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Yanthy Susanti
Sekolah Tinggi Ilmu Kesehatan IKIFA
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DETEKSI BAHAN KIMIA OBAT PADA JAMU PEGAL LINU: KAJIAN AUTENTIKASI MENGGUNAKAN KROMATOGRAFI LAPIS TIPIS Pra Panca Bayu Chandra; Yanthy Susanti; Edo Gumelar; Senny Listy Kartika Falestin
IONTech Journal Vol 7 No 2 (2026): Agustus 2026
Publisher : Institut Sains dan Teknologi Al-Kamal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62702/iontech.v7i2.199

Abstract

High public interest in traditional medicines is partly driven by the perception that herbal medicines are safer and more affordable than modern pharmaceuticals. However, this condition may be exploited by irresponsible manufacturers who illegally add medicinal chemicals to traditional herbal products. One of the medicinal chemicals reported in pegal linu herbal medicines is paracetamol. Improper use of paracetamol may increase the risk of toxicity, particularly hepatotoxicity. This study aimed to identify the presence of paracetamol in pegal linu herbal medicines circulating at Deprok Market, Cipinang Muara, using Thin-Layer Chromatography (TLC). A descriptive study was conducted using five pegal linu herbal medicine samples obtained from several herbal medicine retailers through accidental sampling. Identification was performed using silica gel GF254 plates as the stationary phase and a chloroform:methanol (9:1) mixture as the mobile phase. Spots were observed under ultraviolet light at 254 and 366 nm by comparing the retention factor (Rf) values of the samples with those of a paracetamol reference standard and positive controls. The Rf values obtained were 0.80 for sample A, 0.56 for sample B, 0.60 for sample C, 0.34 for sample D, and 0.44 for sample E. The presence of paracetamol was determined based on the similarity of the Rf values between the samples, reference standard, and positive control under the same TLC conditions.
Co-Authors Edo Gumelar Pra Panca Bayu Chandra Senny Listy Kartika Falestin