesian Center Journal

THE EFFECT OF GIVING GREEN BETEL LEAF EXTRACT ON THE GROWTH OF Bacteroides IN VAGINAL SECRET CULTURE Nuraini, Deswinda Fadhilah; Yanti, Ni Luh Gede Puspita; Parwati, Putu Ayu; Prihatiningsih, Diah
Multidisciplinary Indonesian Center Journal (MICJO) Vol. 2 No. 4 (2025): Vol. 2 No. 4 Edisi Oktober 2025
Publisher : PT. Jurnal Center Indonesia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62567/micjo.v2i4.1277

Abstract

Green betel leaves contain compounds that can treat vaginal discharge, especially those caused by bacteria. To determine the effect of green betel leaf extract on the growth of Bacteroides in vaginal secretion cultures, this study used a quantitative experimental method, where vaginal secretion samples were taken from the subjects and then tested quantitatively. There were two data collection techniques used in this study: using a questionnaire and testing vaginal secretion samples with green betel leaf extract. The test for using was diffusion (paper disc) for the antibacterial test. The media used was MHA. The positive control used was a blank disc, the extract concentration series used were 20%, 25% and 30%. The diameter of the inhibition zone was observed and then analyzed. The results of the t-test analysis showed that the significance value was 0.00 <0.05, so H0 was rejected Ha was accepted or it could be concluded that there was a difference in the effect of giving green betel leaf extract on the growth of Bacteroides in vaginal secretion culture. Antibacterial activity test of green betel leaves (Piper betle L) against Bacteroides bacteria that cause Bacterial Vaginosis, namely resistant at a concentration of 20%, intermediate at a concentration of 25% and sensitive at a concentration of 30%. Green betel leaf extract (Piper betle L) has inhibitory power against Bacteroides bacteria that cause Bacterial Vaginosis. Can increase the concentration series of methanol extract of green betel leaves, find the minimum bactericidal concentration (MBC) and the maximum inhibitory concentration (MIC) of green betel leaf extract against Bacteroides bacteria that cause Bacterial Vaginosis
PENILAIAN HASIL CYSTATIN C PADA PASIEN GANGGUAN FUNGSI GINJAL DI LABORATORIUM PRODIA CIBUBUR Aminah, Aminah; Parwati, Putu Ayu; Pamungkas, Moh. Adreng; Prihatiningsih, Diah
Multidisciplinary Indonesian Center Journal (MICJO) Vol. 1 No. 3 (2024): Vol. 1 No. 3 Edisi Juli 2024
Publisher : PT. Jurnal Center Indonesia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62567/micjo.v1i3.171

Abstract

Kidney function disorders refer to a condition where the kidneys' ability to filter metabolic waste from the blood and excrete it through urine is compromised. Cystatin C serves as a sensitive and specific biomarker for measuring glomerular filtration rate, accurately reflecting kidney function. This study aims to evaluate Cystatin C levels based on gender among patients with kidney function disorders at the Prodia Cibubur clinic laboratory. The research was conducted from February to March 2023 using a descriptive cross-sectional approach. The sample comprised 120 patients with kidney function disorders selected through total sampling. The findings indicate that 16 patients (13.3%) had normal Cystatin C levels, while 104 patients (86.7%) had elevated Cystatin C levels. Notably, among males, 61 individuals (50.8%) tended to exhibit higher Cystatin C levels, suggesting a greater potential for kidney function disorders due to factors such as activity intensity, body mass influence, and hormonal factors.